Articles

Screening and systematic follow-up for cardiopulmonary comorbidity in elective surgery for colorectal cancer: a randomised feasibility study

One third of patients with colorectal cancer (CRC) have comorbidity, which impairs their postoperative outcomes. Scoring systems may predict mortality, but there is limited evidence of effective interventions ...

Authors: Hans B. Rahr, Susanna Streym, Charlotte G. Kryh-Jensen, Helene T. Hougaard, Anne S. Knudsen, Steffen H. Kristensen and Ejler Ejlersen

Repeat liver resection for pure large cell neuroendocrine carcinoma of the gallbladder: a favorable outcome

The pure large cell type is a rare variant of primary neuroendocrine carcinoma of the gallbladder. Few reports have mentioned extended survival. Although a multimodal treatment has been described in the treatm...

Authors: Ahmad Abutaka, Moamena El-Matbouly, Irfan Helmy, Walid Elmoghazy, Ibnouf Sulieman, Mohamed Ben Gashir, Madiha Soofi, Hatem Khalaf and Ahmed Elaffandi

Risk factors for febrile neutropenia and effectiveness of primary prophylaxis with pegfilgrastim in patients with esophageal cancer treated with docetaxel, cisplatin, and 5-fluorouracil

The docetaxel, 5-fluorouracil, and cisplatin (DCF) regimen is an effective form of chemotherapy for advanced esophageal cancer. However, the incidence of adverse events such as febrile neutropenia and hematolo...

Authors: Yu Ohkura, Masaki Ueno and Harushi Udagawa

Is hepatic artery coil embolization useful in distal pancreatectomy with en bloc celiac axis resection for locally advanced pancreatic cancer?

The exact contribution of preoperative coil embolization in distal pancreatectomy with en bloc celiac axis resection (DP-CAR) for the prevention of ischemic liver complication is not fully elucidated.

Authors: Atsuhiko Ueda, Nozomu Sakai, Hideyuki Yoshitomi, Katsunori Furukawa, Tsukasa Takayashiki, Satoshi Kuboki, Shigetsugu Takano, Daisuke Suzuki, Shingo Kagawa, Takashi Mishima, Eri Nakadai, Masaru Miyazaki and Masayuki Ohtsuka

Surgery for gastrointestinal metastases of malignant melanoma — a retrospective exploratory study

Cutaneous melanoma has a rapidly increasing incidence in Sweden, and it has more than doubled in the last two decades. In recent years, new systemic treatments for patients with metastatic disease have increas...

Authors: Carl Jacob Holmberg, Gulan Alwan, Lars Ny, Roger Olofsson Bagge and Dimitrios Katsarelias

Prognostic significance of Human epidermal growth factor receptor-2 expression in patients with resectable gastric adenocarcinoma

The purpose of this study was to investigate the correlation between human epidermal growth factor receptor 2 (HER2) overexpression and clinicopathologic factors and overall survival rate in patients who under...

Authors: Hyeongbin Kim, SangHyuk Seo, KwangHee Kim, Yo-Han Park, MinSung An, HyungJoo Baik, ChangSoo Choi and SangHoon Oh

Rare breast and subcutaneous metastases from pancreatic neuroendocrine tumor: a case report

Neuroendocrine tumors are a group of rare neoplasms, and the pancreatic neuroendocrine tumors (PNETs) represent only 1–2% of all pancreatic malignant tumors. The most common sites of these tumors include the g...

Authors: Dorotea Bosco, Salvatore Perrotti, Corrado Spatola, Giada Maria Vecchio, Rosalia Latino and Antonio Di Cataldo

Bacterial colonization of seromas after breast cancer surgery with and without local steroid prophylaxis

Seroma formation is a frequent postoperative sequela after mastectomy for primary breast cancer. We investigated the role of bacterial colonization of seroma fluid with three different culture methods and the ...

Authors: Christen Kirk Axelsson, Gro Maria Qvamme, Mette Okholm, Charlotte Lanng, Magnus Arpi, Minea Bruusgaard Mortensen, Birgitte Wegeberg and Pal Bela Szecsi

Retraction Note: Diagnostic and prognostic value of plasma microRNA-195 in patients with non-small cell lung cancer

This article [1] is retracted at the request of Editor-in-Chief due to overlap with articles [2–5].

Authors: Keli Su, Tingcui Zhang, Yongrui Wang and Guijun Hao

A prospective, randomised double-blind study on the anaesthetic effect of dexmedetomidine hydrochloride in brainstem tumour surgery

Brainstem tumour surgery is difficult, and accidents can easily occur.

Authors: Sheng-Xiang Wu and Hua-Qin Chen

Intrapancreatic accessory spleen false positive to 68Ga-Dotatoc: case report and literature review

Intrapancreatic accessory spleen (IPAS) is an uncommon finding of pancreatic mass. Differential diagnosis with pancreatic tumor, especially with non-functional neuroendocrine tumor (NF-NET), may be very hard a...

Authors: Francesco Lancellotti, Luca Sacco, Saverio Cerasari, Vittoria Bellato, Simone Cicconi, Antonio Ciardi, Edoardo Maria Muttillo, Tiziana Feola, Roberto Caronna and Piero Chirletti

A systematic review of the comparison of the incidence of seeding metastasis between endoscopic biliary drainage and percutaneous transhepatic biliary drainage for resectable malignant biliary obstruction

Endoscopic biliary drainage (EBD) and percutaneous biliary drainage (PTBD) are the two main strategies of preoperative biliary drainage (PBD) for resectable malignant biliary obstruction (MBO) worldwide, but w...

Authors: Lei Wang, Nanping Lin, Fuli Xin, Qiao Ke, Yongyi Zeng and Jingfeng Liu

Divergent immunohistochemical expression of CD21 and CD23 by follicular dendritic cells with increasing grade of follicular lymphoma

Ultrastructural and immunohistochemical differences have been described in FDCs of primary and secondary follicles, illustrating the highly compartmentalized structure of lymph follicles. Differences in FDC im...

Authors: Fisnik Kurshumliu, Fatlinda Sadiku-Zehri, Ardita Qerimi, Zana Vela, Fisnik Jashari, Samir Bytyci, Vlore Rashiti and Shemsedin Sadiku

Short-term evaluation of immune levels and nutritional values of EN versus PN in gastric cancer: a systematic review and a meta-analysis

Postsurgical patients’ oral feeding begins with clear fluids 1–3 days after surgery. This might not be sufficiently nutritious to boost the host immune system and provide sufficient energy in gastric neoplasti...

Authors: Fan Xin, Said Abdulrahman Salim Mzee, Godwin Botwe, Han He, Sun Zhiyu, Chen Gong, Said Twahir Said and Chen Jixing

A type of neoplasia deadlier than gastric adenocarcinoma? Report of a case of primary gastric squamous cell carcinoma

Primary gastric squamous cell carcinoma is an extremely rare malignancy with few case reports reported so far in the current medical literature. Its incidence varies between 0.04 and 0.07% of all gastric malig...

Authors: Michail G. Vailas, Athanasios Syllaios, Natasha Hasemaki, Maria Sotiropoulou, Eustratia Mpaili, Helen Sarlanis, Evangelos Felekouras and Alexandros Papalampros

Predictive risk factors for anastomotic leakage after anterior resection of rectal cancer in elderly patients over 80 years old: an analysis of 288 consecutive patients

Anastomotic leakage (AL) is a common complication after anterior resection of rectal cancer. Few studies have been conducted to determine whether the traditional predictors of AL can be applied to elderly pati...

Authors: Sicheng Zhou, Haitao Zhou, Zhaoxu Zheng, Jianwei Liang, Zhixiang Zhou and Xishan Wang

Comparison of retroperitoneal laparoscopic versus open adrenalectomy for large pheochromocytoma: a single-center retrospective study

It remains unclear whether retroperitoneal laparoscopic adrenalectomy (RLA) is safe and effective for the treatment of large pheochromocytoma (PHEO). This retrospective study aimed to identify the advantages a...

Authors: Wei Zhu, Shaogang Wang, Guanghui Du, Hailang Liu, Jinjin Lu and Weimin Yang

The impact of pharmacological thromboprophylaxis and disease-stage on postoperative bleeding following colorectal cancer surgery

Pharmacological thromboprophylaxis after colorectal cancer (CRC) surgery is internationally recommended for venous thromboembolism (VTE) prevention. The aim of this retrospective study was to evaluate the risk...

Authors: Hiroyuki Ohta, Toru Miyake, Tomoharu Shimizu, Hiromichi Sonoda, Tomoyuki Ueki, Sachiko Kaida, Tsuyoshi Yamaguchi, Hiroya Iida and Masaji Tani

Giant villous adenoma of rectum- what is the malignant potential and what is the optimal treatment? A case and review of literature

Villous adenomas are dubiously benign lesions, which are difficult to interpret because of their malignant potential. Distal villous adenomas present with bleeding or mucus discharge. Giant adenomas are not am...

Authors: Lovenish Bains, Pawanindra Lal, Anubhav Vindal and Meeta Singh

The neutrophil/lymphocyte ratio as a predictor of peritoneal metastasis during staging laparoscopy for advanced gastric cancer: a retrospective cohort analysis

The use of staging laparoscopy (SL) has become widespread in patients with advanced gastric cancer (GC). This study aimed to evaluate the predictive value of the neutrophil/lymphocyte ratio (NLR) for the prese...

Authors: Naohiko Nakamura, Shinichi Kinami, Yoritaka Fujii, Seiko Miura, Jun Fujita, Daisuke Kaida, Yasuto Tomita, Takashi Miyata, Hideto Fujita, Nobuhiko Ueda, Yasuo Iida and Takeo Kosaka

Shoulder girdle resection: surgical technique modification and introduction of a new classification system

Different classification systems for surgical tumor resections in the proximal humerus and scapula have been described, but none are specific or have been recently revised. The purpose of this article is to re...

Authors: Ahmad Shehadeh, Ahmad Ja’afar, Ula Isleem, Anas Hamad and Ahmed Salem

Analysis of the clinical efficacy of tumor resection methods used in 20 patients with clavicular tumor

To retrospectively analyze the tumor resection method used in 20 patients with clavicular tumors and evaluate its clinical efficacy.

Authors: Yun Liu, Xian-Ying Huang, Wen-Yu Feng, Xiao-Ting Luo, Chang-Wu Wei, Jian-Hong Liu, Yin-Juan Lai, Zeng-Ming Xiao, Xiao Zhang and Xin-Li Zhan

Retraction Note: Decreased miR-154 expression and its clinical significance in human colorectal cancer

The Editor-in-Chief is retracting this article [1] due to overlap with the following articles (amongst others) [2–6].

Authors: Yang Kai, Cheng Qiang, Pan Xinxin, Zhou Miaomiao and Lin Kuailu

Retraction Note: Decreased microRNA-452 expression and its prognostic significance in human osteosarcoma

The Editor-in-Chief is retracting this article [1] due to overlap with previously published articles [2, 3]. Fig. 3D “miR-452 mimics” is very similar to Fig. 3D “si-BANCR” in article [2]. Fig. 3D “miRNC” is ve...

Authors: Ren-Zeng Li and Li-Min Wang

Expression of Concern to: Increased expression of LncRNA BANCR and its prognostic significance in human hepatocellular carcinoma

Authors: Tao Zhou and Yanjing Gao

Expression of Concern to: Decreased miR-198 expression and its prognostic significance in human gastric cancer

Authors: Zhigang Cui, Xin Zheng and Di Kong

Retrograde installation of percutaneous transhepatic negative-pressure biliary drainage stabilizes pancreaticojejunostomy after pancreaticoduodenectomy: a retrospective cohort study

Leakage from the pancreatoenteric anastomosis has been one of the major complications of pancreaticoduodenectomy (PD). The aim of this study was to investigate the feasibility of retrograde installation of per...

Authors: Chang Min Lee, Yong Joon Suh and Sam-Youl Yoon

Optimal indication criteria for neoadjuvant chemotherapy in patients with resectable colorectal liver metastases

There are no optimal indication criteria for neoadjuvant chemotherapy (NAC) in patients with resectable colorectal liver metastases (CLM). The aim of this study was to prospectively assess the survival benefit...

Authors: Hirofumi Ichida, Yoshihiro Mise, Hiromichi Ito, Takeaki Ishizawa, Yosuke Inoue, Yu Takahashi, Eiji Shinozaki, Kensei Yamaguchi and Akio Saiura

Hepatectomy for metachronous colorectal liver metastases following complete cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for peritoneal metastases: a report of three cases

Cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) for peritoneal metastasis (PM) from colorectal cancer (CRC) has been reported to substantially improve the prognosis and the q...

Authors: Kyoji Ito, Nobuyuki Takemura, Fuyuki Inagaki, Fuminori Mihara, Toshiaki Kurokawa, Yoshimasa Gohda, Tomomichi Kiyomatsu, Hideaki Yano and Norihiro Kokudo

Microwave ablation compared with hepatic resection for the treatment of hepatocellular carcinoma and liver metastases: a systematic review and meta-analysis

Hepatic resection (HR) is the gold standard liver cancer treatment, but few patients are eligible due to comorbidities or tumor location. Microwave ablation (MWA) is an important complementary liver cancer tre...

Authors: Mrudula B. Glassberg, Sudip Ghosh, Jeffrey W. Clymer, George W. J. Wright, Nicole Ferko and Joseph F. Amaral

Immunologic cellular characteristics of the tumour microenvironment of hepatocellular carcinoma drive patient outcomes

Anti-tumour immune competence has an impact in hepatocarcinogenesis and success of anti-cancer therapies. Tumour-infiltrating lymphocytes (TILs) and monocytes/macrophages (TAMs) are proposed to have significan...

Authors: Georgi Atanasov, Karoline Dino, Katrin Schierle, Corinna Dietel, Gabriela Aust, Johann Pratschke, Daniel Seehofer, Moritz Schmelzle and Hans-Michael Hau

Patient satisfaction after unilateral oncoplastic volume displacement surgery for breast cancer, evaluated with the BREAST-Q™

Oncoplastic breast-conserving surgery allows larger resections in unfavorable locations, with an improved chance of preserving esthetics. Indications and timing for potential contralateral surgery to obtain sy...

Authors: Anna Gardfjell, Cecilia Dahlbäck and Kristina Åhsberg

Effect of clinical status on survival in patients with borderline or locally advanced pancreatic adenocarcinoma

To determine the effect of clinical status (weight variation and performance status [PS]) at diagnosis and during induction treatment on resectability and overall survival (OS) rates in patients with borderlin...

Authors: Pauline Duconseil, Jonathan Garnier, Victoria Weets, Jacques Ewald, Ugo Marchese, Marine Gilabert, Laurence Moureau-Zabotto, Flora Poizat, Marc Giovannini, Jean-Robert Delpero and Olivier Turrini

Short-term outcomes of traction-assisted versus conventional endoscopic submucosal dissection for superficial gastrointestinal neoplasms: a systematic review and meta-analysis of randomized controlled studies

In recent years, some traction-assisted approaches have been introduced to facilitate endoscopic submucosal dissection (ESD) procedures by reducing the procedure time and risks related to the procedure. Howeve...

Authors: Mengting Xia, Yunfeng Zhou, Jiajie Yu, Wenwen Chen, Xiaotao Huang and Juan Liao

Comparing the cytotoxicity of taurolidine, mitomycin C, and oxaliplatin on the proliferation of in vitro colon carcinoma cells following pressurized intra-peritoneal aerosol chemotherapy (PIPAC)

Besides its known antibacterial effect commonly used in intraperitoneal lavage, taurolidine has been observed to possess antineoplastic properties. In order to analyse this antineoplastic potential in a pallia...

Authors: Justyna Schubert, Veria Khosrawipour, Haris Chaudhry, Mohamed Arafkas, Wolfram Trudo Knoefel, Alessio Pigazzi and Tanja Khosrawipour

Optimal use of antiplatelet agents, especially aspirin, in the perioperative management of colorectal cancer patients undergoing laparoscopic colorectal resection

Laparoscopic abdominal surgery is considered superior to open surgery. However, efficacy and safety outcomes of laparoscopic surgery in colorectal cancer (CRC) are unclear, particularly in patients undergoing ...

Authors: Yasunori Yoshimoto, Takahisa Fujikawa, Akira Tanaka, Hideto Hayashi, Norihiro Shimoike, Hiroshi Kawamoto, Chiyo Nakasuga and Tsunenori Yamamoto

Which papillary thyroid microcarcinoma should be treated as “true cancer” and which as “precancer”?

Papillary thyroid microcarcinoma (PTMC) generally is a cancer with excellent prognosis, but the term “cancer” sounds severe and harsh, which can elicit emotional and physical responses from patients. To elimin...

Authors: Krzysztof Kaliszewski, Dorota Diakowska, Beata Wojtczak, Zdzisław Forkasiewicz, Dominika Pupka, Łukasz Nowak and Jerzy Rudnicki

Dermatofibrosarcoma protuberans: surgical management of a challenging mesenchymal tumor

Dermatofibrosarcoma protuberans (DFSP) is a rare, low-grade malignant mesenchymal tumor of the soft tissue, characterized by slow infiltrative growth and common local recurrence, with rare distant metastases.

Authors: Felix Wiesmueller, Abbas Agaimy, Aristotelis Perrakis, Andreas Arkudas, Raymund E. Horch, Robert Grützmann and Nikolaos Vassos

Analysis of patients scheduled for neoadjuvant therapy followed by surgery for esophageal cancer, who never made it to esophagectomy

Neoadjuvant treatment followed by esophagectomy is standard practice in locally advanced esophageal cancer. However, not all patients who started neoadjuvant treatment will undergo esophageal resection. The pu...

Authors: Lieven Depypere, Melissa Thomas, Johnny Moons, Willy Coosemans, Toni Lerut, Hans Prenen, Karin Haustermans, Hans Van Veer and Philippe Nafteux

Radiolocalization of atypical lesions for intraoperative identification: technical factors, localization quality, success rates, patient safety, and spectrum of applications

To retrospectively analyze perilesional technetium Tc-99m MAA injection for intraoperative localization of atypical soft-tissue and bone lesions within a single tertiary referral center in order to determine t...

Authors: Jason R. Young, Andi E. Wallig, Nichole L. Fischer, Tiffinee N. Swanson, Mark J. Truty, K. Robert Shen and Brendan P. McMenomy

Thoracoscopy resection of a giant solitary fibrous tumor with double pedicles and double blood supply: a case report

Solitary fibrous tumors are rare tumors derived from the pleura. A tumor generally has only one pedicle. Video-assisted thoracoscopic surgery is generally used when a tumor is small (< 10 cm), and traditional ...

Authors: Yi Shen, Tao He, Ping Lu, Guobin Feng, Jun Zhu and Xiangan Wang

Comparative analysis of robotic gastrectomy and laparoscopic gastrectomy for gastric cancer in terms of their long-term oncological outcomes: a meta-analysis of 3410 gastric cancer patients

Data regarding the long-term oncological outcomes of robotic gastrectomy (RG) are limited despite the increased commonality of this method as an alternative for gastric cancer treatment. Here, we conducted a m...

Authors: Guixiang Liao, Zhihong Zhao, Muhammad Khan, Yawei Yuan and Xianming Li

The prognostic value of tumor-infiltrating lymphocytes in colorectal cancer differs by anatomical subsite: a systematic review and meta-analysis

In colorectal cancer (CRC), whether the immune score can be used to predict the clinical prognosis of the patient has not been completely established. Besides, the prognostic values of tumor-infiltrating lymph...

Authors: Yamei Zhao, Xiaoxu Ge, Jiawei He, Yi Cheng, Zhanhuai Wang, Jian Wang and Lifeng Sun

Lenvatinib complementary with radioiodine therapy for patients with advanced differentiated thyroid carcinoma: case reports and literature review

The prognosis for patients with advanced differentiated thyroid carcinoma (ADTC) with disseminated distant metastases is very poor. Tyrosine kinase inhibitors targeting tumor angiogenesis have been shown to im...

Authors: Nai-Wei Sheu, He-Jiun Jiang, Che-Wei Wu, Feng-Yu Chiang, Hsin-Ying Clair Chiou and Pi-Jung Hsiao

Peritoneal carcinomatosis index predicts survival in colorectal patients undergoing HIPEC using oxaliplatin: a retrospective single-arm cohort study

Peritoneal carcinomatosis (PC) from colorectal cancer is associated with poor prognosis. Cytoreductive surgery (CRS) combined with hyperthermic intraperitoneal chemotherapy (HIPEC) has improved survival for pa...

Authors: Atuhani Burnett, Marie-Eve Aubé Lecompte, Nora Trabulsi, Pierre Dubé, Mai-Kim Gervais, Bertrand Trilling, Alexis-Simon Cloutier and Lucas Sideris

Cervical spine giant cell bone tumor: a case report

Giant cell tumors (GCTs) of the bone are locally aggressive primary bone tumors with a benign character. Spinal involvement is rare and they are quite rare in the cervical spine.

Authors: İdris Sertbaş, Mete Karatay and Uguray Payam Hacisalihoğlu

Laparoscopic pancreaticoduodenectomy: are the best times coming?

The introduction of laparoscopic technology has greatly promoted the development of surgery, and the trend of minimally invasive surgery is becoming more and more obvious. However, there is no consensus as to ...

Authors: Mengqi Liu, Shunrong Ji, Wenyan Xu, Wensheng Liu, Yi Qin, Qiangsheng Hu, Qiqing Sun, Zheng Zhang, Xianjun Yu and Xiaowu Xu

Associations between lymphovascular space invasion, nodal recurrence, and survival in patients with surgical stage I endometrioid endometrial adenocarcinoma

To investigate the predictive value of lymphovascular space invasion (LVSI) for nodal recurrence and overall survival (OS) in patients with stage I endometrioid endometrial cancer (EC) following surgical stagi...

Authors: Ashley E. Veade, Jonathan Foote, Jessie Ehrisman, Gloria Broadwater, Brittany A. Davidson, Paula S. Lee, Angeles Alvarez Secord, Andrew Berchuck and Laura J. Havrilesky

A rare case of bipartite combined tumour of the oesophagus

Bipartite combined oesophageal tumours are an exceedingly rare entity and much less is known about the natural history of these tumours following curative surgery. The authors present a case of a bipartite com...

Authors: Nicholette Goh, Danson Xue Wei Yeo, Sanghvi Kaushal Amitbhai, Myint Oo Aung, Yong Howe Ho, Aaryan Nath Koura and Jaideepraj Rao

Association between serum zinc levels and lung cancer: a meta-analysis of observational studies

Inconsistent results according to numerous studies that had investigated the association between serum zinc levels and lung cancer risk were reported. The aim of this study was to explore whether serum zinc le...

Authors: Ying Wang, Zhengyi Sun, Aipeng Li and Yongsheng Zhang