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  1. Anastomotic blood supply is vital to anastomotic healing. The aim of this study was to demonstrate the effect of the left colic artery (LCA) on blood supply in the anastomotic area, explore the relationship be...

    Authors: Bo Li, Jianan Wang, Shaohui Yang, Jie Shen, Qi Li, Qiqi Zhu and Wei Cui
    Citation: World Journal of Surgical Oncology 2022 20:313
  2. The purpose of this study was to describe a surgical technique of bone resection with periosteal preservation and reconstruction in patients with high-grade bone malignant tumors and to determine its effect on...

    Authors: Mahmoud Smida, Ameni Ammar, Faten Fedhila, Wiem Douira and Samia Sassi
    Citation: World Journal of Surgical Oncology 2022 20:312
  3. Additional surgery is recommended after non-curative endoscopic submucosal dissection for early gastric cancer. However, it is not easy to recommend for tumors located in the upper third of the stomach, becaus...

    Authors: Sin Hye Park, Hong Man Yoon, Keun Won Ryu, Young-Woo Kim, Myeong-Cherl Kook and Bang Wool Eom
    Citation: World Journal of Surgical Oncology 2022 20:311
  4. Intraductal papillary mucinous neoplasms (IPMNs) are characterized by their abundant mucin production and malignant potential. IPMNs of the pancreas are mainly managed according to their radiographic indicatio...

    Authors: Yunzhen Qian, Yitao Gong, Guopei Luo, Yu Liu, Ruijie Wang, Xuan Zou, Shengming Deng, Xuan Lin, Yusheng Chen, Xu Wang, Xianjun Yu, He Cheng and Chen Liu
    Citation: World Journal of Surgical Oncology 2022 20:310
  5. Preoperative absolute lymphocyte count (LC) and fibrinogen (FIB) are useful prognostic indicators in colorectal cancer (CRC). However, the prognostic value of the LC to FIB ratio (LFR) has never been addressed.

    Authors: Xiang Huang, Yu Huan, Long Liu, Qianwen Ye, Jian Guo and Bing Yan
    Citation: World Journal of Surgical Oncology 2022 20:309
  6. Pylorus-preserving gastrectomy (PPG) is a function-preserving surgery for the treatment of early gastric cancer (EGC) in the middle third of the stomach. According to the literature reports, PPG decreases the ...

    Authors: Sen Hou, Fan Liu, Zhidong Gao and Yingjiang Ye
    Citation: World Journal of Surgical Oncology 2022 20:308
  7. This article is a response to “comment on ‘Pooled analysis of Xpert bladder cancer based on the 5 mRNAs for rapid diagnosis of bladder carcinoma’” by Gopal Sharma. With this comment, author highlighted the str...

    Authors: Yu-Fei Xie, Ye-Ling Liu and Xu-Guang Guo
    Citation: World Journal of Surgical Oncology 2022 20:306
  8. As transanal total mesorectal excision (taTME) is performed worldwide, the optimization of existing training and guidance programs to enhance new taTME learners’ competence in performing this procedure is warr...

    Authors: Fengming Xu, Yiqiao Zhang, Jiafu Yan, Bowen Xu, Guocong Wu, Zhengyang Yang, Liting Sun, Xiao Zhang, Hongwei Yao and Zhongtao Zhang
    Citation: World Journal of Surgical Oncology 2022 20:305
  9. Tumor deposits (TDs) have been identified as an independent prognostic factor in gastric cancer (GC). However, the associated clinicopathological factors and how to simply and reasonably incorporate TD into th...

    Authors: Menglong Zhou, Wang Yang, Wei Zou, Jianing Yang, Changming Zhou, Zhiyuan Zhang, Yaqi Wang, Jing Zhang, Yan Wang, Guichao Li, Zhen Zhang and Fan Xia
    Citation: World Journal of Surgical Oncology 2022 20:304
  10. Increasing evidences have revealed the tumor immune microenvironment not only has vital impacts on the origin, progression, and metastasis of tumors significantly but also influences the response to immunother...

    Authors: Dong Dong, Wei Wang, Heng Wang, Liang Chen and Tianyi Liu
    Citation: World Journal of Surgical Oncology 2022 20:303
  11. India encountered two waves of COVID-19 pandemic with variability in its characteristics and severity. Concerns were raised over the safety of treatment, and higher morbidity was predicted for oncological surg...

    Authors: Kishan Soni, J. F. Neville, Roli Purwar, Tarun Kumar, Ghanshyam Yadav, Nimisha Verma and Manoj Pandey
    Citation: World Journal of Surgical Oncology 2022 20:302
  12. Upregulation of Stathmin 1 (STMN1), a cytoplasmic phosphoprotein that controls the dynamics of cellular microtubules, is linked to malignant behavior and poor prognosis in a range of malignancies. However, lit...

    Authors: En-di Zhang, Chenxuan Li, Yuan Fang, Na Li, Zhongyun Xiao, Chuhong Chen, Benkai Wei, Hangping Wang, Jincheng Xie, Yinglei Miao, Zhong Zeng and Hanfei Huang
    Citation: World Journal of Surgical Oncology 2022 20:301
  13. National lead time goals have been implemented across Sweden to standardize and improve cancer patient care. However, the prognostic impact of lead times has not yet been studied in patients with colorectal ca...

    Authors: Ylva Jansson, Wilhelm Graf and Lana Ghanipour
    Citation: World Journal of Surgical Oncology 2022 20:300
  14. Primary liver cancer is the second-most commonly occurring cancer and has resulted in numerous deaths worldwide. Hepatic resection is of two main types, i.e., anatomic resection (AR) and non-anatomic resection...

    Authors: Xiao-ming Dai, Zhi-qiang Xiang, Qian Wang, Hua-jian Li and Zhu Zhu
    Citation: World Journal of Surgical Oncology 2022 20:299
  15. Hepatocellular carcinoma (HCC) remains a major health problem despite the emergence of several preventive and therapeutic modalities. HCC has heterogeneous and wide morpho-molecular patterns, resulting in uniq...

    Authors: Dina Sweed, Enas Sweed, Inas Moaz, Asmaa Mosbeh, Yahya Fayed, Sara Mohamed Abd Elhamed, Eman Sweed, Mahmoud Macshut, Shimaa Abdelsattar, Shimaa Kilany, Sara A. Saied, Reda Badr, Mahmoud S. Abdallah and Nermine Ehsan
    Citation: World Journal of Surgical Oncology 2022 20:298
  16. Epilepsy is one of the most common glioma complications, and the two may be connected in more ways than we understand. We aimed to investigate the clinical features of glioma-associated epilepsy and explore th...

    Authors: Honglin Ge, Guangfu Di, Zheng Yan, Dongming Liu, Yong Liu, Kun Song, Kun Yang, Xinhua Hu, Zijuan Jiang, Xiao Hu, Lei Tian, Chaoyong Xiao, Yuanjie Zou, Hongyi Liu and Jiu Chen
    Citation: World Journal of Surgical Oncology 2022 20:297
  17. The safe distance between the intraoperative resection line and the visible margin of the distal rectal tumor after preoperative radiotherapy is unclear. We aimed to investigate the furthest tumor intramural s...

    Authors: Ge Sun, Xiaolong Ye, Kuo Zheng, Hang Zhang, Paul Broens, Monika Trzpis, Zheng Lou, Xianhua Gao, Lianjie Liu, Liqiang Hao, Edgar Furnee, Chenguang Bai and Wei Zhang
    Citation: World Journal of Surgical Oncology 2022 20:296
  18. Increasing studies have indicated that noncoding RNA (ncRNA)-mediated competing endogenous RNA (ceRNA) network serves as a significant role in cancer progression, but the underlying regulatory mechanisms of wh...

    Authors: Jianxin Li, Ting Han, Xin Wang, Yinchun Wang, Xuan Chen, Wangsheng Chen and Qingqiang Yang
    Citation: World Journal of Surgical Oncology 2022 20:295
  19. Lymph or chyle leak (LL/CL) is severe complications after lateral cervical lymph node dissection (LLND), mainly due to iatrogenic injury of the lymphatic duct. Efficient and well-operated methods to reduce pos...

    Authors: Ming-Liang Zhang, Lou-Ming Guo, Peng-Cheng Li, Jing-Kang Zhang and Chen-Xu Guo
    Citation: World Journal of Surgical Oncology 2022 20:294
  20. An investigation of the effects of different types of the inferior mesenteric artery (IMA) on laparoscopic left colic artery (LCA) radical resection of rectal cancer was conducted.

    Authors: Jinghao Chen, Meirong Wang, Yuhao Chen, Suying Chen, Jing Xiao, Xiaole Fan, Jushun Yang and Bosheng He
    Citation: World Journal of Surgical Oncology 2022 20:292
  21. SMAD4 is a key mediator of TGFβ signaling and one of the mutated genes in extrahepatic bile duct cancer (eBDC). It has been also reported that SMAD4 has dual functions, in carcinogenesis via silencing and in t...

    Authors: Hirotoshi Takayama, Shogo Kobayashi, Kunihito Gotoh, Kazuki Sasaki, Yoshifumi Iwagami, Daisaku Yamada, Yoshito Tomimaru, Hirofumi Akita, Tadafumi Asaoka, Takehiro Noda, Hiroshi Wada, Hidenori Takahashi, Masahiro Tanemura, Yuichiro Doki and Hidetoshi Eguchi
    Citation: World Journal of Surgical Oncology 2022 20:291
  22. Currently, high or low ligation of the inferior mesenteric artery (IMA) is a controversial issue in laparoscopic radical surgery for colorectal cancer. High or low ligation of the IMA has both advantages and d...

    Authors: Shun Zeng, Wenhao Wu, Xianbin Zhang, Tong Qiu and Peng Gong
    Citation: World Journal of Surgical Oncology 2022 20:290
  23. Alpha‑fetoprotein-producing gastric cancer (AFPGC) is a rare type of gastric cancer with a high rate of metastasis and poor prognosis. Despite substantial progress in the treatment of many solid tumors, there ...

    Authors: Jinyu Xiang, Wenjing Gong, CongCong Wang, Ping Sun and Aina Liu
    Citation: World Journal of Surgical Oncology 2022 20:289
  24. Although syringoma is a common benign tumour of the sudoriferous gland, there is also an extremely rare malignant form known as syringoid eccrine carcinoma (SEC). SEC usually exhibits slow growth with deep inv...

    Authors: Zdeněk Dvořák, Richard Pink, Petr Heinz, Jaroslav Michálek and Petr Krsička
    Citation: World Journal of Surgical Oncology 2022 20:288
  25. Visceral hemangiomatosis is a benign tumor (rarer than hemangioma) that has not been reported to occur in the pancreas, duodenum, or choledoch. It can be easily confused with other pancreatic tumors or choledo...

    Authors: Daguang Tian, Hong Zhu and Xiaoping Wei
    Citation: World Journal of Surgical Oncology 2022 20:286
  26. To provide a rare case of local recurrent Paget’s disease after nipple-sparing mastectomy (NSM) with immediate breast reconstruction with 10 years of disease-free survival and to analyze the clinical and patho...

    Authors: Qian Pu, Qianqian Zhao and Dezong Gao
    Citation: World Journal of Surgical Oncology 2022 20:285
  27. To summarize our clinical experience of cryoablation in renal cell carcinoma (RCC) of Chinese population and to evaluate the long-term outcomes of laparoendoscopic single-site (LESS) cryoablation (LCA) as well...

    Authors: Shangqing Song, Qing Yang, Chengyuan Gu, Guopeng Yu, Bao Hua, Xin Gu, Linhui Wang, Zhong Wang, Guohai Shi and Bin Xu
    Citation: World Journal of Surgical Oncology 2022 20:284
  28. Methyltransferase-like 3 (METTL3) expression could be found in various normal and cancerous tissues. As of now, the clinical significance of METTL3 expression in human pancreatic cancer (PC) tissues still rema...

    Authors: Yuan Li, Hao Huang, Yulan Zhu, Bin Xu, Junjun Chen, Yingting Liu, Xiao Zheng and Lujun Chen
    Citation: World Journal of Surgical Oncology 2022 20:283
  29. The clinical application of robotic-assisted gastrectomy remains controversial, especially as clinical studies of this operation navigated by carbon nanoparticle suspension injection (CNSI) have not been condu...

    Authors: Zhiyan Li, Shichao Ai, Feng Wang, Liang Tao, Feng Sun, Peng Song, Xiaofei Shen, Qiongyuan Hu, Xianghui Li, Song Liu, Meng Wang and Wenxian Guan
    Citation: World Journal of Surgical Oncology 2022 20:282
  30. Venous thromboembolism (VTE) is a threat to the prognosis of tumor patients, especially for critically ill patients. No uniform standard model of VTE risk for critically ill patients with tumors was formatted ...

    Authors: Ruqi Mei, Guodong Wang, Renxiong Chen and Hongzhi Wang
    Citation: World Journal of Surgical Oncology 2022 20:245
  31. This study aimed to investigate the usefulness of computed tomography (CT) texture analysis in the diagnosis of lateral pelvic lymph node (LPLN) metastasis of rectal cancer.

    Authors: Toshihiro Nakao, Mitsuo Shimada, Kozo Yoshikawa, Takuya Tokunaga, Masaaki Nishi, Hideya Kashihara, Chie Takasu, Yuma Wada and Toshiaki Yoshimoto
    Citation: World Journal of Surgical Oncology 2022 20:281
  32. Human apolipoprotein E (APOE) polymorphisms are attributable to the presence of three common alleles, namely, ε2, ε3, and ε4, which generate six genotypes, viz, E2/E2, E2/E3, E3/E3, E3/E4, E4/E4, and E2/E4. APOE ...

    Authors: Caiyan Gan, Yinmei Zhang, Fei Liang, Xuemin Guo and Zhixiong Zhong
    Citation: World Journal of Surgical Oncology 2022 20:280
  33. Cowden syndrome is a rare autosomal-dominant disease with a high risk of malignant tumors of the breast, commonly caused by germline mutations in the PTEN gene. Most breast cancers related to Cowden syndrome show...

    Authors: Aiko Sueta, Masako Takeno, Lisa Goto-Yamaguchi, Mai Tomiguchi, Toko Inao, Mutsuko Yamamoto-Ibusuki and Yutaka Yamamoto
    Citation: World Journal of Surgical Oncology 2022 20:279
  34. In this report, we describe a case of highly advanced hepatocellular carcinoma with tumor thrombosis extending into the main portal vein of the pancreas that was successfully treated with adjuvant lenvatinib a...

    Authors: Hiroyuki Kato, Yukio Asano, Masahiro Ito, Satoshi Arakawa, Masahiro Shimura, Daisuke Koike, Takayuki Ochi, Hironobu Yasuoka, Toki Kawai, Takahiko Higashiguchi, Hiroki Tani, Yoshiki Kunimura, Yuka Kondo, Hidetoshi Nagata, Harunobu Sato and Akihiko Horiguchi
    Citation: World Journal of Surgical Oncology 2022 20:278
  35. Delay from surgery to adjuvant chemotherapy causes impaired survival among patients undergoing radical resection for stage III colon cancer, and the underlying mechanism for this is incompletely clarified. It ...

    Authors: Frans Emland, Helena Taflin, Göran Carlsson, David Ljungman and Elinor Bexe Lindskog
    Citation: World Journal of Surgical Oncology 2022 20:277
  36. Galectins have been recently tackled by many researchers in the field of cancer due to their role in tumorigenesis, disease progression, and metastasis. Thus, they are currently involved in biomarkers research...

    Authors: Radwa Mansour Mohamed, Athar Emam, Mahmoud M. Abdelfattah, Abdel-Mageed Ismail Abdel-Mageed, Mohamed A. Abdelhafeez and Reham Helwa
    Citation: World Journal of Surgical Oncology 2022 20:276
  37. Lung adenocarcinoma (LUAD) accounts for 50% of lung cancers, with high mortality and poor prognosis. Long non-coding RNA (lncRNA) plays a vital role in the progression of tumors. Cuproptosis is a newly discove...

    Authors: Fangwei Wang, Hongsheng Lin, Qisheng Su and Chaoqian Li
    Citation: World Journal of Surgical Oncology 2022 20:275
  38. For sigmoid colon or rectal cancer, a definite consensus regarding the optimal level ligating the inferior mesenteric artery (IMA) has not been reached. We performed this study to determine whether the ligatio...

    Authors: Yawei Wang, Yan Wang, Liaonan Zou, Lingna Deng, Tianchong Wu, Linsen Liu, Jiling Jiang and Tailai An
    Citation: World Journal of Surgical Oncology 2022 20:274
  39. Previous studies have found that lncRNA polymorphisms are associated with the prognosis of gastric cancer (GC), but the specific roles of many lncRNA polymorphism sites in gastric cancer are still unclear. Our...

    Authors: Yanping Lyu, Shuangfeng Yang, Xuejie Lyu, Yuan-Liang Wang, Shumi Ji, Shuling Kang, Yu Jiang, Jianjun Xiang, Chenzhou He, Peixin Li, Baoying Liu and Chuancheng Wu
    Citation: World Journal of Surgical Oncology 2022 20:273
  40. Accurately positioning totally implantable venous access device (TIVAD) catheters and reducing complications in pediatric patients are important and challenging. A number of studies have shown methods for loca...

    Authors: Yuanzhen Chen, Dajun Xing, Lixin Wu, Huatian Lin, Ting Lin, Fang Ding and Liang Xu
    Citation: World Journal of Surgical Oncology 2022 20:272
  41. To investigate the effect and clinical significance of different thoracic surgical approaches for patients with stage IIB–IVA esophageal squamous cell carcinoma on the survival and prognosis of postoperative r...

    Authors: Mingcheng Gao, Yulin Zhu, Yan Gu, Zhan Shi, Jixiang Wu, Huiwen Chang and Jianxiang Song
    Citation: World Journal of Surgical Oncology 2022 20:271
  42. Few studies have evaluated the feasibility and safety of intracorporeal anastomosis (IA) for left hemicolectomy. Here, we aimed to investigate the potential advantages and disadvantages of laparoscopic left he...

    Authors: Li-Ming Wang, Bor-Kang Jong, Chun-Kai Liao, Ya-Ting Kou, Yih-Jong Chern, Yu-Jen Hsu, Pao-Shiu Hsieh, Wen-Sy Tsai and Jeng-Fu You
    Citation: World Journal of Surgical Oncology 2022 20:270
  43. Total laparoscopic pancreaticoduodenectomy (tLPD) for cancer of the Vater remains a challenging procedure. Recently, several meta-analyses showed the superior aspects of “superior mesenteric artery (SMA)-first...

    Authors: Thanh Khiem, Ham Hoi, Tuan Hiep, Kim Khue, Van Duy, Yosuke Inoue, Hong Son and Duc Dung
    Citation: World Journal of Surgical Oncology 2022 20:269
  44. Abnormally expressed in diverse cancers, circZFR has been correlated with clinical outcomes of cancer patients. Aim of this meta-analysis was to elucidate the prognostic role of circZFR in multiple human malig...

    Authors: Zhongyue Liu, Wenchao Zhang, Chao Tu, Wenyi Li, Lin Qi, Zhiming Zhang, Lu Wan, Zhimin Yang, Xiaolei Ren and Zhihong Li
    Citation: World Journal of Surgical Oncology 2022 20:268
  45. The prognosis of patients under existing neoadjuvant chemotherapy or neoadjuvant chemoradiotherapy requires improvement. Whereas programmed cell death 1 (PD-1) inhibitors have shown promising response in advan...

    Authors: Huiru Dai, Minling Liu, Xueying Li, Tingwei Li, Wensheng Huang, Jiehao Liao, Yun Li and Shuo Fang
    Citation: World Journal of Surgical Oncology 2022 20:267
  46. To investigate the role of achaete-scute complex-like 2 (ASCL2) in stomach adenocarcinoma (STAD), we analyze whether ASCL2 suppression could retard cancer development and further observe the relevance between ...

    Authors: Enqi Zheng, Zhun Cai, Wangyong Li, Chuandou Ni and Qian Fang
    Citation: World Journal of Surgical Oncology 2022 20:266
  47. There are no guidelines for straightforwardly managing advanced lung cancer (T3 or T4). Although surgery has traditionally been regarded as the mainstay treatment and the only curative modality, it has limited...

    Authors: Hee Suk Jung and Hyun Jung Kim
    Citation: World Journal of Surgical Oncology 2022 20:265

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