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  1. Colorectal cancer (CRC) poses a heavy threat to human health owing to its high incidence and mortality. Circular RNAs (circRNAs) were investigated to participate in the progression of CRC, whereas there was no...

    Authors: Yanhe Liu, Hui Li, Xiaoyi Ye, Anlong Ji, Xiangwei Fu, Haishan Wu and Xiangyong Zeng

    Citation: World Journal of Surgical Oncology 2020 18:255

    Content type: Research

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  2. Post-chemotherapy retroperitoneal lymph node dissection (pc-RPLND) is one cornerstone in the clinical management of patients with nonseminomatous testicular germ cell tumours (GCT). A wide range of complicatio...

    Authors: Christian Guido Ruf, Simon Krampe, Cord Matthies, Petra Anheuser, Tim Nestler, Jörg Simon, Hendrik Isbarn and Klaus Peter Dieckmann

    Citation: World Journal of Surgical Oncology 2020 18:253

    Content type: Research

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  3. It is unknown whether transmediastinal esophagectomy (TME) is an acceptable surgical procedure for locally advanced esophageal squamous cell carcinoma (ESCC). Therefore, we investigated the feasibility of long...

    Authors: Yukinori Yamagata, Kazuyuki Saito, Kosuke Hirano and Masatoshi Oya

    Citation: World Journal of Surgical Oncology 2020 18:252

    Content type: Research

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  4. It has been demonstrated that simultaneous resection of both primary colorectal lesion and metastatic hepatic lesion is a safe approach with low mortality and postoperative complication rates. However, there a...

    Authors: Long Pan, Chenhao Tong, Siyuan Fu, Jing Fang, Qiuxia Gu, Shufeng Wang, Zhiyu Jiang, Sarun Juengpanich and Xiujun Cai

    Citation: World Journal of Surgical Oncology 2020 18:251

    Content type: Research

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  5. Very rarely does a splenic solitary metastasis arise from a gastric carcinoma because splenic metastasis is usually seen in association with widespread visceral metastasis. Splenectomy is considered to be a cu...

    Authors: Ayato Obana, Nobuo Komatsu, Kazuma Aiba, Shinya Nakanishi, Masakazu Abe, Toshiyuki Yamaguchi, Masahiro Hayashi, Hayato Obi, Masamichi Koyama and Shinichi Hashimoto

    Citation: World Journal of Surgical Oncology 2020 18:250

    Content type: Case report

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  6. Integrating phenotypic and genotypic information to improve prognostic prediction is under active investigation for lung adenocarcinoma (LUAD). In this study, we developed a new prognostic model for event-free...

    Authors: Guofeng Li, Guangsuo Wang, Yanhua Guo, Shixuan Li, Youlong Zhang, Jialu Li and Bin Peng

    Citation: World Journal of Surgical Oncology 2020 18:249

    Content type: Technical innovations

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  7. Ganglioneuromas (GNs) are extremely rare, slowly growing, benign tumors that can arise from Schwann cells, ganglion cells, and neuronal or fibrous tissues. Due to their origin from the sympathetic neural crest...

    Authors: Patrick Kirchweger, Helwig Valentin Wundsam, Ines Fischer, Christiane Sophie Rösch, Gernot Böhm, Oleksiy Tsybrovskyy, Vedat Alibegovic and Reinhold Függer

    Citation: World Journal of Surgical Oncology 2020 18:248

    Content type: Case report

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  8. Closure of large skin-soft tissue defects following soft tissue sarcoma (STS) resection has been a great challenge. The objective of this study was to evaluate the effectiveness of a novel, simple, and cheap s...

    Authors: Qiang Wu, Zengwu Shao, Yubin Li, Saroj Rai, Min Cui, Ying Yang and Baichuan Wang

    Citation: World Journal of Surgical Oncology 2020 18:247

    Content type: Research

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  9. At present, amputation was widely adopted for young patients when limb salvage was deemed risky with several surgical strategy such as rotationplasty. However, leg length discrepancies and unfavorable cosmetic...

    Authors: Zhiqiang Zhao, Qinglin Jin, Xianbiao Xie, Yongqian Wang, Tiao Lin, Junqiang Yin, Gang Huang, Changye Zou and Jingnan Shen

    Citation: World Journal of Surgical Oncology 2020 18:246

    Content type: Research

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  10. Tubal choriocarcinoma is an extremely rare but highly malignant trophoblastic tumor, which may be either gestational or non-gestational in origin. Due to atypical clinical manifestations and symptoms similar t...

    Authors: Shengjie Xu, Xiaohong Song, Chengjuan Jin and Yanli Li

    Citation: World Journal of Surgical Oncology 2020 18:245

    Content type: Case report

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  11. Postoperative atrial fibrillation (POAF) is one of the most common complications of esophagectomy, which may extend the inpatient hospital stay. Minimally invasive esophagectomy (MIE) has been increasingly use...

    Authors: Laite Chen, Lu Zhang, Lu Shi, Guosheng Fu and Chenyang Jiang

    Citation: World Journal of Surgical Oncology 2020 18:244

    Content type: Research

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  12. To compare the efficacy of three types of palliative therapy for advanced hepatocellular carcinoma (HCC), including transarterial chemoembolisation (TACE) monotherapy, sorafenib alone and their combination.

    Authors: Zhoujing Cheng, Lin He, Yingjie Guo, Yuhua Song, Shasha Song and Lijiu Zhang

    Citation: World Journal of Surgical Oncology 2020 18:243

    Content type: Research

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  13. Neoadjuvant chemotherapy is the standard front-line treatment modality in locally advanced breast cancer. Achieving pathological complete response (pCR) is a significant prognostic factor for prolonged disease...

    Authors: Ozkan Alan, Tugba Akin Telli, Bilge Aktas, Sinan Koca, Ilker Nihat Ökten, Rahib Hasanov, Tugba Basoglu, Rukiye Arikan, Nazim Can Demircan, Ozlem Ercelep, Serap Kaya, Mustafa Umit Ugurlu, Handan Kaya, Nalan Akgul Babacan, Faysal Dane and Perran Fulden Yumuk

    Citation: World Journal of Surgical Oncology 2020 18:242

    Content type: Research

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  14. The role of hypoxia-inducible factor-1α (HIF-1α) in primary colorectal cancer (CRC) and colorectal liver metastasis (CRLM) has remained unclear. The aim of this study was to investigate HIF-1α expression and i...

    Authors: Yuma Wada, Yuji Morine, Satoru Imura, Tetsuya Ikemoto, Yu Saito, Chie Takasu, Shinichiro Yamada and Mitsuo Shimada

    Citation: World Journal of Surgical Oncology 2020 18:241

    Content type: Research

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  15. Thyroid cancer (TC) is the most common endocrine malignancy; basigin (also known as BSG) plays a crucial role in tumor cell invasion, metastasis, and angiogenesis. This study was designed to identify the chang...

    Authors: Wan-Ping Guo, Deng Tang, Yu-Yan Pang, Xiao-Jiao Li, Gang Chen, Zhi-Guang Huang, Xiao-Zhun Tang, Qin-Qiao Lai, Jin-Yan Gan, Xiao-Li Huang, Xiao-Fan Liu, Zhi-Xiao Wei and Wei Ma

    Citation: World Journal of Surgical Oncology 2020 18:240

    Content type: Research

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  16. This study was designed to evaluate the effect of preoperative jaundice on long-term prognosis of gallbladder carcinoma (GBC) after radical resection (R0).

    Authors: Xin-wei Yang, Jun-yi Chen, Zhi-jian Wen, Yu-long Li, Fei-yu Wang, Liang Li, Jue Yang, Ping-hua Yang, Bao-hua Zhang and Feng Shen

    Citation: World Journal of Surgical Oncology 2020 18:239

    Content type: Research

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  17. Pancreatic cancer composed of acinar cell carcinoma (ACC) and ductal adenocarcinoma (DAC) is rare, and the clinicopathological characteristics of ACC with DAC have yet to be elucidated. Herein, we report a cas...

    Authors: Toshihisa Kimura, Shinsuke Tabata, Tamotsu Togawa, Hidetoshi Onchi, Atsushi Iida, Yasunori Sato and Takanori Goi

    Citation: World Journal of Surgical Oncology 2020 18:238

    Content type: Case report

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  18. Resection of colorectal liver metastases (CLM) has been established as the standard of care. This study aims to compare the change in clinicopathological characteristics of patients who underwent curative rese...

    Authors: Lionel Chen, Nicholas L. Syn, Brian K. P. Goh, Peng Chung Cheow, Prema Raj, Yexin Koh, Alexander Chung, Ser Yee Lee, London Lucien Ooi, Chung Yip Chan and Jin Yao Teo

    Citation: World Journal of Surgical Oncology 2020 18:237

    Content type: Research

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  19. Several randomized controlled trials (RCTs) have compared the treatment of acute lung injury (ALI) with omega-3 fatty, yet the results remained inconsistent. Therefore, we attempted this meta-analysis to analy...

    Authors: Zhongjie Huang, Jianming Zheng, Wencheng Huang, Meihao Yan, Liyue Hong, Yuancheng Hong, Runnv Jin, Xincheng Huang, Hongtao Fan, Huiling Chen, Heping Yang, Weiping Su and Xiaoping Huang

    Citation: World Journal of Surgical Oncology 2020 18:235

    Content type: Research

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  20. Pelvic exenteration (PE) may be associated with prolonged overall survival (OS) in selected patients with advanced or recurrent cervical cancer. However, the factors related to improved survival following PE a...

    Authors: Agnieszka Lewandowska, Sebastian Szubert, Krzysztof Koper, Agnieszka Koper, Grzegorz Cwynar and Lukasz Wicherek

    Citation: World Journal of Surgical Oncology 2020 18:234

    Content type: Research

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  21. The issue of whether or not splenic hilum lymph nodes (SHLN) should be excised in radical gastrectomy with D2 lymph node dissection remains controversial. In this study, we identified the clinicopathological f...

    Authors: Jun Du, Yangchao Shen, Wenwu Yan and Jinguo Wang

    Citation: World Journal of Surgical Oncology 2020 18:233

    Content type: Research

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  22. Neoadjuvant therapy can shrink tumors, increase anus preservation rate, and protect anal function. Radical surgery need cut off the diseased bowel, clean up the lymph nodes, and then restore bowel function. It...

    Authors: Guo-hua Zhao, Li Deng, Dong-man Ye, Wen-hui Wang, Yan Yan and Tao Yu

    Citation: World Journal of Surgical Oncology 2020 18:232

    Content type: Research

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  23. There have been very few reports of patients with early gastric cancer (EGC) and colorectal cancer combined with gastric gastrointestinal stromal tumors (GISTs).

    Authors: Sung Chul Lee, Kwangwoo Nam, Dajeong Nam, Min A Kwon and Dong-Wook Kim

    Citation: World Journal of Surgical Oncology 2020 18:231

    Content type: Case report

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  24. The clinical significance of pre-sarcopenia in colorectal cancer obstruction has not yet been described. The present study aimed to determine the short- and long-term oncologic impacts of pre-sarcopenia in obs...

    Authors: Chul Seung Lee, Daeyoun David Won, Soon Nam Oh, Yoon Suk Lee, In Kyu Lee, In-Ho Kim, Moon Hyung Choi and Seong Taek Oh

    Citation: World Journal of Surgical Oncology 2020 18:230

    Content type: Research

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  25. Synchronous metastatic para-aortic lymph node (mPALN) dissectionin colorectal cancer has relatively good oncological outcomes, though many patients develop recurrence. Universal prognostic factor remain unclea...

    Authors: Hajime Ushigome, Masayoshi Yasui, Masayuki Ohue, Naoaki Haraguchi, Junichi Nishimura, Keijirou Sugimura, Kazuyoshi Yamamoto, Hiroshi Wada, Hidenori Takahashi, Takeshi Omori, Hiroshi Miyata and Shuji Takiguchi

    Citation: World Journal of Surgical Oncology 2020 18:229

    Content type: Research

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  26. Chordoma of the spine is a low-grade malignant tumor with vague and indolent symptoms; thus, large tumor mass is encountered at the time of diagnosis in almost cases and makes it difficult for en-bloc free-mar...

    Authors: Pongsthorn Chanplakorn, Thamrong Lertudomphonwanit, Wittawat Homcharoen, Prakrit Suwanpramote and Wichien Laohacharoensombat

    Citation: World Journal of Surgical Oncology 2020 18:228

    Content type: Research

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  27. Myxoid liposarcoma is well known to have an unusual proclivity for extrapulmonary metastasis. However, cardiac metastasis of myxoid liposarcoma is very rare, even in patients with advanced disease.

    Authors: Kunihiro Ikuta, Tomohisa Sakai, Hiroshi Koike, Tohru Okada, Shiro Imagama and Yoshihiro Nishida

    Citation: World Journal of Surgical Oncology 2020 18:227

    Content type: Case report

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  28. Current researches have revealed that delta-like protein 3 (DLL3) may be related with prognosis in patients with small cell lung cancer (SCLC). However, this finding remains controversial in small cell lung ca...

    Authors: Benchao Chen, Heng Li, Chao Liu, Shuting Wang, Feiyue Zhang, Li Zhang, Mingjie Li and Gaofeng Li

    Citation: World Journal of Surgical Oncology 2020 18:226

    Content type: Research

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  29. The cell proliferative markers are very important in breast cancer. Since SPAG5 and NuMA proteins play a significant role in the mitosis regulatory network and cell division, we aimed to study their mRNA level...

    Authors: Zeinab Mohamadalizadeh-Hanjani, Shirin Shahbazi and Loabat Geranpayeh

    Citation: World Journal of Surgical Oncology 2020 18:225

    Content type: Research

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  30. It is well established that retrieved lymph node (RLN) counts were positively correlated with better overall survival in gastric cancer (GC). But little is known about the relationship between RLN count and sh...

    Authors: Feng Sun, Song Liu, Peng Song, Chen Zhang, Zhijian Liu, Wenxian Guan and Meng Wang

    Citation: World Journal of Surgical Oncology 2020 18:224

    Content type: Research

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  31. Three-dimensional (3D) computed tomography (CT) reconstruction technology has gained attention owing to its potential in locating ground glass nodules in the lung. The 3D printing technology additionally allow...

    Authors: Yangming Chen, Jiguang Zhang, Qianshun Chen, Tian Li, Kai Chen, Qinghua Yu and Xing Lin

    Citation: World Journal of Surgical Oncology 2020 18:223

    Content type: Research

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  32. Although RNA-binding proteins play an essential role in a variety of different tumours, there are still limited efforts made to systematically analyse the role of RNA-binding proteins (RBPs) in the survival of...

    Authors: Xuehui Fan, Lili Liu, Yue Shi, Fanghan Guo, Haining Wang, Xiuli Zhao, Di Zhong and Guozhong Li

    Citation: World Journal of Surgical Oncology 2020 18:222

    Content type: Research

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  33. Sarcopenia is a prognostic factor in various cancers. However, the impact of sarcopenia in patients with recurrent pancreatic cancer remains unclear. This study evaluated the prognostic significance of sarcope...

    Authors: Teruhisa Sakamoto, Takuki Yagyu, Ei Uchinaka, Kozo Miyatani, Takehiko Hanaki, Kyoichi Kihara, Tomoyuki Matsunaga, Manabu Yamamoto, Naruo Tokuyasu, Soichiro Honjo and Yoshiyuki Fujiwara

    Citation: World Journal of Surgical Oncology 2020 18:221

    Content type: Research

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  34. Hepatocellular carcinoma (HCC) is the most common malignant tumor of the liver, and its morbidity and mortality have been increasing in recent years. The early diagnosis and prompt treatment of small HCC are c...

    Authors: Xue-Qin Li, Xing Wang, Da-Wei Zhao, Jun Sun, Jiao-Jiao Liu, Dong-Dong Lin, Guang Yang, Hui Liu, Zhen-Ying Xia, Cui-Yu Jia and Hong-Jun Li

    Citation: World Journal of Surgical Oncology 2020 18:219

    Content type: Review

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  35. Adenocarcinoma of the pancreatic body and tail is associated with a dismal prognosis. As patients frequently present themselves with locally advanced tumors, extended surgery including multivisceral resection ...

    Authors: Oliver Beetz, Akin Sarisin, Alexander Kaltenborn, Jürgen Klempnauer, Michael Winkler and Gerrit Grannas

    Citation: World Journal of Surgical Oncology 2020 18:218

    Content type: Research

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  36. Transurethral resection of the bladder tumour (TUR) is associated with a risk of bladder perforation. The underlying mechanisms and risk factors are not fully understood. The aim of this study was to determine...

    Authors: Sławomir Poletajew, Tomasz Ilczuk, Wojciech Krajewski, Grzegorz Niemczyk, Agata Cyran, Łukasz Białek, Piotr Radziszewski, Barbara Górnicka and Piotr Kryst

    Citation: World Journal of Surgical Oncology 2020 18:216

    Content type: Research

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  37. Natural orifice specimen extraction surgery is a novel technique of minimally invasive surgery. The purpose of this study was to compare the safety of laparoscopic anterior resection with natural orifice speci...

    Authors: Jun He, Hai-Bo Yao, Chang-Jian Wang, Qin-Yan Yang, Jian-Ming Qiu, Jin-Ming Chen, Zhong Shen and Guan-Gen Yang

    Citation: World Journal of Surgical Oncology 2020 18:215

    Content type: Research

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  38. Recently, a novel surgical procedure, named as laparoscopic proximal gastrectomy (LPG) with double-tract reconstruction (DTR), has been reported to provide surgical benefits in the treatment of proximal early ...

    Authors: Yixin Xu, Jie Gao, Yibo Wang, Yulin Tan, Cheng Xi, Nianyuan Ye, Dapeng Wu and Xuezhong Xu

    Citation: World Journal of Surgical Oncology 2020 18:214

    Content type: Review

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  39. Lymph node staging of ductal adenocarcinoma of the pancreatic head (PDAC) by cross-sectional imaging is limited. The aim of this study was to determine the diagnostic accuracy of expanded criteria in nodal sta...

    Authors: Florian N. Loch, Patrick Asbach, Matthias Haas, Hendrik Seeliger, Katharina Beyer, Christian Schineis, Claudius E. Degro, Georgios A. Margonis, Martin E. Kreis and Carsten Kamphues

    Citation: World Journal of Surgical Oncology 2020 18:213

    Content type: Research

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  40. Laparoscopic tumor-specific mesorectal excision (TSME) preserving the left colic artery and superior rectal artery is still a technically challenging procedure. We conducted this study to demonstrate the feasi...

    Authors: Chi Zhang, Hao-tang Wei, Wenqing Hu, Yueming Sun, Qinyuan Zhang, Masanobu Abe, Zhuoran Du, Yingying Xu, Liang Zong and Xiang Hu

    Citation: World Journal of Surgical Oncology 2020 18:212

    Content type: Research

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  41. Cowden’s syndrome is an autosomal dominant disease with variable penetrance, involving the tumor suppressor phosphatase and tension homolog gene, located on chromosome 10q22-23, responsible for cell proliferat...

    Authors: Sofia Miguelote, Roberto Silva, J. L. Fougo, L. E. Barbosa and J. P. Araújo Teixeira

    Citation: World Journal of Surgical Oncology 2020 18:211

    Content type: Case report

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  42. Ischemia–reperfusion injury is harmful in partial nephrectomy (PN) in renal cell carcinoma. Choosing an appropriate surgical method is important to reduce ischemia–reperfusion injury. This study aimed to compa...

    Authors: Jinhong Xu, Shuxiong Xu, Biao Yao, Run Xu, Yuangao Xu, Fa Sun, Qian Qiu and Hua Shi

    Citation: World Journal of Surgical Oncology 2020 18:210

    Content type: Research

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  43. Angiopoietin-Tie2 and nitric oxide pathway is crucial in tumor angiogenesis and closely correlates with tumor development, growth, and metastasis. This study aimed to investigate the angiopoietin-Tie2 and nitr...

    Authors: Hsiang-Ling Wu, You-Hsiang Chu, Ying-Hsuan Tai, Mei-Yung Tsou, Cheng-Hsien Wu, Wen-Liang Lo, Shyh-Kuan Tai, Chun-Chang Yeh and Chih-Cherng Lu

    Citation: World Journal of Surgical Oncology 2020 18:209

    Content type: Research

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  44. Pancreatic neuroendocrine tumors (PNET) are rare, with a significant malignant potential. This study aimed to determine outcomes of patients with resected PNETs according to the cystic component and confirm th...

    Authors: Ange Khalil, Jacques Ewald, Ugo Marchese, Aurélie Autret, Jonathan Garnier, Patricia Niccoli, Gilles Piana, Flora Poizat, Marc Giovannini, Jean-Robert Delpero and Olivier Turrini

    Citation: World Journal of Surgical Oncology 2020 18:208

    Content type: Research

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  45. The role of renal artery embolization (RAE) in the therapeutic armamentarium is always controversial. The present study aimed to assess the safety and the surgical outcomes of the instant renal artery emboliza...

    Authors: Guangxin Tang, Xiaoxu Chen, Jianwei Wang, Wei He and Zhihong Niu

    Citation: World Journal of Surgical Oncology 2020 18:206

    Content type: Research

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  46. Anastomotic leakage (AL) significantly impairs short-term outcomes. The impact on the long-term outcomes remains unclear. This study aimed to identify the risk factors for AL and the impact on long-term surviv...

    Authors: Marius Kryzauskas, Augustinas Bausys, Austeja Elzbieta Degutyte, Vilius Abeciunas, Eligijus Poskus, Rimantas Bausys, Audrius Dulskas, Kestutis Strupas and Tomas Poskus

    Citation: World Journal of Surgical Oncology 2020 18:205

    Content type: Research

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