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  1. Currently, nivolumab and ipilimumab are the most widely used immune checkpoint inhibitors. We performed a meta-analysis to evaluate the efficacy and treatment-related adverse events (TRAEs) of nivolumab plus i...

    Authors: Jingjie Chen, Shengnan Li, Qigu Yao, Nannan Du, Xiaojun Fu, Yuanmei Lou, Mengru Wang, Feiyan Mao, Danyi Mao, Parikshit Asutosh Khadaroo and Yingying Tang

    Citation: World Journal of Surgical Oncology 2020 18:150

    Content type: Review

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  2. The purpose of this study was to compare clinicopathological features of patients with non-schistosomal and schistosomal colorectal cancer to explore the effect of schistosomiasis on colorectal cancer (CRC) pa...

    Authors: Weixia Wang, Kui Lu, Limei Wang, Hongyan Jing, Weiyu Pan, Sinian Huang, Yanchao Xu, Dacheng Bu, Meihong Cheng, Jing Liu, Jican Liu, Weidong Shen, Yingyi Zhang, Junxia Yao and Ting Zhu

    Citation: World Journal of Surgical Oncology 2020 18:149

    Content type: Research

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  3. The retroperitoneal robotic assisted partial nephrectomy (RAPN) is suitable for tumors locating on the posterior side of the kidney. However, the posterior hilar tumor poses an additional surgical challenge du...

    Authors: Xiaotao Yin, Sinan Jiang, Zhiqiang Shao, Yongliang Lu, Jiaxiang Guo, Yi Xiao, Xiaoying Zhu, Hualiang Yu, Han Ma, Yu Yang and Jiangping Gao

    Citation: World Journal of Surgical Oncology 2020 18:148

    Content type: Technical innovations

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  4. Mounting evidences displayed that miRNAs play crucial roles in tumor initiation and development. However, the regulation and relevant mechanism of miR-1825 in glioblastoma (GBM) remain unclear.

    Authors: Fengqin Lu, Chunhong Li, Yuping Sun, Ting Jia, Na Li and Haiyan Li

    Citation: World Journal of Surgical Oncology 2020 18:147

    Content type: Research

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  5. Colon adenocarcinoma (COAD) is a gastrointestinal tumor with a high degree of malignancy. Its deterioration process is closely related to the tumor microenvironment, and transcription factors (TF) play a regul...

    Authors: Sihan Chen, G. D. Cao, Wu Wei, Lu Yida, He Xiaobo, Yang Lei, Chen Ke, Bo Chen and Mao Ming Xiong

    Citation: World Journal of Surgical Oncology 2020 18:146

    Content type: Research

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  6. The incidence of thyroid cancer is increasing worldwide. This study investigated the association of B-type RAF kinase (BRAF)V600E mutation status, the expression of BRAF-activated long non-coding RNA (BANCR) and ...

    Authors: Chenlei Shi, Jia Cao, Tiefeng Shi, Meihua Liang, Chao Ding, Yichen Lv, Weifeng Zhang, Chuanle Li, Wenchao Gao, Gang Wu and Jianting Man

    Citation: World Journal of Surgical Oncology 2020 18:145

    Content type: Research

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  7. The prognosis of adenocarcinoma of the esophagogastric junction (AEG) is poor. Understanding the postoperative recurrence pattern of AEG is helpful to verify the effectiveness of treatment and optimize subsequ...

    Authors: Haitao Xu, Lianguo Zhang, Jing Miao, Shuai Liu, Hongjian Liu, Teng Jia and Qingguang Zhang

    Citation: World Journal of Surgical Oncology 2020 18:144

    Content type: Research

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  8. The postoperative survival rate of patients with esophageal squamous cell carcinoma (ESCC) remains poor compared with other gastrointestinal cancers. We hypothesized that skeletal muscle loss in the postoperat...

    Authors: Naoaki Maeda, Yasuhiro Shirakawa, Shunsuke Tanabe, Kazufumi Sakurama, Kazuhiro Noma and Toshiyoshi Fujiwara

    Citation: World Journal of Surgical Oncology 2020 18:143

    Content type: Research

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  9. The GOD VISION wireless smart glass-shaped monitor (INBYTE) was used in the treatment of an elderly patient with mixed breathing disorder undergoing transanal minimally invasive surgery (TAMIS) for low rectal ...

    Authors: Nobuhisa Matsuhashi, Yoshinori Iwata, Mana Kawajiri, Takao Takahashi, Shigeru Kiyama, Shunya Kiriyama, Machi Uehara, Takeharu Imai, Hisashi Imai, Yoshihiro Tanaka, Naoki Okumura and Kazuhiro Yoshida

    Citation: World Journal of Surgical Oncology 2020 18:141

    Content type: Case report

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  10. Associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) and two stage hepatectomy with inter-stage portal vein embolization (TSH/PVE) are surgical maneuvers applied in patients with...

    Authors: Jan Bednarsch, Zoltan Czigany, Samara Sharmeen, Gregory van der Kroft, Pavel Strnad, Tom Florian Ulmer, Peter Isfort, Philipp Bruners, Georg Lurje and Ulf Peter Neumann

    Citation: World Journal of Surgical Oncology 2020 18:140

    Content type: Research

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  11. Conversion chemotherapy may downsize unresectable colorectal liver metastases (CRLMs), but may cause liver injury and splenic enlargement. The effect of preoperative chemotherapy on liver regeneration after li...

    Authors: Takanori Konishi, Hiroyuki Yoshidome, Hiroaki Shimizu, Hideyuki Yoshitomi, Katsunori Furukawa, Tsukasa Takayashiki, Satoshi Kuboki, Shigetsugu Takano, Masaru Miyazaki and Masayuki Ohtsuka

    Citation: World Journal of Surgical Oncology 2020 18:139

    Content type: Research

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  12. Prognosis for patients with advanced hepatocellular carcinoma with a tumor thrombus in the inferior vena cava or right atrium is extremely poor due to cancer progression, pulmonary embolism, and congestion of ...

    Authors: Koichi Tomita, Motohide Shimazu, Kiminori Takano, Takahiro Gunji, Yosuke Ozawa, Toru Sano, Naokazu Chiba, Yuta Abe and Shigeyuki Kawachi

    Citation: World Journal of Surgical Oncology 2020 18:138

    Content type: Case report

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  13. The clinical relevance of pancreatic intraepithelial neoplasia (PanIN) at the resection margin of pancreatic ductal adenocarcinoma remains unknown. We aimed to investigate its clinical impact at the pancreatic...

    Authors: Tsengelmaa Jamiyan, Takayuki Shiraki, Yoshihiro Kurata, Masanori Ichinose, Keiichi Kubota and Yasuo Imai

    Citation: World Journal of Surgical Oncology 2020 18:137

    Content type: Research

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  14. Leukocyte-associated immunoglobulin-like receptor-1 (LAIR-1) is a collagen receptor belonging to the immunoglobulin superfamily. Although previous studies have evaluated the biological role of LAIR in solid tu...

    Authors: Jinxue Zhang, Yuan Zhang, Shiyang Cheng, Yang Mu, Yongming Liu, Xin Yi, Dongxu Jiang, Yong Ding and Ran Zhuang

    Citation: World Journal of Surgical Oncology 2020 18:136

    Content type: Research

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  15. Individual prediction of life expectancy in patients with spinal metastases from hepatocellular carcinoma (HCC) is key for optimal treatment selection, especially when identifying potential candidates for surg...

    Authors: Phichayut Phinyo, Chonmavadh Boonyanaruthee, Permsak Paholpak, Dumneoensun Pruksakorn, Areerak Phanphaisarn and Apiruk Sangsin

    Citation: World Journal of Surgical Oncology 2020 18:135

    Content type: Research

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  16. Sentinel lymph node (SLN) biopsy is an attractive technique that is widely performed in many oncological surgeries. However, the potential risks in SLN biopsy for cervical cancer remains largely unclear.

    Authors: Hua Tu, Ting Wan, Xinke Zhang, Haifeng Gu, Yanling Feng, He Huang and Jihong Liu

    Citation: World Journal of Surgical Oncology 2020 18:133

    Content type: Research

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  17. Patients with locally advanced colon cancer (LACC) treated with surgery had a high risk of local recurrence. The outcomes can vary significantly among patients with pT3 disease. This study was undertaken to as...

    Authors: Li Ma, Junhao Qiang, Heliang Yin, Lin Lin, Yan Jiao, Changying Ma, Xinwei Li, Li Dong, Jinglin Cui, Dongmei Wei, Ankur M. Sharma, David L. Schwartz, Weikuan Gu and Hong Chen

    Citation: World Journal of Surgical Oncology 2020 18:132

    Content type: Research

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  18. Enhanced recovery after surgery (ERAS) protocol has been identified to be beneficial in the amount of operations such as gastrointestinal surgery. However, the efficacy and safety in robot-assisted laparoscopi...

    Authors: Yurong Zhao, Shaobo Zhang, Bianjiang Liu, Jie Li and Hanxia Hong

    Citation: World Journal of Surgical Oncology 2020 18:131

    Content type: Review

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  19. Accurate prediction of recurrence-free survival (RFS) is important for the prognosis of cutaneous melanoma patients. The image-based pathological examination remains as the gold standard for diagnosis. It is o...

    Authors: Yanbin Peng, Yunfeng Chu, Zhong Chen, Wen Zhou, Shengxiang Wan, Yingfeng Xiao, Youlong Zhang and Jialu Li

    Citation: World Journal of Surgical Oncology 2020 18:130

    Content type: Technical innovations

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  20. The survival outcomes of neoadjuvant chemotherapy (NACT) versus adjuvant chemotherapy (ACT) for patients with triple-negative breast cancer (TNBC) remain unclear. Therefore, in this study, a meta-analysis was ...

    Authors: Lin-Yu Xia, Qing-Lin Hu, Jing Zhang, Wei-Yun Xu and Xiao-Shi Li

    Citation: World Journal of Surgical Oncology 2020 18:129

    Content type: Research

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  21. Deletions of 17p13 recurrently occur in renal cell carcinoma (RCC) but their prognostic role seems to be uncertain.

    Authors: Till Eichenauer, Navid Shadanpour, Martina Kluth, Cosima Göbel, Sören Weidemann, Christoph Fraune, Franziska Büscheck, Claudia Hube-Magg, Christina Möller-Koop, Roland Dahlem, Margit Fisch, Michael Rink, Silke Riechardt, Eike Burandt, Christian Bernreuther, Sarah Minner…

    Citation: World Journal of Surgical Oncology 2020 18:128

    Content type: Research

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  22. To detect the expression level of organic anion-transporting polypeptide 1B3 (OATP1B3) in hepatocellular carcinoma (HCC) and to determine the relationship between OATP1B3 expression, clinicopathological featur...

    Authors: Shihan Chen, Kun Li, Jiayun Jiang, Xiaofei Wang, Yuelong Chai, Chang Zhang, Qingsong Deng, Ling Shuai, Kai Feng, Kuansheng Ma and Leida Zhang

    Citation: World Journal of Surgical Oncology 2020 18:127

    Content type: Research

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  23. Additional studies comparing laparoscopic gastrectomy (LG) versus open gastrectomy (OG) for advanced gastric cancer (AGC) have been published, and it is necessary to update the systematic review of this subject.

    Authors: Zhipeng Zhu, Lulu Li, Jiuhua Xu, Weipeng Ye, Junjie Zeng, Borong Chen and Zhengjie Huang

    Citation: World Journal of Surgical Oncology 2020 18:126

    Content type: Review

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  24. Gastrointestinal stromal tumors (GISTs) generally form well-defined mass lesions. However, some cases of the flatly distributed and muscularis propria-replacing GISTs have been reported so far. We experienced ...

    Authors: Yuka Shintaku, Yuya Asano, Takahiro Watanabe, Takako Kihara, Eri Ishikawa, Yuan Jiayin, Neinei Kimura, Koji Kinoshita and Seiichi Hirota

    Citation: World Journal of Surgical Oncology 2020 18:125

    Content type: Case report

    Published on:

  25. Hepatopancreaticobiliary malignancies with peritoneal carcinomatosis exhibit poor survival with current therapies: hepatocellular carcinoma 11 months with sorafenib, and pancreaticobiliary 9–14 months with sys...

    Authors: Natasha Leigh, Daniel Solomon, Eric Pletcher, Daniel M. Labow, Deepa R. Magge, Umut Sarpel and Benjamin J. Golas

    Citation: World Journal of Surgical Oncology 2020 18:124

    Content type: Research

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  26. The aim was to evaluate the prognostic factors, clinicopathological characteristics, and surgical outcomes after hepatectomy in very elderly patients with hepatocellular carcinoma (HCC).

    Authors: Shingo Shimada, Toshiya Kamiyama, Tatsuya Orimo, Akihisa Nagatsu, Yoh Asahi, Yuzuru Sakamoto, Hirofumi Kamachi and Akinobu Taketomi

    Citation: World Journal of Surgical Oncology 2020 18:122

    Content type: Research

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  27. Hepatocellular carcinoma (HCC) is the most common primary malignancy of the liver with a dismal prognosis. Vascular invasion, among others, is the most robust indicator of postoperative recurrence and overall ...

    Authors: Chao-Wei Lee, Ming-Chin Yu, Gigin Lin, Jo-Chu Chiu, Meng-Han Chiang, Chang-Mu Sung, Yi-Chung Hsieh, Tony Kuo, Cheng-Yu Lin and Hsin-I Tsai

    Citation: World Journal of Surgical Oncology 2020 18:121

    Content type: Research

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  28. Advanced age is a risk factor for colorectal cancer, and very elderly patients often need to be surgically treated. This study aimed to analyze the outcomes of a cohort of nonagenarian patients operated on for...

    Authors: Cristina Roque-Castellano, Roberto Fariña-Castro, Eva María Nogués-Ramia, Manuel Artiles-Armas and Joaquín Marchena-Gómez

    Citation: World Journal of Surgical Oncology 2020 18:120

    Content type: Research

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  29. It is still controversial whether hepatocellular carcinoma (HCC) patients with lymph node invasion should receive surgery treatment. This study aimed to evaluate the efficacy of surgery (liver resection and lo...

    Authors: Lei Chen, Tao Sun, Shi Chen, Yanqiao Ren, Fan Yang and Chuansheng Zheng

    Citation: World Journal of Surgical Oncology 2020 18:119

    Content type: Research

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  30. Preventing breast cancer-related lymphedema (BCRL) by preserving upper lymphatic drainage is still controversial. Our study aimed to use the axillary reverse mapping (ARM) technique in patients who underwent a...

    Authors: Siyao Liu, Nan Wang, Ping Gao, Peng Liu, Houpu Yang, Fei Xie, Siyuan Wang, Miao Liu and Shu Wang

    Citation: World Journal of Surgical Oncology 2020 18:118

    Content type: Research

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  31. More than one third of breast cancer patients including those that are diagnosed in early stages will develop distant metastasis. Patterns of distant metastasis and the associated risks according to the molecu...

    Authors: Sumadi Lukman Anwar, Widya Surya Avanti, Andreas Cahyo Nugroho, Lina Choridah, Ery Kus Dwianingsih, Wirsma Arif Harahap, Teguh Aryandono and Wahyu Wulaningsih

    Citation: World Journal of Surgical Oncology 2020 18:117

    Content type: Research

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  32. Neuron-specific enolase (NSE) has become a widely used and easily attainable laboratory assay of small cell lung cancer (SCLC). However, the prognostic value of NSE for SCLC patients remains controversial. The...

    Authors: Zhoujunyi Tian, Chaoyang Liang, Zhenrong Zhang, Huanshun Wen, Hongxiang Feng, Qianli Ma, Deruo Liu and Guangliang Qiang

    Citation: World Journal of Surgical Oncology 2020 18:116

    Content type: Research

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  33. MiR-125 has been shown to be involved in a variety of cancers, including cervical cancer (CC). Here, our goal was to explore miR-125 functional role and molecular mechanism in cervical cancer development and p...

    Authors: Ke Fu, Ling Zhang, Rui Liu, Qi Shi, Xue Li and Min Wang

    Citation: World Journal of Surgical Oncology 2020 18:115

    Content type: Research

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  34. This study aims to identify predictive local recurrence risk factors and site-specific local recurrence pattern of upper tract urothelial carcinoma (UTUC) with different primary tumor locations.

    Authors: Xiaoying Li, Ming Cui, Xiaobin Gu, Dong Fang, Hongzhen Li, Shangbin Qin, Kunlin Yang, Tianzhao Zhu, Xuesong Li, Liqun Zhou, Xian-Shu Gao and Dian Wang

    Citation: World Journal of Surgical Oncology 2020 18:114

    Content type: Research

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  35. Hepatocellular carcinoma (HCC) is still a major health burden in China considering its high incidence and mortality. Long non-coding RNAs (lncRNAs) were found playing vital roles in tumor progression, suggesti...

    Authors: Fenfen Hong, Yu Gao, Yang Li, Linfeng Zheng, Feng Xu and Xianpeng Li

    Citation: World Journal of Surgical Oncology 2020 18:113

    Content type: Research

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  36. Preoperative clinical diagnosis of lymph node (LN) metastasis and subsequent pathological diagnosis are often not in agreement. Detection of false-negative LNs is essential in selecting an optimal treatment st...

    Authors: Akiyuki Wakita, Satoru Motoyama, Yusuke Sato, Yuta Kawakita, Yushi Nagaki, Kaori Terata, Kazuhiro Imai and Yoshihiro Minamiya

    Citation: World Journal of Surgical Oncology 2020 18:111

    Content type: Research

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  37. During esophagectomy for esophageal cancer, a gastric tube is necessary for the perioperative period. However, the gastric tube and anastomotic anvil placement is often extremely difficult and time consuming d...

    Authors: Yi Shen, Yunfeng Zhou and Xiang Zhuang

    Citation: World Journal of Surgical Oncology 2020 18:110

    Content type: Technical innovations

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  38. The most common sites of recurrence after liver transplantation for hepatocellular carcinoma (HCC) have been reported to be the liver, lung, bone, and adrenal glands, but there have also been many reports of c...

    Authors: Taiji Tohyama, Katsunori Sakamoto, Kei Tamura, Taro Nakamura, Jota Watanabe, Hiroyuki Wakisaka and Yasutsugu Takada

    Citation: World Journal of Surgical Oncology 2020 18:109

    Content type: Case report

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  39. Pituicytoma is a rare pituitary non-neuroendocrine tumour. The awareness of pituitary non-neuroendocrine tumours has gradually increased over the past several decades, but the knowledge of some histological va...

    Authors: Youde Cao, Yan Zeng, Xue Qin, Yiwen Tan, Min Zeng, Lijuan Wang, Xiaojing Cao, Lingfeng Zou and Chenglong Wang

    Citation: World Journal of Surgical Oncology 2020 18:108

    Content type: Case report

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  40. Surgery for colorectal cancer (CRC) is increasingly being performed via the minimally invasive route. However, reports of postoperative wound and port site seeding as well as peritoneal spillage have been worr...

    Authors: Peter C. Ambe, Joseph Kankam and Konstantinos Zarras

    Citation: World Journal of Surgical Oncology 2020 18:107

    Content type: Research

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  41. The benefit of surgery in patients with non-colorectal non-neuroendocrine liver metastases (NCRNNELM) remains controversial. At the population level, several statistical prognostic factors and scores have been...

    Authors: Ali Bohlok, Valerio Lucidi, Fikri Bouazza, Ali Daher, Desislava Germanova, Jean Luc Van Laethem, Alain Hendlisz and Vincent Donckier

    Citation: World Journal of Surgical Oncology 2020 18:106

    Content type: Research

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  42. Sarcomatoid carcinoma of the pancreas (SCP) tends to have similar or even worse prognosis than that of conventional pancreatic ductal adenocarcinoma. The clinical and pathological features of SCP remain poorly...

    Authors: Toshihisa Kimura, Daisuke Fujimoto, Tamotsu Togawa, Makoto Ishida, Atsushi Iida, Yasunori Sato and Takanori Goi

    Citation: World Journal of Surgical Oncology 2020 18:105

    Content type: Case report

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  43. Selecting the treatment procedure for cancer patients is a challenging task. We report our initial experience of complete laparoscopic radical nephroureterectomy (RNU) for patients with upper urinary tract uro...

    Authors: Makito Miyake, Nobutaka Nishimura, Katsuya Aoki, Chihiro Ohmori, Takuto Shimizu, Takuya Owari, Shunta Hori, Yosuke Morizawa, Daisuke Gotoh, Yasushi Nakai, Satoshi Anai, Kazumasa Torimoto, Nobumichi Tanaka and Kiyohide Fujimoto

    Citation: World Journal of Surgical Oncology 2020 18:104

    Content type: Technical innovations

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  44. Malposition of the intercostal space used for single-port thoracoscopy surgery can lead to problems. This study was to assess the accuracy of point-of-care ultrasound in verifying the position of intercostal s...

    Authors: Chenxi Li, Jianjun Wang, Zeheng Ma, Bing Li, Kang Kang, Li Wei and Wei Zhang

    Citation: World Journal of Surgical Oncology 2020 18:103

    Content type: Research

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  45. Gastric carcinoma with lymphoid stroma (GCLS) is a rare subtype of gastric cancer. There have been several reports demonstrating the favorable prognosis of early GCLS without lymph node metastasis (LNM) compar...

    Authors: Kenichi Iwasaki, Takeshi Suda, Yuki Takano, Yuki Ohno, Erika Yamada, Naoto Okazaki, Kosuke Takahashi, Takafumi Watanabe, Yosuke Makuuchi, Yoshihiro Ota, Yoshiaki Osaka, Akiyoshi Seshimo, Kenji Katsumata and Akihiko Tsuchida

    Citation: World Journal of Surgical Oncology 2020 18:102

    Content type: Research

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  46. When endometrial carcinoma invades the cervical stroma, overall survival and disease-free survival decrease. However, it is still controversial whether patients in suspected stage II should be treated with rad...

    Authors: Salim Abraham Barquet-Muñoz, David Cantú-de-León, Antonio Bandala-Jacques, Aarón González-Enciso, David Isla-Ortiz, Diddier Prada, Luis A. Herrera and R. A. Salcedo-Hernández

    Citation: World Journal of Surgical Oncology 2020 18:101

    Content type: Research

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