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  1. Pancreatic adenocarcinoma (PAAD) is a nonimmunogenic tumor, and very little is known about the relationship between the host immune response and patient survival. We aimed to develop an immune prognostic model...

    Authors: Xiaoqiang Gu, Qiqi Zhang, Xueying Wu, Yue Fan and Jianxin Qian

    Citation: World Journal of Surgical Oncology 2021 19:112

    Content type: Research

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  2. Ezrin-radixin-moesin (ERM) have been explored in many cancer processes. Moesin, as its component, has also been found to play an important role in the prognosis of cancer patients, tumor metastasis, drug resis...

    Authors: Yan-Qi Li, Zhi Zheng, Quan-Xing Liu, Xiao Lu, Dong Zhou, Jiao Zhang, Hong Zheng and Ji-Gang Dai

    Citation: World Journal of Surgical Oncology 2021 19:109

    Content type: Research

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  3. Mastoscopic surgery is proven to have lower incidence of postoperative complications and better postoperative recovery than traditional breast cancer surgery. This study aimed to examine the feasibility of mas...

    Authors: Jiaqi Liu, Heshan Yu, Yuxiao He, Ting Yan, Yu Ding, Jun Chu, Ning Gao, Xiaona Lin, Yanbin Xu and Guijin He

    Citation: World Journal of Surgical Oncology 2021 19:108

    Content type: Research

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  4. Frailty has been shown to be a good predictor of post-operative complications and death in patients undergoing gastrointestinal surgery. The aim of this study was to analyze the differences between frail and n...

    Authors: Manuel Artiles-Armas, Cristina Roque-Castellano, Roberto Fariña-Castro, Alicia Conde-Martel, María Asunción Acosta-Mérida and Joaquín Marchena-Gómez

    Citation: World Journal of Surgical Oncology 2021 19:106

    Content type: Research

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  5. A pathological complete response (pCR) after neoadjuvant chemoradiotherapy (NACRT) ensures long-term survival in esophageal squamous cell carcinoma (ESCC) patients following esophagectomy, but pCR patients are...

    Authors: Yushi Nagaki, Satoru Motoyama, Yusuke Sato, Akiyuki Wakita, Hiromu Fujita, Yoshihiro Sasaki, Kazuhiro Imai and Yoshihiro Minamiya

    Citation: World Journal of Surgical Oncology 2021 19:105

    Content type: Research

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  6. Colon cancer is a commonly worldwide cancer with high morbidity and mortality. Long non-coding RNAs (lncRNAs) are involved in many biological processes and are closely related to the occurrence of colon cancer...

    Authors: Meihong Gao, Yang Guo, Yifu Xiao and Xuequn Shang

    Citation: World Journal of Surgical Oncology 2021 19:104

    Content type: Research

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  7. As LEEP (loop electrosurgical excision procedure) is being increasingly used for the diagnosis and treatment of uterine cervical intraepithelial neoplasia, surgical smoke during LEEP has become an inevitable h...

    Authors: Yi Liu, Menghuang Zhao, Yongqiang Shao, Linzhi Yan and Xueqiong Zhu

    Citation: World Journal of Surgical Oncology 2021 19:103

    Content type: Research

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  8. Laparoscopic surgery has been widely accepted to treat early-stage gastric cancer. However, it is still controversial to perform laparoscopic gastrectomy plus D2 lymphadenectomy for locally advanced gastric ca...

    Authors: Yawei Wang, Yan Wang, Wang Wu, Xiaofang Lu, Tailai An and Jiling Jiang

    Citation: World Journal of Surgical Oncology 2021 19:102

    Content type: Research

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  9. Laparoscopic gastrectomy is an acceptable procedure for early-stage gastric cancer; however, most patients are diagnosed at an advanced stage and older age in Taiwan. The feasibility and safety of applying lap...

    Authors: Si-Yuan Wu, Meng-Hsing Ho, Hao-Ming Chang, Kuo-Feng Hsu, Jyh-Cherng Yu and De-Chuan Chan

    Citation: World Journal of Surgical Oncology 2021 19:101

    Content type: Research

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  10. Down syndrome critical region 1 (DSCR1) is associated with carcinogenesis and tumor growth in several types of malignancy. However, little is known about the role of DSCR1 in CRC progression. The present study...

    Authors: Wen-Xiang Li, Jia-Jia Zheng, Gang Zhao, Chen-Tao LYU and Wei-Qi Lu

    Citation: World Journal of Surgical Oncology 2021 19:100

    Content type: Research

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  11. The American Society of Colon and Rectal Surgeons is suggesting laparoscopic surgeries for colorectal cancer. Conventional perioperative procedures like long preoperative fasting and bowel procedures are not u...

    Authors: Baoxin Wang, Zhenming Wu, Rui Zhang, Yue Chen, Jiuxing Dong and Xiuheng Qi

    Citation: World Journal of Surgical Oncology 2021 19:99

    Content type: Research

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  12. With the development of medical technology, credible options for defect reconstructions after the resection of benign bone tumors of the lower extremities have become a high priority. As the current reconstruc...

    Authors: Lei Wang, Dinghao Luo, Junxiang Wu, Kai Xie, Yu Guo, Yaokai Gan, Wen Wu and Yongqiang Hao

    Citation: World Journal of Surgical Oncology 2021 19:98

    Content type: Research

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  13. Hepatectomy for resectable colorectal liver metastasis (CRLM) is recommended. However, the efficacy of upfront hepatectomy without neoadjuvant chemotherapy (NAC) is unclear due to the uncertainty of perioperat...

    Authors: Kosuke Ono, Tomoyuki Abe, Akihiko Oshita, Yusuke Sumi, Takuya Yano, Hiroshi Okuda, Manabu Kurayoshi, Tsuyoshi Kobayashi, Hideki Ohdan, Toshio Noriyuki and Masahiro Nakahara

    Citation: World Journal of Surgical Oncology 2021 19:97

    Content type: Research

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  14. Colorectal cancer is the third most common type of cancer in the world. We characterize a cohort of patients who survived up to 5 years without recurrence and identify factors predicting the probability of cure.

    Authors: Inge van den Berg, Robert R. J. Coebergh van den Braak, Jeroen L. A. van Vugt, Jan N. M. Ijzermans and Stefan Buettner

    Citation: World Journal of Surgical Oncology 2021 19:96

    Content type: Research

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  15. The feasibility of association liver partition and portal vein ligation for staged hepatectomy (ALPPS) for solitary huge hepatocellular carcinoma (HCC, maximal diameter ≥ 10 cm) remains uncertain. This study a...

    Authors: Zhenfeng Deng, Zongrui Jin, Yonghui Qin, Mingqi Wei, Jilong Wang, Tingting Lu, Ling Zhang, Jingjing Zeng, Li Bao, Ya Guo, Minhao Peng, Banghao Xu and Zhang Wen

    Citation: World Journal of Surgical Oncology 2021 19:95

    Content type: Research

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  16. Frailty is an important consideration for older patients undergoing surgery. We aimed to investigate whether frailty could be a prognostic factor in patients with pancreatic ductal adenocarcinoma who underwent...

    Authors: Shinichiro Yamada, Mitsuo Shimada, Yuji Morine, Satoru Imura, Tetsuya Ikemoto, Yu Saito, Katsuki Miyazaki, Takuya Tokunaga and Masaaki Nishi

    Citation: World Journal of Surgical Oncology 2021 19:94

    Content type: Research

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  17. In the last decade, two research groups, the French group by Clough et al. (Br J Surg. 97:1659–65, 2010) and the Chinese one by Li et al. (ISRN Oncol 2013:279013, 2013), proposed two types of classification of...

    Authors: Roberto Cirocchi, Maria Ida Amabile, Alessandro De Luca, Federico Frusone, Domenico Tripodi, Patrizia Gentile, Renata Tabola, Daniele Pironi, Flavio Forte, Massimo Monti, Vito D’Andrea and Salvatore Sorrenti

    Citation: World Journal of Surgical Oncology 2021 19:93

    Content type: Review

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  18. Solitary fibrous tumours (SFTs) in the female genital tract are uncommon. Resection of these tumours is controversial because it can cause life-threatening haemorrhage. We report a case of vulvar SFT that was ...

    Authors: Akimasa Takahashi, Hiroki Nishimura, Tsukuru Amano, Mari Deguchi, Fumi Yoshino, Ryo Kasei, Fuminori Kimura, Suzuko Moritani and Takashi Murakami

    Citation: World Journal of Surgical Oncology 2021 19:92

    Content type: Case report

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  19. Lymph node metastasis is a major prognostic sign of colorectal carcinoma and an important indicator for individualized treatment. M2 macrophages play a key role in carcinogenesis and tumor development by enhan...

    Authors: Yanping Wang, Jikun Wang, Chunyu Yang, Yue Wang, Jinhao Liu, Zuoxiu Shi, Yanlei Chen, Yang Feng, Xueqian Ma and Shifeng Qiao

    Citation: World Journal of Surgical Oncology 2021 19:91

    Content type: Research

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  20. Recent researches have suggested that long noncoding RNA (lncRNA) is involved in the tumorigenesis and development of stomach cancer (SC). This meta-analysis aimed to identify the diagnostic performance of cir...

    Authors: Fang Cao, Yongwei Hu, Zaichang Chen, Wei Han, Weijie Lu, Jianhao Xu, Houzhong Ding and Xiaojun Shen

    Citation: World Journal of Surgical Oncology 2021 19:89

    Content type: Research

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  21. Accumulated evidence has demonstrated that aerobic glycolysis serves as a regulator of tumor cell growth, invasion, and angiogenesis. Herein, we explored the role of protein disulfide isomerase family 6 (PDIA6...

    Authors: Ling Mao, Xiaoweng Wu, Zhengpeng Gong, Ming Yu and Zhi Huang

    Citation: World Journal of Surgical Oncology 2021 19:88

    Content type: Research

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  22. The aim of this study was to compare the safety feasibility and safety feasibility of non-intubated (NIVATS) and intubated video-assisted thoracoscopic surgeries (IVATS) during major pulmonary resections.

    Authors: Wenfei Xue, Guochen Duan, Xiaopeng Zhang, Hua Zhang, Qingtao Zhao, Zhifei Xin and Jie He

    Citation: World Journal of Surgical Oncology 2021 19:87

    Content type: Research

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  23. Triple-negative breast cancer (TNBC) is a major subtype of breast cancer. Due to the lack of effective therapeutic targets, the prognosis is poor. In order to find an effective target, despite many efforts, th...

    Authors: Qianqian Yuan, Lewei Zheng, Yiqin Liao and Gaosong Wu

    Citation: World Journal of Surgical Oncology 2021 19:86

    Content type: Research

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  24. Effect of neoadjuvant chemotherapy (NAC) for pancreatic ductal adenocarcinoma (PDAC) has remained under investigation. We investigated its effect from a unique perspective and discussed its application.

    Authors: Yoshihiro Kurata, Takayuki Shiraki, Masanori Ichinose, Keiichi Kubota and Yasuo Imai

    Citation: World Journal of Surgical Oncology 2021 19:85

    Content type: Research

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  25. Colorectal cancer (CRC), the third most commonly diagnosed malignant carcinoma and the third most common cause of carcinoma-related mortality, continues to be a major international health problem. And approxim...

    Authors: An Shang, Shuang Wang, Yongping Yang, Liping Li, Zeyun Zhao, Donglin Li, Yu Guo and Min Wang

    Citation: World Journal of Surgical Oncology 2021 19:84

    Content type: Research

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  26. Gastric cancer is the fifth most common cancer worldwide, with an incidence of 6.72 per 100,000 people. Thirty-two percent of gastric cancer patients will live 5 years after diagnosis. Single-site metastasis i...

    Authors: Elizabeth Jacob, Levi Smucker, Ryan Crouse and Ayana Allard-Picou

    Citation: World Journal of Surgical Oncology 2021 19:83

    Content type: Case report

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  27. To reduce local recurrence risk, rectal washout (RW) is integrated in the total mesorectal excision (TME) technique when performing anterior resection (AR) for rectal cancer. Although RW is considered a safe p...

    Authors: Karl Teurneau-Hermansson, Rebecca Svensson Neufert, Pamela Buchwald and Fredrik Jörgren

    Citation: World Journal of Surgical Oncology 2021 19:82

    Content type: Research

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  28. There is still some debate as to whether transcatheter arterial chemoembolization (TACE) plus radiofrequency ablation (RFA) is better than TACE or RFA alone. This meta-analysis aimed to compare the efficacy an...

    Authors: Chuang Jiang, Gong Cheng, Mingheng Liao and Jiwei Huang

    Citation: World Journal of Surgical Oncology 2021 19:81

    Content type: Review

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  29. Many oncologists debate if lobular neoplasia (LN) is a risk factor or an obligatory precursor of more aggressive disease. This study has three aims: (i) describe the different treatment options (surgical resec...

    Authors: Jasna Metovic, Simona Osella Abate, Fulvio Borella, Elena Vissio, Luca Bertero, Giovanna Mariscotti, Manuela Durando, Rebecca Senetta, Ada Ala, Chiara Benedetto, Anna Sapino, Paola Cassoni and Isabella Castellano

    Citation: World Journal of Surgical Oncology 2021 19:80

    Content type: Research

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  30. Sarcomatoid carcinoma of the pancreas (SCP) is an extremely rare and aggressive disease with poor prognosis. We have already reported a rare case of SCP with long-term survival. In the present article, we inve...

    Authors: Toshihisa Kimura, Tamotsu Togawa, Atsushi Iida, Sakon Noriki, Yasunori Sato and Takanori Goi

    Citation: World Journal of Surgical Oncology 2021 19:79

    Content type: Correspondence

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  31. Hepatocellular carcinoma (HCC) can grow in a mosaic pattern, often combined with various non-hepatocellular cells. However, HCC combined with a neuroendocrine carcinoma (NEC) component is rarely reported, and ...

    Authors: Akira Nakano, Kenichi Hirabayashi, Hiroshi Yamamuro, Taro Mashiko, Yoshihito Masuoka, Seiichiro Yamamoto, Soji Ozawa and Toshio Nakagohri

    Citation: World Journal of Surgical Oncology 2021 19:78

    Content type: Case report

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  32. The aim of this study was to investigate the safety and clinical usefulness of early oral feeding (EOF) after rectosigmoid resection with anastomosis for the treatment of primary ovarian cancer.

    Authors: Kazuyoshi Kato, Kohei Omatsu, Sanshiro Okamoto, Maki Matoda, Hidetaka Nomura, Terumi Tanigawa, Yoichi Aoki, Mayu Yunokawa and Hiroyuki Kanao

    Citation: World Journal of Surgical Oncology 2021 19:77

    Content type: Research

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  33. Lymphovascular invasion (LVI) is an important risk factor for prognosis of breast cancer and an unfavorable prognostic factor in node-negative invasive breast cancer patients. The purpose of this study was to ...

    Authors: Bo Bae Choi

    Citation: World Journal of Surgical Oncology 2021 19:76

    Content type: Research

    Published on:

  34. Circular RNA (circRNA) plays an important role in regulating cell biological function and has been shown to be involved in cancer progression, including oral squamous cell carcinoma (OSCC). Circ-KIAA0907 has b...

    Authors: Wenjie Dong, Lei Zhao, Shiyang Zhang, Shijie Zhang and Hongyun Si

    Citation: World Journal of Surgical Oncology 2021 19:75

    Content type: Research

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  35. Inflammatory markers are measured following colorectal surgery to detect postoperative complications. However, the association of these markers preoperatively with subsequent postoperative course has not yet b...

    Authors: Sufana H. Alsaif, Ailín C. Rogers, Priscilla Pua, Paul T. Casey, Geoff G. Aherne, Ann E. Brannigan, Jurgen J. Mulsow, Conor J. Shields and Ronan A. Cahill

    Citation: World Journal of Surgical Oncology 2021 19:74

    Content type: Research

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  36. The incidence of adenocarcinoma of the esophagogastric junction (AEG) is rising every year; however, the mode of operation for Siewert II AEG is still controversial. Accumulating evidence has shown that transa...

    Authors: Yun Huang, Gang Liu, Xiumei Wang, Yan Zhang, Guijun Zou, Zhanwei Zhao, Zhen Cao, Huibin Zhao, Xinpu Yuan and Chaojun Zhang

    Citation: World Journal of Surgical Oncology 2021 19:73

    Content type: Research

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  37. Immediate breast reconstruction with skin-sparing (SSM) or nipple-sparing mastectomy (NSM) has become a common procedure. In this study, we evaluated the distance between breast tumor and skin in a series of p...

    Authors: Takaaki Fujii, Yuko Nakazawa, Misato Ogino, Sayaka Obayashi, Reina Yajima, Chikako Honda, Hideharu Nakamura, Takaya Makiguchi and Ken Shirabe

    Citation: World Journal of Surgical Oncology 2021 19:72

    Content type: Research

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  38. Epidemiological data on primary brain tumours (PBTs) are lacking due to the difficulty in case ascertainment among the population. Thus, we aimed to estimate mortality due to PBTs in China nationwide and the d...

    Authors: Bin Jiang, Hongmei Liu, Dongling Sun, Haixin Sun, Xiaojuan Ru, Jie Fu, Siqi Ge and Wenzhi Wang

    Citation: World Journal of Surgical Oncology 2021 19:71

    Content type: Research

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  39. Several aspects of the correlation between colon cancer and hemostatic markers are still unknown to many researchers in the field. In this study, we evaluated the association, if any, of preoperative platelet ...

    Authors: Berrin Papila Kundaktepe and Cigdem Papila

    Citation: World Journal of Surgical Oncology 2021 19:69

    Content type: Research

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  40. We present our 9-year consecutive case series of skull base chordomas and chondrosarcomas from a UK tertiary referral centre, discussing treatments offered and outcomes. This was carried out to improve underst...

    Authors: Christopher Metcalfe, Jameel Muzaffar, Kevin Kulendra, Paul Sanghera, Simon Shaw, Amjad Shad, Natarajan Saravanappa, Alessandro Paluzzi and Shahzada Ahmed

    Citation: World Journal of Surgical Oncology 2021 19:68

    Content type: Research

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  41. Hepatocellular carcinoma (HCC) is a common cancer and the leading cause is persistent hepatitis B virus (HBV) infection. We aimed to identify some core genes and pathways for HBV-related HCC.

    Authors: Mingxue Yu, Wenli Xu, Yusheng Jie, Jiahui Pang, Siqi Huang, Jing Cao, Jiao Gong, Xinhua Li and Yutian Chong

    Citation: World Journal of Surgical Oncology 2021 19:66

    Content type: Research

    Published on:

  42. Synovial sarcoma (SS) is a rare soft tissue tumor. Among different anatomical locations where it can be found, gastric localization is a very uncommon one. Based on soft tissue sarcoma guidelines, complete tum...

    Authors: Matteo Rivelli, Eduardo Fernandes, Cristian Conti, Laura Bernardoni, Sara Pecori, Sara Cingarlini and Corrado Pedrazzani

    Citation: World Journal of Surgical Oncology 2021 19:65

    Content type: Case report

    Published on:

  43. This paper aims to compare the efficacy and safety of recombinant human endostatin combined with chemotherapy in patients with squamous cell lung cancer (SqCLC).

    Authors: Li Feng, Zhicong Wang, Li Jing, Zhiguo Zhou, Shuai Shi, Ruoying Deng, Yibing Liu and Qingju Meng

    Citation: World Journal of Surgical Oncology 2021 19:64

    Content type: Research

    Published on:

  44. Laparoscopic resection of giant hepatoblastoma (HB) in children has long been a subject of controversy. Here, a new procedure of two-stage laparoscopic resection of giant HB in infants was firstly reported and...

    Authors: Yaohao Wu, Lexiang Zeng, Ronglin Qiu, Jie Zhang, Jianhang Su, Minyi Liao and Xiaogeng Deng

    Citation: World Journal of Surgical Oncology 2021 19:63

    Content type: Research

    Published on:

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