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  1. lncRNA-CDKN2B antisense RNA 1 (ANRIL) and SRY-box transcription factor 9 (SOX9) has abnormal expression in many tumors including glioma, but the underlying molecular mechanism is unclear. This study set out to...

    Authors: Youlu Sun, Yuesong Jing and Yuxin Zhang

    Citation: World Journal of Surgical Oncology 2021 19:287

    Content type: Research

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  2. To investigate the effect of Helicobacter pylori (H. pylori) eradication on the prognosis of postoperative early gastric cancer (EGC).

    Authors: Liang Wang, Jinfeng Wang, Sha Li, Fei Bai, Hailong Xie, Hanguo Shan, Zhuo Liu, Tiexiang Ma, Xiayu Tang, Haibing Tang, Ang Qin, Sanlin Lei and Chaohui Zuo

    Citation: World Journal of Surgical Oncology 2021 19:285

    Content type: Research

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  3. To determine the potential of the combination of DCE-MRI imaging method with DWI and serum CA125 and CA199 levels in the evaluation of the efficacy of neoadjuvant chemotherapy in breast cancer patients.

    Authors: Jun Zhang, Yongbo Huang, Jianghui Chen, Xia Wang and Hongyu Ma

    Citation: World Journal of Surgical Oncology 2021 19:284

    Content type: Research

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  4. To study the clinical value of miR-135 and miR-20a combined with multi-detector computed tomography (MDCT) in the diagnosis of gastric cancer (GC).

    Authors: Wenwen Han, Xiangzhen Bu, Yanli Liu, Fang Liu, Yujie Ren, Yongsheng Cui and Shuhong Kong

    Citation: World Journal of Surgical Oncology 2021 19:283

    Content type: Research

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  5. To explore the clinical outcomes and effect on intraoperative blood loss and postoperative pain of patients undergoing the retroperitoneal laparoscopic partial nephrectomy (RLPN) for complex renal tumors.

    Authors: Yansong Guo, Qian Xu, Baochun Chen, Lifeng Liu, Yuanyuan Wang, Ai Zhu and Longjiang Tian

    Citation: World Journal of Surgical Oncology 2021 19:282

    Content type: Research

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  6. The administration of postoperative radiotherapy remains controversial in pN1 oral cavity cancer patients without extranodal extension. The aim is to determine whether postoperative radiotherapy reduces the ne...

    Authors: Tsung-You Tsai, Yenlin Huang, Andrea Iandelli, Shiao-Fwu Tai, Shao-Yu Hung, Huang-Kai Kao and Kai-Ping Chang

    Citation: World Journal of Surgical Oncology 2021 19:279

    Content type: Research

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  7. We conducted a study to explore the relationship between pathological cytomorphologic features and the percentage of anaplastic lymphoma kinase (ALK)-positive cells to better predict pulmonary adenocarcinoma p...

    Authors: Fenge Jiang, Congcong Wang, Ping Yang, Ping Sun and Jiannan Liu

    Citation: World Journal of Surgical Oncology 2021 19:278

    Content type: Research

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  8. Skin autofluorescence (SAF) reflects accumulation of advanced glycation end-products (AGEs). The aim of this study was to evaluate predictive usefulness of SAF measurement in prediction of acute kidney injury ...

    Authors: Maciej Krasnodębski, Karolina Grąt, Marcin Morawski, Jan Borkowski, Piotr Krawczyk, Andriy Zhylko, Michał Skalski, Piotr Kalinowski, Krzysztof Zieniewicz and Michał Grąt

    Citation: World Journal of Surgical Oncology 2021 19:276

    Content type: Research

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  9. Squamous cell carcinoma (SCC) is a disease with distinct management complexities as it displays a remarkably heterogeneous molecular subtype. However, the landscape of angiogenesis for SCC is not fully investi...

    Authors: Fanglu Qin, Shenghua Lin, Kun Deng, Junqi Qin, Zhanyu Xu, Liqiang Yuan, Jiangbo Wei, Yu Sun, Tiaozhan Zheng and Shikang Li

    Citation: World Journal of Surgical Oncology 2021 19:275

    Content type: Research

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  10. Dihydropyrimidinase like 2 (DPYSL2) has been linked to tumor metastasis. However, the function of DPSY2L in lung adenocarcinoma (LUAD) is yet to be explored.

    Authors: Yang-Jie Wu, Ai-Tao Nai, Gui-Cheng He, Fei Xiao, Zhi-Min Li, San-Yuan Tang, Yan-Ping Liu and Xiao-Hong Ai

    Citation: World Journal of Surgical Oncology 2021 19:274

    Content type: Research

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  11. Breast cancer is the most common malignancy in women. Cancer driver gene-mediated alterations in the tumor microenvironment are critical factors affecting the biological behavior of breast cancer. The purpose ...

    Authors: Xiao-wei Du, Gao Li, Juan Liu, Chun-yan Zhang, Qiong Liu, Hao Wang and Ting-song Chen

    Citation: World Journal of Surgical Oncology 2021 19:273

    Content type: Research

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  12. To evaluate whether the addition of taxanes to platinum and fluoropyrimidines in adjuvant chemotherapy would result in longer survival than platinum plus fluoropyrimidines in gastric cancer patients who receiv...

    Authors: Lili Wu, Ying Feng, Zhijun Wu, Hui Xu, Cheng Zhang, Jie Ning, Rong Wang, Jianqiong Chen, Minmin Xie, Yi Zhang, Lijia Bu, Jiqing Hao and Tai Ma

    Citation: World Journal of Surgical Oncology 2021 19:272

    Content type: Research

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  13. The safety and efficacy of indocyanine green (ICG) imaging navigational laparoscopic gastrectomy remain controversial. This study is to evaluate the short-term and long-term outcomes of ICG-guided laparoscopic...

    Authors: Xiaofeng Lu, Song Liu, Xuefeng Xia, Feng Sun, Zhijian Liu, Jiafeng Wang, Xianghui Li, Zhengyang Yang, Xing Kang, Shichao Ai and Wenxian Guan

    Citation: World Journal of Surgical Oncology 2021 19:271

    Content type: Research

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  14. The abnormal expression of microRNA (miRNA) has been proved to be closely related to the occurrence and progression of tumors. A unique expression of multiple miRNAs has been found in different types of tumors...

    Authors: Qizhi Zhang, Ying Wang, Yinting Zhou, Qiujuan Zhang and Chuan Xu

    Citation: World Journal of Surgical Oncology 2021 19:270

    Content type: Research

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  15. Pedunculated polyps are more likely to be amenable to complete resection than non-pedunculated early colorectal cancers and rarely require additional surgery. We encountered a patient with a pedunculated early...

    Authors: Hiroka Kondo, Shimpei Ogawa, Takeshi Ohki, Yoshiko Bamba, Yuka Kaneko, Kurodo Koshino, Ryosuke Nakagawa, Kimitaka Tani, Fumi Maeda, Hisako Aihara, Fumiaki Tokito, Shuji Fujikawa, Tomoko Yamamoto, Yoji Nagashima, Yuji Inoue, Michio Itabashi…

    Citation: World Journal of Surgical Oncology 2021 19:269

    Content type: Case report

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  16. Circular RNA 0029803 (circ_0029803) was found to be upregulated in colorectal cancer (CRC) tissues, but its function and underlying molecular mechanism are not studied in CRC.

    Authors: Linfei Huang, Lei Zhu, Sheng Pan, Jing Xu, Miao Xie, Wei Wang and Ganlin Xia

    Citation: World Journal of Surgical Oncology 2021 19:268

    Content type: Research

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  17. Extraskeletal osteosarcoma (ESOS) is a rare mesenchymal malignancy, which produces osteoid, bone, or chondroid material and is located in the soft tissue without attachment to skeletal bones and periosteum. On...

    Authors: Xinyang Nie, Weihua Fu, Chuan Li, Li Lu and Weidong Li

    Citation: World Journal of Surgical Oncology 2021 19:267

    Content type: Case report

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  18. MicroRNA-140 (miR-140) is one of the most widely investigated miRNAs in cell carcinogenesis and cancer development. Despite present proposals of employing miR-140 as a candidate biomarker for cancer prognosis,...

    Authors: Mengxia Zheng, Jingting Liu, Chunyan Meng, Kaifeng Tang and Jianhua Liao

    Citation: World Journal of Surgical Oncology 2021 19:266

    Content type: Review

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  19. Colorectal cancer (CRC) is one of the most frequent neoplasms in the world. Based on the emerging role of noncoding RNAs, particularly circular RNAs in pathogenesis of cancers, we designed this study to inspec...

    Authors: Sepideh Kadkhoda, Reza Taslimi, Farshid Noorbakhsh, Farzaneh Darbeheshti, Javad Tavakkoly Bazzaz, Soudeh Ghafouri-Fard and Abbas Shakoori

    Citation: World Journal of Surgical Oncology 2021 19:265

    Content type: Research

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  20. Studies on PD-L1 expression in breast cancer have gained importance in recent years, especially in triple-negative breast cancer (TNBC). Our aim was to analyze the differential expression of PD-L1 to explore i...

    Authors: Gizem Oner, Semen Önder, Hüseyin Karatay, Naziye Ak, Mustafa Tükenmez, Mahmut Müslümanoğlu, Abdullah İğci, Ahmet Dincçağ, Vahit Özmen, Adnan Aydiner, Ekrem Yavuz and Neslihan Cabioğlu

    Citation: World Journal of Surgical Oncology 2021 19:264

    Content type: Research

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  21. The optimal axillary lymph node (ALN) management strategy in patients diagnosed with ductal carcinoma in situ (DCIS) preoperatively remains controversial. The value of breast magnetic resonance imaging (MRI) t...

    Authors: Hung-Wen Lai, Yi-Lin Chang, Shou-Tung Chen, Yu-Jun Chang, Wen-Pei Wu, Dar-Ren Chen, Shou-Jen Kuo, Chiung-Ying Liao and Hwa-Koon Wu

    Citation: World Journal of Surgical Oncology 2021 19:263

    Content type: Research

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  22. This study aimed to investigate the correlation between miRNA-216b expression in patients with non-small cell lung cancer (NSCLC) and 18F-fluorodeoxyglucose (FDG) uptake by PET/CT and to explore the clinical appl...

    Authors: Mingfei Zuo, Lan Yao, Lijuan Wen, Jianfei Shen, Na Zhang, Tian Bai and Qicheng Huang

    Citation: World Journal of Surgical Oncology 2021 19:262

    Content type: Research

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  23. Frozen section (FS) pathology has multiple limitations, and different institutions report variable experiences with the use of FS for diagnosis of tumor involvement. We aimed to compare the FS accuracy with th...

    Authors: Zahra Mehdipour Namdar, Navid Omidifar, Peyman Arasteh, Majid Akrami, Sedigheh Tahmasebi, Aida Salehi Nobandegani, Sogol Sedighi, Vahid Zangouri and Abdolrasoul Talei

    Citation: World Journal of Surgical Oncology 2021 19:261

    Content type: Research

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  24. The study aimed to compare the Steroid 5 alpha-reductase 3 (SRD5A3) expression levels in breast cancer (BC) and normal tissues, to investigate the prognostic value of SRD5A3 mRNA expression in BC patients and ...

    Authors: Yong-ping Zhang, Wen-ting Na, Xiao-qiang Dai, Ruo-fei Li, Jian-xiong Wang, Ting Gao, Wei-bo Zhang and Cheng Xiang

    Citation: World Journal of Surgical Oncology 2021 19:260

    Content type: Research

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  25. The aberrant expression of circular RNAs (circRNAs) plays vital roles in the advancement of human cancers, including gastric cancer (GC). In this study, the functions of circRNA ring finger protein 111 (circ-R...

    Authors: Guoxian Wu, Aimin Zhang, Yinglin Yang and Dongping Wu

    Citation: World Journal of Surgical Oncology 2021 19:259

    Content type: Research

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  26. The standard treatment of stage III N2 small cell lung cancer (SCLC) is concurrent chemoradiation, and surgery is not recommended. This study was aimed to evaluate whether surgery has survival benefits in pati...

    Authors: Yanfei Chai, Yuchao Ma, Wei Feng, Hongwei Lu and Longyu Jin

    Citation: World Journal of Surgical Oncology 2021 19:258

    Content type: Research

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  27. To establish a risk prediction model for pancreatic fistula according to the pancreatic fistula standards of the 2016 edition.

    Authors: Jun Yu, Chao-yi Ren, Jun Wang, Wei Cui, Jin-juan Zhang and Yi-jun Wang

    Citation: World Journal of Surgical Oncology 2021 19:257

    Content type: Research

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  28. To evaluate the clinicopathologic value of morphological growth patterns of small renal cell carcinoma (sRCC) and determine the actual demand for taking a rim of healthy parenchyma to avoid positive SM.

    Authors: Gang Li, Tengfei Xiao, Keruo Wang, Renya Zhang, Aixiang Wang, Chengzhi Yan and Chunhui Wang

    Citation: World Journal of Surgical Oncology 2021 19:255

    Content type: Research

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  29. Li-Fraumeni is a rare autosomal dominant cancer predisposition syndrome. The basis is a germline mutation of TP53 gene which encodes tumor suppressor protein resulting in early onset of tumors, most often breast ...

    Authors: Juraj Prejac, Natalija Dedić Plavetić, Kristina Gotovac Jerčić and Fran Borovečki

    Citation: World Journal of Surgical Oncology 2021 19:254

    Content type: Case report

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  30. The impact of primary tumour location on the prognosis of patients with peritoneal metastasis (PM) arising from colorectal cancer (CRC) after cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemot...

    Authors: Haipeng Chen, Sicheng Zhou, Jianjun Bi, Qiang Feng, Zheng Jiang, Jianping Xu, Wei Pei, Jianwei Liang, Zhixiang Zhou and Xishan Wang

    Citation: World Journal of Surgical Oncology 2021 19:253

    Content type: Research

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  31. The aim of this study was to identify predictors of mortality in elderly patients undergoing colorectal cancer surgery and to develop a risk score.

    Authors: Nerea González, Ane Loroño, Urko Aguirre, Santiago Lázaro, Marisa Baré, Maximino Redondo, Eduardo Briones, Cristina Sarasqueta, Amaia Bilbao, Nerea Fernández de Larrea and José María Quintana

    Citation: World Journal of Surgical Oncology 2021 19:252

    Content type: Research

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  32. There have been controversial voices on if hepatitis B virus infection decreases the risk of colorectal liver metastases or not. This study aims to the find the association between HBV infection and postoperat...

    Authors: Ziyao Li, Shaofei Li, Hangbo Tao, Yixiang Zhan, Kemin Ni, Jianfeng Gong and Guoxun Li

    Citation: World Journal of Surgical Oncology 2021 19:251

    Content type: Research

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  33. To retrospectively analyze the safety and long-term clinical efficacy of gelatin sponge microparticles combined with the chemotherapy drug pirarubicin for hepatic transcatheter arterial chemoembolization (GSMs...

    Authors: Guang Sheng Zhao, Song Liu, Ying Liu, Jian Ma, Ruo Yu Wang, Jie Bian, Jun Zhou, Jian Lin Wu and Yue Wei Zhang

    Citation: World Journal of Surgical Oncology 2021 19:249

    Content type: Research

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  34. Colorectal cancer (CRC) is one of the most common cancers of the gastrointestinal tract and ranks third in cancer-related deaths worldwide. This study was conducted to identify novel biomarkers related to the ...

    Authors: Xuan Yang, Wangao Wei, Shisheng Tan, Linrui Guo, Song Qiao, Biao Yao and Zi Wang

    Citation: World Journal of Surgical Oncology 2021 19:248

    Content type: Research

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  35. Previous studies had shown that microRNA-638 (miR-638) exhibited different effects in malignant tumors. Moreover, the function of miR-638 has not been reported in breast cancer. Hence, we designed this researc...

    Authors: Qian Xu, Qianqian Zhang, Mengli Dong and Yuan Yu

    Citation: World Journal of Surgical Oncology 2021 19:247

    Content type: Research

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  36. Circular RNAs (circRNAs) are increasingly implicated in regulating human carcinogenesis. Previous work showed the oncogenic activity of circ_0018289 in cervical cancer. However, the molecular basis underlying ...

    Authors: Heng Zou, Huijia Chen, Shuaibin Liu and Xiaoling Gan

    Citation: World Journal of Surgical Oncology 2021 19:246

    Content type: Research

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  37. The optimal treatment in patients with gastric cancer and peritoneal disease remains controversial. Some guidelines indicate palliative treatment only, while others consider surgical treatment in case of posit...

    Authors: Massimiliano Valletti, Dilmurodjon Eshmuminov, Nicola Gnecco, Christian Alexander Gutschow, Paul Magnus Schneider and Kuno Lehmann

    Citation: World Journal of Surgical Oncology 2021 19:245

    Content type: Research

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  38. Adequate margins are technically difficult to achieve for malignant tumors involving the sacroiliac joint due to limited accessibility and viewing window. In order to address the technical difficulties faced i...

    Authors: Tao Ji, Brian Z. J. Chin, Xiaodong Tang, Rongli Yang and Wei Guo

    Citation: World Journal of Surgical Oncology 2021 19:243

    Content type: Research

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  39. To investigate the expression and clinical significance of EFNA1 in broad-spectrum tumors, and to evaluate its relationship with prognosis and biological functions of esophageal carcinoma (ESCA).

    Authors: Yongqiang Zhang, Jinning Zhang, Guanlong Pan, Tianhao Guan, Changhao Zhang, An Hao, Yan Li and Hai Ren

    Citation: World Journal of Surgical Oncology 2021 19:242

    Content type: Research

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  40. Hepatocellular carcinoma (HCC) is one of the most common malignancies in the world, and due to its complex pathogenic factors, its prognosis is poor. N6-methyladenosine (m6A) RNA methylation plays an important ro...

    Authors: Jihao Cai, Minglei Zhou and Jianxin Xu

    Citation: World Journal of Surgical Oncology 2021 19:241

    Content type: Research

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  41. Oral cancer (OC) is a common and dangerous malignant tumor with a low survival rate. However, the micro level mechanism has not been explained in detail.

    Authors: Abdusemer Reyimu, Ying Chen, Xudong Song, Wubi Zhou, Jingjing Dai and Feng Jiang

    Citation: World Journal of Surgical Oncology 2021 19:240

    Content type: Research

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  42. miR-92b is a carcinogenic miRNA that has great potential as a biomarker for disease prognosis, diagnosis, and treatment in the clinic. It is of great significance to analyse the relationship between miR-92b an...

    Authors: Yu Du, Zhuang Miao, Kedi Wang, Yan Lv, Lijuan Qiu and Lusheng Guo

    Citation: World Journal of Surgical Oncology 2021 19:239

    Content type: Research

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  43. This article is a commentary on an article published in World Journal of Surgical Oncology by Liu et al. With this study, authors evaluated diagnostic accuracy of Xpert bladder cancer monitor in detecting recurre...

    Authors: Gopal Sharma

    Citation: World Journal of Surgical Oncology 2021 19:237

    Content type: Correspondence

    Published on:

    The original article was published in World Journal of Surgical Oncology 2021 19:42

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