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  1. PDZ-binding kinase (PBK) encodes a serine/threonine protein kinase related to the dual specific mitogen-activated protein kinase kinase (MAPKK) family. There is evidence that overexpression of this gene is ass...

    Authors: Wei Mu, Yaoli Xie, Jinhu Li, Runzhi Yan, Jingxian Zhang, Yu’e Liu and Yimin Fan

    Citation: World Journal of Surgical Oncology 2022 20:22

    Content type: Research

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  2. Colorectal cancer is the most common malignancy and the third leading cause of cancer-related death worldwide. This study aimed to identify potential diagnostic biomarkers for colorectal cancer by genome-wide ...

    Authors: Xin Zhang, Tao Li, Qiang Niu, Chang-jiang Qin, Ming Zhang, Guang-ming Wu, Hua-zhong Li, Yan Li, Chen Wang, Wen-fei Du, Chen-yang Wang, Qiang Zhao, Xiao-dong Zhao, Xiao-liang Wang and Jian-bin Zhu

    Citation: World Journal of Surgical Oncology 2022 20:21

    Content type: Research

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  3. To achieve excellent postoperative bowel function in familial adenomatous polyposis (FAP) patients, it is important to reconstruct the digestive tract. The aim of this study is to preliminarily discuss the adv...

    Authors: Tianci Qin, Jiankun Liao, Haiquan Qin, Linghou Meng, Wentao Wang, Zigao Huang, Jungang Liu and Xianwei Mo

    Citation: World Journal of Surgical Oncology 2022 20:20

    Content type: Research

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  4. Early postoperative small bowel obstruction (EPSBO) is a common complication after colorectal cancer surgery. Few studies have specifically studied risk factors for early small bowel obstruction after right co...

    Authors: Huida Zheng, Yurong Liu, Zhenze Chen, Yafeng Sun and Jianhua Xu

    Citation: World Journal of Surgical Oncology 2022 20:19

    Content type: Research

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  5. Lipid disequilibrium and systemic inflammation are reported to correlate with tumorigenesis and development of colorectal cancer (CRC). We construct the novel biomarker cholesterol-to-lymphocyte ratio (CLR) to...

    Authors: Siyu Zhou, Qian He, Nengquan Sheng, Jianfeng Gong, Jiazi Ren and Zhigang Wang

    Citation: World Journal of Surgical Oncology 2022 20:18

    Content type: Research

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  6. This study aimed to analyze the clinical and pathological features of extrauterine endometrial stromal sarcoma (EESS) and explore an effective therapeutic regimen to reduce the recurrence rate in low-grade EES...

    Authors: You Wu, Nan Li, Rong Zhang and Ping Bai

    Citation: World Journal of Surgical Oncology 2022 20:17

    Content type: Research

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  7. Cancer is one of the critical issues of the global health system with a high mortality rate even with the available therapies, so using novel therapeutic approaches to reduce the mortality rate and increase th...

    Authors: Ali Zarezadeh Mehrabadi, Fatemeh Roozbahani, Reza Ranjbar, Mahdieh Farzanehpour, Alireza Shahriary, Ruhollah Dorostkar and Hadi Esmaeili Gouvarchin Ghaleh

    Citation: World Journal of Surgical Oncology 2022 20:16

    Content type: Review

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  8. The crucial oncogenic role of cancer stem cells (CSCs) in tumor maintenance, progression, drug resistance, and relapse has been clarified in different cancers, particularly in colorectal cancer (CRC). The curr...

    Authors: Elham Kalantari, Tahereh Taheri, Saba Fata, Maryam Abolhasani, Mitra Mehrazma, Zahra Madjd and Mojgan Asgari

    Citation: World Journal of Surgical Oncology 2022 20:15

    Content type: Research

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  9. The degree of contamination of healthy tissue with tumor cells during a biopsy in bone or soft tissue sarcomas is clearly dependant on the type of biopsy. Some studies have confirmed a clinically relevant cont...

    Authors: Alexander Klein, Christof Birkenmaier, Julian Fromm, Thomas Knösel, Dorit Di Gioia and Hans Roland Dürr

    Citation: World Journal of Surgical Oncology 2022 20:14

    Content type: Research

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  10. Circular RNAs (circRNAs) are a novel type of endogenous RNAs and play vital roles in lung adenocarcinoma. However, the function and underlying mechanism of circ_0020850 in lung adenocarcinoma remain unknown.

    Authors: Xiaoju Li, Shengtian Su, Dan Ye, Zhigao Yu, Wenjing Lu and Liang Liu

    Citation: World Journal of Surgical Oncology 2022 20:13

    Content type: Research

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  11. Numerous studies have addressed lymphovascular invasion (LVI) in patients with thoracic oesophageal squamous cell carcinoma (ESCC); however, little is known about the individual roles of lymphatic invasion (LI...

    Authors: Yu Ma, Xi Yao, Zhenzhen Li, Jie Chen, Wensheng Li, Hongtao Wang, Lanjun Zhang and Jianfei Zhu

    Citation: World Journal of Surgical Oncology 2022 20:12

    Content type: Research

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  12. The overall survival of patients  with pancreatic cancer is extremely low. Despite multiple large-scale studies, identification of predictors of patient survival remains challenging. This study aimed to invest...

    Authors: Qi Li, Zijian Feng, Ruyi Miao, Xun Liu, Chenxi Liu and Zhen Liu

    Citation: World Journal of Surgical Oncology 2022 20:11

    Content type: Research

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  13. Patients with gastric cancer are aging in Japan. It is not clear which patients and which surgical procedures have survival benefits after gastrectomy. A multivariate analysis was performed.

    Authors: Shunji Endo, Tomoki Yamatsuji, Yoshinori Fujiwara, Masaharu Higashida, Hisako Kubota, Hideo Matsumoto, Hironori Tanaka, Toshimasa Okada, Kazuhiko Yoshimatsu, Ken Sugimoto and Tomio Ueno

    Citation: World Journal of Surgical Oncology 2022 20:10

    Content type: Research

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  15. Malignant peripheral nerve sheath tumor (MPNST) is a rare soft tissue sarcoma mainly treated via surgical resection. Herein, we report a case of MPNST wherein a massive tumor thrombus extended to the major vei...

    Authors: Toru Hirozane, Robert Nakayama, Sayaka Yamaguchi, Tomoaki Mori, Naofumi Asano, Keisuke Asakura, Kazutaka Kikuta, Miho Kawaida, Aya Sasaki, Hajime Okita, Seishi Nakatsuka and Tsutomu Ito

    Citation: World Journal of Surgical Oncology 2022 20:8

    Content type: Case report

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  16. The efficacy of preoperative biliary drainage (PBD) has been debated for several decades, and yet indications for PBD remain controversial. The aim of this study was to compare the postoperative morbidity and ...

    Authors: Zhihui Gao, Jie Wang, Sheng Shen, Xiaobo Bo, Tao Suo, Xiaoling Ni, Han Liu, Lihong Huang and Houbao Liu

    Citation: World Journal of Surgical Oncology 2022 20:7

    Content type: Research

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  17. Lymphedema is a progressive, noncurable condition consisting of increases in subcutaneous fat and interstitial fluid in the limbs and fibrosis during later stages. The disease most commonly affects the limbs f...

    Authors: Jianfeng Xin, Yuguang Sun, Song Xia, Kun Chang, Chao Dong, Zhong Liu, Jian Dong and Wenbin Shen

    Citation: World Journal of Surgical Oncology 2022 20:6

    Content type: Research

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  18. Pathological extramural venous invasion (EMVI) is defined as the active invasion of malignant cells into veins beyond the muscularis propria in colorectal cancer. It is associated with poor prognosis and incre...

    Authors: Tomoki Abe, Masayoshi Yasui, Hiroki Imamura, Chu Matsuda, Junichi Nishimura, Naotsugu Haraguchi, Nozomu Nakai, Hiroshi Wada, Hidenori Takahashi, Takeshi Omori, Hiroshi Miyata and Masayuki Ohue

    Citation: World Journal of Surgical Oncology 2022 20:5

    Content type: Research

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  19. Stromal cells in tumor microenvironment could promote immune escape through a variety of mechanisms, but there are lacking research in the field of gastric cancer (GC).

    Authors: Junyu Huo, Ge Guan, Jinzhen Cai and Liqun Wu

    Citation: World Journal of Surgical Oncology 2022 20:4

    Content type: Research

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  20. We report two rare cases of retroperitoneal schwannoma completely resected by a laparoscopic medial-retroperitoneal approach aided by virtual navigation. Three-dimensional images have been used in liver and lu...

    Authors: Yuta Sato, Nobuhisa Matsuhashi, Yuto Sugie, Masashi Kuno, Shigeru Kiyama, Yoshihiro Tanaka, Naoki Okumura, Takao Takahashi, Takuya Saiki and Kazuhiro Yoshida

    Citation: World Journal of Surgical Oncology 2022 20:3

    Content type: Case report

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  22. To explore the correlation between the preoperative systemic immune inflammation index (SII) and the prognosis of patients with gastric carcinoma (GC).

    Authors: Xu Zhaojun, Chen Xiaobin, An Juan, Yuan Jiaqi, Jiang Shuyun, Liu Tao, Cai Baojia, Wang Cheng and Ma Xiaoming

    Citation: World Journal of Surgical Oncology 2022 20:1

    Content type: Research

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  23. The outbreak of COVID-19 pandemic led to a 2-month lockdown in Europe. Elective surgeries, including skin cancer excisions, were postponed. The purpose of this prospective case-control study was to assess the ...

    Authors: Konstantinos Seretis, Eleni Boptsi, Anastasia Boptsi and Efstathios G. Lykoudis

    Citation: World Journal of Surgical Oncology 2021 19:350

    Content type: Research

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  24. Previous studies on sternocleidomastoid flaps, have defined the importance of preserving sternocleidomastoid (SCM) branch of superior thyroid artery (STA). This theory drew criticism, as this muscle is known t...

    Authors: Apurva Srivastava, Tarun Kumar, Shashi Kant Pandey, Ram Chandra Shukla, Esha Pai and Manoj Pandey

    Citation: World Journal of Surgical Oncology 2021 19:349

    Content type: Research

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  25. Immediate reconstruction (IR) is a safe and effective surgical treatment for patients with breast cancer. We aimed to assess the prognosis, aesthetic outcomes, and patient satisfaction of IR compared with brea...

    Authors: Yanni Song, Shanshan Sun, Dalin Li, Jiguang Han, Ming Niu, Sai Luo, Haiqian Xu, Rui Huang, Sihang Zhang, Yang Wu, Qiqi Wu, Jing Xiong and Lijun Hao

    Citation: World Journal of Surgical Oncology 2021 19:348

    Content type: Research

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  26. We investigated the usefulness of gasless laparoscopic surgery (GLS) using a subcutaneous abdominal wall lifting method for endometrial cancer.

    Authors: Hiroe Ito, Tetsuya Moritake, Fumitoshi Terauchi and Keiichi Isaka

    Citation: World Journal of Surgical Oncology 2021 19:347

    Content type: Research

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  27. Regulation of single nucleotide polymorphisms (SNP) in micro-RNA (miRNA) on the host cells may be one of the most important factors influencing the occurrence of cervical cancer based on the prevalence of HPV ...

    Authors: Jingyu Xu, Junze Geng, Qiang Zhang, Yihua Fan, Zijun Qi and Tian Xia

    Citation: World Journal of Surgical Oncology 2021 19:346

    Content type: Research

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  28. The study aimed to assess the value of circulating tumor cells (CTCs) as a prognostic and treatment response marker in patients undergoing androgen deprivation therapy (ADT) plus cryosurgery vs. ADT alone for ...

    Authors: Mingxiong Sheng, Shanming Guo and Chunxiao Liu

    Citation: World Journal of Surgical Oncology 2021 19:345

    Content type: Research

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  29. This study aimed to establish a radiomics-based nomogram for predicting severe (grade B or C) post-hepatectomy liver failure (PHLF) in patients with huge (≥ 10 cm) hepatocellular carcinoma (HCC).

    Authors: Fei Xiang, Xiaoyuan Liang, Lili Yang, Xingyu Liu and Sheng Yan

    Citation: World Journal of Surgical Oncology 2021 19:344

    Content type: Research

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  30. Cervical cancer shows great differences in depth of invasion, metastasis, and other biological behaviors. The location of the lesion is special, so it is usually difficult to determine the clinical stage. This...

    Authors: Chao Ran, Jian Sun, Yunhui Qu and Na Long

    Citation: World Journal of Surgical Oncology 2021 19:343

    Content type: Research

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  32. Early detection of colorectal cancer (CRC) improves prognosis, yet many CRCs are diagnosed following symptoms. The aim of this study was to determine which CRC-related symptoms or signs can predict an advanced...

    Authors: Rotem Gvirtzman, Dan Meir Livovsky, Esther Tahover, Eran Goldin and Benjamin Koslowsky

    Citation: World Journal of Surgical Oncology 2021 19:341

    Content type: Research

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  34. Low-grade myofibroblastic sarcoma (LGMS) is a poorly studied, rare, soft tissue sarcoma. LGMS is characterized by a low malignancy potential, tendency for local recurrence, and low likelihood of distant metast...

    Authors: Jong-Ho Kim, Woosuk Choi, Hwan Seong Cho, Kyu Sang Lee, Joseph Kyu-hyung Park and Baek-Kyu Kim

    Citation: World Journal of Surgical Oncology 2021 19:339

    Content type: Research

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  35. Prostate cancer is the most common malignant tumor in men. Due to the lack of theoretical research on its pathogenic mechanism, the current cure rate is still low. miRNAs play an important role in the pathogen...

    Authors: Guangchi Xu, Yin Meng, Lihe Wang, Bo Dong, Feifei Peng, Songtao Liu, Shukui Li and Tao Liu

    Citation: World Journal of Surgical Oncology 2021 19:338

    Content type: Research

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  36. The prognosis of obstructive colorectal cancer (oCRC) is worse than that of nonobstructive colorectal cancer. However, no previous study has established an individualized prediction model for the prognosis of ...

    Authors: Jian Lv, Yuan yuan Liu, Yi tao Jia, Jing li He, Guang yao Dai, Peng Guo, Zhao long Zhao, Yan ni Zhang and Zhong xin Li

    Citation: World Journal of Surgical Oncology 2021 19:337

    Content type: Research

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  38. Accumulating evidence demonstrated that circular RNAs (circRNAs) play pivotal regulatory roles in the pathology of cancers. Disclosing the roles and molecular mechanisms of circRNAs in tumorigenesis and develo...

    Authors: Xiaoyang Liu, Yang Cheng, Yan Wang and Yinhong Zhang

    Citation: World Journal of Surgical Oncology 2021 19:335

    Content type: Research

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  39. The present study provides a snapshot of Italian patients with peritoneal metastasis from gastric cancer treated by surgery in Italian centers belonging to the Italian Research Group on Gastric Cancer. Prognos...

    Authors: Luigina Graziosi, Elisabetta Marino, Maria Bencivenga, Alessia D’Ignazio, Leonardo Solaini, Silvia Ministrini, Michela Caprioli, Michele Sacco, Daniele Marrelli, Gianni Mura, Maurizio Degiuli, Paolo Morgagni, Guido Alberto Massimo Tiberio, Giovanni De Manzoni, Franco Roviello and Annibale Donini

    Citation: World Journal of Surgical Oncology 2021 19:334

    Content type: Research

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  40. Camrelizumab (a PD-1 inhibitor) has been used as a potential therapy in unresectable advanced esophageal squamous cell carcinoma (ESCC) along with adjuvant treatment in locally advanced ESCC, exhibiting an acc...

    Authors: Peng Yang, Xiao Zhou, Xuefeng Yang, Yuefeng Wang, Tao Sun, Shiying Feng and Xianyou Ma

    Citation: World Journal of Surgical Oncology 2021 19:333

    Content type: Research

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  41. Capecitabine is a prodrug that is enzymatically converted to its active form, fluorouracil (also called 5-fluorouracil), which is commonly used as adjuvant chemotherapy in colorectal cancer patients. Severe ga...

    Authors: You Zou, Shuang Liu, Jianhong Wu and Zhen Sun

    Citation: World Journal of Surgical Oncology 2021 19:332

    Content type: Case report

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  42. Inflammatory myofibroblastic tumour is an infrequent mesenchymal neoplasia of unknown aetiology and variable behaviour, ranging from rather benign lesions to locally aggressive and even metastatic disease. Its...

    Authors: Alfonso López de Sa, Alejandro Pascual, Javier Garcia Santos, Ramiro Mendez, Monica Bellon, Mar Ramirez, Fatima Matute, Cristina del Arco, Aránzazu Manzano, Pluvio Coronado, Antonio Casado and Gloria Marquina

    Citation: World Journal of Surgical Oncology 2021 19:331

    Content type: Case report

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  43. HER2 is a member of the ERBB family of receptor tyrosine kinases, and HER2 mutations occur in 1–4% of non-small cell lung cancer (NSCLC) as an oncogenic driver mutation. We found a rare mutation of HER2 p.Asp7...

    Authors: Huanhuan Xu, Qi Liang, Xian Xu, Shanyue Tan, Sumeng Wang, Yiqian Liu and Lingxiang Liu

    Citation: World Journal of Surgical Oncology 2021 19:330

    Content type: Case report

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  44. This study aims to screen and identify the biological functions and prognostic value of CXC chemokines in ovarian cancer (OC) through bioinformatics and molecular biology methods, and to provide data support f...

    Authors: Weiyuan Li, Ji-Ao Ma, Xun Sheng and Chunjie Xiao

    Citation: World Journal of Surgical Oncology 2021 19:329

    Content type: Research

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  45. Paraneoplastic neurological syndromes constitute rare neurological complications of malignant disease, manifesting in <1% of patients with cancer. Opsoclonus-myoclonus syndrome (OMS) presents with chaotic ocul...

    Authors: Aikaterini Kostoglou, Dimitrios Vlastos, Athanasios Bakalis and Debashis Ghosh

    Citation: World Journal of Surgical Oncology 2021 19:328

    Content type: Case report

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  46. In-transit metastasis is considered a locoregional disease in cutaneous melanoma (CM) patients. Isolated limb perfusion (ILP) is among the treatment options in selected cases. The aim of this study was to dete...

    Authors: Şevket Barış Morkavuk, Serdar Çulcu, Ebru Esen and Ali Ekrem Ünal

    Citation: World Journal of Surgical Oncology 2021 19:327

    Content type: Research

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  48. Surgical devices are commonly used during breast conservative surgery (BCS) to provide better hemostasis. The Harmonic scalpel has recently gained momentum as an effective tool for intraoperative bleeding redu...

    Authors: Islam Khaled, Ihab Saad, Hany Soliman and Mohammed Faisal

    Citation: World Journal of Surgical Oncology 2021 19:325

    Content type: Research

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  49. In the Response Evaluation Criteria for Solid Tumors (RECIST) diagnostic criteria, the concepts of progression by preexisting disease (PPL) and progression by new metastases (PNM) have been proposed to disting...

    Authors: Tamami Morisaki, Shinichiro Kashiwagi, Yuka Asano, Wataru Goto, Koji Takada, Sae Ishihara, Masatsune Shibutani, Hiroaki Tanaka, Kosei Hirakawa and Masaichi Ohira

    Citation: World Journal of Surgical Oncology 2021 19:324

    Content type: Research

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  50. Endobronchial metastasis is a very rare type of recurrence after lung cancer surgery. Surgical intervention may be difficult to perform due to the postoperative reduction in the activities of daily living (ADL...

    Authors: Atsushi Ito, Daisuke Yamaguchi, Shinji Kaneda, Koji Kawaguchi, Akira Shimamoto, Makiko Kubooka, Yoshihito Nomoto and Motoshi Takao

    Citation: World Journal of Surgical Oncology 2021 19:322

    Content type: Case report

    Published on:

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