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  1. Metaplastic breast cancer remains poorly characterized given its rarity and heterogeneity. The majority of metaplastic breast cancers demonstrate a phenotype of triple-negative breast cancer; however, differen...

    Authors: Evan Morgan, Anupama Suresh, Akaansha Ganju, Daniel G. Stover, Robert Wesolowski, Sagar Sardesai, Anne Noonan, Raquel Reinbolt, Jeffrey VanDeusen, Nicole Williams, Mathew A. Cherian, Zaibo Li, Gregory Young, Marilly Palettas, Julie Stephens, Joseph Liu…

    Citation: World Journal of Surgical Oncology 2020 18:11

    Content type: Research

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  2. Colorectal peritoneal metastases (CPM) occur in up to 13% of patients with colorectal cancer, presenting either synchronously or metachronously. Cytoreductive surgery and hyperthermic intraperitoneal chemother...

    Authors: Jolene Si Min Wong, Grace Hwei Ching Tan, Claramae Shulyn Chia, Johnny Ong, Wai Yee Ng and Melissa Ching Ching Teo

    Citation: World Journal of Surgical Oncology 2020 18:10

    Content type: Research

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  3. Data reporting the use of modified facelift incision (MFI) approach with or without superficial musculoaponeurotic system (SMAS) reconstruction in parotid malignancy are limited. To enhance the limited knowled...

    Authors: Evangelos I. Giotakis and Aris I. Giotakis

    Citation: World Journal of Surgical Oncology 2020 18:8

    Content type: Research

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  4. Ex situ liver resection and autotransplantation is among the most advanced techniques which has been introduced in recent years.

    Authors: Hesameddin Eghlimi, Peyman Arasteh, Alireza Shamsaeefar, Hamed Nikopour, Sahar Sohrabi and Saman Nikeghbalian

    Citation: World Journal of Surgical Oncology 2020 18:7

    Content type: Case report

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  5. Acral and mucosal melanomas are rarely seen in Caucasians but common in China. There are limited data on the recurrence characteristics for these patients. This study aimed to identify the recurrence pattern f...

    Authors: Xizhi Wen, Dandan Li, Jingjing Zhao, Jingjing Li, Tao Yang, Ya Ding, Ruiqing Peng, Baoyan Zhu, Fuxue Huang and Xiaoshi Zhang

    Citation: World Journal of Surgical Oncology 2020 18:6

    Content type: Research

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  6. The necessity of the inferior pulmonary ligament (IPL) dissection after an upper lobectomy remains controversial. This meta-analysis aimed to evaluate whether this accessional procedure could reduce the postop...

    Authors: Hao Lv, Rui Zhou, Xianghong Zhan, Dongmei Di, Yongxian Qian and Xiaoying Zhang

    Citation: World Journal of Surgical Oncology 2020 18:5

    Content type: Research

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  7. The purpose of this meta-analysis is to compare the safety and efficacy of en bloc transurethral resection of bladder tumor (EBRT) versus conventional transurethral resection of bladder tumor (CTURBT).

    Authors: Dong Zhang, Lifeng Yao, Sui Yu, Yue Cheng, Junhui Jiang, Qi Ma and Zejun Yan

    Citation: World Journal of Surgical Oncology 2020 18:4

    Content type: Review

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  8. Radical resection is the only curative treatment for patients with hilar cholangiocarcinoma. While left-side hepatectomy (LH) may have an oncological disadvantage over right-side hepatectomy (RH) owing to the ...

    Authors: Hye-Sung Jo, Dong-Sik Kim, Young-Dong Yu, Woo-Hyoung Kang and Kyung Chul Yoon

    Citation: World Journal of Surgical Oncology 2020 18:3

    Content type: Research

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  9. The status of lymph nodes in early gastric cancer is critical to make further clinical treatment decision, but the prediction of lymph node metastasis remains difficult before operation. This study aimed to de...

    Authors: Xiao-Yi Yin, Tao Pang, Yu Liu, Hang-Tian Cui, Tian-Hang Luo, Zheng-Mao Lu, Xu-Chao Xue and Guo-En Fang

    Citation: World Journal of Surgical Oncology 2020 18:2

    Content type: Research

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  10. Pancreatic adenocarcinoma is a highly lethal malignancy. Neoadjuvant chemo(radio)therapy [NAC(R)T] is recommended to use for borderline resectable pancreatic cancer (BRPC) and high-risk resectable pancreatic c...

    Authors: Long Pan, Jing Fang, Chenhao Tong, Mingyu Chen, Bin Zhang, Sarun Juengpanich, Yifan Wang and Xiujun Cai

    Citation: World Journal of Surgical Oncology 2019 18:1

    Content type: Research

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  11. The management of infectious complications is important in pancreatoduodenectomy (PD). We sought to determine the significance of preoperative surveillance bile culture in perioperative management of PD.

    Authors: Keishi Sugimachi, Tomohiro Iguchi, Yohei Mano, Masaru Morita, Masaki Mori and Yasushi Toh

    Citation: World Journal of Surgical Oncology 2019 17:232

    Content type: Research

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  12. The rabbit squamous cell cancer line, VX2, has been used to generate various tumor models in rabbits. It is notable for its ability to generate nodal metastases. However, the timing and extent of nodal metasta...

    Authors: Alexander Gregor, Kosuke Fujino, Nicholas Bernards, Tomonari Kinoshita, Yamato Motooka, Terunaga Inage, Tsukasa Ishiwata, Zhenchian Chen, Hideki Ujiie, Chang Young Lee and Kazuhiro Yasufuku

    Citation: World Journal of Surgical Oncology 2019 17:231

    Content type: Technical innovations

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  13. Urinary system resections are performed during the cytoreductive surgery with hypertermic intraperitoneal chemotherapy (CRS-HIPEC). However, isolated ureter resection and reconstruction results are uncertain. ...

    Authors: Şevket Barış Morkavuk, Murat Güner, Mesut Tez and Ali Ekrem Ünal

    Citation: World Journal of Surgical Oncology 2019 17:230

    Content type: Research

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  14. Advanced hepatocellular carcinoma (HCC) with macrovascular invasion has an extremely dismal prognosis. We report a rare case of multiple HCC with tumor thrombosis in the portal vein and inferior vena cava that...

    Authors: Shusei Sano, Shinji Nakata, Shuichi Wada, Masatsugu Kuroiwa, Hiroki Sakai, Kei Kusama, Taiichi Machida, Akihito Nishio, Ichiro Ito and Harutsugu Sodeyama

    Citation: World Journal of Surgical Oncology 2019 17:229

    Content type: Case report

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  15. Approximately 25% of patients with colorectal cancer (CRC) will have liver metastases classified as synchronous or metachronous. There is no consensus on the defining time point for synchronous/metachronous, a...

    Authors: Jennie Engstrand, Cecilia Strömberg, Henrik Nilsson, Jacob Freedman and Eduard Jonas

    Citation: World Journal of Surgical Oncology 2019 17:228

    Content type: Research

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  16. Invasion of the superior vena cava (SVC) by thoracic tumors and occurrence of SVC syndrome are often encountered in clinical practice; but the prognosis in these cases is poor. Replacement of the SVC with auto...

    Authors: Sicong Jiang, Hao Hu, Changying Guo, Feng Jiang, Xi Liu, Lang Tang, Jianjun Tang and Xiaoliang Cheng

    Citation: World Journal of Surgical Oncology 2019 17:227

    Content type: Research

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  17. Perineal wound complications are a long-lasting issue for abdominoperineal resection (APR) patients. Complication rates as high as 60% have been reported, with the most common complication being delayed perine...

    Authors: Chu-Cheng Chang, Yuan-Tzu Lan, Jeng-Kai Jiang, Shih-Ching Chang, Shung-Haur Yang, Chun-Chi Lin, Hung-Hsin Lin, Huann-Sheng Wang, Wei-Shone Chen, Tzu-Chen Lin and Jen-Kou Lin

    Citation: World Journal of Surgical Oncology 2019 17:226

    Content type: Research

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  18. Pelvic lymphadenectomy (PLND) is an integral part of curative surgery for high-risk non-muscle invasive and muscle-invasive bladder cancer. The therapeutic value of extended PLND is controversial.

    Authors: Yu-Chen Wang, Jie Wu, Bo Dai, Yi-Jun Shen, Chun-Guang Ma, Ding-Wei Ye and Yi-Ping Zhu

    Citation: World Journal of Surgical Oncology 2019 17:225

    Content type: Research

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  19. CREB-binding protein (CBP) and p300 represent histone acetyltransferases (HATs) and transcriptional coactivators that play essential roles in tumour initiation and progression. Both proteins are generally thou...

    Authors: Felix Rühlmann, Indra Maria Windhof-Jaidhauser, Cornelius Menze, Tim Beißbarth, Hanibal Bohnenberger, Michael Ghadimi and Sebastian Dango

    Citation: World Journal of Surgical Oncology 2019 17:224

    Content type: Research

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  20. The biological behavior of early recurrence is more invasive and the prognosis is worse in gastric cancer (GC). The risk of early recurrence (ER) for GC in stage II/III has not been reported of which the major...

    Authors: Min Ma, Haifan Xiao, Liang Li, Xianli Yin, Huijun Zhou, Hu Quan, Yongzhong Ouyang, Gang Huang, Xiaorong Li and Hua Xiao

    Citation: World Journal of Surgical Oncology 2019 17:223

    Content type: Research

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  21. Neoadjuvant concurrent chemoradiotherapy (nCCRT) is one of the standard-of-care options for locally advanced esophageal squamous cell carcinoma (LA-ESqCC). The optimal interval between nCCRT and esophagectomy ...

    Authors: Yao-Hung Kuo, Yu-Wen Chien, Pin-Ru Chen, Chun-Lung Feng, Chia-Chin Li and Chun-Ru Chien

    Citation: World Journal of Surgical Oncology 2019 17:222

    Content type: Research

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  22. The morbidity of thyroid carcinoma has been rising worldwide and increasing faster than any other cancer type. The most common subtype with the best prognosis is papillary thyroid cancer (PTC); however, the ex...

    Authors: Cong Zhang, Chunrui Bo, Lunhua Guo, Pingyang Yu, Susheng Miao and Xin Gu

    Citation: World Journal of Surgical Oncology 2019 17:221

    Content type: Research

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  23. To describe the pathological distribution, imaging manifestations, and surgical managements and prognosis of large adrenal tumors (LATs) ≥ 5 cm

    Authors: Zongzong Zhang, Lina Wang, Jing Chen, Xiunan Li, Dikuan Liu, Tianyu Cao, Xuehan Yang, Hongwei Huang, Xuejian Wang, Xishuang Song, Deyong Yang and Jianbo Wang

    Citation: World Journal of Surgical Oncology 2019 17:220

    Content type: Research

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  24. Tumor escape mechanisms mediated in the tumor microenvironment can significantly reduce the capacity of the anti-tumor function of the immune system. TIE2-expressing monocytes (TEMs), related angiopoietins, an...

    Authors: Georgi Atanasov, Karoline Dino, Katrin Schierle, Corinna Dietel, Gabriela Aust, Johann Pratschke, Daniel Seehofer, Moritz Schmelzle and Hans-Michael Hau

    Citation: World Journal of Surgical Oncology 2019 17:217

    Content type: Research

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  25. Associations between polymorphisms in vitamin D receptor (VDR)/vascular endothelial growth factor (VEGF)/interleukin-18 (IL-18)/mannose-binding lectin (MBL) and susceptibility to hepatocellular carcinoma (HCC)...

    Authors: Yi Quan, Jun Yang, Tao Qin and Yufang Hu

    Citation: World Journal of Surgical Oncology 2019 17:216

    Content type: Research

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  26. Peritoneal metastasis (PM) is one of the most common forms of metastasis with a very poor prognosis in patients with gastric cancer (GC). The mechanisms, diagnosis, and management of PM remain controversial.

    Authors: Zhen Wang, Jun-qiang Chen, Jin-lu Liu and Lei Tian

    Citation: World Journal of Surgical Oncology 2019 17:215

    Content type: Review

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  27. This study aimed to evaluate the clinical outcomes of concurrent liver resection with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in colorectal cancer patients with synchronous liver an...

    Authors: Youngbae Jeon, Eun Jung Park, Jin Hong Lim and Seung Hyuk Baik

    Citation: World Journal of Surgical Oncology 2019 17:214

    Content type: Research

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  28. Zollinger-Ellison syndrome (ZES) is a rare condition characterized by hypersecretion of gastrin by gastrinoma tumors leading to severe peptic ulcer disease with potential development of gastric carcinoid tumor...

    Authors: Lynsey M. Daniels, Marian Khalili, William F. Morano, Michaela Simoncini, Beth C. Mapow, Andrea Leaf and Wilbur B. Bowne

    Citation: World Journal of Surgical Oncology 2019 17:213

    Content type: Case report

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  29. Local excision (LE) is a feasible treatment approach for rectal cancers in stage pT1 and presents low pathological risk, whereas total mesorectal excision (TME) is a reasonable treatment for more advanced canc...

    Authors: I-Li Lai, Jeng-Fu You, Yih-Jong Chern, Wen-Sy Tsai, Jy-Ming Chiang, Pao-Shiu Hsieh, Hsin-Yuan Hung, Chien-Yuh Yeh, Sum-Fu Chiang, Cheng-Chou Lai, Rei-Ping Tang, Jinn-Shiun Chen and Yu-Jen Hsu

    Citation: World Journal of Surgical Oncology 2019 17:212

    Content type: Research

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  30. High-grade dysplasia/carcinoma in situ (HGD/CIS) of the biliary duct margin was found to not affect the prognosis of patients with extrahepatic cholangiocarcinoma by recent studies, but it has not yet reached ...

    Authors: Qiao Ke, Bin Wang, Nanping Lin, Lei Wang and Jingfeng Liu

    Citation: World Journal of Surgical Oncology 2019 17:211

    Content type: Review

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  31. The evaluation of thyroid nodules with ultrasonography has created a large burden for radiologists. Artificial intelligence technology has been rapidly developed in recent years to reduce the cost of labor and...

    Authors: Shujun Xia, Jiejie Yao, Wei Zhou, Yijie Dong, Shangyan Xu, Jianqiao Zhou and Weiwei Zhan

    Citation: World Journal of Surgical Oncology 2019 17:210

    Content type: Research

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  32. The incidence of adenocarcinoma of esophagogastric junction (AEG) has recently risen worldwide, including in Eastern Asia. The aim of the study was to explore the short-term and long-term clinical efficacy of ...

    Authors: Zhiguo Li, Jianhong Dong, Qingxing Huang, Wanhong Zhang and Kai Tao

    Citation: World Journal of Surgical Oncology 2019 17:209

    Content type: Research

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  33. Ultrasound, along with ultrasound-guided fine needle aspiration, is currently used for the axillary evaluation of breast cancer patients in order to identify candidates for axillary lymph node dissection. The ...

    Authors: Michel Attieh, Faek Jamali, Ghina Berjawi, Mothana Saadeldine and Fouad Boulos

    Citation: World Journal of Surgical Oncology 2019 17:208

    Content type: Research

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  34. We evaluated clinicopathological changes of breast cancer (BC) during a 22-year time period among the Iranian population.

    Authors: Sedigheh Tahmasebi, Mahsa Tajali, Majid Akrami, Peyman Arasteh, Vahid Zangouri, Aida Salehi Nobandegani, Seyed Morteza Hosseini, Afsoon Safari and Abdolrasoul Talei

    Citation: World Journal of Surgical Oncology 2019 17:207

    Content type: Research

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  35. Malignant transformation of endometriosis in the rectovaginal septum is rare and usually misdiagnosed as a colorectal or gynecological tumor. We report a rare case of primary endometrioid adenocarcinoma of the...

    Authors: Hua Yang, Jiao-jiao Gu, Yue Qi, Wei Zhao and Xin-lu Wang

    Citation: World Journal of Surgical Oncology 2019 17:206

    Content type: Case report

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  36. Growing evidence supports the role of the intestinal microbiome in the carcinogenesis of colorectal cancers, but its impact on colorectal cancer surgery outcomes is not clearly defined. This systematic review ...

    Authors: Lelde Lauka, Elisa Reitano, Maria Clotilde Carra, Federica Gaiani, Paschalis Gavriilidis, Francesco Brunetti, Gian Luigi de’Angelis, Iradj Sobhani and Nicola de’Angelis

    Citation: World Journal of Surgical Oncology 2019 17:204

    Content type: Review

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  37. Survival rate of patients treated for gastric cancer has increased due to early detection and improvements of surgical technique and chemotherapy. Increase in survival rate has led to an increase in the risk f...

    Authors: Yong-Eun Park and Sang-Woon Kim

    Citation: World Journal of Surgical Oncology 2019 17:203

    Content type: Research

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  38. Glove single-port laparoscopy-assisted transanal total mesorectal excision (TaTME) has been successfully carried out in our medical center. The purpose of this study is to evaluate the feasibility of this emer...

    Authors: Wanglin Li, Boye Dong, Baifu Peng, Jiabao Lu, Zixin Wu, Guanwei Li and Jie Cao

    Citation: World Journal of Surgical Oncology 2019 17:202

    Content type: Technical innovations

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  39. Gastric cancer (GC) remains one of the leading causes of cancer-related death. Arteriointestinal fistula is a very rare but lethal postoperative complication in GC patients after gastrectomy. However, very few...

    Authors: Liang Chen, Xuezhi Ming, Rongmin Gu, Xu Wen, Gang Li, Bin Zhou, Wei Wei and Huanqiu Chen

    Citation: World Journal of Surgical Oncology 2019 17:201

    Content type: Research

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  40. The indications for extrahepatic bile duct (EHBD) resection remain a major controversy in the surgical management of patients with gallbladder cancer. On the other hand, perineural invasion (PNI) was reported ...

    Authors: Suguru Maruyama, Hiromichi Kawaida, Naohiro Hosomura, Hidetake Amemiya, Ryo Saito, Hiroki Shimizu, Shinji Furuya, Hidenori Akaike, Yoshihiko Kawaguchi, Makoto Sudo, Shingo Inoue, Hiroshi Kono and Daisuke Ichikawa

    Citation: World Journal of Surgical Oncology 2019 17:200

    Content type: Research

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  41. Colorectal cancer is the fourth most common cancer globally and neoadjuvant concurrent chemoradiotherapy (nCRT) and surgery are the standard treatments for locally advanced colorectal carcinoma. This study inv...

    Authors: Hongen Xu, Guangxian You, Minjun Zhang, Tao Song, Haibo Zhang, Jia Yang, Yongshi Jia, Jianming Tang and Xiaodong Liang

    Citation: World Journal of Surgical Oncology 2019 17:199

    Content type: Research

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  42. In Japan, the majority of gastrointestinal tract neuroendocrine tumors (NETs) have been reported to originate from the rectum, and appendiceal NETs are relatively rare. Preoperative diagnosis is very difficult...

    Authors: Ayana Goto, Nobuhisa Matsuhashi, Takao Takahashi, Yuta Sato, Shinya Hirata, Toshiyuki Tanahashi, Satoshi Matsui, Hisasi Imai, Yoshihiro Tanaka, Kazuya Yamaguchi and Kazuhiro Yoshida

    Citation: World Journal of Surgical Oncology 2019 17:197

    Content type: Case report

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  43. To evaluate the feasibility and safety of ultrasound-guided totally implantable venous access port (TIVAP) implantation via the right innominate vein in patients with breast cancer.

    Authors: Liang Xu, Wenming Qin, Weiwei Zheng and Xingwei Sun

    Citation: World Journal of Surgical Oncology 2019 17:196

    Content type: Technical innovations

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  44. Although it is known that portomesenteric venous thrombosis (PMVT) is associated with total colectomy and proctocolectomy in young patients with inflammatory bowel disease, little is known about incidence and ...

    Authors: Michele Manigrasso, Marco Milone, Nunzio Velotti, Sara Vertaldi, Pietro Schettino, Mario Musella, Giovanni Aprea, Nicola Gennarelli, Francesco Maione, Giovanni Sarnelli, Pietro Venetucci, Giovanni Domenico De Palma and Francesco Milone

    Citation: World Journal of Surgical Oncology 2019 17:195

    Content type: Research

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  45. Revised Tokuhashi score (RTS) is no longer accurate to predict the survival of patients with lung cancer metastases to the spine. This study is to identify additional prognostic factors in those patients, deve...

    Authors: Zhenyu Cai, Xiaodong Tang, Rongli Yang, Taiqiang Yan and Wei Guo

    Citation: World Journal of Surgical Oncology 2019 17:194

    Content type: Research

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