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  1. The effect of antiviral therapy (AVT) on clinical outcomes in patients with hepatocellular carcinoma (HCC) who are seronegative for hepatitis B virus (HBV), defined as HBV DNA < 100 IU/ml prior to surgical res...

    Authors: Mingxing Xu, Zheng Zhou, Ruiyun Xu, Huiling Zhang, Nan Lin and Yuesi Zhong

    Citation: World Journal of Surgical Oncology 2019 17:45

    Content type: Research

    Published on:

  2. The purpose of this study was to explore trends in incidence, incidence-based (IB) mortality, and survival for combined hepatocellular-cholangiocarcinoma (cHCC-CC) utilizing a population-based database to attr...

    Authors: Jiakun Wang, Enliang Li, Hao Yang, Junjun Wu, Hong cheng Lu, Chenhao Yi, Jun Lei, Wenjun Liao and Linquan Wu

    Citation: World Journal of Surgical Oncology 2019 17:43

    Content type: Research

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  3. The giant multilocular prostatic cystadenoma is a very rare benign tumor of the prostate gland. It is composed of predominantly cystic enlarged prostatic glands in a fibrous stroma and spreads extensively into...

    Authors: Yuya Nakamura, Dai Shida, Takahiro Shibayama, Akihiko Yoshida, Yoshiyuki Matsui, Yasuo Shinoda, Shintaro Iwata and Yukihide Kanemitsu

    Citation: World Journal of Surgical Oncology 2019 17:42

    Content type: Case report

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  4. The prognostic value of sentinel lymph node (SLN) metastases may be minimized by the limited disease burden of lymph node metastases and tailoring adjuvant therapy based on breast cancer biology. The aim of th...

    Authors: Hideo Shigematsu, Mai Nishina, Daisuke Yasui, Taizo Hirata and Shinji Ozaki

    Citation: World Journal of Surgical Oncology 2019 17:41

    Content type: Research

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  5. Chest computed tomography (CTC) has now replaced chest X-ray (CXR) as the first choice of investigation to stage breast cancers in most centers in Australia. Routine staging is not recommended in early breast ...

    Authors: Justin James, Melanie Teo, Vivekananda Ramachandran, Michael Law, David Stoney and Michael Cheng

    Citation: World Journal of Surgical Oncology 2019 17:40

    Content type: Research

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  6. Prediction of nodal involvement in colorectal cancer is an important aspect of preoperative workup to determine the necessity of preoperative treatment and the adequate extent of lymphadenectomy during surgery...

    Authors: Tsutomu Kumamoto, Junichi Shindoh, Hideaki Mita, Yuriko Fujii, Yuichiro Mihara, Michiro Takahashi, Nobuyuki Takemura, Takako Shirakawa, Hisashi Shinohara and Hiroya Kuroyanagi

    Citation: World Journal of Surgical Oncology 2019 17:39

    Content type: Research

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  7. Retroperitoneal laparoscopic radical and partial nephrectomy (RLRN and RLPN) have become the preferred modes of management for renal malignancy. One of the most critical steps in the RLRN and RLPN process is t...

    Authors: Feiya Yang, Qiang Zhou, Xuesong Li and Nianzeng Xing

    Citation: World Journal of Surgical Oncology 2019 17:38

    Content type: Technical innovations

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  8. Breast cancer patients with suspicious axillary lymph node (ALN) at ultrasound and positive fine-needle aspiration (FNA) results were required to receive ALN dissection (ALND), which was not certain in the pos...

    Authors: Yue Liang, Xiaosong Chen, Yiwei Tong, Weiwei Zhan, Ying Zhu, Jiayi Wu, Ou Huang, Jianrong He, Li Zhu, Yafen Li, Weiguo Chen and Kunwei Shen

    Citation: World Journal of Surgical Oncology 2019 17:37

    Content type: Research

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  9. Retroperitoneal tumors are an uncommon disease known to consist of a diverse group of benign and malignant neoplasms. Treatment of unresectable retroperitoneal lesions requires pathological diagnosis. Here, we...

    Authors: Makito Miyake, Shinji Fukui, Daisuke Gotoh, Yoshiaki Matsumura, Shoji Samma, Yoshihiro Matsumoto, Hitoshi Momose, Shunta Hori, Shuji Watanabe, Takuya Owari, Yosuke Morizawa, Yoshitaka Itami, Yasushi Nakai, Takeshi Inoue, Satoshi Anai, Kazumasa Torimoto…

    Citation: World Journal of Surgical Oncology 2019 17:35

    Content type: Research

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  10. Pseudomyxoma peritonei (PMP) is an uncommon condition characterized by diffuse mucinous material in the abdomen and pelvis, generally arising from a perforated epithelial neoplasm. Typically, the disease prese...

    Authors: Brianne J. Sullivan, Nathan Bolton, Umut Sarpel and Deepa Magge

    Citation: World Journal of Surgical Oncology 2019 17:34

    Content type: Case report

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  11. Although hepatectomy for metastatic colorectal cancer (mCRC) prolongs survival in up to 40% of people, recurrence rates approach 70%. We used a multidisciplinary approach to treat recurrent liver metastases, i...

    Authors: Hiroshi Matsuoka, Zenichi Morise, Chihiro Tanaka, Takahiro Hayashi, Yoshiaki Ikeda, Koutarou Maeda, Koji Masumori, Yoshikazu Koide, Hidetoshi Katsuno, Yoshinao Tanahashi, Sanae Nakajima, Tsunekazu Hanai, Yutaro Kato, Atsushi Sugioka and Ichiro Uyama

    Citation: World Journal of Surgical Oncology 2019 17:33

    Content type: Research

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  12. Endoscopic resection (ER) has come to be recognized as a standard treatment for early gastric cancer (EGC). While its adoption is expanding, ER remains restricted to cases of EGC without lymph node metastasis ...

    Authors: Rieko Nakamura, Tai Omori, Shuhei Mayanagi, Tomoyuki Irino, Norihito Wada, Hirofumi Kawakubo, Kaori Kameyama and Yuko Kitagawa

    Citation: World Journal of Surgical Oncology 2019 17:32

    Content type: Research

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  13. Because conventional prostate biopsy has some limitations, optimal variations of prostate biopsy strategies have emerged to improve the diagnosis rate of prostate cancer. We conducted the systematic review to ...

    Authors: Jianjian Xiang, Huaqing Yan, Jiangfeng Li, Xiao Wang, Hong Chen and Xiangyi Zheng

    Citation: World Journal of Surgical Oncology 2019 17:31

    Content type: Review

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  14. Oncostatin M receptor (OSMR) represents a part of the interleukin-six (IL6) cytokine group that was discovered recently to be closely associated with cell’s growth and differentiation, inflammation, and enhanceme...

    Authors: Shi Deng, Sheng yin He, Pan Zhao and Peng Zhang

    Citation: World Journal of Surgical Oncology 2019 17:30

    Content type: Research

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  15. Pancreatic ductal adenocarcinoma (PDAC) is characterized by an extremely dense stroma, which has a fundamental role in tumor progression. Fibronectin (FN1) is the main constituent of the tumor stroma in pancre...

    Authors: Dingyuan Hu, Daniel Ansari, Qimin Zhou, Agata Sasor, Katarzyna Said Hilmersson and Roland Andersson

    Citation: World Journal of Surgical Oncology 2019 17:29

    Content type: Research

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  16. The optimal extent of lymph node (LN) dissection for advanced distal gastric cancer remains controversial. The present study compared the safety and efficacy of extended LN dissection (D2 plus) with standard D...

    Authors: Pengfei Yu, Yian Du, Zhiyuan Xu, Ling Huang and Xiangdong Cheng

    Citation: World Journal of Surgical Oncology 2019 17:28

    Content type: Research

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  17. Few studies of robotic nipple sparing mastectomy (NSM) were reported. We report feasibility of robotic NSM and determine standard surgical procedure and learning curve threefold.

    Authors: G. Houvenaeghel, M. Bannier, S. Rua, J. Barrou, M. Heinemann, A. Van Troy, E. Lambaudie and M. Cohen

    Citation: World Journal of Surgical Oncology 2019 17:27

    Content type: Research

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  18. Reoperation following PD is a surrogate marker for a complex post-operative course and may lead to devastating consequences. We evaluate the indications for early reoperation following PD and analyze its effec...

    Authors: Yonatan Lessing, Niv Pencovich, Nadav Nevo, Nir Lubezky, Yaacov Goykhman, Richard Nakache, Guy Lahat, Joseph M. Klausner and Ido Nachmany

    Citation: World Journal of Surgical Oncology 2019 17:26

    Content type: Research

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  19. The abnormal expression of activator protein-1(AP-1) has recently been investigated in a variety of tumors. While the relationship between AP-1 and thyroid cancer is poorly studied, our study was to evaluate t...

    Authors: Cheng Xiao, Yonglian Huang, Qiyuan Gao, Zijian Feng, Qi Li and Zhen Liu

    Citation: World Journal of Surgical Oncology 2019 17:25

    Content type: Research

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  20. Endometrioid ovarian carcinoma and clear cell ovarian carcinoma are both classified as endometriosis-associated ovarian cancers (EAOCs). Despite the high rates of recurrence and mortality of EAOC, only a few p...

    Authors: Tsukuru Amano, Tokuhiro Chano, Takahiro Isono, Fuminori Kimura, Ryoji Kushima and Takashi Murakami

    Citation: World Journal of Surgical Oncology 2019 17:24

    Content type: Research

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  21. Osteosarcoma is a malignant bone tumor with a high potential for lung metastasis, and the prognosis for patients with metastatic disease is very poor. The interaction between fibronectin (FN) and integrin αvβ3...

    Authors: Kai Shi, Sheng-lin Wang, Bin Shen, Feng-qiang Yu, Dan-feng Weng and Jian-hua Lin

    Citation: World Journal of Surgical Oncology 2019 17:23

    Content type: Research

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  22. Congenital intracranial tumors are very rare and account for less than 2% of all childhood brain tumors. Teratomas constitute about one third to one half of these, predominantly located midline in the supraten...

    Authors: Yazid Maghrabi, Maher E. Kurdi and Saleh S. Baeesa

    Citation: World Journal of Surgical Oncology 2019 17:22

    Content type: Case report

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  23. Bowel obstruction (BO) is a complication that commonly affects patients with colorectal cancer (CRC). BO causes severe outcomes, and its treatment leads to a dilemma for many surgeons. Moreover, the factors co...

    Authors: Xinger Lv, Hong Yu, Peng Gao, Yongxi Song, Jingxu Sun, Xiaowan Chen, Yu Wang and Zhenning Wang

    Citation: World Journal of Surgical Oncology 2019 17:21

    Content type: Research

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  24. Anastomotic leakage (AL) following colorectal resection is a serious issue. AL in oncologic patients might negatively affect the overall survival. Recently, mechanical bowel preparation with additive oral anti...

    Authors: Peter C. Ambe, Konstantinos Zarras, Maciej Stodolski, Ingfu Wirjawan and Hubert Zirngibl

    Citation: World Journal of Surgical Oncology 2019 17:20

    Content type: Research

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  25. Spontaneous regression (SR) of colorectal cancer (CRC) is extremely rare, and only few cases have been reported. Although it is not yet clarified, a plausible mechanism for SR of CRC is an immunological event.

    Authors: Nozomi Karakuchi, Manabu Shimomura, Kazuhiro Toyota, Takao Hinoi, Hideki Yamamoto, Seiji Sadamoto, Koichi Mandai, Hiroyuki Egi, Hideki Ohdan and Tadateru Takahashi

    Citation: World Journal of Surgical Oncology 2019 17:19

    Content type: Case report

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  26. To define preoperative clinical and radiographic risk factors for the need of inferior vena cava (IVC) resection in patients with renal cell carcinoma (RCC) and IVC tumor thrombus.

    Authors: Bin-Shuai Wang, Run-Zhuo Ma, Yu-Qing Liu, Zhuo Liu, Li-Yuan Tao, Min Lu, Guo-Liang Wang, Shu-Dong Zhang, Jian Lu and Lu-Lin Ma

    Citation: World Journal of Surgical Oncology 2019 17:17

    Content type: Research

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  27. Oral cancer is very common in India. The reported 5-year survival of such patients is around 50% after treatment with surgery and radiotherapy, much lower than most of the developed countries.

    Authors: Sajith Babu Thavarool, Geetha Muttath, Sangeetha Nayanar, Karthickeyan Duraisamy, Prasanth Bhat, Kalpita Shringarpure, Priyakanta Nayak, Jaya Prasad Tripathy, Alfonso Thaddeus, Sairu Philip and Satheesan B

    Citation: World Journal of Surgical Oncology 2019 17:15

    Content type: Research

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  28. Standard treatment for colorectal peritoneal carcinomatosis typically involves cytoreductive surgery, hyperthermic intraperitoneal chemotherapy (HIPEC), and if possible, postoperative adjuvant chemotherapy. Ho...

    Authors: M. Leimkühler, P. H. J. Hemmer, A. K. L. Reyners, D. J. A. de Groot, R. J. van Ginkel, L. B. Been, G. H. de Bock and B. L. van Leeuwen

    Citation: World Journal of Surgical Oncology 2019 17:14

    Content type: Research

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  29. Metastasis of oral cancer to the buccinator lymph nodes (BN) is uncommon. The antegrade lymphatic flow in patients with normal anatomy and physiology makes metastasis of lower gingival cancer to BN unlikely.

    Authors: Kaho Takada, Takeshi Kuroshima, Hiroaki Shimamoto, Toshimitsu Ohsako, Kou Kayamori, Tohru Ikeda and Hiroyuki Harada

    Citation: World Journal of Surgical Oncology 2019 17:13

    Content type: Case report

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  30. In this study, images of 2450 benign thyroid nodules and 2557 malignant thyroid nodules were collected and labeled, and an automatic image recognition and diagnosis system was established by deep learning usin...

    Authors: Lei Wang, Shujian Yang, Shan Yang, Cheng Zhao, Guangye Tian, Yuxiu Gao, Yongjian Chen and Yun Lu

    Citation: World Journal of Surgical Oncology 2019 17:12

    Content type: Research

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  31. Colorectal cancer is the third most common malignancy worldwide. The occurrence of liver metastases worsens the prognosis of the patient significantly if the tumor burden is not resectable.

    Authors: Falk Rauchfuß, Silvio Nadalin, Alfred Königsrainer and Utz Settmacher

    Citation: World Journal of Surgical Oncology 2019 17:11

    Content type: Technical innovations

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  32. Although gout is a common disease, the presence of gouty tophi outside joints is rare and in literature, there is to date only one report of hepatic tophaceous nodule. We would like to highlight here the diffi...

    Authors: S. Ministrini, G. Baronio, F. Zorzi, L. Bercich, L. Grazioli, S. Molfino and N. Portolani

    Citation: World Journal of Surgical Oncology 2019 17:10

    Content type: Case report

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  33. To investigate the mortality, operation time, cystectomy time, and complications of anterior approach laparoscopic radical cystectomy (ALRC) in Asian males in comparison with posterior approach laparoscopic ra...

    Authors: Shiyu Tong, Zhenyu Yang, Xiongbin Zu, Yuan Li, Wei He, Yangle Li, Xiheng Hu, Cheng Zhao, Minfeng Chen and Lin Qi

    Citation: World Journal of Surgical Oncology 2019 17:9

    Content type: Research

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  34. While extended cholecystectomy is recommended for T2 gallbladder cancer (GBC), the role of hepatic resection for T2 GBC is unclear. This study aimed to identify the necessity of hepatic resection in patients w...

    Authors: Jin-Kyu Cho, Woohyung Lee, Jae Yool Jang, Han-Gil Kim, Jae-Myung Kim, Seung-Jin Kwag, Ji-Ho Park, Ju-Yeon Kim, Taejin Park, Sang-Ho Jeong, Young-Tae Ju, Eun-Jung Jung, Young-Joon Lee, Soon-Chan Hong and Chi-Young Jeong

    Citation: World Journal of Surgical Oncology 2019 17:8

    Content type: Research

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  35. Primary pancreatic leiomyosarcoma is an extremely rare entity that needs high clinical suspicion in order to diagnose it at an early stage. Clinical characteristics, diagnosis, and management still remain chal...

    Authors: Alexandros Papalampros, Michail G. Vailas, Ioanna Deladetsima, Demetrios Moris, Maria Sotiropoulou, Athanasios Syllaios, Athanasios Petrou and Evangelos Felekouras

    Citation: World Journal of Surgical Oncology 2019 17:6

    Content type: Case report

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  36. Clinically relevant postoperative pancreatic fistula (CR-POPF) remains the most common neopathy after pancreatoduodenectomy (PD). An ideal pancreaticoenterostomy (PE) which can effectively reduce the incidence...

    Authors: Tianchong Wu, Yuehua Guo, Jiangang Bi, Shuwang Liu, Yusheng Guo and Shiyun Bao

    Citation: World Journal of Surgical Oncology 2019 17:5

    Content type: Research

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  37. Although pathological evaluation has been considered an effective evaluation method, some problems still exist in practice. Therefore, we explored whether there are more reasonable and practical pathological e...

    Authors: Shen-Bao Hu, Chun-Hao Liu, Xiang Wang, Yun-Wei Dong, Lin Zhao, Hong-Feng Liu, Yue Cao, Ding-Rong Zhong, Wei Liu, Yan-Long Li, Wei-Sheng Gao, Chun-Mei Bai, Zhong-Hua Shang and Xiao-Yi Li

    Citation: World Journal of Surgical Oncology 2019 17:3

    Content type: Research

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  38. Most intrahepatic cholangiocarcinoma (ICC) patients experienced tumor recurrences even after curative resection, but the optimal cut-off time point and the specific risk factors for early and late recurrences ...

    Authors: Changzheng Wang, Shujie Pang, Hui Si-Ma, Ning Yang, Haibin Zhang, Yong Fu and Guangshun Yang

    Citation: World Journal of Surgical Oncology 2019 17:2

    Content type: Research

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  39. For hepatocellular carcinoma (HCC), liver resection is a classical curative modality, despite its technical complexity. The incidence of HCC in the oldest old people (aged ≥ 85 years) is rising along with the ...

    Authors: Feng-Hsu Wu, Ching-Hui Shen, Shao-Ciao Luo, Jen-I Hwang, Wen-Shan Chao, Hong-Zen Yeh, Yee-Gee Jan, Yun Yen, Shao-Bin Cheng, Cheng-Chung Wu, Yi-Ling Lin and Fang-Ku P’eng

    Citation: World Journal of Surgical Oncology 2019 17:1

    Content type: Research

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  40. Radiation therapy is an important therapeutic element in musculoskeletal tumours, especially when encountering multiple or painful lesions. In osteolytic lesions, a surgical stabilization with implants is ofte...

    Authors: Christoph J. Laux, Sandro M. Hodel, Mazda Farshad and Daniel A. Müller

    Citation: World Journal of Surgical Oncology 2018 16:241

    Content type: Research

    Published on:

  41. This study aimed to investigate the expression of P90 Ribosomal Protein S6 kinase 4 (RSK4) in colorectal cancer cells and its biological function.

    Authors: Qingqing Ye, Xuan Wang, Min Jin, Meng Wang, Yan Hu, Shihu Yu, Yonghua Yang, Jiyuan Yang and Jun Cai

    Citation: World Journal of Surgical Oncology 2018 16:240

    Content type: Research

    Published on:

  42. To evaluate the intraoperative and short-term postoperative outcomes of a novel robotic intracorporeal π-shaped esophagojejunostomy (EJS) after D2 total gastrectomy (TG) using the Da Vinci robotic surgical system...

    Authors: Shangxin Zhang, Junaid Khaliq, Deguan Li, Xingwang Jiang, Ruochuan Sun and Yongxiang Li

    Citation: World Journal of Surgical Oncology 2018 16:238

    Content type: Technical innovations

    Published on:

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