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  1. Pituitary adenomas are one type of intracranial tumor, which can be divided into microadenoma (≤ 1 cm), macroadenoma (> 1 cm), and giant adenoma (≥ 4 cm) according to their diametral sizes. They are benign, ty...

    Authors: Ding Nie, Qiuyue Fang, Bin Li, Jianhua Cheng, Chuzhong Li, Songbai Gui, Yazhuo Zhang and Peng Zhao

    Citation: World Journal of Surgical Oncology 2021 19:162

    Content type: Review

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  2. Bronchopleural fistula (BPF) refers to an abnormal channel between the pleural space and the bronchial tree. It is a potentially fatal postoperative complication after pulmonary resection and a complex challen...

    Authors: Yongyong Wu, Zhongliang He, Weihua Xu, Guoxing Chen, Zhijun Liu and Ziying Lu

    Citation: World Journal of Surgical Oncology 2021 19:158

    Content type: Case report

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  3. Biologic bone reconstruction in limb salvage surgery for the treatment of malignant bone tumours has always been controversial. The various inactivation methods, their convenience and stability, the curative e...

    Authors: Meitao Xu, Ming Xu, Shuai Zhang, Hanqing Li, A. I. Qiuchi, Xiuchun Yu and Xu Quan Wang

    Citation: World Journal of Surgical Oncology 2021 19:157

    Content type: Research

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  4. Renal cell carcinoma (RCC) is a common malignant tumour of the genitourinary system. We aimed to analyse the potential value of metastasis-related biomarkers, circulating tumour cells (CTCs) and the proliferat...

    Authors: Jinbo Song, Zhe Yu, Bingqi Dong, Mingkai Zhu, Xiaofeng Guo, Yongkang Ma, Shiming Zhao and Tiejun Yang

    Citation: World Journal of Surgical Oncology 2021 19:156

    Content type: Research

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  5. Robot-assisted surgery is increasingly implemented for the resection of colorectal cancer, although the scientific evidence for adopting this technique is still limited. This study’s main objective was to comp...

    Authors: Pedja Cuk, Randi Maria Simonsen, Mirjana Komljen, Michael Festersen Nielsen, Per Helligsø, Andreas Kristian Pedersen, Christian Backer Mogensen and Mark Bremholm Ellebæk

    Citation: World Journal of Surgical Oncology 2021 19:155

    Content type: Research

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  6. The main negative prognostic factors in patients with rectal cancer after radical treatment include regional lymph node involvement, lymphovascular invasion, and perineural invasion. However, some patients sti...

    Authors: Marcin Zeman, Marek Czarnecki, Ewa Chmielik, Adam Idasiak, Władysław Skałba, Mirosław Strączyński, Piotr J. Paul and Agnieszka Czarniecka

    Citation: World Journal of Surgical Oncology 2021 19:154

    Content type: Research

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  7. Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) are effective routine treatments for colorectal peritoneal metastasis (PM). However, the safety and efficacy of neoadjuvant che...

    Authors: Sicheng Zhou, Yujuan Jiang, Jianwei Liang, Wei Pei and Zhixiang Zhou

    Citation: World Journal of Surgical Oncology 2021 19:151

    Content type: Research

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  8. Approximately 20% of patients with colorectal cancer are initially diagnosed with stage IV disease. This study aims to examine the role of regional lymph node (LN) status in metastatic colorectal cancer (mCRC)...

    Authors: Ya-Ting Kuo, Wen-Sy Tsai, Hsin-Yuan Hung, Pao-Shiu Hsieh, Sum-Fu Chiang, Cheng-Chou Lai, Yih-Jong Chern, Yu-Jen Hsu and Jeng-Fu You

    Citation: World Journal of Surgical Oncology 2021 19:150

    Content type: Research

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  9. The aim of this study was to compare conventional suture with prolonged timing of drainage with quilting suture on the formation of seroma at pectoral area after mastectomy (ME) with sentinel lymph node biopsy...

    Authors: Juan Huang, Shouman Wang, Yuhui Wu, Jian Hai, Jie Mao, Xue Dong and Zhi Xiao

    Citation: World Journal of Surgical Oncology 2021 19:148

    Content type: Research

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  10. Radiomics methods are used to analyze various medical images, including computed tomography (CT), magnetic resonance, and positron emission tomography to provide information regarding the diagnosis, patient ou...

    Authors: Ayten Kayi Cangir, Kaan Orhan, Yusuf Kahya, Hilal Özakıncı, Betül Bahar Kazak, Buse Mine Konuk Balcı, Duru Karasoy and Çağlar Uzun

    Citation: World Journal of Surgical Oncology 2021 19:147

    Content type: Research

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  11. To investigate the predictive value of programmed death-ligand 1 (PD-L1) expression in non-small cell lung cancer (NSCLC) patients treated with epidermal growth factor receptor tyrosine kinase inhibitors (EGFR...

    Authors: Zhiyu Peng, Huahang Lin, Ke Zhou, Senyi Deng and Jiandong Mei

    Citation: World Journal of Surgical Oncology 2021 19:145

    Content type: Review

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  12. Lipoleiomyoma is a rare, benign variant of the commonplace uterine leiomyoma. Unlike leiomyoma, these tumors are composed of smooth muscle cells admixed with mature adipose tissue. While rare, they are most fr...

    Authors: Sara L. Schaefer, Amy L. Strong, Sheena Bahroloomi, Jichang Han, Michella K. Whisman, Jodi M. Wilkowski and Christina V. Angeles

    Citation: World Journal of Surgical Oncology 2021 19:144

    Content type: Case report

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  13. Thyroid neoplasms with follicular architecture can have overlapping morphologic features and pose diagnostic confusion among pathologists. Various immunohistochemical stains have been investigated as potential...

    Authors: Qandeel Sadiq, Radhika Sekhri, Daniel T. Dibaba, Qi Zhao and Shweta Agarwal

    Citation: World Journal of Surgical Oncology 2021 19:143

    Content type: Research

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  14. No universal classification method for intrahepatic cholangiocarcinoma (IHCC) has been reported based on the embryological origin of biliary epithelial cells. The aim of this study was to classify IHCC accordi...

    Authors: Shoko Yamashita, Yuji Morine, Satoru Imura, Tetsuya Ikemoto, Yu Saito, Chie Takasu, Shinichiro Yamada, Kazunori Tokuda, Shohei Okikawa, Katsuki Miyazaki, Takeshi Oya, Koichi Tsuneyama and Mitsuo Shimada

    Citation: World Journal of Surgical Oncology 2021 19:142

    Content type: Research

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  15. With the advent of more intensive chemotherapy regimens, neoadjuvant chemoradiotherapy (NACRT) for patients with locally advanced rectal cancer (LARC) has always been questioned due to its inevitable radiation...

    Authors: Huaqin Lin, Lei Wang, Xiaohong Zhong, Xueqing Zhang, Lingdong Shao and Junxin Wu

    Citation: World Journal of Surgical Oncology 2021 19:141

    Content type: Review

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  16. Treatments for metastatic fracture of the humeral shaft continue to evolve as advances are made in both oncological and operative management. The purposes of this study were to critically evaluate the effectiv...

    Authors: Zhiqing Zhao, Zhipeng Ye, Taiqiang Yan, Xiaodong Tang, Wei Guo and Rongli Yang

    Citation: World Journal of Surgical Oncology 2021 19:140

    Content type: Research

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  17. The inflammatory biomarker “C-reactive protein to albumin ratio (CAR)” has been reported to significantly correlate to a variety of human cancers. However, there are conflicting results regarding the prognosti...

    Authors: Chun-Kai Liao, Yen-Lin Yu, Yueh-Chen Lin, Yu-Jen Hsu, Yih-Jong Chern, Jy-Ming Chiang and Jeng-Fu You

    Citation: World Journal of Surgical Oncology 2021 19:139

    Content type: Review

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  18. Mesenchymal sarcomas are tumors that originate from mesenchymal tissue. Most mesenchymal sarcomas can be accurately classified, but some are unclassifiable in clinical practice. Molecular detection methods ena...

    Authors: Weijie Chen, Huimei Wang, Dongxian Jiang, Lijuan Luan, Yuhong Zhou and Yingyong Hou

    Citation: World Journal of Surgical Oncology 2021 19:136

    Content type: Case report

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  19. The prognosis of colon cancer (CC) is challenging to predict due to its highly heterogeneous nature. Ferroptosis, an iron-dependent form of cell death, has roles in various cancers; however, the correlation be...

    Authors: Ye Wang, Heng-bo Xia, Zhang-ming Chen, Lei Meng and A-man Xu

    Citation: World Journal of Surgical Oncology 2021 19:135

    Content type: Research

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  20. Medulloblastoma (MB) is the most common pediatric embryonal tumor. Accurate identification of cerebral spinal fluid (CSF) dissemination is important in prognosis prediction. Both MRI of the central nervous sys...

    Authors: Hui Zheng, Jinning Li, Huanhuan Liu, Chenqing Wu, Ting Gui, Ming Liu, Yuzhen Zhang, Shaofeng Duan, Yuhua Li and Dengbin Wang

    Citation: World Journal of Surgical Oncology 2021 19:134

    Content type: Research

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  21. BLCA is a common cancer worldwide, and it is both aggressive and fatal. Immunotherapy (ICT) has achieved an excellent curative effect in BLCA; however, only some BLCA patients can benefit from ICT. MT1L is a p...

    Authors: Yanpeng Ding, Nuomin Liu, Mengge Chen, Yulian Xu, Sha Fang, Wenbin Xiang, Xinying Hua, Gaili Chen, Yahua Zhong and Haijun Yu

    Citation: World Journal of Surgical Oncology 2021 19:133

    Content type: Research

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  22. To compare the postoperative recurrence and fertility in patients with borderline ovarian tumors (BOTs) who underwent different surgical procedures: salpingo-oophorectomy versus cystectomy.

    Authors: Peng Wang and Lei Fang

    Citation: World Journal of Surgical Oncology 2021 19:132

    Content type: Research

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  23. Radiotherapy is a main therapeutic method for cancers, including colon cancer. In the current study, we aim to explore the effects of circular RNA (circRNA) circ_0055625 in the progression and radiosensitivity...

    Authors: Chao Gao, Yi Zhang, Yanming Tian, Chun Han, Lan Wang, Boyue Ding, Hua Tian, Chaoxi Zhou, Yingchao Ju, Ale Peng and Qiyao Yu

    Citation: World Journal of Surgical Oncology 2021 19:131

    Content type: Research

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  24. The application of side-to-end anastomosis (SEA) in sphincter-preserving resection (SPR) is controversial. We performed a meta-analysis to compare the safety and efficacy of SEA with colonic J-pouch (CJP) anas...

    Authors: Sen Hou, Quan Wang, Shidong Zhao, Fan Liu, Peng Guo and Yingjiang Ye

    Citation: World Journal of Surgical Oncology 2021 19:130

    Content type: Review

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  25. During the past two decades, laparoscopic radical nephroureterectomy (LRNU) has been proposed as an alternative technique to open radical nephroureterectomy (ORNU) and has become increasingly accepted for the ...

    Authors: Radosław Piszczek, Łukasz Nowak, Wojciech Krajewski, Joanna Chorbińska, Sławomir Poletajew, Marco Moschini, Krzysztof Kaliszewski and Romuald Zdrojowy

    Citation: World Journal of Surgical Oncology 2021 19:129

    Content type: Review

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  26. Although the ACOSOG Z0011 study showed that axillary lymph node dissection (ALND) could be avoided in a specific population of sentinel lymph node-positive patients, it is not widely accepted by Chinese surgeo...

    Authors: Yuan Peng, Miao Liu, Xianan Li, Fuzhong Tong, Yingming Cao, Peng Liu, Bo Zhou, Hongjun Liu, Lin Cheng, Jiajia Guo, Fei Xie, Houpu Yang, Siyuan Wang, Chaobin Wang, Yalin Chen and Shu Wang

    Citation: World Journal of Surgical Oncology 2021 19:128

    Content type: Research

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  27. Most previous studies compared survival between left-sided and right-sided colon cancer without adjustment for clinicopathological parameters. We investigated the effect of sidedness on survival among patients...

    Authors: Zhuang-Sheng Huang, Jun-Wei Wu, Ying Li, Yu-Hai Lin and Xu-Yuan Li

    Citation: World Journal of Surgical Oncology 2021 19:127

    Content type: Research

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  28. Pancreatic ductal adenocarcinoma (PDAC) is an aggressive malignancy with poor prognosis. Radical surgery is the best option for cure and, nowadays, it is performed by many surgeons also in cases of vascular in...

    Authors: Claudio F. Feo, Giulia Deiana, Chiara Ninniri, Giuseppe Cherchi, Paola Crivelli, Alessandro Fancellu, Giorgio C. Ginesu and Alberto Porcu

    Citation: World Journal of Surgical Oncology 2021 19:126

    Content type: Research

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  29. Lymphovascular invasion (LVI) is defined as the presence of cancer cells in lymphatics or blood vessels. This study aimed to evaluate the prognostic value of LVI in stage II colorectal cancer (CRC) patients wi...

    Authors: Zhenyan Gao, Huihua Cao, Xiang Xu, Qing Wang, Yugang Wu and Qicheng Lu

    Citation: World Journal of Surgical Oncology 2021 19:125

    Content type: Research

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  30. Adjuvant tegafur-gimeracil-oteracil (S-1) is commonly used for gastric cancer in Asia, and tegafur-uracil (UFT) is another oral fluoropyrimidine when S-1 is unavailable. The real-world data of adjuvant UFT has...

    Authors: Hung-Hsuan Yen, Chiung-Nien Chen, Chi-Chuan Yeh and I-Rue Lai

    Citation: World Journal of Surgical Oncology 2021 19:124

    Content type: Research

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  31. Pancreatic cancer (PAC) is one of the most devastating cancer types with an extremely poor prognosis, characterized by a hypoxic microenvironment and resistance to most therapeutic drugs. Hypoxia has been foun...

    Authors: Jianfeng Ding, Xiaobo He, Xiao Cheng, Guodong Cao, Bo Chen, Sihan Chen and Maoming Xiong

    Citation: World Journal of Surgical Oncology 2021 19:123

    Content type: Research

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  32. Long non-coding RNA (lncRNA) prostate androgen-regulated transcript 1 (PART1) was previously shown to exert an oncogenic role in several human cancers. However, whether PART1 is associated with the malignant p...

    Authors: Xibao Hu, Lei Zhang, Jingjing Tian and Junhong Ma

    Citation: World Journal of Surgical Oncology 2021 19:122

    Content type: Research

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  33. It has been reported that long-chain non-coding RNA (lncRNA) zinc finger E-box binding homeobox 1 antisense 1 (ZEB1-AS1) is an oncogene in various cancers, including hepatocellular carcinoma (HCC). We investig...

    Authors: Shuai Xue, Fengqin Lu, Chunhui Sun, Jingjing Zhao, Honghua Zhen and Xin Li

    Citation: World Journal of Surgical Oncology 2021 19:121

    Content type: Research

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  34. The Chinese Society of Clinical Oncology guidelines 2018 and the recent update of that (version 2020) recommends accurate examination before major treatment for decision(s) in cases of colon cancer. Also, the ...

    Authors: Yadong Zhou, Zhiwei Han, Fafu Dou and Tao Yan

    Citation: World Journal of Surgical Oncology 2021 19:120

    Content type: Research

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  35. Endoscopic resection (ER) might affect subsequent laparoscopic gastrectomy (LG) because of the electrical coagulation, but the effect remains controversial. The purpose of this meta-analysis was to analyze the...

    Authors: Dong Peng, Yu-Xi Cheng and Gang Liao

    Citation: World Journal of Surgical Oncology 2021 19:119

    Content type: Research

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  36. The optimal type of operative drainage following pancreaticoduodenectomy (PD) remains unclear. Our objective is to investigate risk associated with closed drainage techniques (passive [gravity] vs. suction) af...

    Authors: Bradley R. Hall, Zachary H. Egr, Robert W. Krell, James C. Padussis, Valerie K. Shostrom, Chandrakanth Are and Bradley N. Reames

    Citation: World Journal of Surgical Oncology 2021 19:118

    Content type: Research

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  37. Radical resection is associated with good prognosis among patients with cT1/T2Nx rectal cancer. However, still some of the patients experienced cancer recurrence following radical resection. This study tried t...

    Authors: I-Li Lai, Jeng-Fu You, Yih-Jong Chern, Wen-Sy Tsai, Jy-Ming Chiang, Pao-Shiu Hsieh, Hsin-Yuan Hung and Yu-Jen Hsu

    Citation: World Journal of Surgical Oncology 2021 19:116

    Content type: Research

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  38. The reliability of the registered ligation level of the inferior mesenteric artery (IMA) in the Swedish Colorectal Cancer Registry has been questioned. The primary aim of this study was to evaluate this parame...

    Authors: Franciska Wikner, Peter Matthiessen, Karl Sörelius, Petter Legrell and Martin Rutegård

    Citation: World Journal of Surgical Oncology 2021 19:115

    Content type: Research

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  39. Due to the high variability of incidence and prevalence of intra-mammary lymph nodes (IMLNs), they might be overlooked during clinical and radiological examinations. Properly characterizing pathological IMLNs ...

    Authors: Tarek Hashem, Ahmed Abdelmoez, Ahmed Mohamed Rozeka and Hazem Abdelazeem

    Citation: World Journal of Surgical Oncology 2021 19:114

    Content type: Research

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