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  1. The optimal axillary lymph node (ALN) management strategy in patients diagnosed with ductal carcinoma in situ (DCIS) preoperatively remains controversial. The value of breast magnetic resonance imaging (MRI) t...

    Authors: Hung-Wen Lai, Yi-Lin Chang, Shou-Tung Chen, Yu-Jun Chang, Wen-Pei Wu, Dar-Ren Chen, Shou-Jen Kuo, Chiung-Ying Liao and Hwa-Koon Wu

    Citation: World Journal of Surgical Oncology 2021 19:263

    Content type: Research

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  2. This study aimed to investigate the correlation between miRNA-216b expression in patients with non-small cell lung cancer (NSCLC) and 18F-fluorodeoxyglucose (FDG) uptake by PET/CT and to explore the clinical appl...

    Authors: Mingfei Zuo, Lan Yao, Lijuan Wen, Jianfei Shen, Na Zhang, Tian Bai and Qicheng Huang

    Citation: World Journal of Surgical Oncology 2021 19:262

    Content type: Research

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  3. The study aimed to compare the Steroid 5 alpha-reductase 3 (SRD5A3) expression levels in breast cancer (BC) and normal tissues, to investigate the prognostic value of SRD5A3 mRNA expression in BC patients and ...

    Authors: Yong-ping Zhang, Wen-ting Na, Xiao-qiang Dai, Ruo-fei Li, Jian-xiong Wang, Ting Gao, Wei-bo Zhang and Cheng Xiang

    Citation: World Journal of Surgical Oncology 2021 19:260

    Content type: Research

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  4. The aberrant expression of circular RNAs (circRNAs) plays vital roles in the advancement of human cancers, including gastric cancer (GC). In this study, the functions of circRNA ring finger protein 111 (circ-R...

    Authors: Guoxian Wu, Aimin Zhang, Yinglin Yang and Dongping Wu

    Citation: World Journal of Surgical Oncology 2021 19:259

    Content type: Research

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  5. The standard treatment of stage III N2 small cell lung cancer (SCLC) is concurrent chemoradiation, and surgery is not recommended. This study was aimed to evaluate whether surgery has survival benefits in pati...

    Authors: Yanfei Chai, Yuchao Ma, Wei Feng, Hongwei Lu and Longyu Jin

    Citation: World Journal of Surgical Oncology 2021 19:258

    Content type: Research

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  6. To establish a risk prediction model for pancreatic fistula according to the pancreatic fistula standards of the 2016 edition.

    Authors: Jun Yu, Chao-yi Ren, Jun Wang, Wei Cui, Jin-juan Zhang and Yi-jun Wang

    Citation: World Journal of Surgical Oncology 2021 19:257

    Content type: Research

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  7. To evaluate the clinicopathologic value of morphological growth patterns of small renal cell carcinoma (sRCC) and determine the actual demand for taking a rim of healthy parenchyma to avoid positive SM.

    Authors: Gang Li, Tengfei Xiao, Keruo Wang, Renya Zhang, Aixiang Wang, Chengzhi Yan and Chunhui Wang

    Citation: World Journal of Surgical Oncology 2021 19:255

    Content type: Research

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  8. Li-Fraumeni is a rare autosomal dominant cancer predisposition syndrome. The basis is a germline mutation of TP53 gene which encodes tumor suppressor protein resulting in early onset of tumors, most often breast ...

    Authors: Juraj Prejac, Natalija Dedić Plavetić, Kristina Gotovac Jerčić and Fran Borovečki

    Citation: World Journal of Surgical Oncology 2021 19:254

    Content type: Case report

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  9. The impact of primary tumour location on the prognosis of patients with peritoneal metastasis (PM) arising from colorectal cancer (CRC) after cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemot...

    Authors: Haipeng Chen, Sicheng Zhou, Jianjun Bi, Qiang Feng, Zheng Jiang, Jianping Xu, Wei Pei, Jianwei Liang, Zhixiang Zhou and Xishan Wang

    Citation: World Journal of Surgical Oncology 2021 19:253

    Content type: Research

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  10. The aim of this study was to identify predictors of mortality in elderly patients undergoing colorectal cancer surgery and to develop a risk score.

    Authors: Nerea González, Ane Loroño, Urko Aguirre, Santiago Lázaro, Marisa Baré, Maximino Redondo, Eduardo Briones, Cristina Sarasqueta, Amaia Bilbao, Nerea Fernández de Larrea and José María Quintana

    Citation: World Journal of Surgical Oncology 2021 19:252

    Content type: Research

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  11. There have been controversial voices on if hepatitis B virus infection decreases the risk of colorectal liver metastases or not. This study aims to the find the association between HBV infection and postoperat...

    Authors: Ziyao Li, Shaofei Li, Hangbo Tao, Yixiang Zhan, Kemin Ni, Jianfeng Gong and Guoxun Li

    Citation: World Journal of Surgical Oncology 2021 19:251

    Content type: Research

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  12. To retrospectively analyze the safety and long-term clinical efficacy of gelatin sponge microparticles combined with the chemotherapy drug pirarubicin for hepatic transcatheter arterial chemoembolization (GSMs...

    Authors: Guang Sheng Zhao, Song Liu, Ying Liu, Jian Ma, Ruo Yu Wang, Jie Bian, Jun Zhou, Jian Lin Wu and Yue Wei Zhang

    Citation: World Journal of Surgical Oncology 2021 19:249

    Content type: Research

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  13. Colorectal cancer (CRC) is one of the most common cancers of the gastrointestinal tract and ranks third in cancer-related deaths worldwide. This study was conducted to identify novel biomarkers related to the ...

    Authors: Xuan Yang, Wangao Wei, Shisheng Tan, Linrui Guo, Song Qiao, Biao Yao and Zi Wang

    Citation: World Journal of Surgical Oncology 2021 19:248

    Content type: Research

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  14. Previous studies had shown that microRNA-638 (miR-638) exhibited different effects in malignant tumors. Moreover, the function of miR-638 has not been reported in breast cancer. Hence, we designed this researc...

    Authors: Qian Xu, Qianqian Zhang, Mengli Dong and Yuan Yu

    Citation: World Journal of Surgical Oncology 2021 19:247

    Content type: Research

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  15. Circular RNAs (circRNAs) are increasingly implicated in regulating human carcinogenesis. Previous work showed the oncogenic activity of circ_0018289 in cervical cancer. However, the molecular basis underlying ...

    Authors: Heng Zou, Huijia Chen, Shuaibin Liu and Xiaoling Gan

    Citation: World Journal of Surgical Oncology 2021 19:246

    Content type: Research

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  16. The optimal treatment in patients with gastric cancer and peritoneal disease remains controversial. Some guidelines indicate palliative treatment only, while others consider surgical treatment in case of posit...

    Authors: Massimiliano Valletti, Dilmurodjon Eshmuminov, Nicola Gnecco, Christian Alexander Gutschow, Paul Magnus Schneider and Kuno Lehmann

    Citation: World Journal of Surgical Oncology 2021 19:245

    Content type: Research

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  17. Adequate margins are technically difficult to achieve for malignant tumors involving the sacroiliac joint due to limited accessibility and viewing window. In order to address the technical difficulties faced i...

    Authors: Tao Ji, Brian Z. J. Chin, Xiaodong Tang, Rongli Yang and Wei Guo

    Citation: World Journal of Surgical Oncology 2021 19:243

    Content type: Research

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  18. To investigate the expression and clinical significance of EFNA1 in broad-spectrum tumors, and to evaluate its relationship with prognosis and biological functions of esophageal carcinoma (ESCA).

    Authors: Yongqiang Zhang, Jinning Zhang, Guanlong Pan, Tianhao Guan, Changhao Zhang, An Hao, Yan Li and Hai Ren

    Citation: World Journal of Surgical Oncology 2021 19:242

    Content type: Research

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  19. Hepatocellular carcinoma (HCC) is one of the most common malignancies in the world, and due to its complex pathogenic factors, its prognosis is poor. N6-methyladenosine (m6A) RNA methylation plays an important ro...

    Authors: Jihao Cai, Minglei Zhou and Jianxin Xu

    Citation: World Journal of Surgical Oncology 2021 19:241

    Content type: Research

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  20. Oral cancer (OC) is a common and dangerous malignant tumor with a low survival rate. However, the micro level mechanism has not been explained in detail.

    Authors: Abdusemer Reyimu, Ying Chen, Xudong Song, Wubi Zhou, Jingjing Dai and Feng Jiang

    Citation: World Journal of Surgical Oncology 2021 19:240

    Content type: Research

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  21. miR-92b is a carcinogenic miRNA that has great potential as a biomarker for disease prognosis, diagnosis, and treatment in the clinic. It is of great significance to analyse the relationship between miR-92b an...

    Authors: Yu Du, Zhuang Miao, Kedi Wang, Yan Lv, Lijuan Qiu and Lusheng Guo

    Citation: World Journal of Surgical Oncology 2021 19:239

    Content type: Research

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  22. Only 50–70% of elderly colon cancer patients could complete the recommended 6 months of postoperative chemotherapy. It is unknown whether a shorter duration of postoperative capecitabine-alone chemotherapy wou...

    Authors: Weiwei Chen, Hongmin Dong, Gang Wang, Juan Chen and Wenling Wang

    Citation: World Journal of Surgical Oncology 2021 19:238

    Content type: Research

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  23. This article is a commentary on an article published in World Journal of Surgical Oncology by Liu et al. With this study, authors evaluated diagnostic accuracy of Xpert bladder cancer monitor in detecting recurre...

    Authors: Gopal Sharma

    Citation: World Journal of Surgical Oncology 2021 19:237

    Content type: Correspondence

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    The original article was published in World Journal of Surgical Oncology 2021 19:42

  24. Peritoneal malignancies include primary and metastatic cancer of the peritoneal cavity. The most common origin for peritoneal metastasis is ovarian, gastric, and colorectal cancers. Irrespective of the origin,...

    Authors: Rokas Račkauskas, Augustinas Baušys, Martynas Lukšta, Jonas Jurgaitis, Marius Paškonis and Kęstutis Strupas

    Citation: World Journal of Surgical Oncology 2021 19:236

    Content type: Research

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  25. Long-lasting reconstruction after extensive resection involving peri-knee metaphysis is a challenging problem in orthopedic oncology. Various reconstruction methods have been proposed, but they are characteriz...

    Authors: Jie Wang, Jingjing An, Minxun Lu, Yuqi Zhang, Jingqi Lin, Yi Luo, Yong Zhou, Li Min and Chongqi Tu

    Citation: World Journal of Surgical Oncology 2021 19:235

    Content type: Research

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  26. To avoid the inconvenience of triangulation among various rigid operating instruments in mediastinoscopy-assisted esophagectomy, we invented a new technique: used a flexible endoscope to mobilize thoracic esop...

    Authors: Chun-Li Wu, Bo Dong, Bin Wu, Shi-Hao Li and Yu Qi

    Citation: World Journal of Surgical Oncology 2021 19:234

    Content type: Technical innovations

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  27. Colon neuroendocrine neoplasms (NENs) have one of the poorest median overall survival (OS) rates among all NENs. The American Joint Committee on Cancer (AJCC) tumor–node–metastasis (TNM) staging system—current...

    Authors: Ruitong Xu, Bingrong Zhou, Ping Hu, Bingyan Xue, Danyang Gu, Xiaolin Li and Qiyun Tang

    Citation: World Journal of Surgical Oncology 2021 19:233

    Content type: Research

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  28. The clinical efficacy and safety of maintenance therapy (MT) for patients with advanced non-small cell lung cancer (NSCLC) have not been determined in the real word. This retrospective study of real-world data...

    Authors: Xiangwei Xu, Ruya Li, Peizhen Zhu, Penghai Zhang, Jun Chen, Yongsheng Lin and Yinqiao Chen

    Citation: World Journal of Surgical Oncology 2021 19:231

    Content type: Research

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  29. Digestive tract reconstruction in totally laparoscopic total gastrectomy can be divided into two types: instrument anastomosis and hand-sewn anastomosis. This study explored the feasibility and safety of hand-...

    Authors: Zeshen Wang, Yuzhe Wei, Xirui Liu, Zhenglong Li, Guanyu Zhu, Yanfeng Li and Kuan Wang

    Citation: World Journal of Surgical Oncology 2021 19:229

    Content type: Research

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  30. The purposes of this study were to assess the correlation between the plasma level of Hsp90α and the clinicopathological characteristics of patients with liver cancer and compare the diagnostic efficacy of Hsp...

    Authors: Yueting Han, Youqin Zhang, Lin Cui, Ze Li, Honglei Feng, Ying Zhang, Da Sun and Li Ren

    Citation: World Journal of Surgical Oncology 2021 19:228

    Content type: Research

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  31. Immunoinflammatory and nutritional markers, such as the peripheral blood neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR) and Onodera’s prognostic nutritional index (OPNI), have gained ...

    Authors: Feng Wang, Tingting Tao, Heng Yu, Yingying Xu, Zhi Yang, Xuefeng Xia, Meng Wang, Liang Zong and Wenxian Guan

    Citation: World Journal of Surgical Oncology 2021 19:227

    Content type: Research

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  32. Intrahepatic cholangiocarcinoma is an aggressive liver carcinoma with increasing incidence and mortality. A good auxiliary prognostic prediction tool is desperately needed for the development of treatment stra...

    Authors: Youyin Tang, Tao Zhang, Xianghong Zhou, Yunuo Zhao, Hanyue Xu, Yichun Liu, Hang Wang, Zheyu Chen and Xuelei Ma

    Citation: World Journal of Surgical Oncology 2021 19:45

    Content type: Research

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  33. Extramedullary leukemia, also known as myeloid sarcoma, is a rare form of acute myeloid leukemia and often accompanies bone marrow involvement. Myeloid infiltration of the thyroid gland is extremely rare. Here...

    Authors: Mehmet Sözen, Çiğdem Vural, Alev Selek, Umay Kiraz, Zeynep Cantürk, Berrin Çetinarslan, Emre Gezer and Damla Köksalan

    Citation: World Journal of Surgical Oncology 2021 19:225

    Content type: Case report

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  34. 5-Methylcytosine (m5C) is a reversible modification to both DNA and various cellular RNAs. However, its roles in developing human cancers are poorly understood, including the effects of mutant m5C regulators and ...

    Authors: Yuting He, Xiao Yu, Menggang Zhang and Wenzhi Guo

    Citation: World Journal of Surgical Oncology 2021 19:224

    Content type: Research

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  35. While large-scale genomic analyses symbolize a precious attempt to decipher the molecular foundation of uterine leiomyosarcoma (ULMS), bioinformatics results associated with the occurrence of ULMS based totall...

    Authors: Xiaoqing Shen, Zhujuan Yang, Songwei Feng and Yi Li

    Citation: World Journal of Surgical Oncology 2021 19:223

    Content type: Research

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  36. Surgical resection (SR) has been selectively applied in hepatocellular carcinoma (HCC) presenting with minor gross vascular invasion (mGVI) which is defined when tumor invasion is confined to second-order port...

    Authors: Byungje Bae, Sung Kyu Song, Eunyoung Choi, Chul-Woon Chung and Yongkeun Park

    Citation: World Journal of Surgical Oncology 2021 19:222

    Content type: Research

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  37. The aim of this study is to determine the incidence trends of urothelial cancer of the bladder (UCB) and to develop a nomogram for predicting the cancer-specific survival (CSS) of postsurgery UCB at a populati...

    Authors: Hairong He, Tianjie Liu, Didi Han, Chengzhuo Li, Fengshuo Xu, Jun Lyu and Ye Gao

    Citation: World Journal of Surgical Oncology 2021 19:221

    Content type: Research

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  38. The aim of this study was to analyze prognostic factors for ovarian metastases (OM) in colorectal cancer (CRC) using data from a Chinese center. In addition, the study aimed at developing a new clinical scorin...

    Authors: Chao Chen, Da Wang, Xiaoxu Ge, Jian Wang, Yuhuai Huang, Tianyi Ling, Tian Jin, Jinhua Yang, Fengping Wang, Weihong Wu and Lifeng Sun

    Citation: World Journal of Surgical Oncology 2021 19:220

    Content type: Research

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  39. Gastric cancer (GC) commonly relates to dismal prognosis and lacks efficient biomarkers. This study aimed to establish an antioxidant-related gene signature and a comprehensive nomogram to explore novel biomar...

    Authors: Jianhua Wu, Xuan Wang, Nan Wang, Li Ma, Xin Xie, Hao Zhang, Huafeng Kang and Zhangjian Zhou

    Citation: World Journal of Surgical Oncology 2021 19:219

    Content type: Research

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  40. Systemic inflammation and nutritional status are associated with tumor development and progression. This study investigated the prognostic value of fibrinogen/albumin ratio index (FARI) in predicting recurrenc...

    Authors: Hu Liu, Guoteng Qiu, Fengjuan Hu and Hong Wu

    Citation: World Journal of Surgical Oncology 2021 19:218

    Content type: Research

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  41. Despite the established oncological benefits of neoadjuvant chemotherapy for esophageal squamous cell cancer, not all cases demonstrate benefit. Hence, predicting the response to chemotherapy before treatment ...

    Authors: Seiichi Nakaya, Ryo Ogawa, Shunsuke Hayakawa, Shiro Fujihata, Tomotaka Okubo, Hiroyuki Sagawa, Tatsuya Tanaka, Hiroki Takahashi, Yoichi Matsuo and Shuji Takiguchi

    Citation: World Journal of Surgical Oncology 2021 19:217

    Content type: Research

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  42. Gastric cancer (GC) represents a major malignancy and is the third deathliest cancer globally. Several lines of evidence indicate that the epithelial-mesenchymal transition (EMT) has a critical function in the...

    Authors: Wanting Song, Yi Bai, Jialin Zhu, Fanxin Zeng, Chunmeng Yang, Beibei Hu, Mingjun Sun, Chenyan Li, Shiqiao Peng, Moye Chen and Xuren Sun

    Citation: World Journal of Surgical Oncology 2021 19:216

    Content type: Research

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  43. The programmed death 1 (PD-1)/programmed death-ligand 1 (PD-L1) have shown positive efficacy in several solid cancers due to their targeted antitumour effects. However, the frequency and clinical implication v...

    Authors: Juan He, Min Yi, Lingfeng Tan, Jianghua Huang and Lin Huang

    Citation: World Journal of Surgical Oncology 2021 19:215

    Content type: Research

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  44. The radiation-induced lung injury (RILI) in patients with advanced non-small cell lung cancer (NSCLS) is very common in clinical settings; we aimed to evaluate the risk factors of RILI in NSCLS patients, to pr...

    Authors: Sha Sha, Jigang Dong, Maoyu Wang, Ziyu Chen and Peng Gao

    Citation: World Journal of Surgical Oncology 2021 19:214

    Content type: Research

    Published on:

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