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  1. To assess the feasibility and short-term outcomes of neoadjuvant chemoradiotherapy (CCRT) followed by transanal total mesorectal excision assisted by single-port laparoscopic surgery (TaTME-SPLS) for low-lying...

    Authors: Yen-Jung Lu, Chien-Hsin Chen, En-Kwang Lin and Szu-Yuan Wu

    Citation: World Journal of Surgical Oncology 2020 18:198

    Content type: Research

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  2. Systemic immune-inflammation index (SII) has been suggested to be effective to reflect the inflammatory status and thus may be an underlying biomarker for prognosis prediction. This hypothesis has been demonst...

    Authors: Yongfang Ji and Haiyan Wang

    Citation: World Journal of Surgical Oncology 2020 18:197

    Content type: Review

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  3. Patients with stage II deficient mismatch repair (dMMR) show a better prognosis than patients with colorectal cancer (CRC) with proficient mismatch repair (pMMR). However, this beneficial effect is decreased i...

    Authors: Bingyan Wang, Fei Li, Limei Guo, Siyi Lu, Junren Ma, Yanpeng Ma, Yan Meng, Junwei Wang, Xin Zhou and Wei Fu

    Citation: World Journal of Surgical Oncology 2020 18:196

    Content type: Research

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  4. Although hereditary non-polyposis colorectal cancer (HNPCC) could be subtyped into proficient or deficient mismatch repair gene expression (pMMR or dMMR), distinct clinical features between these two subgroups...

    Authors: Ci-Yuan Sun, Jy-Ming Chiang, Tse-Ching Chen, Hsin-Yun Hung and Jeng-Fu You

    Citation: World Journal of Surgical Oncology 2020 18:195

    Content type: Research

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  5. Frailty results in a high risk for disability, hospitalization, and mortality. This study aimed to investigate perioperative details of frail patients who underwent pancreatectomy and whether frailty can be a ...

    Authors: Yutaka Nakano, Yuki Hirata, Tatsuya Shimogawara, Toru Yamada, Koki Mihara, Ryo Nishiyama, Shin Nishiya, Hideki Taniguchi and Tomohisa Egawa

    Citation: World Journal of Surgical Oncology 2020 18:194

    Content type: Research

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  6. The impact of primary tumor resection (PTR) on the prognosis of unresectable metastatic colorectal cancer (mCRC) patients remains debatable. We aimed to develop several prognostic nomograms which could be usef...

    Authors: Yi Yang, Yujie Lu, Wen Jiang, Jinzhou Zhu and Su Yan

    Citation: World Journal of Surgical Oncology 2020 18:193

    Content type: Research

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  7. Several studies have reported the Cyclooxygenase 2 (COX-2) rs689466 polymorphism as a susceptibility locus of colorectal cancer (CRC), but their findings are inconsistent. Thus, this meta-analysis was performe...

    Authors: Yong-Chen Zhang, Hui Zhao, Chen Chen and Mohammad Amzad Ali

    Citation: World Journal of Surgical Oncology 2020 18:192

    Content type: Research

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  8. Pre-treatment PLR (platelet-lymphocyte ratio) was reported to be associated with the prognosis in gastric cancer (GC), but the results remain inconclusive. This meta-analysis aimed to investigate the prognosti...

    Authors: Xunlei Zhang, Wenjing Zhao, Yang Yu, Xue Qi, Li Song, Chenfei Zhang, Guoxing Li and Lei Yang

    Citation: World Journal of Surgical Oncology 2020 18:191

    Content type: Research

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  9. Colorectal cancer resection surgery with transvaginal specimen extraction is becoming increasingly accepted and used by surgeons. However, few publications on robotic anterior sigmoid colon and rectal cancer r...

    Authors: Gengmei Gao, Lan Chen, Rui Luo, Bo Tang and Taiyuan Li

    Citation: World Journal of Surgical Oncology 2020 18:190

    Content type: Research

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  10. Hepatocellular carcinoma (HCC) is a malignant tumor with frequent intrahepatic metastases; extrahepatic metastases are not rare but less frequent compared to intrahepatic ones. The most frequent sites of extra...

    Authors: Yong-Ming Yu, Yi-Sheng Cao, Zhou Wu, Rong Huang and Zhong-Lei Shen

    Citation: World Journal of Surgical Oncology 2020 18:189

    Content type: Case report

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  11. Lateral lymph node metastasis (LLNM) is very common in papillary thyroid carcinoma (PTC). The influence of tumour location on LLNM remains controversial. The purpose of this study was to reveal the association...

    Authors: Yi Dou, Daixing Hu, Yingji Chen, Wei Xiong, Qi Xiao and Xinliang Su

    Citation: World Journal of Surgical Oncology 2020 18:188

    Content type: Research

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  12. Neoplastic spinal cord compression is a cause of severe disability in cancer patients. To prevent irreversible paraplegia, a structured strategy is required to address the various impairments present in cancer...

    Authors: Yukako Ishida, Hideki Shigematsu, Shinji Tsukamoto, Yasuhiko Morimoto, Eiichiro Iwata, Akinori Okuda, Sachiko Kawasaki, Masato Tanaka, Hiromasa Fujii, Yasuhito Tanaka and Akira Kido

    Citation: World Journal of Surgical Oncology 2020 18:187

    Content type: Research

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  13. Recently, reports have classified lymphocyte to monocyte ratio (LMR) as an effective indicator for predicting the prognosis of pancreatic cancer. Nevertheless, the prognostic value of LMR for pancreatic cancer...

    Authors: Shuwen Lin, Yinghua Fang, Zhikang Mo, Ye Lin, Chenggang Ji and Zhixiang Jian

    Citation: World Journal of Surgical Oncology 2020 18:186

    Content type: Research

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  14. Tumor size is one of the most important issues for hepatocellular carcinoma (HCC) treatment and prognosis, but the classification of it is still controversial. The aim of this study was to screen appropriate c...

    Authors: Hongzhi Liu, Yuan Yang, Chuanchun Chen, Lei Wang, Qizhen Huang, Jianxing Zeng, Kongying Lin, Yongyi Zeng, Pengfei Guo, Weiping Zhou and Jingfeng Liu

    Citation: World Journal of Surgical Oncology 2020 18:185

    Content type: Research

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  15. Talc pleurodesis (TP) and indwelling pleural catheter (IPC) are used for the management of malignant pleural effusion (MPE). Our meta-analysis was conducted to assess the efficacy and safety of both treatments...

    Authors: Li Wang, Huan Deng, Xinling Chen, Can Li, Fengming Yi, Yiping Wei and Wenxiong Zhang

    Citation: World Journal of Surgical Oncology 2020 18:184

    Content type: Research

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  16. Gastrointestinal stromal tumors (GIST) arising from sites other than the gastrointestinal (GI) tract, termed extra-gastrointestinal stromal tumors (EGIST), are rare. Among EGIST, those with platelet-derived gr...

    Authors: Kohei Kanamori, Yukinori Yamagata, Yoshitaka Honma, Keiichi Date, Takeyuki Wada, Tsutomu Hayashi, Sho Otsuki, Shigeki Sekine, Takaki Yoshikawa, Hitoshi Katai and Toshiro Nishida

    Citation: World Journal of Surgical Oncology 2020 18:183

    Content type: Case report

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  17. Appendiceal and colorectal cancers with peritoneal carcinomatosis (PC) can derive benefit from cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS/HIPEC). However, its role in gastric and ...

    Authors: Natasha Leigh, Daniel Solomon, Eric Pletcher, Daniel M. Labow, Deepa R. Magge, Umut Sarpel and Benjamin J. Golas

    Citation: World Journal of Surgical Oncology 2020 18:182

    Content type: Research

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  18. The purpose of this study is to explore the role and mechanism of MMP-9 in the EMT process of thyroid cancer (TC), so as to provide a basis for clinical exploration of invasion and metastasis process of TC, lo...

    Authors: Yuanchun Li, Jing He, Feng Wang, Xin Wang, Fan Yang, Chunyang Zhao, Chunling Feng and Tiejun Li

    Citation: World Journal of Surgical Oncology 2020 18:181

    Content type: Research

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  19. The purpose of this study is to compare the difference of clinical efficacy between conventional intraperitoneal chemotherapy and HIPEC, so as to explore the clinical application value and advantages of HIPEC.

    Authors: Jie Jiao, Chengzhen Li, Guanying Yu, Lei Zhang, Xiaoyan Shi, Jingdu Yan, Houjun Zhang and Peiming Guo

    Citation: World Journal of Surgical Oncology 2020 18:180

    Content type: Research

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  20. Patients with stage IV gastric cancer have a poor prognosis despite the recent development of multidisciplinary treatments that include chemotherapy. However, conversion surgery has emerged as a promising stra...

    Authors: Ryu Matsumoto, Takaaki Arigami, Daisuke Matsushita, Keishi Okubo, Takako Tanaka, Shigehiro Yanagita, Ken Sasaki, Masahiro Noda, Yoshiaki Kita, Shinichiro Mori, Hiroshi Kurahara and Takao Ohtsuka

    Citation: World Journal of Surgical Oncology 2020 18:179

    Content type: Case report

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  21. Sentinel lymph node biopsy (SLNB) plays a vital role in breast cancer surgery, and the identified number of sentinel nodes determines its accuracy for representing the status of the axillae. There are two type...

    Authors: Chenxi Yuan, Xinzhao Wang, Zhaoyun Liu, Chao Li, Mengxue Bian, Jing Shan, Xiang Song, Zhiyong Yu and Jinming Yu

    Citation: World Journal of Surgical Oncology 2020 18:178

    Content type: Research

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  22. We aimed to investigate the usefulness of magnetic resonance imaging (MRI) and histopathological shrinkage patterns to formulate a predictive equation for estimating residual tumor size after neoadjuvant chemo...

    Authors: Katsuhiro Yoshikawa, Mitsuaki Ishida, Naoki Kan, Hirotsugu Yanai, Koji Tsuta, Mitsugu Sekimoto and Tomoharu Sugie

    Citation: World Journal of Surgical Oncology 2020 18:177

    Content type: Research

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  23. Deoxycytidine kinase (DCK), an enzyme in the nucleoside biosynthetic pathway, can affect the development of immune cells. However, the relationships between the expression of DCK, patient prognosis, and tumor-inf...

    Authors: Danjun Song, Yining Wang, Kai Zhu, Lingyu Tian, Qiang Gao, Jian Zhou, Jia Fan and Xiaoying Wang

    Citation: World Journal of Surgical Oncology 2020 18:176

    Content type: Research

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  24. Previous randomized controlled trials have compared the efficacy and safety of single chest drain (SCD) and double chest drains (DCD) in the patients undergone pulmonary lobectomy, yet the results remain incon...

    Authors: Jinzhi You, Hailing Zhang, Wei Li, Ninghuang Dai and Zhongfeng Zheng

    Citation: World Journal of Surgical Oncology 2020 18:175

    Content type: Research

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  25. The effect and safety of preoperative biliary drainage (PBD) in patients with perihilar cholangiocarcinoma are still controversial; the aim of our study is to evaluate all aspects of PBD.

    Authors: Fei Teng, You-yin Tang, Jun-long Dai, Yongkun Li and Zhe-yu Chen

    Citation: World Journal of Surgical Oncology 2020 18:174

    Content type: Research

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  26. Limited data describe the therapeutic practice and outcomes of colorectal liver metastases (CRLMs) in elderly patients. We aimed to evaluate the impact of age on multidisciplinary treatment for CRLMs.

    Authors: Taigo Hata, Yoshihiro Mise, Yoshihiro Ono, Takafumi Sato, Yosuke Inoue, Hiromichi Ito, Yu Takahashi, Katsuhiko Yanaga and Akio Saiura

    Citation: World Journal of Surgical Oncology 2020 18:173

    Content type: Research

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  27. Several genetic driver alterations have been identified in micropapillary lung adenocarcinoma (MPA). However, the frequency of co-alteration of ROS1, EGFR, and EML4-ALK is yet unclear. Herein, we investigated the...

    Authors: Xilin Zhang, Yan Jiang, Huanming Yu, Hui Xia and Xiang Wang

    Citation: World Journal of Surgical Oncology 2020 18:172

    Content type: Research

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  28. Additional studies comparing several reconstruction methods after proximal gastrectomy have been published; of note, it is necessary to update systematic reviews and meta-analysis from the current evidence-bas...

    Authors: Zakari Shaibu, Zhihong Chen, Said Abdulrahman Salim Mzee, Acquah Theophilus and Isah Adamu Danbala

    Citation: World Journal of Surgical Oncology 2020 18:171

    Content type: Review

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  29. Pylorus-preserving gastrectomy (PPG) has been accepted as a function-preserving surgery for the treatment of early gastric cancer in East Asian countries. Therefore, this study aimed to evaluate the feasibilit...

    Authors: Yuji Akiyama, Akira Sasaki, Takeshi Iwaya, Ryosuke Fujisawa, Noriyuki Sasaki, Haruka Nikai, Fumitaka Endo, Shigeaki Baba, Yasushi Hasegawa, Toshimoto Kimura, Takeshi Takahara, Hiroyuki Nitta, Koki Otsuka and Keisuke Koeda

    Citation: World Journal of Surgical Oncology 2020 18:170

    Content type: Research

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  30. Skip metastases are defined as lateral lymph node metastasis (LNM) without the involvement of central LNM in papillary thyroid cancer (PTC), and it is difficult to predict in clinical practice. Our study aimed...

    Authors: Wenlong Wang, Zhi Yang and Qianhui Ouyang

    Citation: World Journal of Surgical Oncology 2020 18:167

    Content type: Research

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  31. The liver is a major target organ for metastases of various types of cancers. Surgery is a well-established option for colorectal liver metastases (CRLM). Regarding the improved surgical and anesthetic techniq...

    Authors: Rokas Račkauskas, Augustinas Baušys, Vitalijus Sokolovas, Marius Paškonis and Kęstutis Strupas

    Citation: World Journal of Surgical Oncology 2020 18:164

    Content type: Research

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  32. Surgical resection of metastatic disease in patients with initially non-resectable colorectal cancer (CRC) has improved overall survival. Intensified chemotherapy regimens have increased the probability of con...

    Authors: Mahmoud A. Elshenawy, Ahmed Badran, Ali Aljubran, Ahmed Alzahrani, M. Shahzad Rauf, Abdelmoneim Eldali and Shouki Bazarbashi

    Citation: World Journal of Surgical Oncology 2020 18:163

    Content type: Research

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  33. To identify the predictive factors associated with pleural drainage volume (PDV) after uniportal video-assisted thoracic surgery (VATS) lobectomy for non-small cell lung cancer (NSCLC).

    Authors: Ming-bo Tang, Jia-lin Li, Su-yan Tian, Xin-liang Gao and Wei Liu

    Citation: World Journal of Surgical Oncology 2020 18:162

    Content type: Research

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  34. Endometrial carcinoma (EC) is the most common gynecological malignant tumors which poses a serious threat to women health. This study aimed to screen the candidate genes differentially expressed in EC by bioin...

    Authors: Yiming Zhu, Liang Shi, Ping Chen, Yingli Zhang and Tao Zhu

    Citation: World Journal of Surgical Oncology 2020 18:161

    Content type: Research

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  35. Due to better functional outcomes, pylorus-preserving gastrectomy (PPG) has been widely applied for early gastric cancer (EGC) patients as an alternative to distal gastrectomy (DG). However, controversies stil...

    Authors: Xinyu Mao, Xinlei Xu, Hua Zhu, Chunpeng Ji, Xu Lu and Baolin Wang

    Citation: World Journal of Surgical Oncology 2020 18:160

    Content type: Research

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  36. To evaluate the feasibility and safety of a new surgical method, complete laparoscopic extended right hemicolectomy with preservation of the ileocecal junction in right-transverse colon cancer.

    Authors: Hao Su, Hongliang Wu, Bing Mu, Mandula Bao, Shou Luo, Chuanduo Zhao, Qian Liu, Xishan Wang, Zhixiang Zhou and Haitao Zhou

    Citation: World Journal of Surgical Oncology 2020 18:159

    Content type: Research

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  37. The Milan criteria (MC) are widely used for the indication of liver transplantation (LTx) in hepatocellular carcinoma (HCC). Good long-term results have also been reported following LTx for patients exceeding ...

    Authors: Mehmet Haluk Morgul, Philipp Felgendreff, Andreas Kienlein, Ulrich Gauger, Katrin Semmling, Hans-Michael Hau, Hans-Michael Tautenhahn and Michael Bartels

    Citation: World Journal of Surgical Oncology 2020 18:158

    Content type: Research

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  38. This study aimed to investigate the correlation of chaperonin containing t-complex polypeptide 1 subunit 6A (CCT6A) expression with clinicopathological features and survival profiles in non-small cell lung car...

    Authors: Ting Zhang, Wang Shi, Ke Tian and Yushan Kong

    Citation: World Journal of Surgical Oncology 2020 18:156

    Content type: Research

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  39. Rapid lethal exacerbation and recurrence featuring acute leukemoid reaction (ALR) after retrolaparoscopic radical nephrectomy (RN) is a relatively rare clinical incident. Performing the reoperation for the pat...

    Authors: Xuhui Zhang, Lijuan Yan, Xiaobin Yuan, Tao Bai, Lei Zhang and Shuaihong Han

    Citation: World Journal of Surgical Oncology 2020 18:155

    Content type: Case report

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  40. Renal hemangioblastoma (RH) is a very rare benign tumour. Hemangioblastoma most commonly occurs in the central nervous system (CNS), and only few cases of RH have been reported as they occur most commonly as a...

    Authors: Aparna Setia, Devender Kumar, Lovenish Bains, Pallavi Sharma, Anjali Tempe and Varuna Mallya

    Citation: World Journal of Surgical Oncology 2020 18:154

    Content type: Case report

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  41. Gallbladder cancer (GBC) is the most common and aggressive extra hepatic biliary tree cancer (BTC) with dismal outcome. Complete surgical resection is the treatment of choice. Chemotherapy is used for palliati...

    Authors: Kishan Soni, Tarun Kumar and Manoj Pandey

    Citation: World Journal of Surgical Oncology 2020 18:153

    Content type: Review

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  42. Anal cancer is a rare cancer with chemoradiation being the mainstay of treatment for locoregional presentation. In North America, the most common subtype is anal squamous cell carcinoma (epidermoid). A surgica...

    Authors: Vera Pravong, Alexandre Brind’Amour, Lucas Sidéris, Pierre Dubé and Jean-François Tremblay

    Citation: World Journal of Surgical Oncology 2020 18:152

    Content type: Case report

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  43. The purpose of this study was to explore the efficacy and tolerability of poly ADP-ribose polymerase (PARP) inhibitors in patients with ovarian cancer.

    Authors: Yingzhu Yang, Nannan Du, Laidi Xie, Jing Jiang, Jiahang Mo, Jiaze Hong, Danyi Mao, Derry Minyao Ng and Huiwei Shi

    Citation: World Journal of Surgical Oncology 2020 18:151

    Content type: Review

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  44. Currently, nivolumab and ipilimumab are the most widely used immune checkpoint inhibitors. We performed a meta-analysis to evaluate the efficacy and treatment-related adverse events (TRAEs) of nivolumab plus i...

    Authors: Jingjie Chen, Shengnan Li, Qigu Yao, Nannan Du, Xiaojun Fu, Yuanmei Lou, Mengru Wang, Feiyan Mao, Danyi Mao, Parikshit Asutosh Khadaroo and Yingying Tang

    Citation: World Journal of Surgical Oncology 2020 18:150

    Content type: Review

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  45. The purpose of this study was to compare clinicopathological features of patients with non-schistosomal and schistosomal colorectal cancer to explore the effect of schistosomiasis on colorectal cancer (CRC) pa...

    Authors: Weixia Wang, Kui Lu, Limei Wang, Hongyan Jing, Weiyu Pan, Sinian Huang, Yanchao Xu, Dacheng Bu, Meihong Cheng, Jing Liu, Jican Liu, Weidong Shen, Yingyi Zhang, Junxia Yao and Ting Zhu

    Citation: World Journal of Surgical Oncology 2020 18:149

    Content type: Research

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