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  1. Content type: Research

    According to the Response Evaluation Criteria in Solid Tumors (RECIST), progressive disease (PD) is diagnosed under two conditions: an increase in size of pre-existing lesions (IS) and the appearance of new le...

    Authors: Ryutaro Mori, Manabu Futamura, Kasumi Morimitsu, Yoshimi Asano, Yoshihisa Tokumaru, Mai Kitazawa and Kazuhiro Yoshida

    Citation: World Journal of Surgical Oncology 2018 16:169

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  2. Content type: Review

    Obesity is a risk factor for pancreatic cancer which may be treated with Roux-en-Y gastric bypass and represents an increasing morbidity. Post-RYGB anatomy poses considerable challenges for reconstruction afte...

    Authors: William F. Morano, Mohammad F. Shaikh, Elizabeth M. Gleeson, Alvaro Galvez, Marian Khalili, John Lieb II, Elizabeth P. Renza-Stingone and Wilbur B. Bowne

    Citation: World Journal of Surgical Oncology 2018 16:168

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  3. Content type: Research

    Safflower polysaccharide (SPS) is one of the most important active components of safflower (Carthamus tinctorius L.), which has been confirmed to have the immune-regulatory function and antitumor effect. This stu...

    Authors: Haiyan Zhou, Jing Yang, Chuhan Zhang, Yuwei Zhang, Rui Wang, Xiao Li and Shuainan Zhang

    Citation: World Journal of Surgical Oncology 2018 16:167

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  4. Content type: Case report

    Synovial sarcoma is a rare soft tissue sarcoma which most commonly affects the extremities of young adults. Axilla involvement by this sarcoma is very rare especially with involvement of the brachial plexus. T...

    Authors: Ziyad M. Mohaidat, Abed-Allah A. Saleh, Salah Al-gharaibeh and Ibrahim R. Yousef

    Citation: World Journal of Surgical Oncology 2018 16:166

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  5. Content type: Case report

    Rectal gastrointestinal stromal tumor (GIST) is a very rare tumor of gastrointestinal tract. Surgical management of rectal GIST requires special attention for preserving of anal and urinary functions. Transana...

    Authors: Pramod Nepal, Shinichiro Mori, Yoshiaki Kita, Kan Tanabe, Kenji Baba, Yasuto Uchikado, Hiroshi Kurahara, Takaaki Arigami, Masahiko Sakoda, Kosei Maemura and Shoji Natsugoe

    Citation: World Journal of Surgical Oncology 2018 16:165

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  6. Content type: Case report

    Pleuroblastoma (PPB) is a rare pediatric tumor which, in 30% of cases, is associated with cystic nephroma. It has been recently linked to the DICER1 mutation as part of a predisposition syndrome for various tu...

    Authors: Olivier Abbo, Kalitha Pinnagoda, Laurent Brouchet, Bertrand Leobon, Frédérique Savagner, Isabelle Oliver, Philippe Galinier, Marie-Pierre Castex and Marlène Pasquet

    Citation: World Journal of Surgical Oncology 2018 16:164

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  7. Content type: Research

    This research aimed to investigate whether metabolic syndrome (MetS) and non-alcoholic fatty liver disease (NAFLD) had both individual and synergistic effects on the prognosis for female colorectal carcinoma (...

    Authors: Zhou-Feng Chen, Xiu-Li Dong, Qing-Ke Huang, Wang-Dong Hong, Wen-Zhi Wu, Jian-Sheng Wu and Shuang Pan

    Citation: World Journal of Surgical Oncology 2018 16:163

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  8. Content type: Research

    Soft tissue sarcomas (STS) are rare malignant tumors. The efficacy of preoperative chemotherapy for STS is evaluated using various tumor size-based radiological response criteria. However, it is still unclear ...

    Authors: Kazuhiro Tanaka, Gakuto Ogawa, Junki Mizusawa, Norifumi Naka, Akira Kawai, Mitsuru Takahashi, Toru Hiruma, Yoshihiro Matsumoto, Hiroyuki Tsuchiya, Robert Nakayama, Hiroshi Hatano, Makoto Emori, Masami Hosaka, Yukihiro Yoshida, Junya Toguchida, Satoshi Abe…

    Citation: World Journal of Surgical Oncology 2018 16:162

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  9. Content type: Research

    Giant cell tumor of bone (GCTB) is an intermediate tumor known to be locally aggressive, but rarely metastasizing. To plan a prospective study of GCTB, we performed a questionnaire survey for institutions part...

    Authors: Hiroshi Urakawa, Tsukasa Yonemoto, Seiichi Matsumoto, Tatsuya Takagi, Kunihiro Asanuma, Munenori Watanuki, Akira Takemoto, Norifumi Naka, Yoshihiro Matsumoto, Akira Kawai, Toshiyuki Kunisada, Tadahiko Kubo, Makoto Emori, Hiroaki Hiraga, Hiroshi Hatano, Satoshi Tsukushi…

    Citation: World Journal of Surgical Oncology 2018 16:160

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  10. Content type: Research

    Patient Blood Management (PBM) is a systematic quality improving clinical model to reduce anemia and avoid transfusions in all kinds of clinical settings. Here, we investigated the potential of PBM in oncologi...

    Authors: Vivienne Keding, Kai Zacharowski, Wolf O. Bechstein, Patrick Meybohm and Andreas A. Schnitzbauer

    Citation: World Journal of Surgical Oncology 2018 16:159

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  11. Content type: Case report

    Pancreatic acinar cell carcinoma (PACC), a rare variant of pancreatic malignancy, is generally managed the same way as pancreatic ductal adenocarcinoma (PDAC). Surgical resection is the gateway to curing it; h...

    Authors: Yusuke Ohara, Tatsuya Oda, Tsuyoshi Enomoto, Katsuji Hisakura, Yoshimasa Akashi, Koichi Ogawa, Yohei Owada, Yu Domoto, Yoshihiro Miyazaki, Osamu Shimomura, Masanao Kurata and Nobuhiro Ohkohchi

    Citation: World Journal of Surgical Oncology 2018 16:158

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  12. Content type: Review

    The ideal level of ligation of the inferior mesenteric artery (IMA) during curative resection of sigmoid colon and rectal cancer is still controversial. The aim of this meta-analysis was to examine the impact ...

    Authors: Jinshui Zeng and Guoqiang Su

    Citation: World Journal of Surgical Oncology 2018 16:157

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  13. Content type: Research

    To investigate the importance of adjuvant chemotherapy in locally advanced rectal cancer (≥ cT3 or N+) staged ypT0–2 ypN0 on final histological work-up after neoadjuvant chemoradiation and radical resection.

    Authors: Christian Galata, Kirsten Merx, Sabine Mai, Timo Gaiser, Frederik Wenz, Stefan Post, Peter Kienle, Ralf-Dieter Hofheinz and Karoline Horisberger

    Citation: World Journal of Surgical Oncology 2018 16:156

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  14. Content type: Case report

    Epidermal cysts and squamous cell carcinomas (SCCs) are common skin lesions. However, a malignant change in an epidermal cyst is very rare. The incidence of a malignant change from an epidermal cyst to cutaneo...

    Authors: Byung-Soo Park, Dong Hoon Shin, Soo-Hong Kim, Hyuk Jae Jung, Gyung Mo Son and Hyun Sung Kim

    Citation: World Journal of Surgical Oncology 2018 16:155

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  15. Content type: Case report

    Neuroendocrine tumors (NETs) of the gallbladder are rare and generally considered low-grade malignancies. We herein describe a case of a patient with a 0.8-cm clear cell NET G1 of the gallbladder with nodal in...

    Authors: Yuki Hirose, Jun Sakata, Kazuhiko Endo, Masato Takahashi, Reijiro Saito, Hiroshi Imano, Tomoki Kido, Kei Yoshino, Toshiki Sasaki and Toshifumi Wakai

    Citation: World Journal of Surgical Oncology 2018 16:150

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  16. Content type: Research

    The repair and reconstruction of maxillary and mandibular extensive defects have put huge challenges to surgeons. The fibular free flap (FFF) is one of the standard treatment choices for reconstruction. The co...

    Authors: Youkang Ni, Ping Lu, Zhi Yang, Wenlong Wang, Wei Dai, Zhong-zheng Qi, Weiyi Duan, Zhong-fei Xu, Chang-fu Sun and Fayu Liu

    Citation: World Journal of Surgical Oncology 2018 16:149

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  17. Content type: Case report

    The clinical findings of early anal gland carcinoma (AGC) have not been well delineated because AGC is a rare malignancy usually diagnosed at an advanced stage. Knowledge of the characteristic findings will be...

    Authors: Mikito Mori, Keiji Koda, Atsushi Hirano, Kiyohiko Shuto, Chihiro Kosugi, Kazuo Narushima, Isamu Hosokawa, Takayuki Suzuki, Masato Yamazaki and Hiroaki Shimizu

    Citation: World Journal of Surgical Oncology 2018 16:148

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  18. Content type: Research

    In here, we evaluated pattern of metastasis and cross-compared clinicopathological features between different age groups with breast cancer (BC).

    Authors: Majid Akrami, Afrooz Sepahdar, Peyman Arasteh, Sedigheh Tahmasebi, Vahid Zangouri, Azam Askari, Babak Pezeshki and Abdolrasoul Talei

    Citation: World Journal of Surgical Oncology 2018 16:147

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  19. Content type: Research

    The multidisciplinary team (MDT) discussion has earned increasing popularity for the delivery of cancer care. However, MDT meeting (MDTM) is time and resource intensive, and some efforts to optimize discussion...

    Authors: Yujie Yuan, Jinning Ye, Yufeng Ren, Weigang Dai, Jianjun Peng, Shirong Cai, Chuangqi Chen, Min Tan, Wu Song and Yulong He

    Citation: World Journal of Surgical Oncology 2018 16:146

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  20. Content type: Research

    Diffusion-weighted imaging (DWI) is suggested as an non-invasive and non-radioactive imaging modality in the identification of pathological complete response (pCR) in breast cancer patients receiving neoadjuva...

    Authors: Wen Gao, Ning Guo and Ting Dong

    Citation: World Journal of Surgical Oncology 2018 16:145

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  21. Content type: Review

    Dose-dense chemotherapy is a widely accepted regimen for high-risk breast cancer patients. However, conflicting survival benefits of pure dose-dense chemotherapy have been reported in different randomized cont...

    Authors: Wenqi Zhou, Shizhe Chen, Faliang Xu and Xiaohua Zeng

    Citation: World Journal of Surgical Oncology 2018 16:144

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  22. Content type: Case report

    Gastric cancer is the fifth most prevalent and the third most lethal cancer worldwide, causing approximately 720,000 deaths annually. Although most cases of gastric cancers are sporadic, one of its inherited f...

    Authors: Olsi Gjyshi, Pankaj Vashi, Laura Seewald, Mitra Kohan, Elham Abboud, Eric Fowler, Revathi Suppiah and Hatem Halabi

    Citation: World Journal of Surgical Oncology 2018 16:143

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  23. Content type: Review

    Pancreatic neuroendocrine tumors (PNETs) are rare pancreatic neoplasms. About 40–80% of patients with PNET are metastatic at presentation, usually involving the liver (40–93%). Liver metastasis represents the ...

    Authors: Giuseppe Nigri, Niccolò Petrucciani, Tarek Debs, Livia Maria Mangogna, Anna Crovetto, Giovanni Moschetta, Raffaello Persechino, Paolo Aurello and Giovanni Ramacciato

    Citation: World Journal of Surgical Oncology 2018 16:142

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  24. Content type: Research

    The optimal treatment for locally advanced esophageal squamous cell carcinoma remains unclear. We compared the clinical outcomes of neoadjuvant concurrent chemoradiotherapy (CCRT) followed by esophagectomy [th...

    Authors: Chih-Yi Chen, Chia-Chin Li and Chun-Ru Chien

    Citation: World Journal of Surgical Oncology 2018 16:141

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  25. Content type: Research

    We report our experience and outcomes about the management of Askin’s tumors [AT], which are rare primitive neuroectodermal tumors (PNETs) that develop within the soft tissue of the thoracopulmonary region, ty...

    Authors: Silvia Triarico, Giorgio Attinà, Palma Maurizi, Stefano Mastrangelo, Lorenzo Nanni, Vito Briganti, Elisa Meacci, Stefano Margaritora, Mario Balducci and Antonio Ruggiero

    Citation: World Journal of Surgical Oncology 2018 16:140

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    The Correction to this article has been published in World Journal of Surgical Oncology 2018 16:193

  26. Content type: Research

    Enchondromas and atypical cartilaginous tumors (ACT) are often located at the proximal humerus. Most lesions can be followed conservatively, but surgical resection may alleviate pain, avoid pathological fractu...

    Authors: Georg W. Omlor, Vera Lohnherr, Jessica Lange, Simone Gantz, Christian Merle, Joerg Fellenberg, Patric Raiss and Burkhard Lehner

    Citation: World Journal of Surgical Oncology 2018 16:139

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  27. Content type: Research

    Diffusion-weighted imaging (DWI) and apparent diffusion coefficient (ADC) values as imaging biomarkers of rectal cancer are currently a hot research spot. The use of ADC values for preoperative judgment of pat...

    Authors: Cui Tang, Mou-bin Lin, Jin-lei Xu, Lan-hua Zhang, Xiao-ming Zuo, Zhong-shuai Zhang, Meng-xiao Liu and Jin-ming Xu

    Citation: World Journal of Surgical Oncology 2018 16:138

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  28. Content type: Research

    Whether serum magnesium levels were lower in patients with lung cancer than that in healthy controls is controversial. The aim of this study was to identify and synthesize all citations evaluating the relation...

    Authors: Xinghui Song, Xiaoning Zhong, Kaijiang Tang, Gang Wu and Yin Jiang

    Citation: World Journal of Surgical Oncology 2018 16:137

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  29. Content type: Research

    There has been worldwide debate on lymphadenectomy for gastric cancer, with increasing consensus on performing an extended (D2) resection. There is a paucity of data in Australia. Our aim is to compare overall...

    Authors: Susanna Lam, Elinor Tan, Audrey Menezes, David Martin, James Gallagher, David Storey and Charbel Sandroussi

    Citation: World Journal of Surgical Oncology 2018 16:136

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  30. Content type: Research

    To clarify if diagnostic ureteroscopy (URS) before radical nephroureterectomy for patients with upper tract urothelial carcinoma (UTUC) will increase the risk of intravesical recurrence.

    Authors: Hsiang-Ying Lee, Hsin-Chih Yeh, Wen-Jeng Wu, Jiun-Shiuan He, Chun-Nung Huang, Hung-Lung Ke, Wei-Ming Li, Chien-Feng Li and Ching-Chia Li

    Citation: World Journal of Surgical Oncology 2018 16:135

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  31. Content type: Research

    The optimal preoperative bowel preparation for colorectal surgery remains controversial. However, recent studies have established that bowel preparation varies significantly among countries and even surgeons a...

    Authors: Zheng Liu, Ming Yang, Zhi-xun Zhao, Xu Guan, Zheng Jiang, Hai-peng Chen, Song Wang, Ji-chuan Quan, Run-kun Yang and Xi-shan Wang

    Citation: World Journal of Surgical Oncology 2018 16:134

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  32. Content type: Technical innovations

    In order to overcome the shortcomings of laparoscopic intersphincteric resection (Lap ISR), an alternative method of delivering intraoperative radiotherapy by Intrabeam X-rays radiotherapy system (XRS) is prop...

    Authors: Min Wang, Wangsheng Xue, Zeyun Zhao, Yongbo Li, Xinyu Wang, Tao Li, Yongbo Zou, Xiaowei Song, Mingwei Zhang, Tiejun Wang, Jianzheng Yang, Chunyu Wang and Shuang Wang

    Citation: World Journal of Surgical Oncology 2018 16:133

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  33. Content type: Research

    Inflammation-induced endothelial precursor cell recruitment and angiogenesis are thought to be associated with CXCL16-CXCR6 pair activity. This study’s main purpose was to determine plasma CXCL16 levels after ...

    Authors: H. M. C. Shantha Kumara, Erica Pettke, Abhinit Shah, Xiaohong Yan, Vesna Cekic, Melissa Alvarez Downing, Nipa Dilip Gandhi and Richard L. Whelan

    Citation: World Journal of Surgical Oncology 2018 16:132

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  34. Content type: Research

    Recently, molecule-targeting and bone-modifying agents have improved the treatment outcomes of lung cancer-derived metastatic spine tumors. Therefore, the prognostic factors for such tumors were examined, and ...

    Authors: Hiroshi Uei and Yasuaki Tokuhashi

    Citation: World Journal of Surgical Oncology 2018 16:131

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  35. Content type: Review

    Thyroid and breast cancer are two of the malignant diseases with highest incidence in females. Based on clinical experience, breast and thyroid cancer often occur metachronously or synchronously. Therefore, th...

    Authors: Liangbo Dong, Jun Lu, Bangbo Zhao, Weibin Wang and Yupei Zhao

    Citation: World Journal of Surgical Oncology 2018 16:130

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  36. Content type: Research

    Pakistan’s population is ethnically diverse with distinct ethnic groups inhabiting various parts of the country. Cancer statistics obtained from specific regions populated by distinct ethnic groups may vary co...

    Authors: Romana Idrees, Saira Fatima, Jamshid Abdul-Ghafar, Ahmad Raheem and Zubair Ahmad

    Citation: World Journal of Surgical Oncology 2018 16:129

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  37. Content type: Research

    The incidence, site distribution, and mortality rates of patients with colorectal cancer differ according to gender. We investigated gene mutations in colorectal patients and wanted to examine gender-specific ...

    Authors: Yi-Jian Tsai, Sheng-Chieh Huang, Hung-Hsin Lin, Chun-Chi Lin, Yuan-Tzu Lan, Huann-Sheng Wang, Shung-Haur Yang, Jeng-Kai Jiang, Wei-Shone Chen, Tzu-chen Lin, Jen-Kou Lin and Shih-Ching Chang

    Citation: World Journal of Surgical Oncology 2018 16:128

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  38. Content type: Research

    HIF-1alpha and CAIX proteins are commonly expressed under hypoxic conditions, but other regulatory factors have been described as well. Pancreatic ductal adenocarcinoma (PDAC) is characterized by hypoxia and s...

    Authors: Joni Leppänen, Olli Helminen, Heikki Huhta, Joonas H. Kauppila, Joel Isohookana, Kirsi-Maria Haapasaari, Seppo Parkkila, Juha Saarnio, Petri P. Lehenkari and Tuomo J. Karttunen

    Citation: World Journal of Surgical Oncology 2018 16:127

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  39. Content type: Research

    This study aims to explore the feasibility of narrow-band imaging (NBI) applied for the diagnostic screening of a high-risk population of nasopharyngeal carcinoma (NPC) and increase the accuracy rate of nasoph...

    Authors: Yong-Feng Si, Zhuo-Xia Deng, Jing-Jin Weng, Jin-Yuan Si, Gui-Ping Lan, Ben-Jian Zhang, Yong Yang, Bo Huang, Xing Han, Ying Qin, Yang-Da Qin, Wei-Ming Xiong and Bing Li

    Citation: World Journal of Surgical Oncology 2018 16:126

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  40. Content type: Review

    Schwannomas of the colon and rectum are rare among gastrointestinal schwannomas. They are usually discovered incidentally as a submucosal mass on routine colonoscopy and diagnosed on pathologic examination of ...

    Authors: Ali Bohlok, Melody El Khoury, Anne Bormans, Maria Gomez Galdon, Michael Vouche, Issam El Nakadi, Vincent Donckier and Gabriel Liberale

    Citation: World Journal of Surgical Oncology 2018 16:125

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  41. Content type: Review

    Although numerous studies have shown that positive surgical margin (PSM) is linked to biochemical recurrence (BCR) in prostate cancer (PCa), the research results have been inconsistent. This study aimed to exp...

    Authors: Lijin Zhang, Bin Wu, Zhenlei Zha, Hu Zhao, Yuefang Jiang and Jun Yuan

    Citation: World Journal of Surgical Oncology 2018 16:124

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  42. Content type: Case report

    The ethical implications of the utilization of kidneys with solid renal masses (SRMs) in transplantation are the subject of lively debate in the transplantation community and beyond. One of such implications i...

    Authors: Duilio Pagano, Fabrizio di Francesco, Liotta Rosa, Chibueze A. Nwaiwu, Sergio Li Petri and Salvatore Gruttadauria

    Citation: World Journal of Surgical Oncology 2018 16:123

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  43. Content type: Research

    Docetaxel, cisplatin, and 5-fluorouracil (DCF) therapy can cause severe adverse events, including neutropenia and febrile neutropenia. The feasibility of DCF therapy is a concern, particularly for elderly pati...

    Authors: Yuji Akiyama, Akira Sasaki, Fumitaka Endo, Haruka Nikai, Satoshi Amano, Akira Umemura, Shigeaki Baba, Takehiro Chiba, Toshimoto Kimura, Takeshi Takahara, Hiroyuki Nitta, Koki Otsuka, Masaru Mizuno, Yusuke Kimura, Keisuke Koeda and Takeshi Iwaya

    Citation: World Journal of Surgical Oncology 2018 16:122

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  44. Content type: Review

    Inflammatory bowel disease (IBD), which includes ulcerative colitis (UC) and Crohn’s disease (CD), is a chronic, idiopathic, repeated inflammatory disease. Colorectal cancer (CRC) that develops in patients wit...

    Authors: Hitoshi Kameyama, Masayuki Nagahashi, Yoshifumi Shimada, Yosuke Tajima, Hiroshi Ichikawa, Masato Nakano, Jun Sakata, Takashi Kobayashi, Sumana Narayanan, Kazuaki Takabe and Toshifumi Wakai

    Citation: World Journal of Surgical Oncology 2018 16:121

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  45. Content type: Technical innovations

    Our article describes our experience with using a frontal axial pattern flap combined with hard palate mucosa transplant to reconstruct midfacial defects after the excision of huge basal cell carcinoma.

    Authors: Junliang Wu, Yong Qing, Ying Cen and Junjie Chen

    Citation: World Journal of Surgical Oncology 2018 16:120

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  46. Content type: Research

    In this study, we intend to determine the immunohistochemical expression of EGFR in cases of head and neck squamous cell carcinoma and its association with prognostic clinico-pathologic features.

    Authors: Atif Ali Hashmi, Zubaida Fida Hussain, Saher Aijaz, Muhammad Irfan, Erum Yousuf Khan, Samreen Naz, Naveen Faridi, Amir Khan and Muhammad Muzzammil Edhi

    Citation: World Journal of Surgical Oncology 2018 16:118

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