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  1. Content type: Research

    There are few reports about the factor influencing the prognosis of high-grade neuroendocrine carcinoma. In this study, we evaluated surgical outcome of clinical stage I high-grade neuroendocrine carcinoma.

    Authors: Eisuke Mochizuki, Shun Matsuura, Kyohei Oishi, Koichi Miyashita, Koshiro Ichijyo, Syunya Furukawa, Miyuki Nagaoka, Shinichiro Mikura, Masaru Tsukui, Naoki Koshimizu, Shogo Sakurai, Kazuhiro Asada and Toshihiro Shirai

    Citation: World Journal of Surgical Oncology 2018 16:33

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  2. Content type: Research

    SH3-containing guanine nucleotide exchange factor (SGEF), a RhoG-specific guanine nucleotide exchange factor (GEF), was consider as a key signal that determines cancer cell invasion. Although SGEF has been con...

    Authors: Qian Chen, Xiao Lu, Quan-Xing Liu, Dong Zhou, Yuan Qiu, Ji-Gang Dai and Hong Zheng

    Citation: World Journal of Surgical Oncology 2018 16:32

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  3. Content type: Research

    The objective of this study was to examine the effectiveness and safety of lower pole (LP) approach in retroperitoneal laparoscopic radical nephrectomy (LRN).

    Authors: Bo Yuan, Yuantao Wang, Jialin Gao, Yongrui Zhang, Yaowen Fu and Wei An

    Citation: World Journal of Surgical Oncology 2018 16:31

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  4. Content type: Research

    In the latest years, a lot of research studies regarding the usage of active agents from plants in the treatment of tumors have been published, but there is no data about successful usage of herbal remedies in...

    Authors: Ivo Trogrlić, Dragan Trogrlić, Darko Trogrlić and Amina Kadrić Trogrlić

    Citation: World Journal of Surgical Oncology 2018 16:28

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  5. Content type: Case Report

    Esophageal schwannomas are rare esophageal submucosal tumors. We herein report a case of a lobulated esophageal schwannoma resected with concurrent approach from the thorax and cervix.

    Authors: Yoshinori Iwata, Chihiro Tanaka, Shuji Komori, Narutoshi Nagao, Masahiko Kawai, Kazuhiro Yoshida and Katsuyuki Kunieda

    Citation: World Journal of Surgical Oncology 2018 16:29

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  6. Content type: Research

    Cervical lymph node metastasis of papillary thyroid carcinoma (PTC) is common. However, whether undergoing prophylactic central lymph node (CLN) dissection or lateral lymph node (LLN) dissections to prevent me...

    Authors: Daixing Hu, Jing Zhou, Wei He, Jie Peng, Yijia Cao, Haoyu Ren, Yu Mao, Yi Dou, Wei Xiong, Qi Xiao and Xinliang Su

    Citation: World Journal of Surgical Oncology 2018 16:30

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  7. Content type: Research

    Although the prognosis for operable breast cancers is reportedly worse if serum carcinoembryonic antigen (CEA) and cancer antigen 15-3 (CA15-3) levels are above normal, the usefulness of this prognosis is limi...

    Authors: Michiko Imamura, Takashi Morimoto, Takashi Nomura, Shintaro Michishita, Arisa Nishimukai, Tomoko Higuchi, Yukie Fujimoto, Yoshimasa Miyagawa, Ayako Kira, Keiko Murase, Kazuhiro Araki, Yuichi Takatsuka, Koshi Oh, Yoshikazu Masai, Kouhei Akazawa and Yasuo Miyoshi

    Citation: World Journal of Surgical Oncology 2018 16:26

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  8. Content type: Research

    Nutritional deficits, cachexia, and sarcopenia are extremely common in esophageal cancer. The aim of this article was to assess the effect of loss of skeletal muscle mass during neoadjuvant treatment on the pr...

    Authors: Tommi Järvinen, Ilkka Ilonen, Juha Kauppi, Jarmo Salo and Jari Räsänen

    Citation: World Journal of Surgical Oncology 2018 16:27

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  9. Content type: Research

    This study aimed to propose a new surgical strategy, i.e., the transcervical video-assisted mediastinoscopic lymphadenectomy (VAMLA) with esophagectomy via the left transthoracic approach for patients with eso...

    Authors: Xu Li, Wenxiang Wang, Yong Zhou, Desong Yang, Jie Wu, Baihua Zhang, Zhining Wu and Jinming Tang

    Citation: World Journal of Surgical Oncology 2018 16:25

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  10. Content type: Research

    Although liver resection (LR) provides the best chance of long-term survival for patients with colorectal cancer (CRC) hepatic metastasis, concerns regarding chemotherapy before liver resection remain unresolved.

    Authors: Kun-Ming Chan, Tsung-Han Wu, Yu-Chao Wang, Chen-Fang Lee, Ting-Jung Wu, Hong-Shiue Chou, Wei-Chen Lee, Jy-Ming Chiang and Jinn-Shiun Chen

    Citation: World Journal of Surgical Oncology 2018 16:24

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  11. Content type: Case report

    Sunitinib is a multiple receptor tyrosine kinase inhibitor (TKI) used for the treatment of renal cell carcinoma (RCC). It increases the median survival considerably with minimum side effects. Alopecia is one o...

    Authors: Manoj Pandey, Mahendran Ramasamy and Mridula Shukla

    Citation: World Journal of Surgical Oncology 2018 16:23

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  12. Content type: Research

    To examine the clinical value of miR-198-5p in lung squamous cell carcinoma (LUSC).

    Authors: Yue-ya Liang, Jia-cheng Huang, Rui-xue Tang, Wen-jie Chen, Peng Chen, Wei-luan Cen, Ke Shi, Li Gao, Xiang Gao, An-gui Liu, Xiao-tong Peng, Gang Chen, Su-ning Huang, Ye-ying Fang and Yong-yao Gu

    Citation: World Journal of Surgical Oncology 2018 16:22

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  13. Content type: Case Report

    Patients with advanced gastric cancer (GC) may ultimately die because GC mostly leads to synchronous or metachronous metastasis. However, colonic metastasis of GC is extremely rare. According to a PubMed searc...

    Authors: Wei-Chih Su, Hsiang-Lin Tsai, Chun-Chieh Wu, Shan-Yin Tsai, Yung-Sung Yeh, Cheng-Jen Ma and Jaw-Yuan Wang

    Citation: World Journal of Surgical Oncology 2018 16:21

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  14. Content type: Research

    Head and neck cancers are the commonest cancer in Southeast Asia. Despite being a surface cancer, it is associated with significant morbidity as despite early detection by the patients they often report for tr...

    Authors: Manoj Pandey, Krishna Kiran Kannepali, Ruhi Dixit and Mohan Kumar

    Citation: World Journal of Surgical Oncology 2018 16:20

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  16. Content type: Research

    The objective of this study is to analyze the treatment outcome and secondary reactions in 98 patients with stage I–III cervical carcinoma who underwent postoperative radiotherapy.

    Authors: Yan-Mei Liu, Ling-Qin Ni, Sai-Sai Wang, Qian-Ling Lv, Wei-Jun Chen and Shen-Peng Ying

    Citation: World Journal of Surgical Oncology 2018 16:18

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  19. Content type: Case Report

    Intracystic papillary carcinoma (IPC) is defined as cancer that develops from the wall of a cyst in the breast. As breast cancer in men accounts for only 1% of all breast cancers, male IPC is an extremely rare...

    Authors: Haruhito Kinoshita, Shinichiro Kashiwagi, Hitoshi Teraoka, Takuya Mori, Kenji Kuroda, Mikio Nanbara, Eiji Noda, Takaaki Chikugo, Kosei Hirakawa and Masaichi Ohira

    Citation: World Journal of Surgical Oncology 2018 16:15

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  20. Content type: Research

    Chondroblastoma is a rare benign cartilaginous tumor, which primarily occurs in children and adolescents. Chondroblastoma commonly originates in the epiphyseal plate of long bones. An aggressive curettage trea...

    Authors: Yan Xiong, Yun Lang, Zeping Yu, Hongyuan Liu, Xiang Fang, Chongqi Tu and Hong Duan

    Citation: World Journal of Surgical Oncology 2018 16:14

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  21. Content type: Research

    The presence of peripheral circulating tumor cells indicates the possible existence of a tumor in vivo; however, low numbers of circulating tumor cells (CTCs) can be detected in peripheral blood of healthy ind...

    Authors: Chengguang Yang, Wenfang Zhuang, Yuemei Hu and Leiming Zhu

    Citation: World Journal of Surgical Oncology 2018 16:13

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  23. Content type: Research

    This study investigated UGP2 (uridine diphosphate-glucose pyrophosphorylase-2) and CFL1 (cofilin-1) expression in pancreatic ductal carcinoma (PDC), paracancerous tissue (PT), benign lesions (BL), and normal t...

    Authors: Lingxiang Wang, Li Xiong, Zhengchun Wu, Xiongying Miao, Ziru Liu, Daiqiang Li, Qiong Zou and Zhulin Yang

    Citation: World Journal of Surgical Oncology 2018 16:11

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  24. Content type: Research

    Laparoscopic radical cystectomy (LRC) has been shown to have less estimated blood loss (EBL), transfusion rate, narcotic analgesic requirement, earlier return of bowel function, and shorter hospital stay. The ...

    Authors: Xiaosong Wei, Jinjin Lu, Khurram Mutahir Siddiqui, Fan Li, Qianyuan Zhuang, Weimin Yang, Zhiquan Hu, Zhong Chen, Xiaodong Song, Shaogang Wang and Zhangqun Ye

    Citation: World Journal of Surgical Oncology 2018 16:10

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  25. Content type: Research

    M2-polarized macrophages are tumor-associated-macrophages (TAMs), which are important contents of tumor-infiltrating immune cells. Toll-like receptor 4 (TLR4) is a molecular biomarker of tumor aggressiveness a...

    Authors: Rong-Rong Yao, Jing-Huan Li, Rui Zhang, Rong-Xin Chen and Yan-Hong Wang

    Citation: World Journal of Surgical Oncology 2018 16:9

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  26. Content type: Review

    Induction chemotherapy has been shown to improve survival of patients with stage III A/N2 (T1–3, N2, M0) non-small cell lung cancer (NSCLC), followed by resection, but the benefits of neoadjuvant radiotherapy ...

    Authors: Yuqiao Chen, Xiong Peng, Yuan Zhou, Kun Xia and Wei Zhuang

    Citation: World Journal of Surgical Oncology 2018 16:8

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  27. Content type: Review

    Fibrous dysplasia is a slowly progressive benign fibro-osseous disorder that involves one or multiple bones with a unilateral distribution in most cases. It is a lesion of unknown etiology, uncertain pathogene...

    Authors: Józef Mierzwiński, Justyna Kosowska, Justyna Tyra, Karolina Haber, Maria Drela, Dariusz Paczkowski and Paweł Burduk

    Citation: World Journal of Surgical Oncology 2018 16:5

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  28. Content type: Research

    Indications for restaging transurethral resection of the bladder tumor (reTURBT) in patients with non-muscle-invasive bladder cancer (NMIBC) remain controversial. This study was aimed at evaluation of clinical...

    Authors: Piotr Zapała, Bartosz Dybowski, Sławomir Poletajew, Łukasz Białek, Andrzej Niewczas and Piotr Radziszewski

    Citation: World Journal of Surgical Oncology 2018 16:6

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  30. Content type: Research

    Male breast cancer is a rare and less known disease. Therapeutic modalities affect survival. In Burkina Faso, male breast cancers are diagnosed in everyday practice, but the prognosis at short-, middle-, and l...

    Authors: Nayi Zongo, Smaïla Ouédraogo, Nina Korsaga-Somé, Ollo Roland Somé, Naïma GO, Edgar Ouangré, Maurice Zida, Gilbert Bonkoungou, Aimé Sosthène Ouédraogo, Aboubacar Hirrum Bambara, Bambara Augustin Tozoula, Si Simon Traoré, Ahmadou Dem, Pascal Niamba, Adama Traoré, Adama Sanou…

    Citation: World Journal of Surgical Oncology 2018 16:4

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  31. Content type: Research

    Performance status (PS) is known as one of the strongest prognostic factors for survival in metastatic colorectal cancer patients. The aim of the present study was to analyze factors associated with poor PS as...

    Authors: Peter Strandberg Holka, Sam Eriksson, Jakob Eberhard, Magnus Bergenfeldt, Gert Lindell and Christian Sturesson

    Citation: World Journal of Surgical Oncology 2018 16:3

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  32. Content type: Review

    We performed an umbrella review of systematic reviews summarizing the evidence on the Harmonic scalpel (HS) compared with conventional techniques in surgical oncology (including lymph node dissection).

    Authors: Hang Cheng, Jeffrey W. Clymer, Behnam Sadeghirad, Nicole C. Ferko, Chris G. Cameron and Joseph F. Amaral

    Citation: World Journal of Surgical Oncology 2018 16:2

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  33. Content type: Research

    Prognosis of breast cancer and success of therapeutic interventions largely rely on the clinico-pathologic and biological characteristics of the tumor and vary due to the heterogeneous nature of breast cancers...

    Authors: Atif Ali Hashmi, Saher Aijaz, Saadia Mehmood Khan, Raeesa Mahboob, Muhammad Irfan, Narisa Iftikhar Zafar, Mariam Nisar, Maham Siddiqui, Muhammad Muzzammil Edhi, Naveen Faridi and Amir Khan

    Citation: World Journal of Surgical Oncology 2018 16:1

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  35. Content type: Case Report

    Carcinoembryonic antigen (CEA) is one of the most widely used tumor markers, and its value in the surveillance of post-operative colorectal cancer is well established. Fluorodeoxyglucose-positron emission tomo...

    Authors: Shih-Wei Chen and Yen-Kung Chen

    Citation: World Journal of Surgical Oncology 2017 15:230

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  36. Content type: Review

    The aim of this study was to compare the short-term and mid-term effects of laparoscopic intersphincteric resection with the conventional open approach for patients with low rectal cancer through a meta-analysis.

    Authors: Hanyu Chen, Bin Ma, Peng Gao, Hongchi Wang, Yongxi Song, Linhao Tong, Peiwen Li and Zhenning Wang

    Citation: World Journal of Surgical Oncology 2017 15:229

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  37. Content type: Research

    Recently, total pelvic floor reconstruction (TR) has been the treatment of choice for improving urinary incontinence (UI) after radical prostatectomy (RP). However, the superiority of TR with respect to urinar...

    Authors: Yu-Peng Wu, Ning Xu, Shi-Tao Wang, Shao-Hao Chen, Yun-Zhi Lin, Xiao-Dong Li, Qing-Shui Zheng, Yong Wei and Xue-Yi Xue

    Citation: World Journal of Surgical Oncology 2017 15:228

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  38. Content type: Research

    The presence of microvascular invasion (McVI) in hepatocellular carcinoma (HCC) has been proposed as a cause of recurrence and poor survival, although this has not been officially emphasized in staging systems...

    Authors: Yong Keun Park, Sung Kyu Song, Bong-Wan Kim, Seung-Keun Park, Chul-Woon Chung and Hee-Jung Wang

    Citation: World Journal of Surgical Oncology 2017 15:225

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  39. Content type: Research

    It is generally accepted that an insufficient future liver remnant is a major limitation of large-scale hepatectomy for patients with primary hepatocellular carcinoma. Conventional two-stage hepatectomy (TSH) ...

    Authors: Zheng Zhou, Mingxing Xu, Nan Lin, Chuzhi Pan, Boxuan Zhou, Yuesi Zhong and Ruiyun Xu

    Citation: World Journal of Surgical Oncology 2017 15:227

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  41. Content type: Research

    Statins are the backbone of lipid-lowering therapy and are among the most commonly prescribed drugs in the elderly population in Sweden today. Colorectal cancer is the second most common cancer in men and wome...

    Authors: David Renman, Erik Lundberg, Ulf Gunnarsson and Karin Strigård

    Citation: World Journal of Surgical Oncology 2017 15:222

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  42. Content type: Correspondence

    Several recent studies provide evidence that D-dimer (DD) concentration in peripheral blood correlates negatively with overall survival (OS) in patients with pancreatic ductal adenocarcinoma (PDAC). Contrarily...

    Authors: Adam Durczynski, Aleksander Skulimowski, Piotr Hogendorf, Dariusz Szymanski, Anna Kumor, Konrad Marski, Siri Øvereng Juliebø, Grazyna Poznanska and Janusz Strzelczyk

    Citation: World Journal of Surgical Oncology 2017 15:223

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  43. Content type: Research

    New systemic chemotherapy agents have improved prognosis in patients with colorectal liver metastases (CLM), but some of them damage the liver parenchyma and ultimately increase postoperative morbidity and mor...

    Authors: Amalia Pelegrina, Josep Martí, Rosa Miquel, Joana Ferrer, Virginia Hernández-Gea, Alba Diaz, Cristina Nadal, Juan Carlos García-Valdecasas and Josep Fuster

    Citation: World Journal of Surgical Oncology 2017 15:224

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  44. Content type: Case Report

    Gastrointestinal stromal tumors (GISTs) rarely present with predominantly cystic changes. Here, we report a case of giant GIST of the stomach with predominantly cystic changes in a 74-year-old female patient.

    Authors: Liying Wang, Libin Liu, Zhaohui Liu, Yueli Tian and Zhe Lin

    Citation: World Journal of Surgical Oncology 2017 15:220

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  45. Content type: Case Report

    Single soft tissue metastasis of medullary thyroid carcinoma is extremely rare. In addition, several occult medullary thyroid carcinomas with distant metastasis were reported, but undetectable primary lesion a...

    Authors: Masanori Okamoto, Akira Takazawa, Kaoru Aoki, Yasuo Yoshimura, Hiroyuki Kato, Toshiaki Otsuki, Kazuma Maeno and Tomonobu Koizumi

    Citation: World Journal of Surgical Oncology 2017 15:221

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  46. Content type: Case Report

    Sarcomatoid hepatocellular carcinoma (SHC) is a rare malignant hepatic tumor. Recurrent interventional therapies such as transcatheter arterial chemo-embolization (TACE), radiofrequency ablation (RFA), and per...

    Authors: Yingying Yu, Yanping Zhong, Jingyu Wang and Di Wu

    Citation: World Journal of Surgical Oncology 2017 15:219

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  47. Content type: Research

    Risk-reducing bilateral salpingo-oophorectomy (RRBSO) increases survival in patients at high risk of developing ovarian cancer. While many general gynecologists perform this procedure, some argue it should be ...

    Authors: Dominique R. Malacarne, Leslie R. Boyd, Yang Long and Stephanie V. Blank

    Citation: World Journal of Surgical Oncology 2017 15:218

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  48. Content type: Case Report

    Metastatic cardiac tumors may cause different symptoms including angina, symptoms of heart failure and/or arrhythmia. In patients with concomitant coronary artery disease, it may be difficult to distinguish be...

    Authors: Angela Kornberger, Tillmann Emrich, Andres Beiras-Fernandez and Christian-Friedrich Vahl

    Citation: World Journal of Surgical Oncology 2017 15:217

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  49. Content type: Research

    The purpose of this case series is to investigate the relationship between splenic thickness (ST) and postoperative outcomes after hepatic resection in hepatitis B virus (HBV)-associated hepatocellular carcino...

    Authors: Xiang Chen, Heng Zou, Li Xiong, Sheng-Fu Huang, Xiong-Ying Miao and Yu Wen

    Citation: World Journal of Surgical Oncology 2017 15:216

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