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  1. Although completion lobectomy is the treatment of choice for local recurrence of non-small cell lung cancer after segmentectomy, few cases have been reported. We report four patients who underwent completion l...

    Authors: Shigeki Suzuki, Keisuke Asakura, Kyohei Masai, Kaoru Kaseda, Tomoyuki Hishida and Hisao Asamura

    Citation: World Journal of Surgical Oncology 2021 19:47

    Content type: Case report

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  2. Thrombocytopenia was reported both detrimental and advantageous to hepatocellular carcinoma (HCC). However, there is little evidence showing clearly the clinical value of preoperative thrombocytopenia on the s...

    Authors: Wei Peng, Chuan Li, Xiaoyun Zhang, Tianfu Wen and Zheyu Chen

    Citation: World Journal of Surgical Oncology 2021 19:46

    Content type: Research

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  3. Neoadjuvant chemotherapy is an important part of the comprehensive treatment of advanced gastric cancer (GC). The effect of neoadjuvant chemotherapy plays a key role in the prognosis of GC patients. Pathologic...

    Authors: Lin Jiang, Zhiqiang Ma, Xin Ye, Weiming Kang and Jianchun Yu

    Citation: World Journal of Surgical Oncology 2021 19:44

    Content type: Research

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  4. Accurate prediction of postoperative pulmonary function is important for ensuring the safety of patients undergoing radical resection for lung cancer. Dynamic perfusion digital radiography is an excellent and ...

    Authors: Jun Hanaoka, Makoto Yoden, Kazuki Hayashi, Takuya Shiratori, Keigo Okamoto, Ryosuke Kaku, Yo Kawaguchi, Yasuhiko Ohshio and Akinaga Sonoda

    Citation: World Journal of Surgical Oncology 2021 19:43

    Content type: Research

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  5. Xpert Bladder Cancer is a detection method developed in recent years, designed with the functions of integrating sample automatically, nucleic acid amplification, and target sequence detection. It is a urine a...

    Authors: Ye-Ling Liu, Xue-Lin Wang, Xiao-Hui Yang, Xiao-Huan Wu, Guo-Xin He, Li-Min Xie, Xun-Jie Cao and Xu-Guang Guo

    Citation: World Journal of Surgical Oncology 2021 19:42

    Content type: Research

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  6. A peritumoral hypointense rim (PTHR) is sometimes observed around hepatocellular carcinoma (HCC) on T2*-weighted images (T2*WIs). We aimed to investigate the association between the PTHR and histopathologic fi...

    Authors: Yoshinori Tsukahara, Yukinori Okajima, Akira Yamada, Masanobu Momose, Takeshi Uehara, Akira Shimizu, Yuji Soejima and Yasunari Fujinaga

    Citation: World Journal of Surgical Oncology 2021 19:41

    Content type: Research

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  7. Intraoperative urinary collecting system entry (CSE) in robot-assisted partial nephrectomy (RAPN) may cause postoperative urinary leakage and extend the hospitalization. Therefore, identifying and firmly closi...

    Authors: Kenichi Nishimura, Yuichiro Sawada, Naoya Sugihara, Keisuke Funaki, Kanae Koyama, Terutaka Noda, Tetsuya Fukumoto, Noriyoshi Miura, Yuki Miyauchi, Tadahiko Kikugawa and Takashi Saika

    Citation: World Journal of Surgical Oncology 2021 19:40

    Content type: Research

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  8. The involvement of circular RNAs (circRNAs) in tamoxifen (TAM) resistance has been identified. Herein, we aimed to identify the role and novel mechanisms of hsa_circ_0025202 in tamoxifen resistance in breast c...

    Authors: Hongjuan Li, Qing Li and Shan He

    Citation: World Journal of Surgical Oncology 2021 19:39

    Content type: Research

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  9. Robotic and laparoscopic surgery for rectal cancer has been applied in the clinic for decades; nevertheless, which surgical approach has a lower rate of postoperative complications is still inconclusive. There...

    Authors: Bo Tang, Xiong Lei, Junhua Ai, Zhixiang Huang, Jun Shi and Taiyuan Li

    Citation: World Journal of Surgical Oncology 2021 19:38

    Content type: Research

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  10. Denosumab (XgevaTM) is a fully human antibody to RANK-Ligand, an important signal mediator in the pathogenesis of giant cell tumour of bone (GCTB). The use of denosumab in the treatment of GCTB has changed the wa...

    Authors: Wolfram Weschenfelder, John M. Abrahams and Luke J. Johnson

    Citation: World Journal of Surgical Oncology 2021 19:37

    Content type: Case report

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  11. Disease sites of female genital tract cancers of BRCA1/2-associated hereditary breast and ovarian cancer (HBOC) are less understood than non-hereditary cancers. We aimed to elucidate the disease site distribution...

    Authors: Takashi Mitamura, Masayuki Sekine, Masami Arai, Yuka Shibata, Momoko Kato, Shiro Yokoyama, Hiroko Yamashita, Hidemichi Watari, Ichiro Yabe, Hiroyuki Nomura, Takayuki Enomoto and Seigo Nakamura

    Citation: World Journal of Surgical Oncology 2021 19:36

    Content type: Correspondence

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  12. Glutamine-fructose-6-phosphate transaminase 1 (GFPT1) is the first rate-limiting enzyme of the hexosamine biosynthesis pathway (HBP), which plays a pivotal role in the progression of pancreatic ductal adenocar...

    Authors: Yitao Gong, Yunzhen Qian, Guopei Luo, Yu Liu, Ruijie Wang, Shengming Deng, He Cheng, Kaizhou Jin, Quanxing Ni, Xianjun Yu, Weiding Wu and Chen Liu

    Citation: World Journal of Surgical Oncology 2021 19:35

    Content type: Research

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  13. The clinical significance of the geriatric nutritional risk index (GNRI) in locally advanced rectal cancer (LARC) patients undergoing preoperative chemoradiotherapy (CRT) followed by curative surgery has not b...

    Authors: Shozo Ide, Yoshinaga Okugawa, Yusuke Omura, Akira Yamamoto, Takashi Ichikawa, Takahito Kitajima, Tadanobu Shimura, Hiroki Imaoka, Hiroyuki Fujikawa, Hiromi Yasuda, Takeshi Yokoe, Yoshiki Okita, Masaki Ohi and Yuji Toiyama

    Citation: World Journal of Surgical Oncology 2021 19:34

    Content type: Research

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  14. The role of surgical intervention as a treatment for pulmonary metastasis (PM) from hepatocellular carcinoma (HCC) has not been established. In this study, we investigated the clinical outcomes of pulmonary me...

    Authors: Han Pil Lee, Jae Kwang Yun, Hee Suk Jung, Duk Hwan Moon, Geun Dong Lee, Sehoon Choi, Yong-Hee Kim, Dong Kwan Kim, Seung Il Park and Hyeong Ryul Kim

    Citation: World Journal of Surgical Oncology 2021 19:33

    Content type: Research

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  15. Traumatic lymphatic leakage is a rare but potentially life-threatening complication. The purpose of this study was to introduce ultrasound-guided intranodal lymphangiography and embolisation techniques for pos...

    Authors: Xingwei Sun, Feng Zhou, Xuming Bai, Qiang Yuan, Mingqing Zhang, Liang Ma and Yong Jin

    Citation: World Journal of Surgical Oncology 2021 19:32

    Content type: Technical innovations

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  16. Cytoreductive surgery (CRS) combined with hyperthermic intraperitoneal chemotherapy (HIPEC) improves survival in selected patients with peritoneal metastasis (PM) from colorectal cancer (CRC). However, little ...

    Authors: Yasuyuki Kamada, Koya Hida, Haruaki Ishibashi, Shouzou Sako, Akiyoshi Mizumoto, Masumi Ichinose, Naveen Padmanabhan, Shinya Yoshida and Yutaka Yonemura

    Citation: World Journal of Surgical Oncology 2021 19:31

    Content type: Research

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  17. The identification of the homogeneous and heterogeneous risk factors for different types of metastases in colorectal cancer (CRC) may shed light on the aetiology and help individualize prophylactic treatment. ...

    Authors: Tianwen Luo, Yutong Wang, Xuefeng Shan, Ye Bai, Chun Huang, Guangcan Li and Hongmei Wang

    Citation: World Journal of Surgical Oncology 2021 19:30

    Content type: Research

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  18. This study aimed to evaluate the computed tomography (CT) features of solitary pulmonary nodule (SPN), which can be a non-invasive diagnostic tool to differentiate between primary lung cancer (LC) and solitary...

    Authors: Jong Eun Lee, Won Gi Jeong and Yun-Hyeon Kim

    Citation: World Journal of Surgical Oncology 2021 19:28

    Content type: Research

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  19. The aim of this study was to establish a regression equation model of serum bone metabolism markers. We analyzed the diagnostic value of bone metastases in lung cancer and provided laboratory evidence for the ...

    Authors: Zhongliang Zhu, Guangyu Yang, Zhenzhen Pang, Jiawei Liang, Weizhong Wang and Yonglie Zhou

    Citation: World Journal of Surgical Oncology 2021 19:27

    Content type: Research

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  20. Although the morbidity of gastric cancer has decreased, the incidence of adenocarcinoma of the esophagogastric junction (AEG) is increasing. Furthermore, no consensus exists on which surgical approach should b...

    Authors: Wei Pang, Gang Liu, Yan Zhang, Yun Huang, Xinpu Yuan, Zhanwei Zhao and Chaojun Zhang

    Citation: World Journal of Surgical Oncology 2021 19:26

    Content type: Research

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  21. An emerging prediction tool, the Controlling Nutritional Status (CONUT) score, has shown good assessment ability of postoperative outcomes in cancer patients. This study evaluated the role of the preoperative ...

    Authors: Yun Qian, Huaying Liu, Junhai Pan, Weihua Yu, Jiemin Lv, Jiafei Yan, Jiaqi Gao, Xianfa Wang, Xiaolong Ge and Wei Zhou

    Citation: World Journal of Surgical Oncology 2021 19:25

    Content type: Research

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  22. Multiple myeloma causes different types of renal injury. C3 glomerulonephritis (C3GN) is characterised by an abnormal deposition of complement C3 in the glomeruli due to abnormal activation of the alternative ...

    Authors: Junhui Xu, Xiaojuan Yu, Suxia Wang, Miao Yan, Mangju Wang, Jinping Ou, Lihong Wang, Huihui Liu and Xinan Cen

    Citation: World Journal of Surgical Oncology 2021 19:24

    Content type: Case report

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  23. The use of 3-dimensional (3D) endoscopic thyroidectomy (ET) has been increasing, but its feasibility and safety have not been well documented for thyroidectomy. Hence, to systematically investigate the compara...

    Authors: Zigao Huang, Haiquan Qin, Jiankun Liao, Linghou Meng, Yongjie Qin, Baojia Li, Hao Lai and Xianwei Mo

    Citation: World Journal of Surgical Oncology 2021 19:23

    Content type: Review

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  24. Peutz–Jeghers syndrome (PJS) is a very rare autosomal dominant genetic disorder characterized by hamartomatous polyps in the gastrointestinal tract and hyperpigmentation of the lips, hands, and feet. The hamar...

    Authors: Masaaki Yamamoto, Kazuya Iwamoto, Rei Suzuki, Yosuke Mukai, Tomohira Takeoka, Kei Asukai, Naoki Shinno, Hisashi Hara, Takashi Kanemura, Nozomu Nakai, Shinichiro Hasegawa, Keijiro Sugimura, Naotsugu Haraguchi, Junichi Nishimura, Hiroshi Wada, Hidenori Takahashi…

    Citation: World Journal of Surgical Oncology 2021 19:22

    Content type: Case report

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  25. Colorectal cancer patients undergoing surgical resection are at increased short-term risk of post-operative adverse events. However, specific predictors for long-term major adverse cardiac and cerebrovascular ...

    Authors: Chieh Yang Koo, Bee-Choo Tai, Dedrick Kok Hong Chan, Li Ling Tan, Ker Kan Tan and Chi-Hang Lee

    Citation: World Journal of Surgical Oncology 2021 19:21

    Content type: Research

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  26. As a common malignancy, gastric cancer (GC) remains an important threat to human’s health. The incidence of synchronous multiple gastric cancer (SMGC) has increased obviously with technical advances of endosco...

    Authors: Liang Chen, Chao Yue, Gang Li, Xuezhi Ming, Rongmin Gu, Xu Wen, Bin Zhou, Rui Peng, Wei Wei and Huanqiu Chen

    Citation: World Journal of Surgical Oncology 2021 19:20

    Content type: Research

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  27. Primary hyperparathyroidism is an endocrine pathology that affects calcium metabolism. Patients with primary hyperparathyroidism have high concentrations of serum calcium or high concentrations of parathyroid ...

    Authors: Alessandro Galani, Riccardo Morandi, Mira Dimko, Sarah Molfino, Carla Baronchelli, Silvia Lai, Federico Gheza, Carlo Cappelli and Claudio Casella

    Citation: World Journal of Surgical Oncology 2021 19:19

    Content type: Research

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  28. The aim of this study was to investigate the overall survival (OS) between proximal gastric cancer (PG) and distal gastric cancer (DG) patients after gastrectomy.

    Authors: Jiaming Xue, Huiliang Yang, Shanshan Huang, Tingting Zhou, Xiangwen Zhang and Guo Zu

    Citation: World Journal of Surgical Oncology 2021 19:17

    Content type: Review

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  29. Oral squamous cell carcinoma (OSCC) accounts for more than 90% of the oral carcinomas and has a high fatality rate. This study aimed to identify potentially diagnostic biomarkers of OSCC through integrated ana...

    Authors: Le Chen and Dong Wang

    Citation: World Journal of Surgical Oncology 2021 19:16

    Content type: Research

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  30. Pancreatic serous cystadenoma (SCA) is a benign, cystic lesion with an indolent growth pattern. Complications such as spontaneous hemorrhage or malignant transformation from SCA are extremely rare. Our case re...

    Authors: Da Eun Cha, Callie Horn and Michael Passeri

    Citation: World Journal of Surgical Oncology 2021 19:15

    Content type: Case report

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  31. Colorectal anastomosis using the double stapling technique (DST) has become a standard procedure. However, DST is difficult to perform in patients with anal stenosis because a circular stapler cannot be insert...

    Authors: Yosuke Tajima, Tsunekazu Hanai, Hidetoshi Katsuno, Koji Masumori, Yoshikazu Koide, Keigo Ashida, Hiroshi Matsuoka, Junichiro Hiro, Tomoyoshi Endo, Tadahiro Kamiya, Yongchol Chong, Kotaro Maeda and Ichiro Uyama

    Citation: World Journal of Surgical Oncology 2021 19:14

    Content type: Case report

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  32. Colon cancer is a worldwide leading cause of cancer-related mortality, and the prognosis of colon cancer is still needed to be improved. This study aimed to construct a prognostic model for predicting the prog...

    Authors: Zhengyu Fang, Sumei Xu, Yiwen Xie and Wenxi Yan

    Citation: World Journal of Surgical Oncology 2021 19:13

    Content type: Research

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  33. Venous thromboembolism (VTE) in ovarian cancer (OC) patients has been widely investigated, but our knowledge on the role of VTE in OC patients receiving chemotherapy is limited. The aim of our study was to inv...

    Authors: Lu Ye, Li Cai, Yonghui Fu, Debao Zhuang, Xiaoqing Hu and Youkun Jie

    Citation: World Journal of Surgical Oncology 2021 19:12

    Content type: Research

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  34. To investigate the prognostic factors of patients with pancreatic neuroendocrine tumor (pNETs) after surgical resection, and to analyze the value of enucleation for pNETs without distant metastasis that are we...

    Authors: Junzhang Chen, Yongyu Yang, Yuanhua Liu and Heping Kan

    Citation: World Journal of Surgical Oncology 2021 19:11

    Content type: Research

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  35. The differential diagnosis between primary adenocarcinoma of the pancreas head and distal cholangiocarcinoma remains a clinical challenge. Recent studies have shown important differences in terms of survival b...

    Authors: Edoardo Maria Muttillo, Antonio Ciardi, Raffaele Troiano, Paolina Saullo, Gabriele Masselli, Marianna Guida, Alessandra Tortora, Isabella Sperduti, Giulio Marinello, Piero Chirletti and Roberto Caronna

    Citation: World Journal of Surgical Oncology 2021 19:10

    Content type: Research

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  36. Very few studies have been conducted on the treatment strategy for enlarged paraaortic lymph nodes (PALNs) incidentally detected during surgery. The purpose of this study was to investigate the benefit of lymp...

    Authors: Jaram Lee, Hyeong-min Park, Soo Young Lee, Chang Hyun Kim and Hyeong Rok Kim

    Citation: World Journal of Surgical Oncology 2021 19:9

    Content type: Research

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  37. The long-term physiological consequences of SARS-CoV-2 (severe acute respiratory syndrome coronavirus) infection are not known. The ability of COVID-19 to cause chronic illness, sarcopenia, and physical decond...

    Authors: Patrick Casey, Yeng Ang and Javed Sultan

    Citation: World Journal of Surgical Oncology 2021 19:8

    Content type: Correspondence

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  38. Though better short-term outcomes were frequently reported, differences in specimen parameters and the rate of subsequent peritoneal recurrence between intracorporeal anastomosis (IA) and extracorporeal anasto...

    Authors: Chun-Kai Liao, Yih-Jong Chern, Yueh-Chen Lin, Yu-Jen Hsu, Jy-Ming Chiang, Wen-Sy Tsai, Pao-Shiu Hsieh, Hsin-Yuan Hung, Chien-Yuh Yeh and Jeng-Fu You

    Citation: World Journal of Surgical Oncology 2021 19:6

    Content type: Research

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  39. Methotrexate (MTX) is a frequently used drug in the treatment of rheumatoid arthritis (RA), but occurrences of lymphoproliferative disorders (LPD) have been reported in patients undergoing an MTX regimen. Almo...

    Authors: Masahiro Nomura, Ryusuke Sumiya, Hayato Ono, Takeshi Nagai, Keigo Kumazawa, Atsushi Shimizu, Daisuke Endo and Nobuyoshi Aoyanagi

    Citation: World Journal of Surgical Oncology 2021 19:4

    Content type: Case report

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  40. Gallbladder neuroendocrine neoplasm is a rare disease that is divided into neuroendocrine tumors (NETs) and neuroendocrine carcinomas (NECs). Clear cell NETs of the gallbladder are extremely rare. We report th...

    Authors: Ryusuke Sumiya, Atsushi Shimizu, Takeshi Nagai, Hayato Ono, Keigo Kumazawa, Daisuke Endo, Takashi Oide and Nobuyoshi Aoyanagi

    Citation: World Journal of Surgical Oncology 2021 19:3

    Content type: Case report

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  41. Heterotopic ossification (HO) is the formation of osseous tissue outside the skeleton. HO in malignant tumors of the digestive tract is extremely rare, as is ossification in metastatic lesions from HO-negative...

    Authors: Hideki Nagano, Tamotsu Togawa, Takeshi Watanabe, Kenji Ohnishi, Toshihisa Kimura, Atsushi Iida, Sakon Noriki, Yoshiaki Imamura, Yasunori Sato and Takanori Goi

    Citation: World Journal of Surgical Oncology 2021 19:2

    Content type: Case report

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  42. Minimally invasive liver surgery (MILS) in the treatment of colorectal liver metastases (CRLM) is increasing in incidence. The aim of this work was to present our experience by reporting short-term and long-te...

    Authors: Mirhasan Rahimli, Aristotelis Perrakis, Vera Schellerer, Andrew Gumbs, Eric Lorenz, Mareike Franz, Jörg Arend, Victor-Radu Negrini and Roland Siegfried Croner

    Citation: World Journal of Surgical Oncology 2020 18:333

    Content type: Research

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  43. This novel study compared the use of tumor necrosis factor (TNF)-alpha and melphalan-based isolated limb perfusion (TM-ILP) to the standard treatment of locally recurrent soft tissue extremity sarcoma. The aim...

    Authors: Farhad Farzaliyev, Alexander Touma, Georg Taeger, Hans-Ulrich Steinau, Jendrik Hardes, Arne Streitbürger and Lars Erik Podleska

    Citation: World Journal of Surgical Oncology 2020 18:332

    Content type: Research

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  44. This study aimed to evaluate the potential of induction chemotherapy as an indicator of the management of advanced hypopharyngeal carcinoma with cervical oesophageal invasion.

    Authors: Tian-Qiao Huang, Ru Wang, Ju-Gao Fang, Shi-Zhi He, Qi Zhong, Li-Zhen Hou, Hong-Zhi Ma, Xiao-Hong Chen, Xue-Jun Chen, Ping-Dong Li, Ling Feng, Qian Shi and Meng Lian

    Citation: World Journal of Surgical Oncology 2020 18:330

    Content type: Research

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  45. Endometriosis can potentially lead to the development of a malignant tumor. Most malignant tumors arising from the endometriosis originate from the ovarian endometrioma, whereas those arising from extragonadal...

    Authors: Yoshiaki Ota, Kuniaki Ota, Toshifumi Takahashi, Soichiro Suzki, Rikiya Sano, Ikuko Ota, Takuya Moriya and Mitsuru Shiota

    Citation: World Journal of Surgical Oncology 2020 18:329

    Content type: Case report

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