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  1. Content type: Research

    Inflammation-induced endothelial precursor cell recruitment and angiogenesis are thought to be associated with CXCL16-CXCR6 pair activity. This study’s main purpose was to determine plasma CXCL16 levels after ...

    Authors: H. M. C. Shantha Kumara, Erica Pettke, Abhinit Shah, Xiaohong Yan, Vesna Cekic, Melissa Alvarez Downing, Nipa Dilip Gandhi and Richard L. Whelan

    Citation: World Journal of Surgical Oncology 2018 16:132

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  2. Content type: Technical innovations

    In order to overcome the shortcomings of laparoscopic intersphincteric resection (Lap ISR), an alternative method of delivering intraoperative radiotherapy by Intrabeam X-rays radiotherapy system (XRS) is prop...

    Authors: Min Wang, Wangsheng Xue, Zeyun Zhao, Yongbo Li, Xinyu Wang, Tao Li, Yongbo Zou, Xiaowei Song, Mingwei Zhang, Tiejun Wang, Jianzheng Yang, Chunyu Wang and Shuang Wang

    Citation: World Journal of Surgical Oncology 2018 16:133

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  3. Content type: Research

    Recently, molecule-targeting and bone-modifying agents have improved the treatment outcomes of lung cancer-derived metastatic spine tumors. Therefore, the prognostic factors for such tumors were examined, and ...

    Authors: Hiroshi Uei and Yasuaki Tokuhashi

    Citation: World Journal of Surgical Oncology 2018 16:131

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  4. Content type: Research

    The incidence, site distribution, and mortality rates of patients with colorectal cancer differ according to gender. We investigated gene mutations in colorectal patients and wanted to examine gender-specific ...

    Authors: Yi-Jian Tsai, Sheng-Chieh Huang, Hung-Hsin Lin, Chun-Chi Lin, Yuan-Tzu Lan, Huann-Sheng Wang, Shung-Haur Yang, Jeng-Kai Jiang, Wei-Shone Chen, Tzu-chen Lin, Jen-Kou Lin and Shih-Ching Chang

    Citation: World Journal of Surgical Oncology 2018 16:128

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  5. Content type: Research

    Pakistan’s population is ethnically diverse with distinct ethnic groups inhabiting various parts of the country. Cancer statistics obtained from specific regions populated by distinct ethnic groups may vary co...

    Authors: Romana Idrees, Saira Fatima, Jamshid Abdul-Ghafar, Ahmad Raheem and Zubair Ahmad

    Citation: World Journal of Surgical Oncology 2018 16:129

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  6. Content type: Review

    Thyroid and breast cancer are two of the malignant diseases with highest incidence in females. Based on clinical experience, breast and thyroid cancer often occur metachronously or synchronously. Therefore, th...

    Authors: Liangbo Dong, Jun Lu, Bangbo Zhao, Weibin Wang and Yupei Zhao

    Citation: World Journal of Surgical Oncology 2018 16:130

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  7. Content type: Research

    HIF-1alpha and CAIX proteins are commonly expressed under hypoxic conditions, but other regulatory factors have been described as well. Pancreatic ductal adenocarcinoma (PDAC) is characterized by hypoxia and s...

    Authors: Joni Leppänen, Olli Helminen, Heikki Huhta, Joonas H. Kauppila, Joel Isohookana, Kirsi-Maria Haapasaari, Seppo Parkkila, Juha Saarnio, Petri P. Lehenkari and Tuomo J. Karttunen

    Citation: World Journal of Surgical Oncology 2018 16:127

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  8. Content type: Research

    This study aims to explore the feasibility of narrow-band imaging (NBI) applied for the diagnostic screening of a high-risk population of nasopharyngeal carcinoma (NPC) and increase the accuracy rate of nasoph...

    Authors: Yong-Feng Si, Zhuo-Xia Deng, Jing-Jin Weng, Jin-Yuan Si, Gui-Ping Lan, Ben-Jian Zhang, Yong Yang, Bo Huang, Xing Han, Ying Qin, Yang-Da Qin, Wei-Ming Xiong and Bing Li

    Citation: World Journal of Surgical Oncology 2018 16:126

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  9. Content type: Review

    Schwannomas of the colon and rectum are rare among gastrointestinal schwannomas. They are usually discovered incidentally as a submucosal mass on routine colonoscopy and diagnosed on pathologic examination of ...

    Authors: Ali Bohlok, Melody El Khoury, Anne Bormans, Maria Gomez Galdon, Michael Vouche, Issam El Nakadi, Vincent Donckier and Gabriel Liberale

    Citation: World Journal of Surgical Oncology 2018 16:125

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  10. Content type: Review

    Although numerous studies have shown that positive surgical margin (PSM) is linked to biochemical recurrence (BCR) in prostate cancer (PCa), the research results have been inconsistent. This study aimed to exp...

    Authors: Lijin Zhang, Bin Wu, Zhenlei Zha, Hu Zhao, Yuefang Jiang and Jun Yuan

    Citation: World Journal of Surgical Oncology 2018 16:124

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  11. Content type: Research

    Docetaxel, cisplatin, and 5-fluorouracil (DCF) therapy can cause severe adverse events, including neutropenia and febrile neutropenia. The feasibility of DCF therapy is a concern, particularly for elderly pati...

    Authors: Yuji Akiyama, Akira Sasaki, Fumitaka Endo, Haruka Nikai, Satoshi Amano, Akira Umemura, Shigeaki Baba, Takehiro Chiba, Toshimoto Kimura, Takeshi Takahara, Hiroyuki Nitta, Koki Otsuka, Masaru Mizuno, Yusuke Kimura, Keisuke Koeda and Takeshi Iwaya

    Citation: World Journal of Surgical Oncology 2018 16:122

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  12. Content type: Case report

    The ethical implications of the utilization of kidneys with solid renal masses (SRMs) in transplantation are the subject of lively debate in the transplantation community and beyond. One of such implications i...

    Authors: Duilio Pagano, Fabrizio di Francesco, Liotta Rosa, Chibueze A. Nwaiwu, Sergio Li Petri and Salvatore Gruttadauria

    Citation: World Journal of Surgical Oncology 2018 16:123

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  13. Content type: Review

    Inflammatory bowel disease (IBD), which includes ulcerative colitis (UC) and Crohn’s disease (CD), is a chronic, idiopathic, repeated inflammatory disease. Colorectal cancer (CRC) that develops in patients wit...

    Authors: Hitoshi Kameyama, Masayuki Nagahashi, Yoshifumi Shimada, Yosuke Tajima, Hiroshi Ichikawa, Masato Nakano, Jun Sakata, Takashi Kobayashi, Sumana Narayanan, Kazuaki Takabe and Toshifumi Wakai

    Citation: World Journal of Surgical Oncology 2018 16:121

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  14. Content type: Technical innovations

    Our article describes our experience with using a frontal axial pattern flap combined with hard palate mucosa transplant to reconstruct midfacial defects after the excision of huge basal cell carcinoma.

    Authors: Junliang Wu, Yong Qing, Ying Cen and Junjie Chen

    Citation: World Journal of Surgical Oncology 2018 16:120

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  15. Content type: Research

    The treatment strategies for colorectal cancer located in the right side of the colon have changed dramatically during the last decade. Due to the introduction of complete mesocolic excision (CME) with central...

    Authors: Jörg O. W. Pelz, Johanna Wagner, Sven Lichthardt, Johannes Baur, Caroline Kastner, Niels Matthes, Christoph-Thomas Germer and Armin Wiegering

    Citation: World Journal of Surgical Oncology 2018 16:117

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  16. Content type: Case Report

    Splenosis is the heterotopic autotransplantation and implantation of splenic tissue after splenic trauma or splenectomy. Considering that splenosis often occurs in the mesentery, omentum, and peritoneum, intra...

    Authors: Zefeng Xuan, Jian Chen, Penghong Song, Yehui Du, Lijun Wang, Dalong Wan and Shusen Zheng

    Citation: World Journal of Surgical Oncology 2018 16:119

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  17. Content type: Research

    In this study, we intend to determine the immunohistochemical expression of EGFR in cases of head and neck squamous cell carcinoma and its association with prognostic clinico-pathologic features.

    Authors: Atif Ali Hashmi, Zubaida Fida Hussain, Saher Aijaz, Muhammad Irfan, Erum Yousuf Khan, Samreen Naz, Naveen Faridi, Amir Khan and Muhammad Muzzammil Edhi

    Citation: World Journal of Surgical Oncology 2018 16:118

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  18. Content type: Research

    To stage axillary lymph nodes in women with early-stage breast cancer, sentinel lymph node biopsy (SLNB), rather than axillary lymph node dissection (ALND), has been employed. Moreover, different tracer method...

    Authors: Liulu Zhang, Yijie Huang, Ciqiu Yang, Teng Zhu, Yufeng Lin, Hongfei Gao, Mei Yang, Minyi Cheng and Kun Wang

    Citation: World Journal of Surgical Oncology 2018 16:112

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  19. Content type: Case report

    A tumor composed exclusively or predominantly of human melanin black 45 (HMB45)-positive epithelioid cells is called a perivascular epithelioid cell tumor (PEComa). We report a very rare case of a PEComa of th...

    Authors: Koichi Okamoto, Yuka Okada, Kohei Ohno, Takahiro Yagi, Mitsuo Tsukamoto, Takuya Akahane, Ryu Shimada, Tamuro Hayama, Takeshi Tsuchiya, Keijiro Nozawa, Keiji Matsuda, Tsuyoshi Ishida, Fukuo Kondo and Yojiro Hashiguchi

    Citation: World Journal of Surgical Oncology 2018 16:113

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  20. Content type: Case report

    Local excision (LE) is currently one of the most effective methods used in cases of large benign polyps, not suitable for endoscopic treatment, or early-stage neoplasms. LE is also alternative to anterior rect...

    Authors: Maria Rita Cozzi, Andrea Lauretta, Roberto Vettori and Agostino Steffan

    Citation: World Journal of Surgical Oncology 2018 16:115

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  21. Content type: Research

    This study was carried out to discover the underlying role that HOXA11 plays in lung squamous cancer (LUSC) and uncover the potential corresponding molecular mechanisms and functions of HOXA11-related genes.

    Authors: Rui Zhang, Tong-tong Zhang, Gao-qiang Zhai, Xian-yu Guo, Yuan Qin, Ting-qing Gan, Yu Zhang, Gang Chen, Wei-jia Mo and Zhen-bo Feng

    Citation: World Journal of Surgical Oncology 2018 16:109

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  22. Content type: Correspondence

    The study performed by Zhou et al. (World J Surg Oncol 15:104, 2017) titled “Clinical and prognostic significance of HIF-1α overexpression in oral squamous cell carcinoma: a meta-analysis” attempts to highligh...

    Authors: Rama Jayaraj, Chellan Kumarasamy, Madhav Madurantakam Royam, Arikketh Devi and Siddharta Baxi

    Citation: World Journal of Surgical Oncology 2018 16:111

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  23. Content type: Research

    The response to temozolomide (TMZ) treatment in small-cell lung cancer (SCLC) correlated with O(6)-methylguanine -DNA methyltransferase (MGMT) promoter methylation. 1p/19q co-deletion within oligodendroglioma ...

    Authors: Lei Lei, Zhiming Jiang, Gu Zhang, Qiaoyuan Cheng and Hongyang Lu

    Citation: World Journal of Surgical Oncology 2018 16:110

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  24. Content type: Research

    Despite recent advances in diagnosis and treatment, prostate cancer (PCa) remains the leading cause of cancer-related deaths in men. Current treatments offered in the clinics are often toxic and have severe si...

    Authors: Ashley B. Ward, Hina Mir, Neeraj Kapur, Dominique N. Gales, Patrick P. Carriere and Shailesh Singh

    Citation: World Journal of Surgical Oncology 2018 16:108

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  25. Content type: Research

    To assess the oncologic outcomes of radiation therapy (RT) combined with maximal androgen blockade (MAB) and prostate-specific antigen (PSA) kinetics in patients with localized, high-risk prostate carcinoma (P...

    Authors: Yong Luo, Mingchuan Li, Hengzhi Qi, Jiahui Zhao, Yili Han, Yunhua Lin, Zhu Hou and Yongguang Jiang

    Citation: World Journal of Surgical Oncology 2018 16:107

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  26. Content type: Research

    Some patients experience a non-traumatic pain in the tibial diaphysis similar to that in the clinical and radiological findings of a tumor, an infection or a stress fracture and cannot be definitively diagnose...

    Authors: Yavuz Arikan, Yasar Mahsut Dincel, Baris Ozkul, Rasit Ozcafer, Akay Kirat and Devrim Ozer

    Citation: World Journal of Surgical Oncology 2018 16:106

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  27. Content type: Research

    Neoadjuvant chemoradiotherapy (NACRT) has now become the standard treatment for locally advanced rectal cancer (LARC). NACRT has decreased local relapse (LR) rate in patients with LARC; however, distant relaps...

    Authors: Takashi Okuyama, Shinichi Sameshima, Emiko Takeshita, Ryuji Yoshioka, Yukinori Yamagata, Yuko Ono, Nobumi Tagaya, Tamaki Noie and Masatoshi Oya

    Citation: World Journal of Surgical Oncology 2018 16:105

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  28. Content type: Research

    Chemoradiotherapy has a dominant role in therapy for head and neck cancers. However, impressive results are often disturbed by adverse events such as dysphagia, xerostomia, and functional speech and hearing lo...

    Authors: Karl Reinhard Aigner, Sabine Gailhofer and Kornelia Aigner

    Citation: World Journal of Surgical Oncology 2018 16:104

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  29. Content type: Technical innovations

    Efficient hemostatic techniques are essential in laparoscopic surgery for ideal intraoperative and postoperative results. A variety of advanced devices are available for the sealing of major vascular structure...

    Authors: Michele Grieco, Daniela Apa, Domenico Spoletini, Emanuela Grattarola and Massimo Carlini

    Citation: World Journal of Surgical Oncology 2018 16:101

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  30. Content type: Research

    Malignant adnexal tumors of the skin (MATS) are rare. We aimed to measure the survival of patients with MATS and identify predictors of improved survival.

    Authors: Tolutope Oyasiji, Wei Tan, John Kane III, Joseph Skitzki, Valerie Francescutti, Kilian Salerno and Nikhil I. Khushalani

    Citation: World Journal of Surgical Oncology 2018 16:99

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  31. Content type: Research

    The preoperative selection of patients with lung cancer recurrence remains a major clinical challenge. Several aspects of this kind of surgery are still insufficiently evidence-based, with only a few series wi...

    Authors: Dragan Subotic, Laureano Molins, Ivan Soldatovic, Dejan Moskovljevic, Lucia Collado and Jorge Hernández

    Citation: World Journal of Surgical Oncology 2018 16:98

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  32. Content type: Research

    Short- and long-term health-related quality of life (HRQL) was severely affected after surgery. This study aimed to assess the direction and duration of HRQL from 3- to 24-month follow-ups after minimally inva...

    Authors: Yong Zhang, Xiaomei Yang, Donghong Geng, Yingfei Duan and Junke Fu

    Citation: World Journal of Surgical Oncology 2018 16:97

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  33. Content type: Research

    Sentinel lymph node dissection (SLND) may reduce morbidity in patients with endometrial cancer. The objective of this study is to estimate how many systematic lymph node dissections (LND) can be spared with an...

    Authors: Sarah Brugger, Moritz Hamann, Marc Mosner, Michaela Beer, Michael Braun and Martin Pölcher

    Citation: World Journal of Surgical Oncology 2018 16:95

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  34. Content type: Review

    Gastrointestinal cancers are among the most recognised oncological diseases in well-developed countries. Tumours located in the digestive tract may cause the fast occurrence of malnutrition.

    Authors: Michal Jankowski, Manuela Las-Jankowska, Massaoud Sousak and Wojciech Zegarski

    Citation: World Journal of Surgical Oncology 2018 16:94

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  35. Content type: Research

    We introduced a palliative joint-preserving surgery using proximal self-locking screws of intramedullary (IM) nail and percutaneous cementoplasty (PC) in patients with proximal humeral metastases, including th...

    Authors: Jong Woong Park, Yong-il Kim, Hyun Guy Kang, June Hyuk Kim and Han Soo Kim

    Citation: World Journal of Surgical Oncology 2018 16:93

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  36. Content type: Case report

    Inguinal hernia is one of the most common benign pathologies that primarily affects men. Primary gastrointestinal non-Hodgkin’s lymphoma (PGI NHL) is the most common type of extranodal lymphoma. This study rep...

    Authors: Michele Teodoro, Maurizio Mannino, Marco Vitale, Edoardo Mattone, Valentina Palumbo, Filippo Fraggetta, Adriana Toro and Isidoro Di Carlo

    Citation: World Journal of Surgical Oncology 2018 16:91

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  37. Content type: Research

    The goal of the study was to investigate the current clinical practices among oncologic surgeons regarding cytoreductive surgery (CRS) with intraoperative hyperthermic intraperitoneal chemotherapy (HIPEC).

    Authors: Heon Jong Yoo, Jenny J. Hong, Young Bok Ko, Mina Lee, Youjin Kim, Hye Young Han, Yong Jung Song, Myong Cheol Lim and Sang-Yoon Park

    Citation: World Journal of Surgical Oncology 2018 16:92

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  38. Content type: Research

    The aim of our study was to evaluate the clinical safety and value of ethanol surgical field infiltration (ESFI), combined with distilled water peritoneal lavage (DWPL), after hepatectomy in patients with hepa...

    Authors: Jian Sun, Yue Zhu, Yao-rong Peng, Wen-bin Li, He-yun Zhang, Zhen-yu Zhou, Lin Wang, An-de Ma and Jie Wang

    Citation: World Journal of Surgical Oncology 2018 16:86

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  39. Content type: Research

    Patient selection for cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) is critically important to optimizing outcomes. There is currently no literature regarding the safety of ...

    Authors: Anna Weiss, Erin P. Ward, Joel M. Baumgartner, Andrew M. Lowy and Kaitlyn J. Kelly

    Citation: World Journal of Surgical Oncology 2018 16:87

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  40. Content type: Research

    To evaluate the incidence of incisional hernia (IH) after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS + HIPEC) and its impact on health-related quality of life (HRQoL).

    Authors: Sissel Ravn, Henriette Vind Thaysen, Sanne Harsløf, Mette Møller Sørensen and Lene Hjerrild Iversen

    Citation: World Journal of Surgical Oncology 2018 16:85

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  41. Content type: Research

    Steep pulse therapy can irreversible electrically brackdown of tumor membrance and cause cell death. In previous studies, we investigated the effect of steep pulsed electroporation on the killing of large cell...

    Authors: Zuoqing Song, Xiaohong Xu, Minghui Liu, Jinghao Liu, Jun Chen, Chengxiang Li, Chenguo Yao and Qinghua Zhou

    Citation: World Journal of Surgical Oncology 2018 16:84

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