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  1. Immune checkpoint inhibitors (ICIs) have dramatically prolonged survival in non-small cell lung cancer (NSCLC) patients, but little research had focused on its impact on quality of life (QoL). The purpose of o...

    Authors: Wei Liu, Qian Zhang, Tiantian Zhang, Li Li and Chunhua Xu
    Citation: World Journal of Surgical Oncology 2022 20:333
  2. Intramural metastasis distant from the primary tumor is rare in colorectal cancer. Here, we present a notably rare and probably the first case of asynchronous intramural recurrence in the rectum after curative...

    Authors: Yusuke Asada, Katsuya Chinen, Ken Yamataka, Jo Tokuyama, Naoto Kurihara and Shuhei Iida
    Citation: World Journal of Surgical Oncology 2022 20:332
  3. Mitochondria play critical roles in cellular physiological activity as cellular organelles. Under extracellular stimulation, mitochondria undergo constant fusion and fission to meet different cellular demands....

    Authors: Jixiang Xing, Luyao Qi, Xiaofei Liu, Guangxi Shi, Xiaohui Sun and Yi Yang
    Citation: World Journal of Surgical Oncology 2022 20:331
  4. The aim of this study was to develop comprehensive and effective nomograms for predicting overall survival (OS) and cancer-specific survival (CSS) rates in patients with colorectal mucinous adenocarcinoma (CRMA).

    Authors: Pengchao Wang, Qingyu Song, Ming Lu, Qingcheng Xia, Zijun Wang, Qinghong Zhao and Xiang Ma
    Citation: World Journal of Surgical Oncology 2022 20:330
  5. Circular RNA (circRNA) has been proved to be an important molecular target for cancer treatment. However, the function and molecular mechanism of circ_0000808 in non-small cell lung cancer (NSCLC) are still un...

    Authors: Yong Cai, Zhiyi Dong and Jiying Wang
    Citation: World Journal of Surgical Oncology 2022 20:329
  6. Hepatocellular carcinoma (HCC) is the third most common cause of cancer death worldwide, with an overall 5-year survival rate of less than 18%, which may be related to tumor microvascular invasion (MVI). This ...

    Authors: Yuling Xiong, Peng Cao, Xiaohua Lei, Weiping Tang, Chengming Ding, Shuo Qi and Guodong Chen
    Citation: World Journal of Surgical Oncology 2022 20:328
  7. The data in the real-world setting on breast pathologic complete response (pCR) after neoadjuvant chemotherapy (NAC) for hormone receptor–positive, human epidermal growth factor receptor-2-negative (HR+, HER2−...

    Authors: Dandan Guan, Qiu Jie, Yihao Wu, Yuhao Xu, Weimin Hong and Xuli Meng
    Citation: World Journal of Surgical Oncology 2022 20:326
  8. Accurate tumor staging is the cornerstone of tumor treatment. Current tumor staging system for gastric cancer (GC) is based on regional positive lymph nodes while ignoring the total number of examined lymph no...

    Authors: Yuhua Liu, Hao Cui, Xinxin Xu and Wenquan Liang
    Citation: World Journal of Surgical Oncology 2022 20:325
  9. Transurethral resection of the bladder tumor (TURBT) is one of the most established urological procedures for the treatment of the primary non-muscle-invasive bladder cancer (NMIBC). The aim of the study is to...

    Authors: Tianci Mao, Hongyi Zhang, Jie Cui, Zhiguang Zhao, Dian Jiao and Wei Zhang
    Citation: World Journal of Surgical Oncology 2022 20:324
  10. Multi-detector computed tomography (MDCT) and serum tumor markers are commonly used in the diagnosis of pancreatic cancer (PC). In this article, we focused on the evaluation of the clinical value of MDCT combi...

    Authors: Jianli Su, Yunfeng Wang, Hua Shao, Xinting You and Shuying Li
    Citation: World Journal of Surgical Oncology 2022 20:323
  11. Soft tissue sarcoma (STS) is a malignant tumor of highly heterogeneous mesenchymal origin. STS has a biological pattern and clinical transformation with localized invasive growth and is susceptible to hematoge...

    Authors: Xiao-Yao Feng, Jing Li, Ao-Mei Li, Sheng-Hua Jing, Xi-Xu Zhu and Zhen Wang
    Citation: World Journal of Surgical Oncology 2022 20:322
  12. Tumor-specific neoantigens are ideal targets for cancer immunotherapy. As research findings have proved, neoantigen-specific T cell activity is immunotherapy’s most important determinant.

    Authors: Zahra Shokati Eshkiki, Shahram Agah, Seidamir Pasha Tabaeian, Meghdad Sedaghat, Fatemeh Dana, Atefeh Talebi and Abolfazl Akbari
    Citation: World Journal of Surgical Oncology 2022 20:321
  13. The systemic immune-inflammation index (SII) is an inflammatory parameter calculated as platelet count × neutrophil count/lymphocyte count in the peripheral blood. In recent years, the prognostic role of the S...

    Authors: Buwen Zhang and Weiyun Yao
    Citation: World Journal of Surgical Oncology 2022 20:320
  14. This study aimed to analyze the safety of circular lateral anastomosis and cross-lateral anastomosis in laparoscopic radical resection of right-sided colon cancer.

    Authors: Xiaoming Wang, Hongyan Ni, Wangqiang Jia, Sen Wang, Yangyang Zhang, Peng Zhao and Long Yuan
    Citation: World Journal of Surgical Oncology 2022 20:318
  15. Desmoid-type fibromatosis (DTF) is a rare benign lesion that usually arises from the abdominal wall or extremities and rarely from the mesentery or intrabdominal organs. Malignant peritoneal mesothelioma is al...

    Authors: Stephanie N. Gregory, Audra A. Satterwhite, H. Richard Alexander and Andrew M. Blakely
    Citation: World Journal of Surgical Oncology 2022 20:317
  16. PDZ-binding kinase/T-lymphokine-activated killer cell-derived protein kinase (PBK/TOPK) is a potential prognostic indicator for patients with breast cancer. The objective of the present study was to explore th...

    Authors: Liang Qiao, Jinling Ba, Jiping Xie, Ruiping Zhu, Yi Wan, Min Zhang, Zeyu Jin, Zicheng Guo, Jiaxuan Yu, Sijing Chen and Yongqiang Yao
    Citation: World Journal of Surgical Oncology 2022 20:316
  17. Studies on surgical outcomes after robotic surgery are increasing; however, long-term oncological results of studies comparing robotic-assisted distal gastrectomy (RADG) versus laparoscopic-assisted distal gas...

    Authors: Gengmei Gao, Hualin Liao, Qunguang Jiang, Dongning Liu and Taiyuan Li
    Citation: World Journal of Surgical Oncology 2022 20:315
  18. There are currently no scoring-type predictive models using only easily available pre- and intraoperative data developed for assessment of the risk of advanced axillary lymph node metastasis (ALNM) in patients...

    Authors: Takeshi Murata, Chikashi Watase, Sho Shiino, Arisa Kurita, Ayumi Ogawa, Kenjiro Jimbo, Eriko Iwamoto, Masayuki Yoshida, Shin Takayama and Akihiko Suto
    Citation: World Journal of Surgical Oncology 2022 20:314
  19. Anastomotic blood supply is vital to anastomotic healing. The aim of this study was to demonstrate the effect of the left colic artery (LCA) on blood supply in the anastomotic area, explore the relationship be...

    Authors: Bo Li, Jianan Wang, Shaohui Yang, Jie Shen, Qi Li, Qiqi Zhu and Wei Cui
    Citation: World Journal of Surgical Oncology 2022 20:313
  20. The purpose of this study was to describe a surgical technique of bone resection with periosteal preservation and reconstruction in patients with high-grade bone malignant tumors and to determine its effect on...

    Authors: Mahmoud Smida, Ameni Ammar, Faten Fedhila, Wiem Douira and Samia Sassi
    Citation: World Journal of Surgical Oncology 2022 20:312
  21. Additional surgery is recommended after non-curative endoscopic submucosal dissection for early gastric cancer. However, it is not easy to recommend for tumors located in the upper third of the stomach, becaus...

    Authors: Sin Hye Park, Hong Man Yoon, Keun Won Ryu, Young-Woo Kim, Myeong-Cherl Kook and Bang Wool Eom
    Citation: World Journal of Surgical Oncology 2022 20:311
  22. Intraductal papillary mucinous neoplasms (IPMNs) are characterized by their abundant mucin production and malignant potential. IPMNs of the pancreas are mainly managed according to their radiographic indicatio...

    Authors: Yunzhen Qian, Yitao Gong, Guopei Luo, Yu Liu, Ruijie Wang, Xuan Zou, Shengming Deng, Xuan Lin, Yusheng Chen, Xu Wang, Xianjun Yu, He Cheng and Chen Liu
    Citation: World Journal of Surgical Oncology 2022 20:310
  23. Preoperative absolute lymphocyte count (LC) and fibrinogen (FIB) are useful prognostic indicators in colorectal cancer (CRC). However, the prognostic value of the LC to FIB ratio (LFR) has never been addressed.

    Authors: Xiang Huang, Yu Huan, Long Liu, Qianwen Ye, Jian Guo and Bing Yan
    Citation: World Journal of Surgical Oncology 2022 20:309
  24. Pylorus-preserving gastrectomy (PPG) is a function-preserving surgery for the treatment of early gastric cancer (EGC) in the middle third of the stomach. According to the literature reports, PPG decreases the ...

    Authors: Sen Hou, Fan Liu, Zhidong Gao and Yingjiang Ye
    Citation: World Journal of Surgical Oncology 2022 20:308
  25. This article is a response to “comment on ‘Pooled analysis of Xpert bladder cancer based on the 5 mRNAs for rapid diagnosis of bladder carcinoma’” by Gopal Sharma. With this comment, author highlighted the str...

    Authors: Yu-Fei Xie, Ye-Ling Liu and Xu-Guang Guo
    Citation: World Journal of Surgical Oncology 2022 20:306
  26. As transanal total mesorectal excision (taTME) is performed worldwide, the optimization of existing training and guidance programs to enhance new taTME learners’ competence in performing this procedure is warr...

    Authors: Fengming Xu, Yiqiao Zhang, Jiafu Yan, Bowen Xu, Guocong Wu, Zhengyang Yang, Liting Sun, Xiao Zhang, Hongwei Yao and Zhongtao Zhang
    Citation: World Journal of Surgical Oncology 2022 20:305
  27. Tumor deposits (TDs) have been identified as an independent prognostic factor in gastric cancer (GC). However, the associated clinicopathological factors and how to simply and reasonably incorporate TD into th...

    Authors: Menglong Zhou, Wang Yang, Wei Zou, Jianing Yang, Changming Zhou, Zhiyuan Zhang, Yaqi Wang, Jing Zhang, Yan Wang, Guichao Li, Zhen Zhang and Fan Xia
    Citation: World Journal of Surgical Oncology 2022 20:304
  28. Increasing evidences have revealed the tumor immune microenvironment not only has vital impacts on the origin, progression, and metastasis of tumors significantly but also influences the response to immunother...

    Authors: Dong Dong, Wei Wang, Heng Wang, Liang Chen and Tianyi Liu
    Citation: World Journal of Surgical Oncology 2022 20:303
  29. India encountered two waves of COVID-19 pandemic with variability in its characteristics and severity. Concerns were raised over the safety of treatment, and higher morbidity was predicted for oncological surg...

    Authors: Kishan Soni, J. F. Neville, Roli Purwar, Tarun Kumar, Ghanshyam Yadav, Nimisha Verma and Manoj Pandey
    Citation: World Journal of Surgical Oncology 2022 20:302
  30. Upregulation of Stathmin 1 (STMN1), a cytoplasmic phosphoprotein that controls the dynamics of cellular microtubules, is linked to malignant behavior and poor prognosis in a range of malignancies. However, lit...

    Authors: En-di Zhang, Chenxuan Li, Yuan Fang, Na Li, Zhongyun Xiao, Chuhong Chen, Benkai Wei, Hangping Wang, Jincheng Xie, Yinglei Miao, Zhong Zeng and Hanfei Huang
    Citation: World Journal of Surgical Oncology 2022 20:301
  31. National lead time goals have been implemented across Sweden to standardize and improve cancer patient care. However, the prognostic impact of lead times has not yet been studied in patients with colorectal ca...

    Authors: Ylva Jansson, Wilhelm Graf and Lana Ghanipour
    Citation: World Journal of Surgical Oncology 2022 20:300
  32. Primary liver cancer is the second-most commonly occurring cancer and has resulted in numerous deaths worldwide. Hepatic resection is of two main types, i.e., anatomic resection (AR) and non-anatomic resection...

    Authors: Xiao-ming Dai, Zhi-qiang Xiang, Qian Wang, Hua-jian Li and Zhu Zhu
    Citation: World Journal of Surgical Oncology 2022 20:299
  33. Hepatocellular carcinoma (HCC) remains a major health problem despite the emergence of several preventive and therapeutic modalities. HCC has heterogeneous and wide morpho-molecular patterns, resulting in uniq...

    Authors: Dina Sweed, Enas Sweed, Inas Moaz, Asmaa Mosbeh, Yahya Fayed, Sara Mohamed Abd Elhamed, Eman Sweed, Mahmoud Macshut, Shimaa Abdelsattar, Shimaa Kilany, Sara A. Saied, Reda Badr, Mahmoud S. Abdallah and Nermine Ehsan
    Citation: World Journal of Surgical Oncology 2022 20:298
  34. Epilepsy is one of the most common glioma complications, and the two may be connected in more ways than we understand. We aimed to investigate the clinical features of glioma-associated epilepsy and explore th...

    Authors: Honglin Ge, Guangfu Di, Zheng Yan, Dongming Liu, Yong Liu, Kun Song, Kun Yang, Xinhua Hu, Zijuan Jiang, Xiao Hu, Lei Tian, Chaoyong Xiao, Yuanjie Zou, Hongyi Liu and Jiu Chen
    Citation: World Journal of Surgical Oncology 2022 20:297
  35. The safe distance between the intraoperative resection line and the visible margin of the distal rectal tumor after preoperative radiotherapy is unclear. We aimed to investigate the furthest tumor intramural s...

    Authors: Ge Sun, Xiaolong Ye, Kuo Zheng, Hang Zhang, Paul Broens, Monika Trzpis, Zheng Lou, Xianhua Gao, Lianjie Liu, Liqiang Hao, Edgar Furnee, Chenguang Bai and Wei Zhang
    Citation: World Journal of Surgical Oncology 2022 20:296
  36. Increasing studies have indicated that noncoding RNA (ncRNA)-mediated competing endogenous RNA (ceRNA) network serves as a significant role in cancer progression, but the underlying regulatory mechanisms of wh...

    Authors: Jianxin Li, Ting Han, Xin Wang, Yinchun Wang, Xuan Chen, Wangsheng Chen and Qingqiang Yang
    Citation: World Journal of Surgical Oncology 2022 20:295
  37. Lymph or chyle leak (LL/CL) is severe complications after lateral cervical lymph node dissection (LLND), mainly due to iatrogenic injury of the lymphatic duct. Efficient and well-operated methods to reduce pos...

    Authors: Ming-Liang Zhang, Lou-Ming Guo, Peng-Cheng Li, Jing-Kang Zhang and Chen-Xu Guo
    Citation: World Journal of Surgical Oncology 2022 20:294
  38. An investigation of the effects of different types of the inferior mesenteric artery (IMA) on laparoscopic left colic artery (LCA) radical resection of rectal cancer was conducted.

    Authors: Jinghao Chen, Meirong Wang, Yuhao Chen, Suying Chen, Jing Xiao, Xiaole Fan, Jushun Yang and Bosheng He
    Citation: World Journal of Surgical Oncology 2022 20:292
  39. SMAD4 is a key mediator of TGFβ signaling and one of the mutated genes in extrahepatic bile duct cancer (eBDC). It has been also reported that SMAD4 has dual functions, in carcinogenesis via silencing and in t...

    Authors: Hirotoshi Takayama, Shogo Kobayashi, Kunihito Gotoh, Kazuki Sasaki, Yoshifumi Iwagami, Daisaku Yamada, Yoshito Tomimaru, Hirofumi Akita, Tadafumi Asaoka, Takehiro Noda, Hiroshi Wada, Hidenori Takahashi, Masahiro Tanemura, Yuichiro Doki and Hidetoshi Eguchi
    Citation: World Journal of Surgical Oncology 2022 20:291
  40. Currently, high or low ligation of the inferior mesenteric artery (IMA) is a controversial issue in laparoscopic radical surgery for colorectal cancer. High or low ligation of the IMA has both advantages and d...

    Authors: Shun Zeng, Wenhao Wu, Xianbin Zhang, Tong Qiu and Peng Gong
    Citation: World Journal of Surgical Oncology 2022 20:290
  41. Alpha‑fetoprotein-producing gastric cancer (AFPGC) is a rare type of gastric cancer with a high rate of metastasis and poor prognosis. Despite substantial progress in the treatment of many solid tumors, there ...

    Authors: Jinyu Xiang, Wenjing Gong, CongCong Wang, Ping Sun and Aina Liu
    Citation: World Journal of Surgical Oncology 2022 20:289
  42. Although syringoma is a common benign tumour of the sudoriferous gland, there is also an extremely rare malignant form known as syringoid eccrine carcinoma (SEC). SEC usually exhibits slow growth with deep inv...

    Authors: Zdeněk Dvořák, Richard Pink, Petr Heinz, Jaroslav Michálek and Petr Krsička
    Citation: World Journal of Surgical Oncology 2022 20:288
  43. Visceral hemangiomatosis is a benign tumor (rarer than hemangioma) that has not been reported to occur in the pancreas, duodenum, or choledoch. It can be easily confused with other pancreatic tumors or choledo...

    Authors: Daguang Tian, Hong Zhu and Xiaoping Wei
    Citation: World Journal of Surgical Oncology 2022 20:286
  44. To provide a rare case of local recurrent Paget’s disease after nipple-sparing mastectomy (NSM) with immediate breast reconstruction with 10 years of disease-free survival and to analyze the clinical and patho...

    Authors: Qian Pu, Qianqian Zhao and Dezong Gao
    Citation: World Journal of Surgical Oncology 2022 20:285
  45. To summarize our clinical experience of cryoablation in renal cell carcinoma (RCC) of Chinese population and to evaluate the long-term outcomes of laparoendoscopic single-site (LESS) cryoablation (LCA) as well...

    Authors: Shangqing Song, Qing Yang, Chengyuan Gu, Guopeng Yu, Bao Hua, Xin Gu, Linhui Wang, Zhong Wang, Guohai Shi and Bin Xu
    Citation: World Journal of Surgical Oncology 2022 20:284

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