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  1. Response evaluation following neoadjuvant chemotherapy (NAC) in gastric cancer is debated. The aim of this study was to investigate the value of UICC-downstaging as mode of response evaluation following a MAGIC-s...

    Authors: Alina Desiree Sandø, Reidun Fougner, Jon Erik Grønbech and Erling Audun Bringeland

    Citation: World Journal of Surgical Oncology 2021 19:212

    Content type: Research

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  2. The aim of this study was to evaluate the predictive factors of central lymph node metastasis (CLNM) and BRAFV600E mutation in Chinese patients with papillary thyroid carcinoma (PTC).

    Authors: Sheng Li Zhou, Yan Ping Guo, Lei Zhang, Tao Deng, Zi Guang Xu, Chao Ding, Wen Cong Sun, Yue Wu Zhao and Ling Fei Kong

    Citation: World Journal of Surgical Oncology 2021 19:211

    Content type: Research

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  3. This meta-analysis was implemented to evaluate the association between hypoxia-inducible factor-1α (HIF-1α) C1772T/G1790A polymorphisms and susceptibility to head and neck cancer (HNC).

    Authors: Ting Wu, Zhong-ti Zhang, Lin Li, Ru-yue Liu and Bao-ting Bei

    Citation: World Journal of Surgical Oncology 2021 19:210

    Content type: Review

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  4. This study aimed to evaluate the clinical outcomes for patients with stage IB2/IIA2 cervical squamous cell carcinoma treated with neoadjuvant chemotherapy combined with radical surgery.

    Authors: Huang Jing, Wu Xiuhong, Yu Ying, Liao Zhenrong, Cheng Xiyun, Luo Deping, Shen Changmei, Wang Qi, Peng Tao and Pan Yiyun

    Citation: World Journal of Surgical Oncology 2021 19:209

    Content type: Research

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  5. An abrupt increase of thyroid cancer has been witnessed paralleling the supplemented iodine intake in formerly iodine-deficient countries. And increased iodine intake has been linked to the rising incidence ra...

    Authors: Ziyang Zeng, Kang Li, Xianze Wang, Siwen Ouyang, Zimu Zhang, Zhen Liu, Juan Sun, Xin Ye, Weiming Kang and Jianchun Yu

    Citation: World Journal of Surgical Oncology 2021 19:208

    Content type: Research

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  6. Mounting evidence in the cancer literature suggests that microRNAs (miRNAs) influence the progression of human cancer cells by targeting protein-coding genes. How insulin-like growth factor 1(IGF1) and miR-186...

    Authors: Xiurong Lu, Xiao Song, Xiaohui Hao, Xiaoyu Liu, Xianyu Zhang, Na Yuan, Huan Ma and Zhilin Zhang

    Citation: World Journal of Surgical Oncology 2021 19:207

    Content type: Research

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  7. The oncological outcomes of laparoscopic gastrectomy (LG) and open gastrectomy (OG) following neoadjuvant chemotherapy have been investigated in a few studies. Our purpose was to evaluate the oncological outco...

    Authors: Islam Khaled, Pablo Priego, Hany Soliman, Mohammed Faisal and Ihab Saad Ahmed

    Citation: World Journal of Surgical Oncology 2021 19:206

    Content type: Research

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  8. To assess the value of adjuvant radiotherapy for treatment of gastric adenocarcinoma and to investigate subgroups of patients suitable for adjuvant radiotherapy.

    Authors: Peng Wang, Haihua Zhou, Gaohua Han, Qingtao Ni, Shengbin Dai, Junxing Huang, Chunlei Dai and Lei Yu

    Citation: World Journal of Surgical Oncology 2021 19:205

    Content type: Research

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  9. Postoperative infectious complications (ICs) after surgery for colorectal cancer (CRC) increase in-hospital deaths and decrease long-term survival. However, the methodology for IC preoperative and intraoperati...

    Authors: Jing Wen, Tao Pan, Yun-chuan Yuan, Qiu-shi Huang and Jian Shen

    Citation: World Journal of Surgical Oncology 2021 19:204

    Content type: Research

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  10. Radical cystectomy (RC) is the standard treatment for bladder cancer, but the safety and efficacy of this treatment for elderly people need to be considered. We compare perioperative data and survival outcomes...

    Authors: Shangxun Xie, Zihan Zhao, Baofu Feng, Shiwei Zhang, Gutian Zhang, Xiaogong Li, Hongqian Guo and Rong Yang

    Citation: World Journal of Surgical Oncology 2021 19:202

    Content type: Research

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  11. The lymphocyte to C-reactive protein (CRP) ratio (LCR) is an indicator of systemic inflammation and host–tumor cell interactions. The aim of this study was to investigate the prognostic significance of LCR in ...

    Authors: Masaaki Nishi, Mistuo Shimada, Takuya Tokunaga, Jun Higashijima, Kozo Yoshikawa, Hideya Kashihara, Chie Takasu, Daichi Ishikawa, Yuma Wada, Shohei Eto and Toshiaki Yoshimoto

    Citation: World Journal of Surgical Oncology 2021 19:201

    Content type: Research

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  12. The prognosis of patients with colorectal cancer and peritoneal metastasis (CRC-PM) after incomplete cytoreductive surgery (CRS) or palliative surgery is poor. Novel and effective therapies are urgently needed...

    Authors: Tuanhe Sun, Kang Li, Gang Xu, Kun Zhu, Qiong Wang, Chengxue Dang and Dawei Yuan

    Citation: World Journal of Surgical Oncology 2021 19:200

    Content type: Research

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  13. Dysregulation of long non-coding RNAs has been implied to connect with cancer progression. This research was to decipher the mechanism of long non-coding RNA SDCBP2-AS1 in ovarian cancer (OC) through regulatio...

    Authors: Xiu Liu, Chanyuan Liu, Aijun Zhang, Qi Wang, Jiao Ge, Qunying Li and Jinlei Xiao

    Citation: World Journal of Surgical Oncology 2021 19:199

    Content type: Research

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  14. This study was designed to evaluate the safety and effectiveness of a two-hand technique combining harmonic scalpel (HS) and laparoscopic Peng’s multifunction operative dissector (LPMOD) in patients who underw...

    Authors: Jingwei Cai, Guixing Jiang, Yuelong Liang, Yangyang Xie, Junhao Zheng and Xiao Liang

    Citation: World Journal of Surgical Oncology 2021 19:198

    Content type: Research

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  15. Programs of Enhanced Recovery After Surgery reduces morbidity and shorten recovery in patients undergoing colorectal resections for cancer. Patients presenting with more advanced disease such as T4 cancers are...

    Authors: Vittoria Bellato, Yongbo An, Daniele Cerbo, Michela Campanelli, Marzia Franceschilli, Krishn Khanna, Bruno Sensi, Leandro Siragusa, Piero Rossi and Giuseppe S. Sica

    Citation: World Journal of Surgical Oncology 2021 19:196

    Content type: Research

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  16. To describe the techniques and outcomes of complete transperitoneal laparoscopic nephroureterectomy (CTLNU) for upper urinary tract urothelial carcinoma (UTUC) in a single position.

    Authors: Chengwu Xiao, Yang Wang, Meimian Hua, Wei Zhang, Guanyu Ren, Bin Yang and Qing Yang

    Citation: World Journal of Surgical Oncology 2021 19:195

    Content type: Research

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  17. Placement of a self-expanding metal stent (SEMS) in patients presenting with an acute colorectal obstruction (ACO) may obviate emergency surgery (ES), potentially effectively palliating incurable tumors, actin...

    Authors: Fei-hu Yan, Yao Zhang, Cheng-ling Bian, Xiao-shuang Liu, Bing-chen Chen, Zhen Wang, Hao Wang, E. Ji-fu and En-da Yu

    Citation: World Journal of Surgical Oncology 2021 19:194

    Content type: Research

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  18. Desmoplastic small round cell tumor (DSRCT) is a highly malignant sarcoma that occurs in the abdominopelvic cavities of adolescents. The accurate diagnosis of DSRCT is challenging owing to limited literatures....

    Authors: Ling-Ling Wang, Zhong-He Ji, Ying Gao, Hong Chang, Ping-Ping Sun and Yan Li

    Citation: World Journal of Surgical Oncology 2021 19:193

    Content type: Research

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  19. Clinical evidence has proved that enhanced recovery after surgery (ERAS) can improve short-term clinical outcomes after various types of surgeries, but the long-term benefits have not yet been examined, especi...

    Authors: Qianyun Pang, Liping Duan, Yan Jiang and Hongliang Liu

    Citation: World Journal of Surgical Oncology 2021 19:191

    Content type: Review

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  20. The purpose of this study was to evaluate the effects of cytoreductive nephrectomy (CN) and metastasectomies on the survival of patients with synchronous metastatic renal cell cancer (mRCC) using real-life, po...

    Authors: Lauri Laru, Hanna Ronkainen, Pasi Ohtonen and Markku H. Vaarala

    Citation: World Journal of Surgical Oncology 2021 19:190

    Content type: Research

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  21. Understanding the vascular anatomy is critical for performing central vascular ligation (CVL) in right hemicolectomy with complete mesocolic excision (CME). This study aimed to investigate the predictive value...

    Authors: Hui Yu, Yong Zhuang, Jinliang Jian and Chunkang Yang

    Citation: World Journal of Surgical Oncology 2021 19:189

    Content type: Research

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  22. Postoperative symptomatic anastomotic leakage (AL) is a serious complication after low anterior resection (LAR) for rectal cancer. AL can potentially affect short-term patient outcomes and long-term prognosis....

    Authors: Xinyu Qi, Maoxing Liu, Kai Xu, Pin Gao, Fei Tan, Zhendan Yao, Nan Zhang, Hong Yang, Chenghai Zhang, Jiadi Xing, Ming Cui and Xiangqian Su

    Citation: World Journal of Surgical Oncology 2021 19:187

    Content type: Research

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  23. The aim of our study was to observe and compare the curative effect of radiotherapy, chemotherapy, and combined radiotherapy and chemotherapy, as well as comprehensive treatment on superior vena cava syndrome ...

    Authors: Manzhen Sun, Xiaoli Chen, Hongfei Li, Xudong Zhang, Xiaofei Wang, Ruipan Zheng, Guowen Li, Lin Wang and Dianyuan Li

    Citation: World Journal of Surgical Oncology 2021 19:185

    Content type: Research

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  24. Circular RNA low-density lipoprotein receptor-related protein 6 (circLRP6) is considered as an oncogene in many types of cancers. However, the function and mechanisms of circLRP6 in prostate cancer (PCa) tumor...

    Authors: Linghui Qin, Xiaosong Sun, Fei Zhou and Cheng Liu

    Citation: World Journal of Surgical Oncology 2021 19:184

    Content type: Research

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  25. Sentinel lymph node biopsy (SLNB) is the standard approach for the axillary region in early breast cancer patients with clinically negative nodes. The present study investigated patients with false-negative se...

    Authors: Zhu-Jun Loh, Kuo-Ting Lee, Ya-Ping Chen, Yao-Lung Kuo, Wei-Pang Chung, Ya-Ting Hsu, Chien-Chang Huang and Hui-Ping Hsu

    Citation: World Journal of Surgical Oncology 2021 19:183

    Content type: Research

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  26. The prognosis of pancreatic cancer (PC) is extremely poor, and most patients with metastatic PC still receive palliative care. Here, we report the efficacy and safety of FOLFIRINOX (oxaliplatin, irinotecan, le...

    Authors: Beilei Zhang, Fengyan Zhou, Jiaze Hong, Derry Minyao Ng, Tong Yang, Xinyu Zhou, Jieyin Jin, Feifei Zhou, Ping Chen and Yunbao Xu

    Citation: World Journal of Surgical Oncology 2021 19:182

    Content type: Review

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  27. We aimed to develop and validate a radiomics model for differentiating hepatocellular carcinoma (HCC) from focal nodular hyperplasia (FNH) in non-cirrhotic livers using Gd-DTPA contrast-enhanced magnetic reson...

    Authors: Zongren Ding, Kongying Lin, Jun Fu, Qizhen Huang, Guoxu Fang, Yanyan Tang, Wuyi You, Zhaowang Lin, Zhan Lin, Xingxi Pan and Yongyi Zeng

    Citation: World Journal of Surgical Oncology 2021 19:181

    Content type: Research

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  28. There have been many studies on the clinical characteristics of neutrophilic, lymphocytic, and/or eosinophilic pleural effusion. While caring for patients with pleural effusion, we found that histiocytic pleur...

    Authors: Ganghee Chae, Jae-Bum Jun, Hwa Sik Jung, Chui Yong Park, Jin Hyoung Kim, Byung Ju Kang, Hyeon Hui Kang, Seung Won Ra, Kwang Won Seo, Yangjin Jegal, Jong Joon Ahn, Sang Hyuk Park and Taehoon Lee

    Citation: World Journal of Surgical Oncology 2021 19:180

    Content type: Research

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  29. Lymph node metastasis (LNM) is a risk factor for poor long-term outcomes and a prognostic factor for disease-free survival in colon cancer. Preoperative lymph node status evaluation remains a challenge. The pu...

    Authors: Anna Mou, Hang Li, Xiao-li Chen, Yang-hua Fan and Hong Pu

    Citation: World Journal of Surgical Oncology 2021 19:179

    Content type: Research

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  30. Mistletoe extract, used as a complementary chemotherapeutic agent for cancer patients, has anticancer effects against various malignancies. The aim of the present study was to evaluate the effect of mistletoe ...

    Authors: Jeong-Heum Baek, Youngbae Jeon, Kyoung-Won Han, Dong Hae Jung and Kyung-Ok Kim

    Citation: World Journal of Surgical Oncology 2021 19:178

    Content type: Research

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  31. Colon cancer (CC) is a very common gastrointestinal tumor that is prone to invasion and metastasis in the late stage. This study aims to observe the expression of Na+/Ca2+ exchangers (NCXs) and analyze the correl...

    Authors: Zhixiu Xia, Changliang Wang and Hong Zhang

    Citation: World Journal of Surgical Oncology 2021 19:177

    Content type: Research

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  32. Colorectal cancer (CRC) is a common aggressive tumor that poses a heavy burden to human health. An increasing number of studies have reported that circular RNA (circRNA) is involved in the progression of CRC. ...

    Authors: Guojiu Fang, Yibin Wu and Xueli Zhang

    Citation: World Journal of Surgical Oncology 2021 19:176

    Content type: Research

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  33. Repeat hepatectomy and radiofrequency ablation (RFA) are widely used to treat early recurrent hepatocellular carcinoma (RHCC) located in the subcapsular region, but the optimal treatment strategy remains to be...

    Authors: Fuqun Wei, Qizhen Huang, Yang Zhou, Liuping Luo and Yongyi Zeng

    Citation: World Journal of Surgical Oncology 2021 19:175

    Content type: Research

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  34. Despite chemotherapy being a common treatment, an increase in chemoresistance over time is unavoidable. We therefore investigated the role of miR-194-5p in regulating chordoma cell behavior and examined the do...

    Authors: Mengning Xia, Lili Sheng, Wei Qu, Xue Xue, Hucheng Chen, Guoyan Zheng and Weigang Chen

    Citation: World Journal of Surgical Oncology 2021 19:174

    Content type: Research

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  35. Since inflammation and the immune system contribute to the development and progression of malignancies, parameters that reflect a host’s immune-inflammatory status may be useful prognostic indicators of gastri...

    Authors: Hiroyuki Inoue, Toshiyuki Kosuga, Takeshi Kubota, Hirotaka Konishi, Atsushi Shiozaki, Kazuma Okamoto, Hitoshi Fujiwara and Eigo Otsuji

    Citation: World Journal of Surgical Oncology 2021 19:173

    Content type: Research

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  36. The purpose of this letter to the Editor is to report some shortcomings in the statistical analysis and variable grouping in the recent publication of the article “Clinical outcomes of chondroblastoma treated ...

    Authors: Bo-Wen Zheng, Bo-Yv Zheng, Hua-Qing Niu, Xiao-Bin Wang and Jing Li

    Citation: World Journal of Surgical Oncology 2021 19:171

    Content type: Correspondence

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    The original article was published in World Journal of Surgical Oncology 2020 18:47

    The Letter to this article has been published in World Journal of Surgical Oncology 2021 19:172

  37. We retrospectively examined the relationship among skeletal muscle mass index (SMI), prognosis, and chemotherapy side effects in patients with recurrent gastric cancer (RGC).

    Authors: Tomoyuki Matsunaga, Hiroaki Satio, Wataru Miyauchi, Yuji Shishido, Kozo Miyatani, Yuki Murakami, Takehiko Hanaki, Kyoichi Kihara, Manabu Yamamoto, Naruo Tokuyasu, Shuichi Takano, Teruhisa Sakamoto, Toshimichi Hasegawa and Yoshiyuki Fujiwara

    Citation: World Journal of Surgical Oncology 2021 19:170

    Content type: Research

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  38. Interstitial lung disease (ILD) is a rare adverse event in patients receiving adjuvant or neoadjuvant chemotherapy (NAC) for breast cancer. Few studies have reported the frequency of ILD in detail, and only sm...

    Authors: Kenji Tezuka, Kotaro Miura, Yusuke Nakano, Takahiro Ueda, Kyoko Yagyu, Shimako Matsuyama, Masami Shirai, Hiroshi Okuda, Miho Ujikawa and Takayo Ota

    Citation: World Journal of Surgical Oncology 2021 19:169

    Content type: Research

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  39. Sorafenib was reported as a useful adjuvant treatment in patients with hepatocellular carcinoma who underwent surgical resection. However, its therapeutic value remains controversial. This meta-analysis examin...

    Authors: Shenglan Huang, Dan Li, LingLing Zhuang, Liying Sun and Jianbing Wu

    Citation: World Journal of Surgical Oncology 2021 19:168

    Content type: Review

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  40. Elevated plasma D-dimer levels have been reported as an unfavorable prognostic indicator in many solid tumors. However, there are limited relevant studies in pancreatic cancer patients following radical surger...

    Authors: Haoda Chen, Fanlu Li, Siyi Zou, Junjie Xie, Jun Zhang, Xiaxing Deng, Hao Chen and Baiyong Shen

    Citation: World Journal of Surgical Oncology 2021 19:166

    Content type: Research

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  41. Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) has recently emerged as a viable management option for peritoneal surface malignancy (PSM). CRS and HIPEC is a complex, multidi...

    Authors: Suryanarayana Deo, Mukurdipi Ray, Babul Bansal, Sandeep Bhoriwal, Sushma Bhatnagar, Rakesh Garg, Nishkarsh Gupta, Atul Sharma, Lalit Kumar, Sanjay Thulkar, Ekta Dhamija, Sandeep Mathur and Prasenjit Das

    Citation: World Journal of Surgical Oncology 2021 19:164

    Content type: Research

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