Table 1 Perianal Paget’s disease classification and accompanying suggested therapy
Stage | Description | Management |
|---|---|---|
I | Paget’s cells in the perianal epidermis and adnexa without primary carcinoma | Wide local excision |
IIA | Cutaneous Paget’s disease with associated adnexal carcinoma | Wide local excision |
IIB | Cutaneous Paget’s disease with associated anorectal carcinoma | Abdominoperineal resection |
III | Paget’s disease in which associated carcinoma has spread to regional nodes | Inguinal lymph nodes dissection and abdominoperineal resection/wide local excision |
IV | Paget’s disease with distant metastases of associated carcinoma | Chemotherapy, radiotherapy, local palliative management |