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Table 3 Predictive factors for recurrence-free survival

From: Prognosis of papillary thyroid cancer in patients with Graves’ disease: a propensity score-matched analysis

Covariates

Univariate analysis

Multivariate analysis

HR (95% CI)

p value

HR (95% CI)

p value

Clinical features

 Graves’ disease

0.329 (0.046–2.371)

0.270

1.299 (0.170–9.941)

0.801

 Age at surgery (years)

0.981 (0.962–1.001)

0.068

0.983 (0.964–1.001)

0.067

 Male sex

1.092 (0.585–2.037)

0.782

0.669 (0.350–1.277)

0.223

Pathological features

 Tumor size

2.132 (1.822–2.496)

< 0.001

1.585 (1.245–2.018)

< 0.001

 Extrathyroidal extension

  Microscopic

3.146 (1.644–6.021)

0.001

1.674 (0.814–3.441)

0.161

  Gross

10.22 (4.920–21.21)

< 0.001

2.030 (0.931–4.958)

0.120

 Lymphatic invasion

5.520 (3.112–9.793)

< 0.001

1.440 (0.763–2.718)

0.261

 Vascular invasion

4.990 (1.817–13.70)

0.002

1.536 (0.540–4.371)

0.421

 Margin involvement

2.238 (1.144–4.378)

0.019

0.881 (0.400–1.642)

0.560

 LN metastasis

  N1a

3.331 (1.192–7.435)

0.003

3.067 (1.160–8.111)

0.024

  N1b

22.76 (11.76–44.08)

< 0.001

15.65 (6.404–38.25)

< 0.001

131I remnant ablation

4.858 (2.323–10.16)

< 0.001

0.622 (0.223–1.739)

0.366

  1. Data presented as mean and standard deviation if not noted otherwise. Cox proportional hazard model was used for univariate and multivariate analysis for recurrence-free survival
  2. HR hazard ratio, CI confidence interval, LN lymph node
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World Journal of Surgical Oncology

ISSN: 1477-7819

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