- Case report
- Open Access
Surgical management of mediastinal liposarcoma extending from hypopharynx to carina: Case report
© Gethin-Jones et al; licensee BioMed Central Ltd. 2010
- Received: 13 November 2009
- Accepted: 2 March 2010
- Published: 2 March 2010
We describe the complete resection of a giant, well-differentiated mediastinal liposarcoma extending retropharynx to envelop the aortic arch, trachea and esophagus following preoperative radiotherapy.
- Aortic Arch
- Complete Resection
- Pleural Space
- Brachiocephalic Artery
Liposarcomas represent only 1% of all malignancies and are commonly found in the lower limbs and retroperitoneum . Rarely are liposarcomas found in the mediastinum and, of all primary mediastinal sarcomas only 9% are liposarcomas . Several reports suggest radiation and chemotherapy without surgical resection are ineffective treatments for mediastinal liposarcoma despite often daunting preoperative imaging [1, 3]. In this case we report on the surgical resection of a large primary mediastinal liposarcoma by sternotomy.
In the literature, less than 150 cases of primary mediastinal liposarcomas have been reported [1, 4] and because of their rarity, there is no consistent approach to management. Warranting further study, radiology and chemotherapy alone seem to be insufficient forms of treatment but are possibly effective as induction or adjuvant therapies [1, 2, 5]. When determining if surgical intervention is feasible, radiographic films, given the complex anatomy of the mediastinum, can be daunting. However, given the often encapsulated nature of the lesions, complete resection is often possible and debulking can lead to symptomatic relief and often a long-term solution in well-differentiated tumors.
Written informed consent was obtained from the patient for publication of this case report and any accompanying images. A copy of the written consent is available for review by the Editor-in-Chief of this journal.
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