Resection of giant ethmoid osteoma with orbital and skull base extension followed by duraplasty
© Yiotakis et al; licensee BioMed Central Ltd. 2008
Received: 14 March 2008
Accepted: 14 October 2008
Published: 14 October 2008
Osteomas of ethmoid sinus are rare, especially when they involve anterior skull base and orbit, and lead to ophthalmologic and neurological symptoms.
The present case describes a giant ethmoid osteoma. Patient symptoms and signs were exophthalmos and proptosis of the left eye, with progressive visual acuity impairment and visual fields defects. CT/MRI scanning demonstrated a huge osseous lesion of the left ethmoid sinus (6.5 cm × 5 cm × 2.2 cm), extending laterally in to the orbit and cranially up to the anterior skull base. Bilateral extensive polyposis was also found. Endoscopic and external techniques were combined to remove the lesion. Bilateral endoscopic polypectomy, anterior and posterior ethmoidectomy and middle meatus antrostomy were performed. Finally, the remaining part of the tumor was reached and dissected from the surrounding tissue via a minimally invasive Lynch incision around the left middle canthus. During surgery, CSF rhinorrhea was observed and leakage was grafted with fascia lata and coated with bio-glu. Postoperatively, symptoms disappeared. Eighteen months after surgery, the patient is still free of symptoms.
Before management of ethmoid osteomas with intraorbital and skull base extension, a thorough neurological, ophthalmological and imaging evaluation is required, in order to define the bounders of the tumor, carefully survey the severity of symptoms and signs, and precisely plan the optimal treatment. The endoscopic procedure can constitute an important part of surgery undertaken for giant ethmoidal osteomas. In addition, surgeons always have to take into account a possible CSF leak and they have to be prepared to resolve it.
Osteomas are relatively rare, slow-growing, osteogenic tumors. They are the most frequent benign neoplasm of the paranasal sinuses, usually originating in the frontal sinus and much less in ethmoid, sphenoid and maxillary sinus. As osteomas are usually asymptomatic, they are very often incidental radiographic findings, most authors agree that small lesions do not need surgery suggesting periodic imaging in order to follow the growth and allow intervention before the development of complications . Ethmoid osteomas appear early, as the limited anatomical space results to complaining by the patient. Extension to the orbit and/or skull base is unusual. When osteomas expand into the orbital vault, they displace the orbital contents and give rise to adequate symptoms, like headache, and ocular symptoms, such as diplopia, exophthalmos and proptosis.
Surgery is the treatment of choice for symptomatic ethmoid osteomas, however, the approach is under discussion and depends on the extension and the occurrence of complications . Traditional surgical approaches to the involved sinuses are through external frontoethmoidectomy, lateral rhinotomy or osteoplastic flap technique . Technological advantages in endoscopic instrumentation expanded the use of endoscopic surgery for the management of ethmoid osteomas. Endoscopic transnasal resection is ideal for tumors confined to the ethmoid and nasal cavity. The main advantages of the method are the minimal soft tissue dissection, the absence of facial bony disruption, and the avoidance of a facial incision. The magnification and the different angled view, which are possible with the use of endoscopes, may facilitate the removal of osteoma, with minimal morbidity . However, when osteomas are large and expanded in to the orbit and anterior cranial base, a combination of external and endoscopic technique are required, due to the limited access and visibility of endoscopy.
We report a case of a bulky ethmoid sinus osteoma, with anterior skull base and intraorbital expand, treated with a combination of endoscopic and external approach.
We also report the management of SCF linkage presented in the same patient, performing duraplasty with fascia lata.
Although small frontoethmoidal osteomas are relatively frequent, giant osteomas are particularly rare findings in this region . Lesions larger than 3 cm in diameter are considered giant tumors . Due to the serious potential risks of surgery, osteomas of ethmoid sinus can be followed radiographically when they are asymptomatic. Surgery is performed only in the presence of symptoms and signs. Ethmoid osteomas expanded to the orbit and skull base are rare, and they are presenting with neurological and/or ophthalmologic complications like vision disorders, ptosis or headache. In the last cases excision becomes mandatory. Furthermore, surgery has been advocated for osteomas of the ethmoid sinus irrespectively of their size . The surgical approach remains under discussion. Surgical techniques are adapted to different indications. For large ethmoid osteomas lateral rhinotomy, midfacial degloving, osteoplastic flap, external frontoethmoidectomy, and in selected cases, endoscopic excision, are discussed .
A detailed assessment of the margins of the tumor and definition of its relation with the surrounding structures is required in order to choose the most precise approach . A CT scan is a fundamental tool that not only permits diagnosis but also allows the correct surgical approach to be planed. The three-dimensional CT scan is even described as a tool to define the extension of ethmoid osteomas . In our case, careful analysis of CT scan in the axial and coronal view determined the size of the tumor and differentiated osteoma from soft tissue tumors or fibrous displasia. MRI imaging offered more exact evaluation of the margins of the lesion and finely revealed intraorbital extension but not intracranial invasion.
There are conflicting reports about the ability of an osteoma to recur after incomplete removal [11, 12]. Nevertheless, we followed a surgical approach which led to complete removal of an osteoma. We realized that it was not possible to remove radically this huge tumor using endoscopic techniques because it was difficult to control all the tumor boundaries. However, endoscopic sinus surgery was of great help. Performing endoscopic polypectomy and middle meatus antrostomy, we gained visualization without bleeding and without any anatomical structure deformity. Then, via nasoendoscopic approach, the osteoma was drilled out in order to diminish the mass and profit better assess to the edges of the tumor. Although the mass was significantly reduced, detachment of the osteoma under the endoscopic route was not possible due to limited assess to the orbit and skull base. Thus, the remained part of the osteoma was dissected easily and safely with no extensive incision by an external Lynch approach around to medial canthus. Eroded dura was repaired with fascial graft.
There are several reports of successful removal of large ethmoid osteomas with intraorbital extension, treated endoscopically. Huang et al have presented a case of ethoid osteoma extended in to the orbit, which was removed endoscopically after drilling and elevation. Naraghi et al have described a case of large ethmoido-orbital osteoma dissected via endoscopic approach without drilling, with minimal complications. Apart from the much smaller size of the osteomas, in all these cases described above, serious visual or other complications were not quoted. In our patient, osteoma was giant (6.5 cm × 5 cm × 2.2 cm) and the presence of ophthalmologic complications demanded excision of the osteoma instantly.
It is worth mentioning, that this is not the first time that the coexistence of sinus osteoma with nasal polyps is reported. Since the etiology of the two entities is not fully investigated, it is possible that both of them are under the influence of similar etiological factors. In the past, post-traumatic and infectious causes have been discussed, and more recent studies advocate the role of developmental and genetic factors in the pathogenesis of both, nasal polyposis and sinus osteoma. .
Endoscopic surgery meaningfully assists the removal of large osteomas of the ethmoids, minimizing soft tissue dissection and averting facial bony disruption. Surgeons may be faced during operative procedure with a CSF linkage. Therefore, they have to be prepared to repair it.
Written informed consent was taken from the patient for publication of this case report.
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