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Table 4 Clinical and surgical features of 230 pathological (p)N0 patients and 12 skip N2 patients

From: Sialyl Lewis X as a predictor of skip N2 metastasis in clinical stage IA non-small cell lung cancer

  Number of patients Univariate Multivariate
pN0 Skip N2 P-value P-value Odds ratio 95% CI
Age       
  Mean ± SD 66.5 ± 10.2 62.8 ± 11.4 0.268a    
Sex       
  Male 121 6 1.000 NA NA NA
  Female 109 6     
Side       
  Right 131 7 1.000 NA NA NA
  Left 99 5     
Location       
  Upper/Middle lobe 151 6 0.353 NA NA NA
  Lower lobe 79 6     
Histology       
  Ad 192 10 1.000 NA NA NA
  Sq/AdSq 38 2     
Tumor differentiation       
  Well/moderate 181 7 0.146 0.361 1.80 0.49, 6.13
  Poor 49 5     
Tumor diameter (cm)       
  ≤2 113 6 1.000 NA NA NA
  >2 117 6     
sPL factor       
  sPL0 141 6 0.547 NA NA NA
  sPL1-3 89 6     
SLX (U/mL)       
  ≥21.4 121 11 0.007 0.006 9.43 1.75, 175
  <21.4 109 1     
CEA (ng/mL)       
  ≥2.8 143 11 0.060 0.077 4.78 0.87, 89.2
  <2.8 87 1     
Ad: adenocarcinoma   Fisher’s exact test Multivariate logistic regression analysis
Sq: squamous cell carcinoma   aMann-Whitney U-test    
AdSq: adenosquamous carcinoma      
sPL factor: surgical pleural invasion factor      
CI: confidence interval