Sialyl Lewis X as a predictor of skip N2 metastasis in clinical stage IA non-small cell lung cancer

Table 4 Clinical and surgical features of 230 pathological (p)N0 patients and 12 skip N2 patients

	Number of patients		Univariate	Multivariate
	pN0	Skip N2	P-value	P-value	Odds ratio	95% CI
Age
Mean ± SD	66.5 ± 10.2	62.8 ± 11.4	0.268^a
Sex
Male	121	6	1.000	NA	NA	NA
Female	109	6
Side
Right	131	7	1.000	NA	NA	NA
Left	99	5
Location
Upper/Middle lobe	151	6	0.353	NA	NA	NA
Lower lobe	79	6
Histology
Ad	192	10	1.000	NA	NA	NA
Sq/AdSq	38	2
Tumor differentiation
Well/moderate	181	7	0.146	0.361	1.80	0.49, 6.13
Poor	49	5
Tumor diameter (cm)
≤2	113	6	1.000	NA	NA	NA
>2	117	6
sPL factor
sPL0	141	6	0.547	NA	NA	NA
sPL1-3	89	6
SLX (U/mL)
≥21.4	121	11	0.007	0.006	9.43	1.75, 175
<21.4	109	1
CEA (ng/mL)
≥2.8	143	11	0.060	0.077	4.78	0.87, 89.2
<2.8	87	1
Ad: adenocarcinoma			Fisher’s exact test	Multivariate logistic regression analysis
Sq: squamous cell carcinoma			^aMann-Whitney U-test
AdSq: adenosquamous carcinoma
sPL factor: surgical pleural invasion factor
CI: confidence interval

ISSN: 1477-7819