Table 2 Comparison of progression between patients with solitary and multiple PTC
Multiple PTC | solitary PTC | P value | |
|---|---|---|---|
Number | 136 | 376 | |
Male/female | 32/104 | 95/281 | 0.451 |
Mean age (yr) ± SD | 44.3 ± 15.1 | 42.5 ± 17.4 | 0.226 |
Mean size (cm) ± SD | 1.29 ± 1.44 | 1.67 ± 1.15 | 0.048 |
Micro variant | 84 (61.8%) | 147(39.1%) | < 0.001 |
Tall cell variant | 17 (12.5%) | 38 (10.1%) | 0.267 |
Extrathyroidal invasion | 35 (25.9%) | 93 (24.7%) | 0.450 |
Vascular invasion | 15 (11.0%) | 16 (4.3%) | 0.006 |
Hashimoto’s thyroiditis | 36 (26.5%) | 61 (16.2%) | 0.007 |
Lymph node metastasis | 74 (54.4%) | 123 (32.7%) | < 0.001 |
Distant metastasis | 6 (4.4%) | 14 (3.7%) | 0.447 |
Recurrence | 21 (15.4%) | 15 (4.0%) | < 0.001 |
10-year survival rate | 125 (91.9%) | 341 (90.7%) | 0.579 |
BRAFv600E mutation | 75 (55.1%) | 188 (50%) | 0.176 |
Family history | 7 (5.1%) | 6 (1.6%) | 0.032 |
TNM stage | |||
I | 56 (41.2%) | 186 (49.5%) | |
II | 40 (29.4%) | 111 (29.5%) | 0.031 |
III | 24 (17.6%) | 59 (15.7%) | |
IV | 16 (11.8%) | 20 (5.3%) |