Table 2 Univariate and multivariate analysis of OS

Age (older/younger)

1.596 (1.286, 1.982)

< 0.001*

1.750 (1.407, 2.177)

< 0.001*

Sex (male/female)

1.283 (1.028, 1.602)

0.028*

1.093 (0.872, 1.370)

0.440

BMI

0.977 (0.945, 1.010)

0.167

0.970 (0.940, 1.004)

0.080

Diabetes mellitus (yes/no)

1.270 (0.969, 1.665)

0.084

0.985 (0.732, 1.326)

0.922

Hypertension (yes/no)

1.148 (0.902, 1.460)

0.261

1.187 (0.909, 1.551)

0.208

Tumor location (rectum/colon)

1.044 (0.796, 1.371)

0.754

1.144 (0.868, 1.508)

0.341

Tumor differentiation (low/medium/high)

2.234 (1.814, 2.751)

< 0.001*

1.463 (1.174, 1.821)

< 0.001*

Tumor pathological stage (0/I/II/III/IV)

2.203 (1.924, 2.523)

< 0.001*

1.827 (1.579, 2.114)

< 0.001*

Surgical characteristic (R2/R1/R0)

2.140 (1.908, 2.400)

< 0.001*

1.609 (1.412, 1.834)

< 0.001*

Adjuvant chemotherapy (yes/no)

1.190 (0.910, 1.557)

0.204

0.889 (0.665, 1.190)

0.429

Adjuvant radiotherapy (yes/no)

2.301 (1.087, 4.874)

0.030*

0.912 (0.416, 1.997)

0.818