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Table 4 Univariate and multivariate analyses of OS in MBC

From: Clinicopathological characteristics and prognosis of metaplastic breast cancer versus triple-negative invasive ductal carcinoma: a retrospective analysis

 

OS

Univariate analysis

Multivariate analysis

HR

P value

HR

P value

Age ≤ 50

1.48(0.57–3.83)

0.42

  

Premenopausal

1.03(0.40–2.67)

0.96

  

T(T3 + T4)

5.37(1.80–19.71)

 < 0.01

2.39(0.48–11.95)

0.29

LN(positive)

6.15(2.27–16.67)

 < 0.01

3.70(1.03–13.34)

0.04

M(M1)

10.53(2.18–50.85)

 < 0.01

1.42(0.19–10.50)

0.73

AJCC stage(III + IV)

6.04(2.32–15.73)

 < 0.01

1.91(0.51–7.17)

0.34

Subtype(TN-MBC)

0.50(0.16–1.54)

0.22

  

Chemotherapy (yes)

1.78(0.24–13.56)

0.57

  

Radiotherapy (yes)

1.96(0.71–5.40)

0.19

  

endocrine therapy (yes)

1.25(0.17–9.53)

0.83

  

Operation (BCS)

0.63(0.14–2.74)

0.53

  

Operation (SLNB)

0.71(0.26–1.95)

0.51

  
  1. OS overall survival, MBC metaplastic breast cancer, HR hazard ratio, T tumour size, LN lymph node, M distant metastasis at diagnosis, TN-MBC triple-negative metaplastic breast cancer, AJCC American Joint Committee on Cancer, BCS breast-conserving surgery, SLNB sentinel lymph node biopsy