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Table 1 Comparison of clinicopathological features of patients in MBC and TN-IDC

From: Clinicopathological characteristics and prognosis of metaplastic breast cancer versus triple-negative invasive ductal carcinoma: a retrospective analysis

 

MBC

N = 81

TN-IDC

N = 162

P value

Age

0.41

 Mean age (year)

51.07 ± 1.291

52.35 ± 0.876

 

Age

0.93

  ≤ 50

38(47%)

75(46%)

 

  > 50

43(53%)

87(54%)

 

Menstrual state

  

0.20

 Premenopausal

44(54%)

74(46%)

 

 Postmenopausal

37(46%)

88(54%)

 

Tumour size(cm)

  

0.03

  ≤ 2

23(28%)

74(46%)

 

  > 2

50(62%)

78(48%)

 

 Unknown

8(10%)

10(6%)

 

T stage

0.04

 TX

8(10%)

10(6%)

 

 T1

24(30%)

73(45%)

 

 T2

41(50%)

65(40%)

 

 T3

4(5%)

6(4%)

 

 T4

4(5%)

8(5%)

 

LN status

0.04

 Negative

60(74%)

98(60%)

 

 Positive

21(26%)

64(40%)

 

N stage

  

0.03

 N0

60(74%)

98(60%)

 

 N1

10(12%)

30(19%)

 

 N2

7(9%)

14(9%)

 

 N3

4(5%)

20(12%)

 

Distant metastasis

1.00

 No

79(98%)

159(98%)

 

 Yes

2(2%)

3(2%)

 

AJCC stage

0.58

 I

20(25%)

56(35%)

 

 II

43(53%)

62(38%)

 

 III

10(13%)

31(19%)

 

 IV

2(2%)

3(2%)

 

 Unknown

6(7%)

10(6%)

 

AJCC stage

0.20

 I+II

63

118

 

 III

10

31

 

Subtype

 Triple negative

68(84%)

162

 

 HR( −) HER-2( +)

7(9%)

0

 

 HR( +) HER-2( −)

6(7%)

0

 

Chemotherapy

0.12

 Yes

72(89%)

153(94%)

 No

9(11%)

9(6%)

Chemotherapy modalities

0.29

 Postoperative chemotherapy

55(76%)

126(82%)

 Preoperative chemotherapy

17(24%)

27(18%)

Radiotherapy

0.38

 Yes

41(51%)

70(43%)

 No

35(43%)

85(53%)

 Unknown

5(6%)

7(4%)

Endocrine therapy

 Yes

5(6%)

0(0)

 No

76(94%)

162(100%)

Anthracycline therapy

0.62

 Yes

64(89%)

133(87%)

 No

6(8%)

16(10%)

 Unknown

2(3%)

4(3%)

Taxane therapy

0.41

 Yes

64(89%)

142(93%)

 No

6(8%)

7(5%)

 Unknown

2(3%)

4(2%)

Platinum therapy

0.26

 Yes

9(13%)

12(8%)

 No

61(85%)

137(90%)

 Unknown

2(2%)

4(2%)

Operation

0.91

 Mastectomy

66(81%)

133(82%)

 BCS

15(19%)

29(18%)

Operation

0.41

 ALND

42(52%)

93(57%)

 SLNB

39(48%)

69(43%)

  1. MBC metaplastic breast cancer, TN-IDC triple-negative invasive ductal carcinoma, T tumour size, LN lymph node, N nodal size, AJCC American Joint Committee on Cancer, HR hormone receptor, HER-2 human epidermal growth factor receptor-2, BCS breast-conserving surgery, ALND axillary lymph node dissection, SLNB sentinel lymph node biopsy