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Table 3 Sensitivity and specificity of WLE, NBI endoscopy and endoscopic iodine staining compared with histopathological results

From: Application of narrow band imaging and Lugol's iodine staining in screening for nasopharyngeal carcinoma

 

Sensitivity (%)

Specificity (%)

PPV (%)

NPV (%)

AUC

95%CI

p

Accuracy (%)

WLE

72.414

75.385

39.623

92.453

0.739

0.664–0.805

 < 0.01

74.843

NBI

65.517

85.385

50.000

91.376

0.755

0.680–0.819

 < 0.01

81.761

Iodine staining

82.759

81.538

50.000

95.495

0.821

0.753–0.878

 < 0.01

81.761

Combined prediction

85.000

91.367

58.621

97.692

0.912

0.857–0.951

 < 0.01

90.566

  1. WLE White light endoscopy, NBI Narrow band imaging, PPV Positive predictive value, NPV Negative predictive value, AUC Area under curve
  2. Note: p < 0.05 for conventional WLE, endoscopic iodine staining, or NBI vs. combined prediction