Fig. 5

FOXM1 expression in HCC subgroups based on high throughput sequencing analysis. The expression of FOXM1 mRNA was significantly higher in HCC patients with younger ages and poorer tumor status. A Age. B Race. C Tumor status. D American Joint Committee on Cancer pathologic stage. HCC patients were grouped into two groups by using the surv_cutpoint function in survminer (version 0.4.9). The prognostic value of FOXM1 was confirmed by using TCGA (E) and in-house immunohistochemistry (F). AA, African American; AI, American Indian; AN, Alaska native. *p < 0.05; **p < 0.01; ***p < 0.001; NS, not significant