Fig. 1

FOXM1 expression in non-HCC and HCC samples based on in-house immunohistochemistry. The expression status and clinicopathological significance of FOXM1 protein were explored in non-HCC samples (A, B) and HCC samples (C, D). E FOXM1 protein expression in the HCC group was obviously elevated. F Increased expression of FOXM1 protein could be used to discriminate HCC from non-HCC tissue. G, H Increased expression of FOXM1 protein could be found in HCC tissue with advanced tumor status and lymphatic metastasis. *p < 0.05; **p < 0.01; ***p < 0.001; NS, not significant