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Table 3 Comparison of SLC5A8 gene methylation in patients with different clinical features in baseline

From: Role of hypermethylated SLC5A8 in follicular thyroid cancer diagnosis and prognosis prediction

Variables

n

Positive (n = 92)

Negative (n = 73)

χ2

P

Age

  < 45

110

59(53.6)

51(46.4)

0.602

0.438

  ≥ 45

55

33(60.0)

22(40.0)

  

Sex

 Male

74

42(56.8)

32(43.2)

0.054

0.816

 Female

91

50(54.9)

41(45.1)

  

Tumor size

  < 1.0 cm

71

41(57.7)

30(42.3)

0.200

0.655

  ≥ 1.0 cm

94

51(54.3)

43(45.7)

  

TG

  < 40 μg/L

91

42(46.2)

49(53.8)

7.586

0.006

  ≥ 40 μg/L

74

50(67.6)

24(32.4)

  

Chol

  < 5.17 mmol/L

114

57(50.0)

57(50.0)

4.956

0.026

  ≥ 5.17 mmol/L

51

35(68.6)

16(31.4)

  

Triglycerides

  < 1.7 mmol/L

134

73(54.5)

61(45.5)

0.474

0.491

  ≥ 1.7 mmol/L

31

19(61.3)

12(38.7)

  

Pathological type

 FTC

58

42(72.4)

16 (27.6)

13.063

0.001

 FTA

67

27(40.3)

40 (59.7)

  

 TT-UMP

40

23(57.5)

17 (42.5)

  
  1. Positive means SLC5A8 gene hypermethylation; negative means SLC5A8 gene un-hypermethylation. If the sample has both u and m bands, we will delete the sample and not include this data in the result