Table 3 Univariate and Multivariate analysis for predictors of disease-free survival

Gender (Male)

1.45(0.82–2.55)

0.198

Age (≥ 60 years)

1.28(0.78–2.09)

0.333

CEA (> 5 ng/ml)

2.01(1.13–3.59)

0.018

2.34(1.30 – 4.21)

0.005

PNI (presence)

1.7(1.04–2.77)

0.034

1.70(1.04 – 2.8)

0.035

Vascular invasion (Presence)

1.16(0.66–2.05)

0.604

Location (Ref: Lower)

 Middle

2.86(1.54–5.31)

 < 0.001

3.26(1.73 – 6.14)

 < 0.001

 Upper

0.96(0.47–1.99)

0.916

0.96(0.46—1.99)

0.904

 EGJ

1.48(0.73–2.99)

0.273

1.57(0.77—3.18)

0.211

Tumor diameter (> 3 cm)

0.73(0.45–1.18)

0.200

Type of gastrectomy (Total)

1.2(0.74–1.95)

0.460

Adjuvant chemotherapy (Yes)

0.6(0.36–1)

0.048

0.52(0.31—0.86)

0.011

Differentiation type (Poorly differentiated)

1.11(0.62–1.98)

0.727

Lauren classification (Ref: Intestinal)

 Diffuse

1.29(0.71–2.36)

0.402

 Mix

1.1(0.55–2.19)

0.781

 Others

0.39(0.1–1.45)

0.159

T Stage (T3/T4a)

1.66(0.76–3.65)

0.205

Lymph node metastasis (presence)

1.33(0.81–2.16)

0.258