Table 1 Cases of tumor-to-tumor metastasis from RCC to thyroid carcinoma
Author | Age | Gender | Recipient thyroid neoplasm | Size of thyroid neoplasm | Time interval to diagnosis of metastatic disease | IHCresults of metastatic RCC | Treatment |
|---|---|---|---|---|---|---|---|
Badawi et al. [3] | 63 | F | FVPTC | Multinodular, largest 1.9 cm | 14 years | CD10, PAX-8, CAIX, galectin-3, and vimentin ( +) | Total thyroidectomy |
TG, TTF-1, CK7, CK19 ( −) | |||||||
Kefeli et al. [5] | 80 | F | FVPTC | 4 cm | 18 years | PAX-8, CD10, vimentin ( +) | Left thyroidectomy |
TG, TTF-1, GATA-3, PTH hormone, chromogranin-A, CEA, calcitonin ( −) | |||||||
Manini et al. [8] | 42 | M | FVPTC | 5 cm | Synchronous | CD10, PAX-8, and CAIX ( +) | Total thyroidectomy |
Medas et al. [9] | 62 | F | FA | Multinodular, largest 5.3 cm | 6 years | CD10 ( +) | Total thyroidectomy |
TG, TTF-1, galectin-3 ( −) | |||||||
Qian et al. [10] | 53 | F | Hürthle cell adenoma | 2 cm | Synchronous | Vimentin, CD10 ( +) | Total thyroidectomy |
TG, TTF ( −) | |||||||
Baloch et al. [11] | 78 | M | FVPTC | Multiple nodules, size not reported | 2 years | NA | NA |
Bohnv et al. [12] | 68 | M | Papillary thyroid carcinoma | 2.5 cm | 2 years | RCC ( +) | Total thyroidectomy |
TG ( −) | |||||||
Koo et al., cited by Bohn [12] | 48 | F | FA | 3 cm | 5 years | Keratin (not further specified), CD10, galacetin-3 (+) | NA |
TG, TTF-1, calcitonin, inhibin ( −) | |||||||
Rosai et al., cited by Bohn [12] | NA | NA | FA | NA | NA | TG ( −) | NA |
Ryska et al. [13] | 52 | M | Oncocytic Hürthle cell carcinoma | Multinodular, largest 2.5 cm | 13 months | Keratin AE1/AE3, vimentin, EMA ( +) | Total thyroidectomy |
TG, CEA, calcitonin, cytokeratin 19 ( −) | |||||||
Wolf et al. [14] | 60 | F | FA | 3 cm | 2 years | NA | Left lobectomy |
Yu et al. [15] | 61 | M | FVPTC | Multinodular largest 6 cm | 3 years | Keratin CAM 5.2, CD10, vimentin( +) | Total thyroidectomy |
TG, TTF-1, RCC, p63 ( −) | |||||||
Ghossein et al. [16] | 65 | F | FVPTC | 1.1 cm |  − 2 monthsa | NA | Thyroid lobectomy |
Chacho et al. [17] | 72 | F | FA | 2 cm | Synchronous | NA | NA |
Gawlik et al. | 63 | F | FVPTC | 2.5 cm | 13 months | PAX-8 ( +) | Left lobectomy |
TG, TTF-1, chromogranin, synaptophysin ( −) |