Table 4 Subgroup analysis of OS and DFS in 255 patients with SLM after NAC
Clinical indicators | Time interval (TI) after NAC to surgery (no. of patients) | OS (mean survival time) | P value | DFS (mean disease-free time) | P value |
|---|---|---|---|---|---|
Age | |||||
Age < 60 | 4≦TI < 6 (N = 61) | 35.94 months | 0.055 | 29.43 months | 0.113 |
6≦TI≦8 (N = 64) | 28.35 months | 21.73 months | |||
Age ≥ 60 | 4≦TI < 6 (N = 71) | 35.37 months | 0.011* | 27.93 months | 0.002* |
6≦TI≦8 (N = 59) | 26.22 months | 18.91 months | |||
Chronic disease | |||||
Yes | 4≦TI < 6 (N = 52) | 37.46 months | 0.012* | 28.64 months | 0.019* |
6≦TI≦8 (N = 46) | 28.45 months | 20.25 months | |||
No | 4≦TI < 6 (N = 80) | 34.50 months | 0.045* | 29.29 months | 0.014* |
6≦TI≦8 (N = 77) | 27.74 months | 20.34 months | |||
Anemia (M:Hb < 120 g/L,F:Hb < 110 g/L) | |||||
Yes | 4≦TI < 6 (N = 64) | 35.75 months | 0.052 | 25.98 months | 0.063 |
6≦TI≦8 (N = 45) | 26.39 months | 19.29 months | |||
No | 4≦TI < 6 (N = 68) | 36.16 months | 0.030* | 31.63 months | 0.007* |
6≦TI≦8 (N = 78) | 27.49 months | 20.32 months | |||
Preoperative jaundice | |||||
Yes | 4≦TI < 6 (N = 73) | 36.39 months | 0.062 | 30.94 months | 0.001* |
6≦TI≦8 (N = 40) | 27.50 months | 16.92 months | |||
No | 4≦TI < 6 (N = 59) | 34.18 months | 0.036* | 26.63 months | 0.069 |
6≦TI≦8 (N = 83) | 27.50 months | 22.92 months | |||
Exclude non-R0 resection | 4≦TI < 6 (N = 125) | 35.44 months | 0.007* | 29.45 months | 0.002* |
6≦TI≦8 (N = 110) | 27.88 months | 20.27 months | |||