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Table 3 Short-term clinical outcomes of patients before and after propensity score matching

From: Timing of surgery in patients with synchronous colorectal cancer liver metastases undergoing neoadjuvant chemotherapy: a propensity score analysis

Outcomes

Before PSM

P value

After PSM

P value

4TI < 6 (n = 132)

6TI8 (n = 123)

4TI < 6 (n = 94)

6TI8 (n = 94)

Operation time (min)

279.5 (251, 295)

287 (268, 303)

0.020*

278 (245.25, 296)

287.5 (272, 305)

0.015*

Intraoperative hemorrhage (ml)

700 (500, 1000)

650 (500, 850)

0.284

725 (500, 1000)

700 (537.5, 850)

0.703

Intraoperative transfusion

50 (37.9)

35 (28.5)

0.111

33 (35.1)

30 (31.9)

0.643

Overall postoperative complications

90 (68.2)

60 (48.8)

0.002*

69 (73.4)

44 (46.8)

< 0.001*

Overall postoperative infection

41 (31.1)

23 (18.7)

0.023*

32 (34.0)

18 (19.1)

0.021*

Sepsis

4 (3.0)

0 (0.0)

0.149

3 (3.2)

0 (0.0)

0.244

Incision infection

5 (3.8)

5 (4.1)

1.000

3 (3.2)

4 (4.3)

1.000

Abdominal infection

6 (4.5)

5 (4.1)

0.850

5 (5.3)

4 (4.3)

1.000

Pulmonary infection

29 (22.0)

14 (11.4)

0.024*

23 (24.5)

11 (11.7)

0.023*

Pleural effusion

39 (29.5)

17 (13.8)

0.002*

32 (34.0)

13 (13.8)

0.001*

Gastrointestinal dysfunction

17 (12.9)

8 (6.5)

0.087

15 (16.0)

7 (7.4)

0.070

Intestinal anastomosis leak

4 (3.0)

3 (2.4)

1.000

3 (3.2)

3 (3.2)

1.000

Liver failure

5 (3.8)

2 (1.6)

0.501

3 (3.2)

2 (2.1)

1.000

Ascites

11 (8.3)

21 (17.1)

0.035*

8 (8.5)

16 (17.0)

0.080

Jaundice

13 (9.8)

3 (2.4)

0.015*

6 (6.4)

3 (3.2)

0.494

Bile leakage

8 (6.1)

14 (11.4)

0.130

5 (5.3)

11 (11.7)

0.117

Postoperative hemorrhage

15 (11.4)

7 (5.7)

0.107

13 (13.8)

2 (2.1)

0.003*

Postoperative hospital stay

7 (6,9)

7 (6,9)

0.868

7 (5.75, 8)

7 (6, 9)

0.307

Clavien-Dindo Grade

  

0.011*

  

0.003*

 I

28 (21.2)

11 (8.9)

 

24 (25.5)

9 (9.6)

 

 II

39 (29.5)

36 (29.3)

 

28 (29.8)

25 (26.6)

 

 IIIa

3 (2.3)

3 (2.4)

 

2 (2.1)

3 (3.2)

 

 IIIb

12 (9.1)

8 (6.5)

 

9 (9.6)

5 (5.3)

 

 IV

7 (5.3)

2 (1.6)

 

6 (6.4)

2 (2.1)

 
  1. Continuous variables with normal distribution are presented as mean value ± SD while others are presented as median (IQR). Categorical variables are presented as frequency (percentage) unless otherwise stated
  2. *p<0.05