Table 2 Baseline characteristics after propensity score matching
Covariates | Time interval (TI) after NAC to surgery | P value | |
|---|---|---|---|
4≦TI < 6 (n = 94) | 6≦TI≦8 (n = 94) | ||
Sex (M:F) | 61:33 | 60:34 | 0.879 |
Age (years) | 61 (54, 66) | 59 (54, 67.25) | 0.435 |
Over weight (BMI > 24) | 22 (23.4) | 25 (26.6) | 0.613 |
Diabetes | 17 (18.1) | 13 (13.8) | 0.426 |
Hypertension | 26 (27.7) | 20 (21.3) | 0.309 |
Coronary heart disease | 4 (4.3) | 4 (4.3) | 1.000 |
Liver cirrhosis | 7 (7.4) | 6 (6.4) | 0.774 |
NAC cycles | 4 (3,5) | 4 (3,5) | 0.597 |
NAC regimes | 0.800 | ||
FOLFIRI | 24 (25.5) | 28 (29.8) | |
CapeOX | 32 (34.0) | 31 (33.0) | |
FOLFOX | 38 (40.4) | 35 (37.2) | |
Progressive disease during NAC | 11 (11.7) | 9 (9.6) | 0.636 |
Toxic reactions after NAC | 5 (5.3) | 3 (3.2) | 0.470 |
Serum CEA (> 10 ng/mL) | 79 (84.0) | 78 (83.0) | 0.844 |
Hemoglobin (g/L) | 123 (100, 136.8) | 121 (99.9, 134.7) | 0.581 |
WBC (109/L) | 6.0 (4.8, 7.1) | 6.1 (4.6, 8.0) | 0.198 |
PLT (109/L) | 118.8 (80.1, 157.5) | 117.8 (83.3, 165.3) | 0.740 |
Total bilirubin (μmol/L) | 17.3 (11.7, 20.7) | 15.4 (12.2, 20.8) | 0.782 |
Albumin (g/L) | 38.8 (34.6, 43.4) | 38.2 (33.7, 44.3) | 0.242 |
AST (IU/L) | 37.5 (28.0, 53.3) | 42 (30, 65.3) | 0.680 |
ALT (IU/L) | 32.0 (21.8, 50.3) | 39 (25, 66) | 0.779 |
Primary tumor | |||
Tumor size (cm) | 3.6 (2.5, 5.0) | 3.4 (2.6, 4.5) | 0.289 |
Tumor location (left:right) | 53:41 | 49:45 | 0.558 |
Number of tumors | 1 (1, 1) | 1 (1, 1) | 0.651 |
Tumor grade (medium/high:low) | 58:36 | 59:35 | 0.880 |
Nerve invasion | 21 (22.3) | 19 (20.2) | 0.722 |
Cancer nodule | 0 (0, 1) | 0 (0, 1) | 0.727 |
Lymph node metastasis | 41 (43.6) | 39 (41.5) | 0.768 |
Liver metastases | |||
Tumor size (cm) | 3.5 (2.2, 5.0) | 3.5 (2.4, 4.5) | 0.439 |
Number of tumors | 1 (1, 2) | 2 (1, 2.3) | 0.095 |
Tumor grade (medium/high:low) | 60:34 | 61:33 | 0.879 |
Liver capsule invasion | 35 (37.2) | 34 (36.2) | 0.880 |
Portal vein tumor thrombus | 7 (7.4) | 6 (6.4) | 0.774 |
Vascular tumor thrombus | 26 (27.7) | 20 (21.3) | 0.309 |
Satellite nodules | 12 (12.8) | 13 (13.8) | 0.830 |
Extrahepatic invasion | 10 (10.6) | 8 (8.5) | 0.620 |
Surgical procedure | |||
ASA grade ≥ 3 | 3 (3.2) | 3 (3.2) | 1.000 |
R0 resection | 87 (92.6) | 85 (90.4) | 0.601 |
Major liver resection | 22 (23.4) | 28 (29.8) | 0.322 |