Variables | Univariable | Multivariable | ||
---|---|---|---|---|
P value | HR | 95% CI | P value | |
Primary treatment | ||||
Emergency surgerya | 0.53 | 0.88 | ||
Time interval of < 11 days | 0.99 | 0.96 | 0.41–2.26 | 0.99 |
Time interval of 11–17 days | 0.99 | 0.80 | 0.38–1.71 | 0.99 |
Time interval of > 17 days | 0.43 | 1.02 | 0.43–2.44 | 0.99 |
Age | 0.004 | 1.03 | 1.01–1.05 | 0.013 |
Sex | ||||
Malea/female | 0.11 | |||
BMI | 0.90 | |||
ASA | ||||
I–IIa/III | 0.038 | 1.79 | 0.90–3.57 | 0.10 |
Preoperative CEA | 0.028 | 1.17 | 0.98–1.41 | 0.09 |
Location | ||||
Righta | 0.34 | |||
Left | 0.99 | |||
Rectum | 0.44 | |||
Pathologic size | 0.76 | |||
Differentiation | ||||
Undifferentiated | 0.67 | |||
Pathologic stage | ||||
I–IIa/III | < 0.001 | 1.76 | 0.99–3.12 | 0.05 |
Lymphatic invasion | ||||
Present | 0.011 | 1.12 | 0.67–1.86 | 0.66 |
Venous invasion | ||||
Present | < 0.001 | 1.84 | 1.06–3.21 | 0.031 |
Peri-neural invasion | ||||
Present | 0.014 | 1.64 | 0.99–2.70 | 0.05 |
Microsatellite instability test | ||||
Low or stablea/high | 0.18 | |||
Adjuvant chemotherapy | 0.23 |