Variables | Univariable | Multivariable | ||
---|---|---|---|---|
P | HR | 95% CI | P | |
Primary treatment | ||||
Emergency surgerya | 0.95 | 0.034 | ||
Time interval of < 11 days | 0.99 | 0.82 | 0.38–1.75 | 0.99 |
Time interval of 11–17 days | 0.99 | 0.48 | 0.24–0.97 | 0.036 |
Time interval of > 17 days | 0.99 | 0.44 | 0.17–1.10 | 0.09 |
Age | < 0.001 | 1.06 | 1.03–1.08 | < 0.001 |
Sex | ||||
Malea/female | 0.13 | |||
BMI | 0.93 | |||
ASA | ||||
I–IIa/III | < 0.001 | 1.93 | 0.97–3.82 | 0.06 |
Preoperative CEA | < 0.001 | 1.32 | 1.11–1.58 | 0.002 |
Location | ||||
Righta | 0.29 | |||
Left | 0.99 | |||
Rectum | 0.62 | |||
Pathologic size | 0.19 | |||
Differentiation | ||||
Undifferentiated | 0.48 | |||
Pathologic stage | ||||
I–IIa/III | 0.06 | 0.90 | 0.52–1.58 | 0.72 |
Lymphatic invasion | ||||
Present | 0.011 | 1.56 | 0.95–2.55 | 0.08 |
Venous invasion | ||||
Present | < 0.001 | 2.79 | 1.60–4.88 | < 0.001 |
Peri-neural invasion | ||||
Present | 0.51 | |||
Microsatellite instability test | ||||
Low or stablea/high | 0.20 | |||
Adjuvant chemotherapy | < 0.001 | 0.74 | 0.44–1.23 | 0.24 |