Fig. 1

GREM1 expression characteristics analysis. A Volcano plot of the DEGs. The red and blue dots represent the significantly upregulated and significantly down-regulated genes in BCa. B The difference expression of GREM1 in BCa tissues and adjacent normal tissues. C The difference expression of GREM1 in BCa tissues and paired normal tissues. D GREM1 expression profile across multiple cancer samples and normal tissues. E GREM1 expression profile across multiple cancer samples and paired normal tissues. F Representative immunohistochemistry of GREM1 in BCa tissues and adjacent normal tissues. G Western blot of GREM1 protein expression in BCa tissues and adjacent normal tissues. *p < 0.05, **p < 0.01, ***p < 0.001