Skip to main content

Table 2 Results of meta-analysis comparing AR and PSR for CRLM

From: Clinical outcomes of parenchymal-sparing versus anatomic resection for colorectal liver metastases: a systematic review and meta-analysis

  

Patients

  

Study heterogeneity

 

Outcomes of interest

Studies

AR

PSR

WMD/RR/HR (95% CI)

P value

I2(%)

P value

Effect model

Long-term

 Overall survial (OS)

22

3154

4074

1.08(0.95–1.22)

0.245

49.3

0.005

Random

 3‐year OS

13

1668

2878

0.99(0.92–1.06)

0.728

55.4

0.008

Random

 5‐year OS

18

2760

3692

0.93(0.86–1.00)

0.054

44.9

0.021

Random

 Disease‐free survival (DFS)

14

2260

3368

1.09(0.94–1.28)

0.259

75.1

 < 0.001

Random

 3‐year DFS

10

1237

2581

0.98(0.89–1.07)

0.66

0

0.897

Fixed

 5‐year DFS

14

2260

3368

0.88(0.73–1.07)

0.212

70.1

 < 0.001

Random

 3‐year Liver-RFS

5

386

496

1.02(0.9–1.15)

0.789

0

0.79

Fixed

 5‐year Liver-RFS

5

386

496

1.00(0.88–1.14)

0.981

0

0.592

Fixed

Short‐term

 Duration of operation (min)

13

1234

1364

51.48(29.03–73.93)

 < 0.001

98.6

 < 0.001

Random

 Estimated blood loss (mL)

10

886

992

189.92(21.39–358.45)

0.027

98.6

 < 0.001

Random

 Intraoperative blood transfusion

12

1799

3004

2.24(1.54–3.26)

 < 0.001

74

 < 0.001

Random

 Length of hospital stay (day)

15

1813

3011

1.00(0.34–1.67)

0.003

66.6

 < 0.001

Random

 Positive margin (mm)

12

1244

1080

0.77(0.61–0.97)

0.024

33.9

0.119

Fixed

 Postoperative complications

12

1880

3116

2.28(1.88–2.77)

 < 0.001

0

0.639

Fixed

 90‐day mortality

7

1711

2826

3.08(1.88–5.03)

 < 0.001

0

0.796

Fixed

 Intrahepatic recurrence

15

2299

2036

0.90(0.82–0.98)

0.021

26.2

0.166

Fixed

 Repeat hepatectomy

14

2362

3398

0.64(0.55–0.76)

 < 0.001

12.4

0.317

Fixed

  1. Abbreviations: AR Anatomic resection, CI Confidence interval, CRLM Colorectal liver metastases, DFS Disease-free survival, HR Hazard ratio, RR Risk ratio, OS Overall survival, PSR Parenchymal-sparing resection, RFS Recurrence‐free survival, WMD Weighted mean difference