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Table 3 Clinical and 3DVE features associated with R0 resection in patients with hilar cholangiocarcinoma detected at 3D visualization and evaluation

From: Three-dimensional visualization and evaluation of hilar cholangiocarcinoma resectability and proposal of a new classification

  

Resection margin status

Univariable analysis

Multivariable analysis

Clinical and 3DVE features

Total no. of Patients

R0

R1/R2/

Unresectable

Odds ratio (95% CI)

P value

Adjusted

odds ratio (95% CI)

P value

Age

  > 60 years

83

55(66.3%)

28(33.7%)

    

  ≤ 60 years

28

16(57.1%)

12(42.9%)

1.5(0.6,3.5)

0.386

  

Sex

 Male

68

44(64.7%)

24(35.3%)

    

 Female

43

27(62.8%)

16(37.2%)

1.1(0.5, 2.4)

0.838

  

Tumor size

  < 1 cm

4

3(75.0%)

1(25.0%)

1

   

 1 ~ 3 cm

63

43(68.6%)

20(31.7%)

1.4(0.1,14.3)

0.779

  

  ≥ 3 cm

44

25(56.8%)

19(43.2%)

2.3(0.2, 23.7)

0.490

  

Hepatic artery involvement

 Absent

43

35(81.4%)

8(18.6%)

    

 Present

68

36(52.9%)

32(47.1%)

3.9(1.6, 9.6)

0.003

3.5(1.4, 8.8)

0.008

Portal vein involvement

 Absent

61

41(67.2%)

20(32.8%)

    

 Present

50

30(60.0%)

20(40.0%)

1.4(0.6.3.0)

0.432

  

Bismuth-Corlette Classification

 I

21

13(61.9%)

8(38.1%)

    

 II

21

15(71.4%)

6(28.6%)

0.7(0.2, 2.4)

0.514

  

 III

54

33(61.1%)

21(38.9%)

1.0(0.4, 2.9)

0.949

  

 IV

15

10(66.7%)

5(33.3%)

0.8(0.2, 3.3)

0.769

  

Lymph node metastasis

 Absent

50

37(74.0%)

13(26.0%)

    

 Present

61

34(55.7%)

27(44.3%)

2.3(1.0, 5.1)

0.048

1.9(0.8, 4.3)

0.149

Hepatic atrophy

 Absent

88

58(65.9%)

30(34.1%)

    

 Present

23

13(56.5%)

10(43.5%)

1.5(0.6, 3.8)

0.405

  

P point involvement

 Absent

96

60(62.5%)

36(37.5%)

1

/

  

 Present

15

11(73.3%)

4(26.7%)

0.6(0.2, 2.0)

0.420

  

U point involvement

 Absent

92

62(67.4%)

30(32.6%)

    

 Present

19

9(47.4%)

10(52.6%)

2.3(0.8, 6.2)

0.103

  
  1. Unless otherwise indicated, data are number of patients and data in parentheses are percentages. CI confidence interval