Table 1 Clinicopathological features of 111 patients of hilar cholangiocarcinoma

No. of patients

111

80

31

Age (years)^a

65 ± 10

66 ± 9

62 ± 11

0.053

Sex (M/F)

68/43

51/29

17/14

0.387

Preoperative biliary drainage

20/91

17/63

3/28

0.155

Tumor size(≤ 1/1 ~ 3 cm/ ≥ 3 cm

8/45/58

6/35/39

2/10/19

0.488

Tumor form

0.016

 Sclerosing

43

35

8

 Mass

50

32

18

 Polypoid

9

9

0

 Mixed

9

4

5

Tumor differentiation (well/moderately/poorly)

3/80/28

2/59/19

1/21/9

0.818

Hepatic artery involvement^b

57(52.3%)

34(42.5%)

23(79.3%)

 < 0.001

Portal vein involvement^c

55(50.0%)

31(38.6%)

24(80.0%)

 < 0.001

Hepatic vein involvement

5(4.5%)

3(3.8%)

2(6.5%)

0.538

Lymph node metastasis^d

54(49.1%)

31(38.8%)

23(76.7%)

 < 0.001

Distant metastasis

5(4.5%)

1(1.3%)

4(12.9%)

0.008

Perineural invasion

56(50.5%)

35(43.8%)

21(67.7%)

0.023

Hepatic lobe atrophy

21(18.9%)

10(12.5%)

11(35.5%)

0.006

Resection status

 < 0.001

 R0

71(64.9%)

63(78.8%)

8(25.8%)

 R1

15(13.5%)

15(18.8%)

0(0.0%)

 R2

7(6.3%)

1(1.2%)

6(19.4%)

 Unresectable

18(16.2%)

1(1.2%)

17(54.8%)