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Fig. 1 | World Journal of Surgical Oncology

Fig. 1

From: Carbon nanoparticles localized clipped node dissection combined with sentinel lymph node biopsy with indocyanine green and methylene blue after neoadjuvant therapy in node positive breast cancer in China: initial results of a prospective study

Fig. 1

The procedure for marking the biopsy-proven metastatic lymph nodes with clips and carbon nanoparticles (CNs) guided by ultrasound. A An abnormal lymph node was found by ultrasonography and confirmed by fine-needle biopsy. B The process of placing a Bard clip propeller in the biopsy-proven node, and the arrow shows the puncture route. C The hyperechoic clip (arrow) in the hypoechoic lymph node. D The clip (arrow) inside the axillary lymph node detected by preoperative chest computed tomography. E After 2 courses of neoadjuvant therapy, the clip (arrow) in the lymph node can be seen by ultrasonography. F Because of fibrosis after neoadjuvant therapy, it was difficult to distinguish the clip by preoperative ultrasound after 6 courses of neoadjuvant therapy. G After the injection of 0.05 ml CNs, a hyperechoic region (circle) appeared around the clip

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