Table 2 Univariate analysis and multivariate Cox proportional hazards regression of training set using a stepwise-selection method

Age

0.99 (0.96–1.02)

SCC-Ag (ng/ml)

  ≤ 11.5

Reference

Reference

  > 11.5

2.59 (1.51–4.44)

1.91 (1.07–3.42)

Tumor volume (cm³)

  ≤ 28.8

Reference

Reference

  > 28.8

3.89 (2.00–7.56)

2.84 (1.40–5.74)

Poor differentiation

 No

Reference

Reference

 Yes

2.33 (1.29–4.18)

2.81 (1.52–5.19)

Hemoglobin concentration (g/L)

  ≥ 120

Reference

 90 g/L ~ 119

2.10 (1.12–3.94)

  < 90

2.49 (1.10–5.64)

Parametrial invasion

 No

Reference

 Parametrial invasion

1.20 (0.36–4.03)

 Pelvic wall extension

2.19 (0.67–7.18)

FIGO2018 stage

 II

Reference

Reference

 IIIa and IIIb

1.99 (0.79–5.05)

1.42 (0.55–3.70)

 IIIc1r

3.80 (1.73–8.34)

2.45 (1.07–5.60)

 IIIc2r

6.20 (2.25–17.12)

4.26 (1.49–12.17)

Chemotherapy

 No

Reference

Reference

 Yes

0.71 (0.38–1.32)

0.50 (0.27–0.96)

Radiotherapy modality

 Conventional radiotherapy

Reference

 IMRT

1.26 (0.74–2.16)

Time of radiotherapy(day)

  ≤ 56

Reference

  > 56

1.37 (0.76–2.47)

EQD₂ dose of point A (Gy)

  ≤ 85

Reference

  > 85

1.60 (0.69–3.75)