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Table 1 Patients’ characteristics for both training set and validation set

From: A prognostic model using FIGO 2018 staging and MRI-derived tumor volume to predict long-term outcomes in patients with uterine cervical squamous cell carcinoma who received definitive radiotherapy

Variables

Training set

n = 277

Validation set

n = 119

P value

Age (year, mean ± standard deviation)

55.0 ± 9.5

54.2 ± 9.9

0.4622

SCC-Ag

  

0.708

  ≤ 11.5 ng/ml

200 (72.20%)

83 (69.75%)

 

 11.5 ng/ml

77 (27.80%)

36 (30.25%)

 

Tumor volume (cm3)

  

0.6936

  ≤ 28.85

131 (47.29%)

53 (44.54%)

 

  > 28.85

146 (52.71%)

66 (55.46%)

 

Poor differentiation

  

0.853

 No

229 (82.67%)

100 (84.03%)

 

 Yes

48 (17.33%)

19 (15.97%)

 

Hemoglobin concentration (g/L)

  

0.4388

  ≥ 120

209 (75.45%)

83 (69.75%)

 

 90 g/L ~ 119

46 (16.61%)

26 (21.85%)

 

  < 90

22 (7.94%)

10 (8.40%)

 

Parametrial invasion

  

0.6113

 No

24 (8.66%)

10 (8.40%)

 

 Parametrial invasion

139 (50.18%)

66 (55.46%)

 

 Pelvic wall extension

114 (41.16%)

43 (36.13%)

 

FIGO2018 stage

  

0.4027

 II

97 (35.02%)

49 (41.18%)

 

 IIIa and IIIb

64 (23.10%)

19 (15.97%)

 

 IIIc1r

99 (35.74%)

43 (36.13%)

 

 IIIc2r

17 (6.14%)

8 (6.72%)

 

Chemotherapy

  

0.5438

 No

53 (19.13%)

19 (15.97%)

 

 Yes

224 (80.87%)

100 (84.03%)

 

Radiotherapy modality

  

0.6598

 Conventional radiotherapy

157 (56.68%)

71 (59.66%)

 

 IMRT

120 (43.32%)

48 (40.34%)

 

Time of radiotherapy(day)

  

0.3521

  ≤ 56

101 (36.46%)

50 (42.02%)

 

  > 56

176 (63.54%)

69 (57.98%)

 

EQD2 dose of point A (Gy)

  

0.8446

  ≤ 85

45 (16.25%)

21 (17.65%)

 

  > 85

232 (83.75%)

98 (82.35%)

 

Status

  

0.6846

 Alive/Censored

224 (80.87%)

99 (83.19%)

 

 Dead

53 (19.13%)

20 (16.81%)

 
  1. SCC-Ag squamous cell carcinoma antigen, FIGO International Federation of Gynecology and Obstetrics, IMRT intensity modulated radiation therapy, EQD2 2-Gy equivalent dose