Fig. 2

Silencing of SOX21-AS1 inhibits the proliferation, migration, and invasion and promotes the apoptosis of EC cells. HEC-1A and Ishikawa cells were treated with sh-SOX21-AS1 and sh-NC, respectively. A The expression of SOX21-AS1 measured by RT-qPCR. B CCK8 assay detected cell viability. C Colony formation assay. D Cell migration and invasion measured through transwell assay. E Flow cytometry detected cell apoptosis. F The protein levels of apoptosis-related genes. ^**P < 0.01,^***P < 0.001