Table 2 Univariate and multivariate analysis of overall survival in gastric cancer (GC) patients who underwent gastrectomy in the training cohort

Gender

 Male/female

0.921

1.020

0.692–1.504

Age

 > 60 years/ ≤ 60 years

0.181

0.817

0.608–1.099

ASA

 II/I

0.714

0.920

0.587–1.440

ECOG PS

 1/0

0.984

1.004

0.706–1.427

TNM stage

< 0.001

1.711

1.490–1.965

< 0.001

1.584

1.365–1.837

Tumor size

0.002

1.594

1.182–2.149

0.119

1.283

0.938–1.755

 > 5.0 cm/ ≤ 5.0 cm

Vascular invasion

0.427

1.131

0.835–1.531

 Yes/No

P53

< 0.001

2.298

1.682–3.140

0.005

1.862

1.205–2.880

 ± 

Ki-67

 ≥ / < 

< 0.001

2.614

1.923–3.555

0.027

1.606

1.055–2.444

MSI status

 MSI-high/MSS or MSI-low

 < 0.001

2.710

1.880–3.907

< 0.001

2.771

1.864–4.121