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Table 4 Univariate and multivariate analysis of overall survival in gastric cancer patients with outlet obstruction

From: Is vagotomy necessary in palliative surgery for incurable advanced gastric cancer?: a retrospective case–control study

Variables

Total (n = 84)

LUGC (n = 22)

GCDM (n = 62)

Univariate

Multivariate

Univariate

Multivariate

Univariate

HR (95% CI)

P value

HR (95% CI)

P value

HR (95% CI)

P value

HR (95% CI)

P value

HR (95% CI)

P value

Age ≥ 65

1.63 (1.02–2.60)

0.040

1.42 (0.88–2.29)

0.156

2.83 (0.97–8.29)

0.058

  

1.49 (0.87–2.55)

0.148

Male

0.95 (0.55–1.63)

0.846

  

0.83 (0.27–2.54)

0.738

  

0.95 (0.51–1.77)

0.859

Chemotherapy

0.27 (0.15–0.48)

0.000

0.31 (0.16–0.57)

0.000

0.18 (0.05–0.66)

0.009

0.10 (0.03–0.43)

0.002

0.21 (0.10–0.44)

0.000

Poorly cohesive (ref. adenocarcinoma)

1.71 (0.99–2.97)

0.056

  

1.61 (0.56–4.67)

0.378

  

1.84 (0.96–3.52)

0.067

Albumin ≥ 3.5 g/dL

1.22 (0.76–1.97)

0.411

  

1.25 (0.49–3.16)

0.654

  

1.20(0.69–2.11)

0.514

Vagotomy

0.85 (0.54–1.34)

0.487

  

0.38 (0.15–0.98)

0.045

0.25 (0.09–0.68)

0.007

1.14 (0.67–1.94)

0.642

Comorbidity ≥ 3

2.21 (1.10–4.41)

0.025

1.32 (0.64–2.74)

 

3.76 (0.98–14.38)

0.369

  

1.96 (0.86–4.43)

0.567

Laparoscopy

1.07 (0.67–1.72)

0.775

  

1.25 (0.46–3.39)

0.664

  

0.98 (0.57–1.69)

0.952

Postoperative complication

1.99 (0.95–4.19)

0.069

  

3.80 (0.78–18.45)

0.097

  

1.81 (0.77–4.26)

0.177

GCDM (ref. LUGC)

0.69 (0.41–1.17)

0.166

        
  1. Abbreviations: LUGC Locally unresectable gastric cancer, GCDM Gastric cancer with distant metastasis
  2. All values are presented as the hazard ratio (HR) and 95% confidence interval for HR
  3. p values were obtained by the cox-proportional hazard model