From: Prediction of nonsentinel lymph node metastasis in breast cancer patients based on machine learning
Characteristics | Univariate | Multivariate | ||
---|---|---|---|---|
 | OR (95% CI) | P | OR (95% CI) | P |
Age (median [IQR]) | 1 (0.98–1.02) | 0.935 |  |  |
Position (%) | Â | Â | Â | Â |
 Left | 1 |  |  |  |
 Right | 1.03 (0.75–1.41) | 0.856 |  |  |
BMI (%) | Â | Â | Â | Â |
 < 18.5 | 1 |  |  |  |
 18.5–23.9 | 0.59 (0.22–1.61) | 0.306 |  |  |
 24–27.9 | 0.77 (0.28–2.11) | 0.608 |  |  |
 ≥ 28 | 0.95 (0.34–2.62) | 0.917 |  |  |
Pregnant (%) | Â | Â | Â | Â |
 0 | 1 |  |  |  |
 1 | 1.02 (0.48–2.17) | 0.961 |  |  |
 ≥ 2 | 0.85 (0.39–1.87) | 0.691 |  |  |
Menopause (%) | Â | Â | Â | Â |
 No | 1 |  |  |  |
 Yes | 1.1 (0.81–1.51) | 0.542 |  |  |
Nipple retraction (%) | Â | Â | Â | Â |
 No | 1 |  |  |  |
 Yes | 1.41 (0.7–2.84) | 0.338 |  |  |
Nipple discharge (%) | Â | Â | Â | Â |
 No | 1 |  |  |  |
 Yes | 0.45 (0.13–1.59) | 0.216 |  |  |
Number of tumor (%) | Â | Â | Â | Â |
 Single focal | 1 |  |  |  |
 Multi-focal | 1.51 (0.92–2.49) | 0.104 |  |  |
cT (%) | Â | Â | Â | Â |
 1 | 1 |  |  |  |
 2 | 1.31 (0.95–1.81) | 0.095 |  |  |
 3 | 1.04 (0.35–3.07) | 0.942 |  |  |
 4 | 2.29 (0.32–16.49) | 0.411 |  |  |
Aspect ratio (%) | Â | Â | Â | Â |
 < 1 | 1 |  |  |  |
 > 1 | 1.35 (0.7–2.59) | 0.369 |  |  |
 = 1 | 1.26 (0.41–3.91) | 0.684 |  |  |
US tumor borderline (%) | Â | Â | Â | Â |
 Clear | 1 |  |  |  |
 Lack of clarity | 1.46 (0.79–2.68) | 0.228 |  |  |
 Blurring | 1.46 (0.84–2.56) | 0.181 |  |  |
US tumor form (%) | Â | Â | Â | Â |
 Rule | 1 |  |  |  |
 Underrule | 0.82 (0.3–2.26) | 0.699 |  |  |
 Irregularity | 1.45 (0.71–2.94) | 0.308 |  |  |
US tumor blood (%) | Â | Â | Â | Â |
 No | 1 |  |  |  |
 Yes | 1.03 (0.69–1.54) | 0.895 |  |  |
cN | Â | Â | Â | Â |
 cN0 | 1 |  |  |  |
 cN1/cN2/cN3 | 1.5 (1.07–2.09) | 0.018 | 1.22 (0.86–1.74) | 0.269 |
US BI-RADS (%) | Â | Â | Â | Â |
 3 | 1 |  |  |  |
 4 | 2.02 (0.57–7.18) | 0.277 |  |  |
 5 | 3.4 (0.92–12.57) | 0.067 |  |  |
 6 | 2.89 (0.32–25.7) | 0.341 |  |  |
MG calcification (%) | Â | Â | Â | Â |
 No | 1 |  |  |  |
 Yes | 1.15 (0.8–1.65) | 0.453 |  |  |
MG BI-RADS (%) | Â | Â | Â | Â |
 3 | 1 |  |  |  |
 4 | 1.77 (1.02–3.05) | 0.041 | 1.68 (0.95–2.97) | 0.077 |
 5 | 1.88 (0.97–3.66) | 0.063 | 1.92 (0.96–3.86) | 0.067 |
 6 | 1.03 (0.36–2.95) | 0.955 | 0.9 (0.3-2.7) | 0.849 |
SLNs group (%) | Â | Â | Â | Â |
 Negative | 1 |  |  |  |
 Positive | 2.38 (1.3–4.36) | 0.005 | 1.64 (0.88–3.05) | 0.119 |
Ratio of no. of positive SLNs to total no. of SLNs (%) | Â | Â | Â | Â |
 ≤ 0.5 | 1 |  |  |  |
 > 0.5 | 3.82 (2.69–5.43) | < 0.001 | 3.51 (2.43–5.05) | < 0.001 |