Skip to main content

Table 2 Relationship between training set characteristics and NSLNM

From: Prediction of nonsentinel lymph node metastasis in breast cancer patients based on machine learning

Characteristics

Univariate

Multivariate

 

OR (95% CI)

P

OR (95% CI)

P

Age (median [IQR])

1 (0.98–1.02)

0.935

  

Position (%)

    

 Left

1

   

 Right

1.03 (0.75–1.41)

0.856

  

BMI (%)

    

 < 18.5

1

   

 18.5–23.9

0.59 (0.22–1.61)

0.306

  

 24–27.9

0.77 (0.28–2.11)

0.608

  

 ≥ 28

0.95 (0.34–2.62)

0.917

  

Pregnant (%)

    

 0

1

   

 1

1.02 (0.48–2.17)

0.961

  

 ≥ 2

0.85 (0.39–1.87)

0.691

  

Menopause (%)

    

 No

1

   

 Yes

1.1 (0.81–1.51)

0.542

  

Nipple retraction (%)

    

 No

1

   

 Yes

1.41 (0.7–2.84)

0.338

  

Nipple discharge (%)

    

 No

1

   

 Yes

0.45 (0.13–1.59)

0.216

  

Number of tumor (%)

    

 Single focal

1

   

 Multi-focal

1.51 (0.92–2.49)

0.104

  

cT (%)

    

 1

1

   

 2

1.31 (0.95–1.81)

0.095

  

 3

1.04 (0.35–3.07)

0.942

  

 4

2.29 (0.32–16.49)

0.411

  

Aspect ratio (%)

    

 < 1

1

   

 > 1

1.35 (0.7–2.59)

0.369

  

 = 1

1.26 (0.41–3.91)

0.684

  

US tumor borderline (%)

    

 Clear

1

   

 Lack of clarity

1.46 (0.79–2.68)

0.228

  

 Blurring

1.46 (0.84–2.56)

0.181

  

US tumor form (%)

    

 Rule

1

   

 Underrule

0.82 (0.3–2.26)

0.699

  

 Irregularity

1.45 (0.71–2.94)

0.308

  

US tumor blood (%)

    

 No

1

   

 Yes

1.03 (0.69–1.54)

0.895

  

cN

    

 cN0

1

   

 cN1/cN2/cN3

1.5 (1.07–2.09)

0.018

1.22 (0.86–1.74)

0.269

US BI-RADS (%)

    

 3

1

   

 4

2.02 (0.57–7.18)

0.277

  

 5

3.4 (0.92–12.57)

0.067

  

 6

2.89 (0.32–25.7)

0.341

  

MG calcification (%)

    

 No

1

   

 Yes

1.15 (0.8–1.65)

0.453

  

MG BI-RADS (%)

    

 3

1

   

 4

1.77 (1.02–3.05)

0.041

1.68 (0.95–2.97)

0.077

 5

1.88 (0.97–3.66)

0.063

1.92 (0.96–3.86)

0.067

 6

1.03 (0.36–2.95)

0.955

0.9 (0.3-2.7)

0.849

SLNs group (%)

    

 Negative

1

   

 Positive

2.38 (1.3–4.36)

0.005

1.64 (0.88–3.05)

0.119

Ratio of no. of positive SLNs to total no. of SLNs (%)

    

 ≤ 0.5

1

   

 > 0.5

3.82 (2.69–5.43)

< 0.001

3.51 (2.43–5.05)

< 0.001

  1. Abbreviations: BMI Body mass index, US Ultrasound, MG Mammography, SLN Sentinel lymph node