Fig. 4

MiR-132-3p in exosomes aggravated interstitial lung disease development in vivo. A Representative histological lung sections were subjected to H&E and Masson staining and immunohistochemical analysis for α-SMA from saline, BLM, BLM + Exo, BLM + miR-NC-exo, and BLM + miR-132-3p inhibitor-exo groups. B In all groups, α-SMA, COL1A1, COL3A1, and TGF-β1 mRNA expressions were tested by qRT-PCR analysis. C In saline, BLM, BLM + Exo, BLM + miR-NC-exo, and BLM + miR-132-3p inhibitor-exo groups, the mRNA expressions of IL-1β/6/8 were tested. Data were presented as mean ± SD of three independent experiments. ***P < 0.001; **P < 0.01