The value of frozen section diagnosis of tumor spread through air spaces in small-sized (≤ 2 cm) non-small cell lung cancer

Table 2 Diagnostic performance of frozen sections to detect STAS (n = 294)

Grouping	Diagnosis of STAS in frozen sections	Diagnosis of STAS in paraffin sections
Grouping	Diagnosis of STAS in frozen sections	Positive	Negative	Total
All	Positive	59	28	87	Sensitivity: 55.14%
	Negative	48	159	207	Specificity: 85.02%
	Total	107	187	294	Kappa = 0.418 (moderate)
CTR ≤ 0.5	Positive	17	12	29	Sensitivity: 45.94%
	Negative	20	91	111	Specificity: 88.34%
	Total	37	103	140	Kappa = 0.368 (low)
CTR > 0.5	Positive	42	16	58	Sensitivity: 60.00%
	Negative	28	68	96	Specificity: 80.95%
	Total	70	84	154	Kappa = 0.415 (moderate)
Tdmax ≤ 1 cm	Positive	8	5	13	Sensitivity: 57.14%
	Negative	6	34	40	Specificity: 87.17%
	Total	14	39	53	Kappa = 0.454 (moderate)
Tdmax > 1 cm	Positive	51	23	74	Sensitivity: 54.83%
	Negative	42	125	167	Specificity: 84.45%
	Total	93	148	241	Kappa = 0.408 (moderate)

STAS Tumor spread through air spaces, CTR Consolidation tumor ratio, Tdmax Maximum tumour diameter

ISSN: 1477-7819