Fig. 4

Hypoxia-relevant risk score correlates to clinicopathologic features and independently and reliably predicts HCC prognosis. A-F Comparison of risk score between different clinicopathologic factors: gender, T, N, M stage, histologic grade, and pathologic stage in TCGA-LIHC dataset. G, H Relationship of risk score with age, and tumor purity across TCGA-LIHC patients. I Distribution of alive and dead status in low- and high-risk patients. J Distribution of disease free and recurred/progressed status in two groups. K, L Uni- and multivariate cox regression results on risk score and clinicopathologic factors with TCGA-LIHC prognosis. M-O ROCs at one-, three- and five-year survival in the training, test and total datasets. P, Q ROCs in the LICA-FR, and LIRI-JP datasets. ***P<0.001; ****p<0.0001; ns: no significance