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Fig. 3 | World Journal of Surgical Oncology

Fig. 3

From: Metformin increases pathological responses to rectal cancers with neoadjuvant chemoradiotherapy: a systematic review and meta-analysis

Fig. 3

The summary of odds ratios of pCR, TRG, T downstaging, and N downstaging between DM patients with metformin (DM + /MF +) and DM patients without metformin (DM + /MF −). Oh (2016) has two cohorts: Oh 2016 (neoadjuvant CRT followed by surgical resection from 2007 to 2011) and Oh 2016’ (neoadjuvant CRT followed by surgical resection from 2012 to 2014)

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