Table 5 Clinicopathological and treatment characteristics associated with CA19-9 value after surgery
From: Factors predicting recurrence after left‑sided pancreatectomy for pancreatic ductal adenocarcinoma
Variables | High CA19-9(N = 49) | Normal CA19-9 (N = 48) | P value |
|---|---|---|---|
Age(years) | 0.319 | ||
≤ 74 | 38(77.6%) | 41(85.4%) | |
≥ 75 | 11(22.4%) | 7(14.6%) | |
Sex (%) | 0.184 | ||
Male | 33(67.3%) | 26(54.2%) | |
Female | 16(32.7%) | 22(45.8%) | |
BMI (kg/m2) | 0.414 | ||
≤ 18.4 | 4(8.2%) | 2(4.2%) | |
≥ 18.5 | 45(91.8%) | 46(95.8%) | |
Surgical procedure | |||
RAMPS | 25(51%) | 18(37.5%) | 0.180 |
DP | 24(29%) | 30(62.5%) | |
T stage | |||
T1-2 | 27(55.1%) | 36(75%) | 0.040 |
T3-4 | 22(44.9%) | 12(25%) | |
N stage | |||
N0 | 25(51%) | 30(62.5%) | 0.254 |
N1-2 | 24(29%) | 18(37.5%) | |
Tumor differentiation | |||
Well /moderate | 18(36.7%) | 29(60.4%) | 0.020 |
Poor | 31(63.3%) | 19(39.6%) | |
R-status | 0.316 | ||
R1 | 3 (6.1%) | 1(2.1%) | |
R0 | 46(93.9%) | 46(97.9%) | |
Perineural invasion | 0.075 | ||
Yes | 42(85.7%) | 34(70.8%) | |
No | 7(14.3%) | 14(29.2%) | |
Lymphovasular invasion | 0.334 | ||
Yes | 21(42.9%) | 16(33.3%) | |
No | 28(57.1%) | 32(66.7%) | |
PFS (months) | 6.8 (95%CI 5.04–8.56) | 12.6 (95%CI 10.52–14.68) | 0.002 |
OS (months) | 15.2 (95%CI 13.22–17.25) | 22.9 (95%CI 16.41–29.38) | 0.003 |