Table 3 Relationship among MHR, tumor markers and pathological features of CRC

Tumor stage

 I

0.60 (0.22–3.12)

0.941

2.68 (0.55–114.6)

 < 0.001

6.45 (2.00–183.31)

0.001

 II

0.29 (0.06–1.68)

3.39 (0.5–125.08)

12.75 (0.00–430.00)

 III

0.62 (0.22–1.09)

4.43 (0.75–64.07)

9.80 (0.03–460.00)

 IV

0.59 (0.18–2.25)

18.28 (1.22–160.25)

143.19 (0.20–693.55)

Lymph node metastasis

 Absence

0.53 (0.08–2.46)

0.593

3.03 (0.50–114.60)

0.004

9.73 (0.00–430.00)

 < 0.001

 Presence

0.52 (0.16–1.79)

5.68 (0.75–160.25)

11.27 (0.03–693.55)

Tumor location

 Rectum

0.55 (0.08–1.76)

0.166

3.73 (0.50–143.46)

0.890

11.6 (0.00–693.55)

0.233

 Colon

0.50 (0.15–2.46)

3.79 (0.91–160.25)

9.49 (2.00–655.22)

Tumor size

  < 5 cm

0.52 (0.08–2.46)

0.850

3.33 (0.55–143.46)

0.013

8.76 (0.00–693.55)

0.013

  ≥ 5 cm

0.54 (0.18–1.46)

4.77 (0.50–160.25)

17.13 (0.03–525.72)

Tumor differentiation

 Senior

0.51 (0.08–1.79)

0.049

3.36 (0.55–143.46)

0.149

9.28 (2.00–411.51)

0.368

 Middle + Low

0.57 (0.18–2.46)

3.92 (0.50–160.25)

11.02 (0.00–693.55)

Tumor type

 Mass

0.50 (0.18–2.46)

0.407

3.24 (0.75–77.70)

0.017

11.51 (2.00–161.30)

0.685

 Infiltration + Ulcers

0.54 (0.08–1.56)

4.12 (0.50–160.25)

10.33 (0.00–693.55)

Occult blood test

 Negative

0.54 (0.20–1.56)

0.683

3.73 (0.55–77.7)

0.811

9.88 (2.00–525.72)

0.651

 Positive

0.53 (0.08–2.46)

3.79 (0.50–160.25)

10.93 (0.00–693.55)