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Table 2 Univariate analysis of relationship between peripheral hematology and treatment effect

From: Prognostic roles of hematological indicators for the efficacy and prognosis of immune checkpoint inhibitors in patients with advanced tumors: a retrospective cohort study

Hematological index

PD group

PR + SD group

t/Z

P

PR group

SD + PD group

t//Z

P

WBC (× 109/L)

(6.37 ± 3.27)

(6.07 ± 3.02)

 − 0.048

0.962

(6.31 ± 3.09)

(5.95 ± 3.04)

 − 1.846

0.065

ANC (× 109/L)

(4.44 ± 3.48)

(4.00 ± 2.45)

 − 0.350

0.726

(4.50 ± 1.57)

(1.03 ± 2.65)

 − 1.744

0.081

ALC (× 109/L)

(1.16 ± 1.11)

(1.34 ± 0.78)

 − 1.206

0.228

(1.35 ± 0.80)

(1.25 ± 0.84)

 − 0.669

0.503

AMC (× 109/L)

(0.44 ± 0.26)

(0.39 ± 0.24)

 − 0.519

0.604

(0.40 ± 0.29)

(0.37 ± 0.23)

 − 0.622

0.534

RBC (× 109/L)

(4.91 ± 11.00)

(4.56 ± 7.36)

 − 0.025

0.025

(4.27 ± 0.55)*

(4.06 ± 0.82)

 − 2.681

0.007

Hb (g/L)

(122.30 ± 17.83)

(129.00 ± 26.00)

 − 2.401

0.016

(134.0 ± 26.8)

(125.95 ± 24.7)

 − 2.863

0.004

PLT (× 109/L)

(207.50 ± 122)

(248.61 ± 94)

 − 0.601

0.548

(223.0 ± 87)

(229.50 ± 103)

 − 0.325

0.746

AEC (× 109/L)

(0.07 ± 0.09)

(0.10 ± 0.12)

-2.068

0.039

(0.12 ± 0.16)

(0.09 ± 0.11)

 − 1.068

0.286

ABC (× 109/L)

(0.02 ± 0.03)

(0.04 ± 0.02)

 − 0.386

0.700

(0.03 ± 0.02)

(0.02 ± 2.65)

 − 1.563

0.118

PAB# (mg/L)

(200.67 ± 73.36)*

(210.84 ± 69.22)*

 − 1.398

0.163

(214.47 ± 29.03)*

(205.24 ± 72.30)*

 − 0.970

0.334

ALB (g/L)

(40.15 ± 3.36)*

(41.10 ± 4.75)

 − 2.600

0.009

(40.52 ± 3.88)*

(40.75 ± 5.38)

 − 0.305

0.761

NLR

(3.49 ± 2.72)

(3.14 ± 2.81)

 − 1.437

0.151

(3.30 ± 3.28)

(3.25 ± 2.49)

 − 0.458

0.647

PLR

(161.10 ± 124.54)

(183.87 ± 141.75)

 − 0.436

0.663

(171.21 ± 133.24)

(175.38 ± 131.65)

 − 0.009

0.993

MLR

(0.33 ± 0.23)

(0.30 ± 0.25)

 − 1.832

0.067

(0.29 ± 0.33)

(0.30 ± 0.23)

 − 0.455

0.649

SIRI

(1.53 ± 1.58)

(1.13 ± 1.73)

 − 1.421

0.155

(1.40 ± 1.94)

(1.20 ± 1.50)

 − 0.577

0.564

NER

(57.21 ± 96.06)

(40.90 ± 63.54)

 − 2.480

0.013

(39.92 ± 91.85)

(48.37 ± 68.23)

 − 0.319

0.750

PNI

(46.01 ± 5.33)*

(47.29 ± 6.05)

 − 2.422

0.015

(47.75 ± 5.29)*

(47.35 ± 6.20)

 − 0.572

0.568

  1. SD Stable disease, PR Partial response, Hb Hemoglobin, RBC Red blood cell, WBC White blood cell, ANC Absolute neutrophil counter, ALC Absolute lymphoblastic counter, AMC Absolute monocyte counter, PLT Platelet, AEC Absolute eosinophil count, ABC Absolute basophil count, PAB Prealbumin, ALB Albumin, NLR Neutrophil–lymphocyte ratio, PLR Platelet-lymphocyte ratio, MLR Monocyte-lymphocyte ratio, SIRI Systemic inflammatory response index, NER Neutrophil-eosinophil ratio, PNI Prognostic nutritional index
  2. P < 0.05 is statistically significant; conformed to normal distribution marked as *; conformed to homogeneity of variance marked as #