Table 1 Clinical features of patients
Clinical characteristics | Cases | Proportion (%) |
|---|---|---|
Age (years) | ||
  < 62 | 210 | 48.3 |
  ≥ 62 | 225 | 51.7 |
BMIa | ||
  < 23.8 | 219 | 50.7 |
  ≥ 23.8 | 213 | 49.3 |
PD-L1b | ||
 Positive | 95 | 21.8 |
 Negative | 63 | 14.5 |
 Unknown | 277 | 63.7 |
Sex | ||
 Male | 295 | 67.8 |
 Female | 140 | 32.2 |
Treatment line | ||
 First line | 221 | 50.8 |
 Second line | 103 | 23.6 |
 Multi-line | 111 | 25.6 |
Smoking | ||
 Yes | 196 | 45.1 |
 No | 239 | 54.9 |
Drinking | ||
 Yes | 165 | 37.9 |
 No | 270 | 62.1 |
Liver metastasis | ||
 Yes | 155 | 35.6 |
 No | 280 | 64.4 |
Brain metastasis | ||
 Yes | 68 | 15.4 |
 No | 367 | 84.6 |
The number of organs transferred | ||
 1 | 255 | 58.6 |
 2 | 129 | 29.7 |
  ≥ 3 | 51 | 11.7 |
PS | ||
 0–1 | 417 | 95.9 |
  ≥ 2 | 18 | 4.1 |
Efficacy evaluation | ||
 PD | 138 | 31.7 |
 SD | 236 | 54.3 |
 PR | 61 | 14 |
Tumor type | ||
 Lung cancer | 167 | 38.3 |
 Gastric cancer | 77 | 17.7 |
 Esophageal cancer | 47 | 10.8 |
 Colon cancer | 33 | 7.6 |
 Bladder cancer | 3 | 0.7 |
 Bile duct cancer | 6 | 1.4 |
 Gallbladder cancer | 4 | 0.9 |
 Liver cancer | 11 | 2.5 |
 Cervical cancer | 15 | 3.4 |
 Ovarian cancer | 3 | 0.7 |
 Breast cancer | 11 | 2.5 |
 Kidney cancer | 7 | 1.6 |
 Head and neck cancer | 13 | 3 |
 Pancreatic cancer | 13 | 3 |
 Original unknown cancer | 13 | 3 |
 Endometrial cancer | 7 | 1.6 |
 Affiliated organs such as skin | 5 | 1.1 |
Pathological type | ||
 Adenocarcinoma | 217 | 49.9 |
 Squamous cell carcinoma | 105 | 24.1 |
 Small lung cancer | 41 | 9.4 |
 Malignant melanoma | 4 | 0.9 |
 Sarcoma | 8 | 1.8 |
 Urothelial carcinoma | 4 | 0.9 |
 Neuroendocrine carcinoma | 6 | 1.4 |
 Signet-ring cell carcinoma | 3 | 0.7 |
 Adenosquamous carcinoma | 5 | 1.1 |
 Hepatocellular carcinoma | 2 | 0.5 |
 Cholangiocarcinoma | 3 | 0.7 |
 Large cell carcinoma | 2 | 0.5 |
 Others | 30 | 6.9 |
Combined treatment | ||
 Yes | 373 | 85.7 |
 No | 62 | 14.3 |
Drug | ||
 PD-1 | 416 | 95.7 |
 PD-L1 | 19 | 4.3 |