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Table 4 Multivariate analyses of 102 women with 2018 FIGO stage IIIC1p cervical cancer with regard to OS and DFS

From: Prognostic analysis of patients with stage IIIC1p cervical cancer treated by surgery

Variables

OS

DFS

HR (95% CI)

p value

HR (95% CI)

p value

Postoperative treatment (reference: none)

-

-

-

-

 Chemotherapy

0.235 (0.094 ~ 0.587)

0.002

0.357 (0.144 ~ 0.886)

0.026

 Chemo plus radiotherapy

0.078 (0.028 ~ 0.220)

 < 0.001

0.115 (0.041 ~ 0.321)

 < 0.001

Ovarian status (reference: ovarian transposition)

1.730 (0.706 ~ 4.237)

0.231

1.658 (0.708 ~ 3.883)

0.244

Perioperative complications (reference: none)

1.527 (0.753 ~ 3.098)

0.241

1.392 (0.699 ~ 2.773)

0.347

LNR (reference: ≤ 0.3)

4.299 (2.203 ~ 8.389)

 < 0.001

3.797 (2.003 ~ 7.197)

 < 0.001

LVSI (reference: negative)

1.959 (0.896 ~ 4.282)

0.092

1.481 (0.709 ~ 3.093)

0.296

Parametrium (reference: negative)

1.058 (0.442 ~ 2.532)

0.899

1.369 (0.589 ~ 3.180)

0.466

NLR (reference: ≤ 3.8)

2.129 (1.046 ~ 4.334)

0.037

2.402 (1.208 ~ 4.778)

0.013

  1. LNR Lymph node ratio, LVSI Lymph vascular space invasion, NLR Neutrophil–lymphocyte ratio, CI Confidence intervals, HR Hazard ratio