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Table 3 Univariate analyses of 102 women with 2018 FIGO stage IIIC1p cervical cancer with regard to OS and DFS

From: Prognostic analysis of patients with stage IIIC1p cervical cancer treated by surgery

Variables

OS

DFS

HR (95% CI)

p value

HR (95% CI)

p value

Age (reference: ≤ 54)

0.738(0.375 ~ 1.454)

0.380

0.688(0.351 ~ 1.350)

0.276

Postoperative treatment (reference: none)

-

-

-

-

 Chemotherapy

0.327(0.152 ~ 0.705)

0.004

0.381(0.177 ~ 0.821)

0.014

 Chemo plus radiotherapy

0.061(0.024 ~ 0.157)

 < 0.001

0.078(0.031 ~ 0.197)

 < 0.001

Surgical method (reference: laparoscope)

0.760(0.353 ~ 1.636)

0.483

0.695(0.319 ~ 1.515)

0.361

Ovarian status (reference: ovarian transposition)

2.585(1.090 ~ 6.130)

0.031

2.388(1.060 ~ 5.381)

0.036

Intraoperative blood loss (ml) (reference: ≤ 250)

1.690(0.911 ~ 3.134)

0.096

1.588(0.861 ~ 2.927)

0.139

Perioperative complications (reference: none)

2.277(1.249 ~ 4.150)

0.007

2.102(1.159 ~ 3.813)

0.014

Pathological type (reference: squamous cell carcinoma)

-

-

-

-

 Adenocarcinoma

1.197(0.555 ~ 2.581)

0.646

1.098(0.511 ~ 2.359)

0.811

 Adeno-squamous carcinoma

1.276(0.392 ~ 4.158)

0.686

1.185(0.364 ~ 3.851)

0.778

Tumor size (cm) (reference: ≤ 4)

1.564(0.875 ~ 2.796)

0.131

1.519(0.861 ~ 2.679)

0.149

LNR (reference: ≤ 0.3)

4.643(2.572 ~ 8.381)

 < 0.001

4.490(2.505 ~ 8.050)

 < 0.001

DSI (reference: ≤ 1/2)

3.208(0.774 ~ 13.294)

0.108

3.620(0.866 ~ 15.136)

0.078

LVSI (reference: negative)

2.283(1.192 ~ 4.371)

0.013

2.013(1.070 ~ 3.787)

0.030

Vaginal margin (reference: negative)

1.607(0.901 ~ 2.866)

0.108

1.507(0.853 ~ 2.663)

0.158

Parametrium (reference: negative)

2.381(1.108 ~ 5.113)

0.026

2.621(1.264 ~ 5.434)

0.010

NLR (reference: ≤ 3.8)

2.694(1.357 ~ 5.349)

0.005

3.397(1.745 ~ 6.612)

 < 0.001

  1. LNR Lymph node ratio, DSI Deep stromal infiltration, LVSI Lymph vascular space invasion, NLR Neutrophil–lymphocyte ratio, CI Confidence intervals, HR Hazard ratio