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Table 1 The association between characteristics of the cohort and lymphatic metastasis in level IIB

From: Patterns of lymph node metastasis in level IIB and contralateral level VI for papillary thyroid carcinoma with pN1b and safety of low collar extended incision for neck dissection in level II

Clinical characters

Number(%)

Lymph node positive number in level IIB(%)

Univariate

P value

Multivariate

P value

Gender

 Female

141(64.7)

15(10.6)

0.289

–

 Male

77(35.3)

12(15.6)

  

Age

  < 55

198(90.8)

22(11.1)

0.072

–

  >  = 55

20(9.2)

5(25.0)

  

BMI

  <  = 23.9

129(59.2)

16(12.4)

0.992

–

  > 23.9

89(40.8)

11(12.3)

  

Tumor sides

 Unilateral cancer

137(62.8)

15(10.9)

0.402

–

 Bilateral cancer

81(37.2)

12(14.8)

  

Multifocality

 No

152(69.7)

19(12.5)

0.938

–

 Yes

66(30.3)

8(12.1)

  

T stage

  

0.549

 

 T1,2,3a

207(95)

25(12.1)

 

–

 T3b,4a,4b

11(5)

2(18.2)

  

Braf(20 cases)

  

0.274

 

 Negative

7(35.0)

0(0)

 

–

 Positive

13(65.0)

2(15.4)

  

PN1b

 Unilateral lymph node metastasis

187(85.8)

15(8.0)

0.000

0.159

 Bilateral lymph node metastasis

31(14.2)

12(38.7)

  

IIA Positive

  

0.001

 

 No

111(50.9)

6(5.4)

 

0.010

 Yes

107(49.1)

21(19.6)

  

IIB Positive

 No

191(87.6)

   

 Yes

27(12.4)

   

III Positive

  

0.808

 

 No

44(20.2)

5(11.4)

  

 Yes

173(79.4)

22(12.7)

 

–

IV Positive

  

0.476

 

 No

61(28)

6(9.8)

 

–

 Yes

157(72)

21

  

V Positive

  

0.186

 

 No

211(96.8)

25(11.8)

 

–

 Yes

7(3.2)

2(28.6)

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