Table 4 Immunohistochemical results of the present five patients with breast cancer with signet ring cell differentiation
Protein | Patient 1 | Patient 2 | Patient 3 | Patient 4 | Patient 5 |
|---|---|---|---|---|---|
ER | + + + (90%) | + + + (90%) | + + + (90%) | + + + (90%) | + + + (90%) |
PR | + + + (90%) | - | + + + (10%) | + + + (90%) | - |
HER2 | - | - | - | - | - |
GCDFP15 | + | - | - | - | + |
GATA3 | + | + | + | + | + |
CK7 | + | + | - | + | + |
CK20 | - | - | - | - | - |
CK5/6 | - | - | - | - | - |
MUC1 | + | + | + | + | + |
MUC2 | + | + | + | + | + |
Villin | - | - | + | - | - |
CDX2 | - | - | - | - | - |
COX2 | - | - | - | + | - |
SATB2 | - | - | - | - | - |
WT-1 | + | - | - | + | - |
PAX8 | - | - | - | - | - |
TTF-1 | - | - | - | - | - |
NapsinA | - | - | - | - | - |
Syn | - | - | - | + | - |
CgA | - | - | - | + | - |
CD56 | - | - | - | + | - |
Ki67 | + (10%) | + (25%) | + (30%) | + (15%) | + (20%) |