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Table 3 Univariate and multivariate Cox regression analyses estimating the risk factors of OS in thymoma patients

From: Prognostic factors in patients with thymoma who underwent surgery

Variable

Univariate analyses

Multivariate analyses

HR

95% CI

P value

HR

95% CI

P value

Age

2.971

0.976 ~ 7.982

0.056

   

Gender

1.462

0.506 ~ 4.220

0.483

   

KPS

1.400

0.484 ~ 4.048

0.535

   

Smoking

1.921

0.664 ~ 5.555

0.228

   

Myasthenia gravis

2.162

0.757 ~ 6.181

0.15

   

Surgical approach

1.214

0.418 ~ 3.525

0.722

   

Tumor size

1.750

0.606 ~ 5.054

0.301

   

Resection status

1.196

0.415 ~ 3.250

0.740

   

WHO classification

2.277

1.040 ~ 4.987

0.040

1.906

0.893 ~ 4.069

0.096

Masaoka-Koga stage

2.031

0.704 ~ 5.858

0.190

   

Ki-67

1.228

0.329 ~ 4.577

0.760

   

Neutrophil

7.179

1.958 ~ 25.961

0.003

5.000

1.214 ~ 20.586

0.026

NLR

5.646

1.932 ~ 16.504

0.002

2.499

0.727 ~ 8.590

0.146

Adjuvant radiotherapy

0.654

0.219 ~ 1.959

0.448

   

Adjuvant chemotherapy

2.256

0.780 ~ 6.526

0.133

   
  1. Abbreviations: OS overall survival, HR hazard ratio, CI confidence interval, KPS Karnofsky Performance Status Scale, WHO World Health Organization, NLR neutrophil-to-lymphocyte ratio